메뉴 건너뛰기




Volumn 9, Issue , 2010, Pages

Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CERAMIDE; CHOLESTEROL; EDELFOSINE; ERUCYLPHOSPHOCHOLINE; GLYCEROLIPID; MILTEFOSINE; PERIFOSINE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; SPHINGOLIPID; SPHINGOMYELIN; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; DRUG DERIVATIVE; PHOSPHORYLCHOLINE;

EID: 77951761725     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-9-33     Document Type: Review
Times cited : (49)

References (70)
  • 1
    • 52949108830 scopus 로고    scopus 로고
    • Anticancer alkylphospholipids: Mechanisms of action, cellular sensitivity and resistance, and clinical prospects
    • 10.2174/138161208785294636. 18691116
    • Anticancer alkylphospholipids: mechanisms of action, cellular sensitivity and resistance, and clinical prospects. WJ van Blitterswijk M Verheij, Curr Pharm Des 2008 14 2061 2074 10.2174/138161208785294636 18691116
    • (2008) Curr Pharm des , vol.14 , pp. 2061-2074
    • Van Blitterswijk, W.J.1    Verheij, M.2
  • 2
    • 0032484590 scopus 로고    scopus 로고
    • The antiproliferative effect of hexadecylphosphocholine toward HL60 cells is prevented by exogenous lysophosphatidylcholine
    • 9443598
    • The antiproliferative effect of hexadecylphosphocholine toward HL60 cells is prevented by exogenous lysophosphatidylcholine. K Boggs CO Rock S Jackowski, Biochim Biophys Acta 1998 1389 1 12 9443598
    • (1998) Biochim Biophys Acta , vol.1389 , pp. 1-12
    • Boggs, K.1    Rock, C.O.2    Jackowski, S.3
  • 3
    • 0032079477 scopus 로고    scopus 로고
    • Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine
    • 10.1074/jbc.273.18.11025. 9556584
    • Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine. T Wieder CE Orfanos CC Geilen, J Biol Chem 1998 273 11025 31 10.1074/jbc.273.18.11025 9556584
    • (1998) J Biol Chem , vol.273 , pp. 11025-31
    • Wieder, T.1    Orfanos, C.E.2    Geilen, C.C.3
  • 4
    • 0035885286 scopus 로고    scopus 로고
    • Effects of miltefosine on various biochemical parameters in a panel of tumor cell lines with different sensitivities
    • 10.1016/S0006-2952(01)00715-8. 11551522
    • Effects of miltefosine on various biochemical parameters in a panel of tumor cell lines with different sensitivities. M Rybczynska M Spitaler NG Knebel G Boeck H Grunicke J Hofmann, Biochem Pharmacol 2001 62 765 772 10.1016/S0006-2952(01)00715-8 11551522
    • (2001) Biochem Pharmacol , vol.62 , pp. 765-772
    • Rybczynska, M.1    Spitaler, M.2    Knebel, N.G.3    Boeck, G.4    Grunicke, H.5    Hofmann, J.6
  • 5
    • 0036305933 scopus 로고    scopus 로고
    • Structure-activity relationships of alkylphosphocholine derivatives: Antineoplastic action on brain tumor cell lines in vitro
    • 10.1007/s00280-002-0440-8. 12111115
    • Structure-activity relationships of alkylphosphocholine derivatives: antineoplastic action on brain tumor cell lines in vitro. V Jendrossek K Hammersen B Erdlenbruch W Kugler R Krugener H Eibl M Lakomek, Cancer Chemother Pharmacol 2002 50 71 79 10.1007/s00280-002-0440-8 12111115
    • (2002) Cancer Chemother Pharmacol , vol.50 , pp. 71-79
    • Jendrossek, V.1    Hammersen, K.2    Erdlenbruch, B.3    Kugler, W.4    Krugener, R.5    Eibl, H.6    Lakomek, M.7
  • 6
    • 0030037465 scopus 로고    scopus 로고
    • Early stage monitoring of miltefosine induced apoptosis in KB cells by multinuclear NMR spectroscopy
    • 8694511
    • Early stage monitoring of miltefosine induced apoptosis in KB cells by multinuclear NMR spectroscopy. J Engelmann J Henke W Willker B Kutscher G Nössner J Engel D Leibfritz, Anticancer Res 1996 16 1429 1439 8694511
    • (1996) Anticancer Res , vol.16 , pp. 1429-1439
    • Engelmann, J.1    Henke, J.2    Willker, W.3    Kutscher, B.4    Nössner, G.5    Engel, J.6    Leibfritz, D.7
  • 7
    • 0033380515 scopus 로고    scopus 로고
    • Miltefosine as a topical treatment for cutaneous metastases in breast carcinoma
    • 10.1007/s002800051114. 10602908
    • Miltefosine as a topical treatment for cutaneous metastases in breast carcinoma. S Clive J Gardiner RC Leonard, Cancer Chemother Pharmacol 1999 44 Suppl 29 30 10.1007/s002800051114 10602908
    • (1999) Cancer Chemother Pharmacol , vol.44 , Issue.SUPPL , pp. 1929-30
    • Clive, S.1    Gardiner, J.2    Leonard, R.C.3
  • 8
    • 65549098612 scopus 로고    scopus 로고
    • Cellular transport and lipid interactions of miltefosine
    • 10.2174/138920009787846332. 19442087
    • Cellular transport and lipid interactions of miltefosine. G Barratt M Saint-Pierre-Chazalet PM Loiseau, Curr Drug Metab 2009 10 247 255 10.2174/138920009787846332 19442087
    • (2009) Curr Drug Metab , vol.10 , pp. 247-255
    • Barratt, G.1    Saint-Pierre-Chazalet, M.2    Loiseau, P.M.3
  • 9
    • 34547123823 scopus 로고    scopus 로고
    • Oral miltefosine to treat leishmaniasis
    • 17361856
    • Oral miltefosine to treat leishmaniasis. J Soto P Soto, Biomedica 2006 26 Suppl 1 207 217 17361856
    • (2006) Biomedica , vol.26 , Issue.SUPPL 1 , pp. 207-217
    • Soto, J.1    Soto, P.2
  • 10
    • 34247118212 scopus 로고    scopus 로고
    • Miltefosine affects lipid metabolism in Leishmania donovani promastigotes
    • 10.1128/AAC.01123-06. 17242145
    • Miltefosine affects lipid metabolism in Leishmania donovani promastigotes. M Rakotomanga S Blanc K Gaudin P Chaminade PM Loiseau, Antimicrob Agents Chemother 2007 51 1425 1430 10.1128/AAC.01123-06 17242145
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 1425-1430
    • Rakotomanga, M.1    Blanc, S.2    Gaudin, K.3    Chaminade, P.4    Loiseau, P.M.5
  • 12
    • 0036840473 scopus 로고    scopus 로고
    • Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi
    • 10.1128/AAC.46.11.3472-3477.2002. 12384352
    • Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi. VB Saraiva D Gibaldi JO Previato L Mendonca-Previato MT Bozza CG Freire-de-Lima N Heise, Antimicrob Agents Chemother 2002 46 3472 3477 10.1128/AAC.46.11.3472-3477.2002 12384352
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3472-3477
    • Saraiva, V.B.1    Gibaldi, D.2    Previato, J.O.3    Mendonca-Previato, L.4    Bozza, M.T.5    Freire-De-Lima, C.G.6    Heise, N.7
  • 14
    • 0032813920 scopus 로고    scopus 로고
    • Mechanisms of action of phospholipid analogs as anticancer compounds
    • 10.1016/S0163-7827(99)00004-1. 10664795
    • Mechanisms of action of phospholipid analogs as anticancer compounds. T Wieder W Reutter CE Orfanos CC Geilen, Prog Lipid Res 1999 38 249 259 10.1016/S0163-7827(99)00004-1 10664795
    • (1999) Prog Lipid Res , vol.38 , pp. 249-259
    • Wieder, T.1    Reutter, W.2    Orfanos, C.E.3    Geilen, C.C.4
  • 15
    • 0029994658 scopus 로고    scopus 로고
    • Induction of resistance to hexadecylphosphocholine in the highly sensitive human epidermoid tumour cell line KB
    • 10.1016/0959-8049(95)00566-8. 8814699
    • Induction of resistance to hexadecylphosphocholine in the highly sensitive human epidermoid tumour cell line KB. EA Fleer D Berkovic U Grunwald W Hiddemann, Eur J Cancer 1996 32A 506 511 10.1016/0959-8049(95)00566-8 8814699
    • (1996) Eur J Cancer , vol.32 , pp. 506-511
    • Fleer, E.A.1    Berkovic, D.2    Grunwald, U.3    Hiddemann, W.4
  • 17
    • 0028010056 scopus 로고
    • Uptake, subcellular distribution and metabolism of the phospholipid analogue hexadecylphosphocholine in MDCK cells
    • 8123677
    • Uptake, subcellular distribution and metabolism of the phospholipid analogue hexadecylphosphocholine in MDCK cells. CC Geilen T Wieder A Haase W Reutter DM Morré DJ Morré Biochim Biophys Acta 1994 1211 14 22 8123677
    • (1994) Biochim Biophys Acta , vol.1211 , pp. 14-22
    • Geilen, C.C.1    Wieder, T.2    Haase, A.3    Reutter, W.4    Morré, D.M.5    Morré, D.J.6
  • 18
    • 0141817992 scopus 로고    scopus 로고
    • Effects of etherlipid analogs on cell membrane functions
    • 10.1046/j.1359-4117.2003.01094.x. 14567289
    • Effects of etherlipid analogs on cell membrane functions. D Berkovic JH Wernicke EA Fleer, J Exp Ther Oncol 2003 3 185 193 10.1046/j.1359-4117.2003. 01094.x 14567289
    • (2003) J Exp Ther Oncol , vol.3 , pp. 185-193
    • Berkovic, D.1    Wernicke, J.H.2    Fleer, E.A.3
  • 19
    • 0032763675 scopus 로고    scopus 로고
    • Changes of intracellular calcium, fatty acids and phospholipids during miltefosine induced apoptosis monitored by fluorescence- and 13C NMR-spectroscopy
    • 10628349
    • Changes of intracellular calcium, fatty acids and phospholipids during miltefosine induced apoptosis monitored by fluorescence- and 13C NMR-spectroscopy. J Henke J Engelmann B Kutscher G Nossner J Engel R Voegeli D Leibfritz, Anticancer Res 1999 19 4027 4032 10628349
    • (1999) Anticancer Res , vol.19 , pp. 4027-4032
    • Henke, J.1    Engelmann, J.2    Kutscher, B.3    Nossner, G.4    Engel, J.5    Voegeli, R.6    Leibfritz, D.7
  • 20
    • 0030223112 scopus 로고    scopus 로고
    • Hexadecylphosphocholine inhibits phosphatidylinositol and phosphatidylcholine phospholipase C in human leukemia cells
    • 9414418
    • Hexadecylphosphocholine inhibits phosphatidylinositol and phosphatidylcholine phospholipase C in human leukemia cells. D Berkovic M Goeckenjan S Luders W Hiddemann EA Fleer, J Exp Ther Oncol 1996 1 302 311 9414418
    • (1996) J Exp Ther Oncol , vol.1 , pp. 302-311
    • Berkovic, D.1    Goeckenjan, M.2    Luders, S.3    Hiddemann, W.4    Fleer, E.A.5
  • 21
    • 0342547155 scopus 로고    scopus 로고
    • Differential regulation of phospholipase A2 in human leukemia cells by the etherphospholipid analogue hexadecylphosphocholine
    • 10.1016/S0006-2952(97)00095-6. 9264326
    • Differential regulation of phospholipase A2 in human leukemia cells by the etherphospholipid analogue hexadecylphosphocholine. D Berkovic S Luders M Goeckenjan W Hiddemann EA Fleer, Biochem Pharmacol 1997 53 1725 1733 10.1016/S0006-2952(97)00095-6 9264326
    • (1997) Biochem Pharmacol , vol.53 , pp. 1725-1733
    • Berkovic, D.1    Luders, S.2    Goeckenjan, M.3    Hiddemann, W.4    Fleer, E.A.5
  • 22
    • 0035280546 scopus 로고    scopus 로고
    • Modulation of phospholipase D by hexadecylphosphorylcholine: A putative novel mechanism for its antitumoral activity
    • 10.1038/sj.onc.1204216. 11314048
    • Modulation of phospholipase D by hexadecylphosphorylcholine: a putative novel mechanism for its antitumoral activity. L Lucas R Hernndez-Alcoceba V Penalva JC Lacal, Oncogene 2001 20 1110 1117 10.1038/sj.onc.1204216 11314048
    • (2001) Oncogene , vol.20 , pp. 1110-1117
    • Lucas, L.1    Hernndez-Alcoceba, R.2    Penalva, V.3    Lacal, J.C.4
  • 23
    • 0032484959 scopus 로고    scopus 로고
    • The inhibition of cell signaling pathways by antitumor ether lipids
    • 9487143
    • The inhibition of cell signaling pathways by antitumor ether lipids. G Arthur R Bittman, Biochim Biophys Acta 1998 1390 85 102 9487143
    • (1998) Biochim Biophys Acta , vol.1390 , pp. 85-102
    • Arthur, G.1    Bittman, R.2
  • 24
    • 0035254650 scopus 로고    scopus 로고
    • Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis
    • 10.1016/S0360-3016(00)01476-0. 11173135
    • Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis. GA Ruiter M Verheij SF Zerp WJ van Blitterswijk, Int J Radiat Oncol Biol Phys 2001 49 415 419 10.1016/S0360-3016(00)01476-0 11173135
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 415-419
    • Ruiter, G.A.1    Verheij, M.2    Zerp, S.F.3    Van Blitterswijk, W.J.4
  • 25
    • 0032189615 scopus 로고    scopus 로고
    • Cytotoxic etherphospholipid analogues
    • DOI 10.1016/S0306-3623(98)00081-0, PII S0306362398000810
    • Cytotoxic etherphospholipid analogues. D Berkovic, Gen Pharmacol 1998 31 511 517 10.1016/S0306-3623(98)00081-0 9792208 (Pubitemid 28458917)
    • (1998) General Pharmacology , vol.31 , Issue.4 , pp. 511-517
    • Berkovic, D.1
  • 26
    • 0029023819 scopus 로고
    • The effect of two synthetic phospholipids on cell proliferation and phosphatidylcholine biosynthesis in Madin-Darby canine kidney cells
    • 10.1007/BF02536296. 7637558
    • The effect of two synthetic phospholipids on cell proliferation and phosphatidylcholine biosynthesis in Madin-Darby canine kidney cells. T Wieder A Haase CC Geilen CE Orfanos, Lipids 1995 30 389 393 10.1007/BF02536296 7637558
    • (1995) Lipids , vol.30 , pp. 389-393
    • Wieder, T.1    Haase, A.2    Geilen, C.C.3    Orfanos, C.E.4
  • 27
    • 0027232012 scopus 로고
    • Antagonism of phorbol-ester-stimulated phosphatidylcholine biosynthesis by the phospholipid analogue hexadecylphosphocholine
    • 8387273
    • Antagonism of phorbol-ester-stimulated phosphatidylcholine biosynthesis by the phospholipid analogue hexadecylphosphocholine. T Wieder CC Geilen W Reutter, Biochem J 1993 291 561 567 8387273
    • (1993) Biochem J , vol.291 , pp. 561-567
    • Wieder, T.1    Geilen, C.C.2    Reutter, W.3
  • 28
    • 0036381777 scopus 로고    scopus 로고
    • Hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis and the proliferation of HepG2 cells
    • 10.1046/j.1432-1033.2002.03169.x. 12230578
    • Hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis and the proliferation of HepG2 cells. JM Jiménez-Lápez MP Carrasco JL Segovia C Marco, Eur J Biochem 2002 269 4649 4655 10.1046/j.1432-1033.2002. 03169.x 12230578
    • (2002) Eur J Biochem , vol.269 , pp. 4649-4655
    • Jiménez-Lápez, J.M.1    Carrasco, M.P.2    Segovia, J.L.3    Marco, C.4
  • 29
    • 0026726606 scopus 로고
    • Hexadecylphosphocholine inhibits translocation of CTP:choline-phosphate cytidylyltransferase in Madin-Darby canine kidney cells
    • 1313020
    • Hexadecylphosphocholine inhibits translocation of CTP:choline-phosphate cytidylyltransferase in Madin-Darby canine kidney cells. CC Geilen T Wieder W Reutter, J Biol Chem 1992 267 6719 6724 1313020
    • (1992) J Biol Chem , vol.267 , pp. 6719-6724
    • Geilen, C.C.1    Wieder, T.2    Reutter, W.3
  • 30
    • 0029560295 scopus 로고
    • Alkylphosphocholines inhibit choline uptake and phosphatidylcholine biosynthesis in rat symphatetic neurons and impair axonal extension
    • 8526849
    • Alkylphosphocholines inhibit choline uptake and phosphatidylcholine biosynthesis in rat symphatetic neurons and impair axonal extension. E Posse de Chaves DE Vance RB Campenot JE Vance, Biochem J 1995 312 411 417 8526849
    • (1995) Biochem J , vol.312 , pp. 411-417
    • Posse De Chaves, E.1    Vance, D.E.2    Campenot, R.B.3    Vance, J.E.4
  • 31
    • 0029620193 scopus 로고
    • Effects of hexadecylphosphocholine on membrane phospholipid metabolism in human tumour cells
    • 10.1016/0959-8049(95)00350-9. 8562169
    • Effects of hexadecylphosphocholine on membrane phospholipid metabolism in human tumour cells. D Berkovic U Grunwald W Menzel C Unger W Hiddemann EA Fleer, Eur J Cancer 1995 31A 2080 2085 10.1016/0959-8049(95)00350-9 8562169
    • (1995) Eur J Cancer , vol.31 , pp. 2080-2085
    • Berkovic, D.1    Grunwald, U.2    Menzel, W.3    Unger, C.4    Hiddemann, W.5    Fleer, E.A.6
  • 32
    • 0037131168 scopus 로고    scopus 로고
    • Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis
    • 10.1074/jbc.M203176200. 12183451
    • Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis. AH van der Luit M Budde P Ruurs M Verheij WJ van Blitterswijk, J Biol Chem 2002 277 39541 39547 10.1074/jbc.M203176200 12183451
    • (2002) J Biol Chem , vol.277 , pp. 39541-39547
    • Van Der Luit, A.H.1    Budde, M.2    Ruurs, P.3    Verheij, M.4    Van Blitterswijk, W.J.5
  • 33
    • 34548073046 scopus 로고    scopus 로고
    • A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells
    • 10.1158/1535-7163.MCT-07-0202. 17699729
    • A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells. AH van der Luit SR Vink JB Klarenbeek D Perrissoud E Solary M Verheij WJ van Blitterswijk, Mol Cancer Ther 2007 6 2337 2345 10.1158/1535-7163.MCT-07-0202 17699729
    • (2007) Mol Cancer Ther , vol.6 , pp. 2337-2345
    • Van Der Luit, A.H.1    Vink, S.R.2    Klarenbeek, J.B.3    Perrissoud, D.4    Solary, E.5    Verheij, M.6    Van Blitterswijk, W.J.7
  • 34
    • 0025769543 scopus 로고
    • The phospholipid analogue hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis in Madin-Darby canine kidney cells
    • 10.1016/0014-5793(91)81018-4. 1879545
    • The phospholipid analogue hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis in Madin-Darby canine kidney cells. R Haase T Wieder CC Geilen W Reutter, FEBS Lett 1991 288 129 132 10.1016/0014-5793(91) 81018-4 1879545
    • (1991) FEBS Lett , vol.288 , pp. 129-132
    • Haase, R.1    Wieder, T.2    Geilen, C.C.3    Reutter, W.4
  • 35
    • 33644831970 scopus 로고    scopus 로고
    • Hexadecylphosphocholine disrupts cholesterol homeostasis and induces the accumulation of free cholesterol in HepG2 tumour cells
    • 10.1016/j.bcp.2005.08.001. 16466701
    • Hexadecylphosphocholine disrupts cholesterol homeostasis and induces the accumulation of free cholesterol in HepG2 tumour cells. JM Jiménez- Lápez MP Carrasco C Marco JL Segovia, Biochem Pharmacol 2006 71 1114 1121 10.1016/j.bcp.2005.08.001 16466701
    • (2006) Biochem Pharmacol , vol.71 , pp. 1114-1121
    • Jiménez-Lápez, J.M.1    Carrasco, M.P.2    Marco, C.3    Segovia, J.L.4
  • 36
    • 0242380198 scopus 로고    scopus 로고
    • Hexadecylphosphocholine inhibits phosphatidylcholine synthesis via both the methylation of phosphatidylethanolamine and CDP-choline pathways in HepG2 cells
    • 10.1016/S1357-2725(03)00193-6. 14592540
    • Hexadecylphosphocholine inhibits phosphatidylcholine synthesis via both the methylation of phosphatidylethanolamine and CDP-choline pathways in HepG2 cells. JM Jiménez-Lápez MP Carrasco JL Segovia C Marco, Int J Biochem Cell Biol 2004 36 153 161 10.1016/S1357-2725(03)00193-6 14592540
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 153-161
    • Jiménez-Lápez, J.M.1    Carrasco, M.P.2    Segovia, J.L.3    Marco, C.4
  • 37
    • 0028979984 scopus 로고
    • Effect of 1-O-octadecyl-2-O-methyl-glycerophosphocholine on phosphatidylcholine and phosphatidylethanolamine synthesis in MCF-7 and A549 cells and its relationship to inhibition of cell proliferation
    • 10.1111/j.1432-1033.1995.tb20887.x. 7588730
    • Effect of 1-O-octadecyl-2-O-methyl-glycerophosphocholine on phosphatidylcholine and phosphatidylethanolamine synthesis in MCF-7 and A549 cells and its relationship to inhibition of cell proliferation. X Zhou G Arthur, Eur J Biochem 1995 232 881 888 10.1111/j.1432-1033.1995.tb20887.x 7588730
    • (1995) Eur J Biochem , vol.232 , pp. 881-888
    • Zhou, X.1    Arthur, G.2
  • 38
    • 0036009622 scopus 로고    scopus 로고
    • Effects of hexadecylphosphocholine on phosphatidylcholine and phosphatidylserine metabolism in human lymphoma cells
    • 10.1046/j.1359-4117.2002.01014.x. 12415624
    • Effects of hexadecylphosphocholine on phosphatidylcholine and phosphatidylserine metabolism in human lymphoma cells. D Berkovic S Sievers D Haase EA Fleer C Binder, J Exp Ther Oncol 2002 2 85 92 10.1046/j.1359-4117.2002. 01014.x 12415624
    • (2002) J Exp Ther Oncol , vol.2 , pp. 85-92
    • Berkovic, D.1    Sievers, S.2    Haase, D.3    Fleer, E.A.4    Binder, C.5
  • 39
    • 60349120180 scopus 로고    scopus 로고
    • Hexadecylphosphocholine alters nonvesicular cholesterol traffic from the plasma membrane to the endoplasmic reticulum and inhibits the synthesis of sphingomyelin in HepG2 cells
    • 10.1016/j.biocel.2008.11.004. 19084611
    • Hexadecylphosphocholine alters nonvesicular cholesterol traffic from the plasma membrane to the endoplasmic reticulum and inhibits the synthesis of sphingomyelin in HepG2 cells. C Marco JM Jiménez-Lápez P Ríos-Marco JL Segovia MP Carrasco, Int J Biochem Cell Biol 2009 41 1296 1303 10.1016/j.biocel.2008.11.004 19084611
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 1296-1303
    • Marco, C.1    Jiménez-Lápez, J.M.2    Ríos-Marco, P.3    Segovia, J.L.4    Carrasco, M.P.5
  • 40
    • 0036638615 scopus 로고    scopus 로고
    • Hexadecylphosphocholine does not influence phospholipase D and sphingomyelinase activity in human leukemia cells
    • 10.1046/j.1359-4117.2002.01036.x. 12416025
    • Hexadecylphosphocholine does not influence phospholipase D and sphingomyelinase activity in human leukemia cells. D Berkovic K Berkovic C Binder D Haase EA Fleer, J Exp Ther Oncol 2002 2 213 218 10.1046/j.1359-4117. 2002.01036.x 12416025
    • (2002) J Exp Ther Oncol , vol.2 , pp. 213-218
    • Berkovic, D.1    Berkovic, K.2    Binder, C.3    Haase, D.4    Fleer, E.A.5
  • 41
    • 3042853044 scopus 로고    scopus 로고
    • Intracellular cholesterol transport
    • 10.1161/01.ATV.0000131264.66417.d5. 15130918
    • Intracellular cholesterol transport. RE Soccio JL Breslow, Arterioscler Thromb Vasc Biol 2004 24 1150 1160 10.1161/01.ATV.0000131264.66417.d5 15130918
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1150-1160
    • Soccio, R.E.1    Breslow, J.L.2
  • 42
    • 33749073795 scopus 로고    scopus 로고
    • Cholesterol sensing, trafficking, and esterification
    • 10.1146/annurev.cellbio.22.010305.104656. 16753029
    • Cholesterol sensing, trafficking, and esterification. T Chang CCY Chang N Ohgami Y Yamauchi, Annu Rev Cell Dev Biol 2006 22 129 157 10.1146/annurev. cellbio.22.010305.104656 16753029
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 129-157
    • Chang, T.1    Chang, C.C.Y.2    Ohgami, N.3    Yamauchi, Y.4
  • 43
    • 33745018593 scopus 로고    scopus 로고
    • Dynamin is involved in endolysosomal cholesterol delivery to the endoplasmic reticulum: Role in cholesterol homeostasis
    • 10.1111/j.1600-0854.2006.00435.x. 16787396
    • Dynamin is involved in endolysosomal cholesterol delivery to the endoplasmic reticulum: role in cholesterol homeostasis. P Robinet A Fradagrada M Monier M Marchetti A Cogny N Moatti J Paul B Vedie C Lamaze, Traffic 2006 7 811 823 10.1111/j.1600-0854.2006.00435.x 16787396
    • (2006) Traffic , vol.7 , pp. 811-823
    • Robinet, P.1    Fradagrada, A.2    Monier, M.3    Marchetti, M.4    Cogny, A.5    Moatti, N.6    Paul, J.7    Vedie, B.8    Lamaze, C.9
  • 44
    • 0037697148 scopus 로고    scopus 로고
    • Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol
    • 10.1074/jbc.M300542200. 12721287
    • Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol. S Sugii PC Reid N Ohgami H Du T Chang, J Biol Chem 2003 278 27180 27189 10.1074/jbc.M300542200 12721287
    • (2003) J Biol Chem , vol.278 , pp. 27180-27189
    • Sugii, S.1    Reid, P.C.2    Ohgami, N.3    Du, H.4    Chang, T.5
  • 45
    • 0030839916 scopus 로고    scopus 로고
    • The fate of cholesterol exiting lysosomes
    • 10.1074/jbc.272.27.17018. 9202016
    • The fate of cholesterol exiting lysosomes. Y Lange J Ye J Chin, J Biol Chem 1997 272 17018 17022 10.1074/jbc.272.27.17018 9202016
    • (1997) J Biol Chem , vol.272 , pp. 17018-17022
    • Lange, Y.1    Ye, J.2    Chin, J.3
  • 46
    • 0033583562 scopus 로고    scopus 로고
    • Intracellular cholesterol transport
    • 10216277
    • Intracellular cholesterol transport. L Liscum NJ Munn, Biochim Biophys Acta 1999 1438 19 37 10216277
    • (1999) Biochim Biophys Acta , vol.1438 , pp. 19-37
    • Liscum, L.1    Munn, N.J.2
  • 47
    • 0036424016 scopus 로고    scopus 로고
    • Cholesterol trafficking in the secretory and endocytic systems
    • 10.1016/S1084-9521(02)00048-4. 12137740
    • Cholesterol trafficking in the secretory and endocytic systems. W Prinz, Semin Cell Dev Biol 2002 13 197 203 10.1016/S1084-9521(02)00048-4 12137740
    • (2002) Semin Cell Dev Biol , vol.13 , pp. 197-203
    • Prinz, W.1
  • 48
    • 30344473341 scopus 로고    scopus 로고
    • Protein sensors for membrane sterols
    • 10.1016/j.cell.2005.12.022. 16413480
    • Protein sensors for membrane sterols. JL Goldstein RA DeBose-Boyd MS Brown, Cell 2006 124 35 46 10.1016/j.cell.2005.12.022 16413480
    • (2006) Cell , vol.124 , pp. 35-46
    • Goldstein, J.L.1    Debose-Boyd, R.A.2    Brown, M.S.3
  • 49
    • 33846511087 scopus 로고    scopus 로고
    • Intracellular sterol transport in eukaryotes, a connection to mitochondrial function?
    • 10.1016/j.biochi.2006.07.022. 16945463
    • Intracellular sterol transport in eukaryotes, a connection to mitochondrial function? R Schneiter, Biochimie 2007 89 255 259 10.1016/j.biochi.2006.07.022 16945463
    • (2007) Biochimie , vol.89 , pp. 255-259
    • Schneiter, R.1
  • 50
    • 34249991703 scopus 로고    scopus 로고
    • Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein
    • 10.1515/BC.2007.063. 17552909
    • Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein. JO Babalola M Wendeler B Breiden C Arenz G Schwarzmann S Locatelli-Hoops K Sandhoff, Biol Chem 2007 388 617 626 10.1515/BC.2007.063 17552909
    • (2007) Biol Chem , vol.388 , pp. 617-626
    • Babalola, J.O.1    Wendeler, M.2    Breiden, B.3    Arenz, C.4    Schwarzmann, G.5    Locatelli-Hoops, S.6    Sandhoff, K.7
  • 51
    • 0031936591 scopus 로고    scopus 로고
    • Transport of cholesterol from the endoplasmic reticulum to the plasma membrane is constitutive in CaCo-2 cells and differs from the transport of plasma membrane cholesterol to the endoplasmic reticulum
    • 9507994
    • Transport of cholesterol from the endoplasmic reticulum to the plasma membrane is constitutive in CaCo-2 cells and differs from the transport of plasma membrane cholesterol to the endoplasmic reticulum. FJ Field E Born S Murthy SN Mathur, J Lipid Res 1998 39 333 343 9507994
    • (1998) J Lipid Res , vol.39 , pp. 333-343
    • Field, F.J.1    Born, E.2    Murthy, S.3    Mathur, S.N.4
  • 52
    • 0032563304 scopus 로고    scopus 로고
    • Circulation of cholesterol between lysosomes and the plasma membrane
    • 10.1074/jbc.273.30.18915. 9668068
    • Circulation of cholesterol between lysosomes and the plasma membrane. Y Lange J Ye TL Steck, J Biol Chem 1998 273 18915 18922 10.1074/jbc.273.30.18915 9668068
    • (1998) J Biol Chem , vol.273 , pp. 18915-18922
    • Lange, Y.1    Ye, J.2    Steck, T.L.3
  • 53
    • 0034947717 scopus 로고    scopus 로고
    • Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-treated cells
    • 11441133
    • Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-treated cells. A Mohammadi RJ Perry MK Storey HW Cook DM Byers ND Ridgway, J Lipid Res 2001 42 1062 1071 11441133
    • (2001) J Lipid Res , vol.42 , pp. 1062-1071
    • Mohammadi, A.1    Perry, R.J.2    Storey, M.K.3    Cook, H.W.4    Byers, D.M.5    Ridgway, N.D.6
  • 54
    • 0027994354 scopus 로고
    • Cholesterol movement from plasma membrane to rough endoplasmic reticulum. Inhibition by progesterone
    • 8106380
    • Cholesterol movement from plasma membrane to rough endoplasmic reticulum. Inhibition by progesterone. Y Lange, J Biol Chem 1994 269 3411 3414 8106380
    • (1994) J Biol Chem , vol.269 , pp. 3411-3414
    • Lange, Y.1
  • 55
    • 0034717894 scopus 로고    scopus 로고
    • Intracellular cholesterol trafficking: Role of the NPC1 protein
    • 10856720
    • Intracellular cholesterol trafficking: role of the NPC1 protein. EJ Blanchette-Mackie, Biochim Biophys Acta 2000 1486 171 183 10856720
    • (2000) Biochim Biophys Acta , vol.1486 , pp. 171-183
    • Blanchette-Mackie, E.J.1
  • 56
    • 0036186426 scopus 로고    scopus 로고
    • Dynamics of lysosomal cholesterol in Niemann-Pick type C and normal human fibroblasts
    • 11861661
    • Dynamics of lysosomal cholesterol in Niemann-Pick type C and normal human fibroblasts. Y Lange J Ye M Rigney TL Steck, J Lipid Res 2002 43 198 204 11861661
    • (2002) J Lipid Res , vol.43 , pp. 198-204
    • Lange, Y.1    Ye, J.2    Rigney, M.3    Steck, T.L.4
  • 57
    • 0038158091 scopus 로고    scopus 로고
    • The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells
    • 10.1074/jbc.M300488200. 12591922
    • The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells. KM Wojtanik L Liscum, J Biol Chem 2003 278 14850 14856 10.1074/jbc.M300488200 12591922
    • (2003) J Biol Chem , vol.278 , pp. 14850-14856
    • Wojtanik, K.M.1    Liscum, L.2
  • 58
    • 41549110288 scopus 로고    scopus 로고
    • Hexadecylphosphocholine interferes with the intracellular transport of cholesterol in HepG2 cells
    • 10.1111/j.1742-4658.2008.06322.x. 18312412
    • Hexadecylphosphocholine interferes with the intracellular transport of cholesterol in HepG2 cells. MP Carrasco JM Jiménez-Lápez JL Segovia C Marco, FEBS J 2008 275 1675 1686 10.1111/j.1742-4658.2008.06322.x 18312412
    • (2008) FEBS J , vol.275 , pp. 1675-1686
    • Carrasco, M.P.1    Jiménez-Lápez, J.M.2    Segovia, J.L.3    Marco, C.4
  • 59
    • 1542270723 scopus 로고    scopus 로고
    • Hexadecylphosphocholine interaction with lipid monolayers
    • 10.1016/j.bbamem.2004.01.010. 15003884
    • Hexadecylphosphocholine interaction with lipid monolayers. M Rakotomanga PM Loiseau M Saint-Pierre-Chazalet, Biochim Biophys Acta 2004 1661 212 218 10.1016/j.bbamem.2004.01.010 15003884
    • (2004) Biochim Biophys Acta , vol.1661 , pp. 212-218
    • Rakotomanga, M.1    Loiseau, P.M.2    Saint-Pierre-Chazalet, M.3
  • 60
    • 0030977396 scopus 로고    scopus 로고
    • Quantitation of the pool of cholesterol associated with acyl-CoA:cholesterol acyltransferase in human fibroblasts
    • 10.1074/jbc.272.20.13103. 9148923
    • Quantitation of the pool of cholesterol associated with acyl-CoA:cholesterol acyltransferase in human fibroblasts. Y Lange TL Steck, J Biol Chem 1997 272 13103 13108 10.1074/jbc.272.20.13103 9148923
    • (1997) J Biol Chem , vol.272 , pp. 13103-13108
    • Lange, Y.1    Steck, T.L.2
  • 61
    • 0034682501 scopus 로고    scopus 로고
    • Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface
    • 10.1073/pnas.140218797. 10890900
    • Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface. S Heino S Lusa P Somerharju C Ehnholm VM Olkkonen E Ikonen, Proc Natl Acad Sci USA 2000 97 8375 8380 10.1073/pnas.140218797 10890900
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8375-8380
    • Heino, S.1    Lusa, S.2    Somerharju, P.3    Ehnholm, C.4    Olkkonen, V.M.5    Ikonen, E.6
  • 62
    • 34548182369 scopus 로고    scopus 로고
    • Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the ER in CaCo-2 cells
    • 10.1194/jlr.M700029-JLR200. 17473178
    • Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the ER in CaCo-2 cells. FJ Field K Watt SN Mathur, J Lipid Res 2007 48 1735 1745 10.1194/jlr.M700029-JLR200 17473178
    • (2007) J Lipid Res , vol.48 , pp. 1735-1745
    • Field, F.J.1    Watt, K.2    Mathur, S.N.3
  • 63
    • 0030027903 scopus 로고    scopus 로고
    • Progesterone inhibits cholesterol biosynthesis in cultured cells. Accumulation of cholesterol precursors
    • 10.1074/jbc.271.5.2627. 8576232
    • Progesterone inhibits cholesterol biosynthesis in cultured cells. Accumulation of cholesterol precursors. JE Metherall K Waugh H Li, J Biol Chem 1996 271 2627 2633 10.1074/jbc.271.5.2627 8576232
    • (1996) J Biol Chem , vol.271 , pp. 2627-2633
    • Metherall, J.E.1    Waugh, K.2    Li, H.3
  • 64
    • 0031943690 scopus 로고    scopus 로고
    • Sphingomyelinase treatment induces ATP-independent endocytosis
    • 10.1083/jcb.140.1.39. 9425152
    • Sphingomyelinase treatment induces ATP-independent endocytosis. X Zha LM Pierini PL Leopold PJ Skiba I Tabas FR Maxfield, J Cell Biol 1998 140 39 47 10.1083/jcb.140.1.39 9425152
    • (1998) J Cell Biol , vol.140 , pp. 39-47
    • Zha, X.1    Pierini, L.M.2    Leopold, P.L.3    Skiba, P.J.4    Tabas, I.5    Maxfield, F.R.6
  • 65
    • 77951675862 scopus 로고    scopus 로고
    • Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membrane-targeted alkylphospholipid analogues
    • DOI:10.1111/j.1476-5381.2010.00689.x
    • Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membrane-targeted alkylphospholipid analogues. MP Carrasco JM Jiménez-Lápez P Ríos-Marco JL Segovia C Marco, Br J Pharmacol DOI:10.1111/j.1476-5381.2010.00689.x
    • Br J Pharmacol
    • Carrasco, M.P.1    Jiménez-Lápez, J.M.2    Ríos-Marco, P.3    Segovia, J.L.4    Marco, C.5
  • 66
    • 0142027805 scopus 로고    scopus 로고
    • Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
    • 10.1073/pnas.1534923100. 14512514
    • Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes. JD Horton NA Shah JA Warrington NN Anderson SW Park MS Brown JL Goldstein, Proc Natl Acad Sci USA 2003 100 12027 12032 10.1073/pnas.1534923100 14512514
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12027-12032
    • Horton, J.D.1    Shah, N.A.2    Warrington, J.A.3    Anderson, N.N.4    Park, S.W.5    Brown, M.S.6    Goldstein, J.L.7
  • 67
    • 0029558972 scopus 로고
    • Regulation of intracellular cholesterol metabolism
    • 10.1247/csf.20.421. 8825062
    • Regulation of intracellular cholesterol metabolism. R Sato T Takano, Cell Struct Funct 1995 20 421 427 10.1247/csf.20.421 8825062
    • (1995) Cell Struct Funct , vol.20 , pp. 421-427
    • Sato, R.1    Takano, T.2
  • 68
    • 0034051162 scopus 로고    scopus 로고
    • Membrane rafts and signaling by the multichain immune recognition receptors
    • 10.1016/S0952-7915(00)00084-4. 10781401
    • Membrane rafts and signaling by the multichain immune recognition receptors. C Langlet AM Bernard P Drevot HT He, Curr Opin Immunol 2000 12 250 255 10.1016/S0952-7915(00)00084-4 10781401
    • (2000) Curr Opin Immunol , vol.12 , pp. 250-255
    • Langlet, C.1    Bernard, A.M.2    Drevot, P.3    He, H.T.4
  • 69
    • 0034304851 scopus 로고    scopus 로고
    • Lipid rafts and signal transduction
    • 10.1038/35036052. 11413487
    • Lipid rafts and signal transduction. K Simons D Toomre, Nat Rev Mol Cell Biol 2000 1 31 39 10.1038/35036052 11413487
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 31-39
    • Simons, K.1    Toomre, D.2
  • 70
    • 33847289770 scopus 로고    scopus 로고
    • Rationale and clinical application of alkylphospholipid analogues in combination with radiotherapy
    • 10.1016/j.ctrv.2006.12.001. 17287087
    • Rationale and clinical application of alkylphospholipid analogues in combination with radiotherapy. SR Vink WJ van Blitterswijk JHM Schellens M Verheij, Cancer Treat Rev 2007 33 191 202 10.1016/j.ctrv.2006.12.001 17287087
    • (2007) Cancer Treat Rev , vol.33 , pp. 191-202
    • Vink, S.R.1    Van Blitterswijk, W.J.2    Schellens, J.H.M.3    Verheij, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.