Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation

Journal of Biological Chemistry

Volumn 285, Issue 10, 2010, Pages 7233-7245

  Giroud, Claire ^b   Moreau, Magali ^b   Mattioli, Tony A ^a   Balland, Véronique ^d   Boucher, Jean Luc ^b   Xu Li, Yun ^b   Stuehr, Dennis J ^c   Santolini, Jérôme ^a  

^a SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c LERNER RESEARCH INSTITUTE   (United States)

^d UNIVERSITÉ PARIS DIDEROT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC PROTON; ACTIVE SITE; CITRULLINE; COFACTORS; DISTAL POCKET; ELECTROSTATIC PROPERTIES; GUANIDINIUM; H-BOND NETWORK; KEY FEATURE; L-ARGININE; MOLECULAR MECHANISM; NITRIC OXIDE SYNTHASES; NITRIC-OXIDE SYNTHASE; OXIDATION PROCESS; OXIDATION REACTIONS; OXIDATIVE CHEMISTRY; OXYGEN ACTIVATIONS; REDOX POTENTIALS; STRUCTURAL MODELS; THIOLATES; VIBRATIONAL SPECTROSCOPIC TECHNIQUES;

AMINO ACIDS; ELECTROCHEMICAL PROPERTIES; MODEL STRUCTURES; NITRIC OXIDE; NONCRYSTALLINE SOLIDS; OXIDATION; OXYGEN; PORPHYRINS; PROTON TRANSFER; REDOX REACTIONS;

HEMOGLOBIN;

ARGININE GUANIDINE; GUANIDINE; HEME DERIVATIVE; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; ELECTROCHEMICAL ANALYSIS; HYDROGEN BOND; OXIDATION; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTON TRANSPORT; SPECTROSCOPY; STATIC ELECTRICITY; STRUCTURE ANALYSIS;

ANIMALS; ARGININE; BINDING SITES; CATALYTIC DOMAIN; CITRULLINE; ENZYME ACTIVATION; GUANIDINE; HEME; HYDROGEN BONDING; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATION-REDUCTION; OXYGEN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTRUM ANALYSIS, RAMAN;

EID: 77951246157     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.038240     Document Type: Article

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