nNOS at a glance: Implications for brain and brawn

Journal of Cell Science

Volumn 117, Issue 13, 2004, Pages 2627-2629

  Mungrue, Imran N ^a   Bredt, David S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM ION; CALPAIN; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; PDZ PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; RYANODINE RECEPTOR; SYNTROPHIN; UTROPHIN;

AMINO TERMINAL SEQUENCE; ARTERY MUSCLE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL FUNCTION; BRAIN NERVE CELL; CALCIUM TRANSPORT; CELLULAR DISTRIBUTION; CEREBROVASCULAR ACCIDENT; GENE MUTATION; HEART MUSCLE; HEART MUSCLE CELL; HUMAN; MUSCLE CONTRACTILITY; MUSCULAR DYSTROPHY; NERVE CELL PLASTICITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SARCOPLASMIC RETICULUM; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SMOOTH MUSCLE; SYNAPTIC TRANSMISSION; TISSUE DISTRIBUTION;

ALTERNATIVE SPLICING; ANIMALS; BRAIN; HUMANS; ISOENZYMES; MODELS, BIOLOGICAL; MUSCLE, SKELETAL; MUSCLE, SMOOTH; MYOCARDIUM; NEURONS; NITRIC OXIDE SYNTHASE; SIGNAL TRANSDUCTION;

EID: 3242880126     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01187     Document Type: Article

References (28)

1. Bia, B. L., Cassidy, P. J., Young, M. E., Rafael, J. A., Leighton, B., Davies, K. E., Radda, G. K. and Clarke, K. (1999). Decreased myocardial nNOS, increased NOS and abnormal ECGs in indicating a neural role for nitric oxide. Nature 347, 768-770.
2. Brenman, J. E., Chao, D. S., Xia, H., Aldape, K. and Bredt, D. S. (1995). Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy. Cell 82, 743-752.
3. Brenman, J. E., Chao, D. S., Gee, S. H., McGee, A. W., Craven, S. E., Santillano, D. R., Wu, Z., Huang, F., Xia, H., Peters, M. F., et al. (1996). Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alphal-syntrophin mediated by PDZ domains. Cell 84, 757-767.
4. Christopherson, K. S., Hillier, B. J., Lim, W. A. and Bredt, D. S. (1999). PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain. J. Biol. Chem. 274, 27467-27473.
5. Crosbie, R. H., Barresi, R. and Campbell, K. P. (2002). Loss of sarcolemma nNOS in sarcoglycan-deficient muscle. FASEB J. 16, 1786-1791.
6. Emery, A. E. (2002). The muscular dystrophies. Lancet 359, 687-695.
7. Fang, M., Jaffrey, S. R., Sawa, A., Ye, K., Luo, X. and Snyder, S. H. (2000). Dexras 1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. Neuron 28, 183-193.
8. Firestein, B. L. and Bredt, D. S. (1999). Interaction of neuronal nitric-oxide synthase and phosphofructokinase-M. J. Biol. Chem. 274, 10545-10550.
9. Grange, R. W., Isotani, E., Lau, K. S., Kamm, K. E., Huang, P. L. and Stull, J. T. (2001). Nitric oxide contributes to vascular smooth muscle relaxation in contracting fast-twitch muscles. Physiol. Genomics 5, 35-44.
10. Hajimohammadreza, I., Raser, K. J., Nath, R., Nadimpalli, R., Scott, M. and Wang, K. K. (1997). Neuronal nitric oxide synthase and calmodulin-dependent protein kinase IIalpha undergo neurotoxin-induced proteolysis. J. Neurochem. 69, 1006-1013.
11. Haley, J. E., Wilcox, G. L. and Chapman, P. F. (1992). The role of nitric oxide in hippocampal long-term potentiation. Neuron 8, 211-216.
12. Hara, H., Huang, P. L., Panahian, N., Fishman, M. C. and Moskowitz, M. A. (1996). Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion. J. Cereb. Blood Flow Metab. 16, 605-611.
13. Huang, Z., Huang, P. L., Panahian, N., Dalkara, T., Fishman, M. C. and Moskowitz, M. A. (1994). Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 265, 1883-1885.
14. Kim, W. K., Choi, Y. B., Rayudu, P. V., Das, P., Asaad, W., Arnelle, D. R., Stamler, J. S. and Lipton, S. A. (1999). Attenuation of NMDA receptor activity and neurotoxicity by nitroxyl anion, NO. Neuron 24, 461-469.
15. Kobzik, L., Reid, M. B., Bredt, D. S. and Stamler, J. S. (1994). Nitric oxide in skeletal muscle. Nature 372, 546-548.
16. Laine, R. and de Montellano, P. R. (1998). Neuronal nitric oxide synthase isoforms alpha and mu are closely related calpain-sensitive proteins. Mol. Pharmacol. 54, 305-312.
17. Lau, K. S., Grange, R. W., Isotani, E., Sarelius, I. H., Kamm, K. E., Huang, P. L. and Stull, J. T. (2000). nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle. Physiol. Genomics 2, 21-27.
18. Persson, M. G., Gustafsson, L. E., Wiklund, N. P., Hedqvist, P. and Moncada, S. (1990). Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo. Br. J. Pharmacol. 100, 463-466.
19. Pou, S., Pou, W. S., Bredt, D. S., Snyder, S. H. and Rosen, G. M. (1992). Generation of superoxide by purified brain nitric oxide synthase. J. Biol. Chem. 267, 24173-24176.
20. Sattler, R., Xiong, Z., Lu, W. Y., Hafner, M., MacDonald, J. F. and Tymianski, M. (1999). Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science 284, 1845-1848.
21. Schuh, K., Uldrijan, S., Telkamp, M., Rothlein, N. and Neyses, L. (2001). The plasmamembrane calmodulin-dependent calcium pump: a major regulator of nitric oxide synthase I. J. Cell Biol. 155, 201-205.
22. Schwarz, P. M., Kleinert, H. and Forstermann, U. (1999). Potential functional significance of brain-type and muscle-type nitric oxide synthase I expressed in adventitia and media of rat aorta. Arterioscler. Thromb. Vasc. Biol. 19, 2584-2590.
23. Sears, C. E., Bryant, S. M., Ashley, E. A., Lygate, C. A., Rakovic, S., Wallis, H. L., Neubauer, S., Terrar, D. A. and Casadei, B. (2003). Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling. Circ. Res. 92, E52-E59.
24. Shibuki, K. and Okada, D. (1991). Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum. Nature 349, 326-328.
25. Silvagno, F., Xia, H. and Bredt, D. S. (1996). Neuronal nitric-oxide synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle. J. Biol. Chem. 271, 11204-11208.
26. Thomas, G. D., Sander, M., Lau, K. S., Huang, P. L., Stull, J. T. and Victor, R. G. (1998). Impaired metabolic modulation of alpha-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle. Proc. Natl. Acad. Sci. USA 95, 15090-15095.
27. Wehling, M., Spencer, M. J. and Tidball, J. G. (2001). A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice. J. Cell Biol. 155, 123-131.
28. Xu, K. Y., Huso, D. L., Dawson, T. M., Bredt, D. S. and Becker, L. C. (1999). Nitric oxide synthase in cardiac sarcoplasmic reticulum. Proc. Natl. Acad. Sci. USA 96, 657-662.