Surface charge interactions of the FMN module govern catalysis by nitric-oxide synthase

Journal of Biological Chemistry

Volumn 281, Issue 48, 2006, Pages 36819-36827

  Panda, Koustubh ^a   Haque, Mohammad Mahfuzul ^a   Garcin Hosfield, Elsa D ^b   Durra, Deborah ^a   Getzoff, Elizabeth D ^b   Stuehr, Dennis J ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ELECTRON TRANSITIONS; MOLECULAR BIOLOGY; OXYGEN; REACTION KINETICS;

ELECTRON TRANSFER; NEGATIVE CHARGE; NITRIC OXIDE SYNTHASE (NOS); OXYGEN ACTIVATION; SURFACE CHARGE;

ENZYME KINETICS;

FLAVOPROTEIN; HEME; NITRIC OXIDE SYNTHASE; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ELECTRICITY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ANIMALS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ELECTRONS; FLAVINS; HEME; MUTAGENESIS, SITE-DIRECTED; NADPH-FERRIHEMOPROTEIN REDUCTASE; NEURONS; NITRIC OXIDE SYNTHASE; OXYGEN; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RATS; REACTIVE OXYGEN SPECIES;

EID: 33846031584     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M606129200     Document Type: Article

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