Structure-activity relationships of alkylphosphocholine derivatives: Antineoplastic action on brain tumor cell lines in vitro

Cancer Chemotherapy and Pharmacology

Volumn 50, Issue 1, 2002, Pages 71-79

  Jendrossek, Verena ^a   Hammersen, Kerstin ^b   Erdlenbruch, Bernhard ^b   Kugler, Wilfried ^b   Krügener, Regina ^b   Eibl, Hansjörg ^c   Lakomek, Max ^b  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Alkylphosphocholines; Apoptosis; Erucylphosphocholine; Glioblastoma; Structure activity relationship

Indexed keywords

ALCOHOL DERIVATIVE; DOCOSENYLPHOSPHOCHOLINE; ERUCYL N,N,N TRIMETHYLPROPANOLAMINOPHOSPHATE; ERUCYLPHOSPHOCHOLINE; HENEICOSENYLPHOSPHOCHOLINE; MILTEFOSINE; NITROGEN; PHOSPHORUS; PHOSPHORYLCHOLINE; TRICOSENYLPHOSPHOCHOLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN TUMOR; CANCER CHEMOTHERAPY; CELL CYCLE; CELL GROWTH; CELL KILLING; CELL LINE; CELL VIABILITY; CHEMICAL BOND; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LC 50; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; REDUCTION; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BRAIN NEOPLASMS; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; GLIOBLASTOMA; HEMOLYSIS; HUMANS; MALE; PHOSPHORYLCHOLINE; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0036305933     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-002-0440-8     Document Type: Article

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