Hexadecylphosphocholine disrupts cholesterol homeostasis and induces the accumulation of free cholesterol in HepG2 tumour cells

Biochemical Pharmacology

Volumn 71, Issue 8, 2006, Pages 1114-1121

  Jiménez López, José M ^a   Carrasco, María P ^a   Marco, Carmen ^a   Segovia, Josefa L ^a  

^a UNIVERSITY OF GRANADA   (Spain)

Author keywords

Alkylphosphocholines; Apoptosis; Cholesterol metabolism; Cholesteryl esters; Phosphatidylcholine; Sphingolipids

Indexed keywords

ACYL COENZYME A; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTERASE; CYTIDINE DIPHOSPHATE; MILTEFOSINE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; SPHINGOLIPID; SPHINGOMYELIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; ENZYME ACTIVITY; ESTERIFICATION; HOMEOSTASIS; HUMAN; HUMAN CELL; LIPID METABOLISM; METHYLATION; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL; VERO CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASES; CELL LINE, TUMOR; CERAMIDES; CERCOPITHECUS AETHIOPS; CHOLESTEROL; CHOLESTEROL ESTERS; DNA FRAGMENTATION; HOMEOSTASIS; HUMANS; PHOSPHORYLCHOLINE; SPHINGOMYELINS; VERO CELLS;

EID: 33644831970     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.08.001     Document Type: Article

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