Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis

Journal of Biological Chemistry

Volumn 277, Issue 42, 2002, Pages 39541-39547

  Van Der Luit, Arnold H ^a   Budde, Marianne ^a   Ruurs, Paula ^a   Verheij, Marcel ^a   Van Blitterswijk, Wim J ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELL MEMBRANES; CHOLESTEROL; ENZYMES; PHOSPHOLIPIDS;

ENDOCYTOSIS;

BIOCHEMISTRY;

ANTINEOPLASTIC AGENT; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; EDELFOSINE; FILIPIN; LIPID; LYSOPHOSPHATIDYLCHOLINE; LYSOPHOSPHOLIPID; METHYL BETA CYCLODEXTRIN; PHOSPHATIDYLCHOLINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL TRANSPORT; CONTROLLED STUDY; ENDOCYTOSIS; INTERNALIZATION; ISOTOPE LABELING; LIPID ANALYSIS; LOW TEMPERATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BETA-CYCLODEXTRINS; CELL LINE; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE; CLATHRIN; CYCLODEXTRINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FILIPIN; KINETICS; LYSOPHOSPHATIDYLCHOLINES; LYSOPHOSPHOLIPIDS; MEMBRANE MICRODOMAINS; MICE; PHOSPHATIDYLCHOLINES; PROTEIN BINDING; RECEPTORS, TRANSFERRIN; SPECTROMETRY, FLUORESCENCE; TIME FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0037131168     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M203176200     Document Type: Article

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