Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase

Journal of Biological Chemistry

Volumn 279, Issue 36, 2004, Pages 37918-37927

  Garcin, Elsa D ^a   Bruns, Christopher M ^a   Lloyd, Sarah J ^a   Hosfield, David J ^b   Tiso, Mauro ^c   Gachhui, Ratan ^c,d   Stuehr, Dennis J ^c   Tainer, John A ^a   Getzoff, Elizabeth D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Takeda San Diego Inc   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF CALCUTTA   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON-ACCEPTING POSITION; NITRIC-OXIDE SYNTHASE (NOS);

CATALYSIS; CRYSTAL STRUCTURE; ELECTRON TRANSITIONS; ENZYMES; NITROGEN COMPOUNDS;

BIOCHEMISTRY;

ARGININE; CALMODULIN; DIMER; FLAVINE MONONUCLEOTIDE; ISOENZYME; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CRYSTAL STRUCTURE; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME INHIBITION; HOMEOSTASIS; HOST RESISTANCE; HUMAN; MUTAGENESIS; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATALYSIS; ELECTRON TRANSPORT; FLAVINS; HUMANS; ISOENZYMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PROTEIN CONFORMATION; RATS; SEQUENCE HOMOLOGY, AMINO ACID; X-RAY DIFFRACTION;

EID: 4444354274     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406204200     Document Type: Article

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