A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5- f ]quinoxaline, 2-Amino-1-methyl-6- phenylimidazo[4,5- b ]pyridine, and their metabolites in human urine

Chemical Research in Toxicology

Volumn 23, Issue 4, 2010, Pages 788-801

  Gu, Dan ^a   McNaughton, Lynn ^b   Lemaster, David ^b   Lake, Brian G ^c   Gooderham, Nigel J ^d   Kadlubar, Fred F ^e   Turesky, Robert J ^a  

^a WADSWORTH CENTER   (United States)

^b UNIVERSITY OF SURREY   (United Kingdom)

^c LFR Molecular Sciences   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; CARCINOGEN; CATION EXCHANGE RESIN; CYTOCHROME P450 1A2; N2 (3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE 2 YL) SULFAMIC ACID; N2 (BETA 1 GLUCOSIDURONYL) 2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; UNCLASSIFIED DRUG;

ARTICLE; CATION EXCHANGE; COOKING; DETOXIFICATION; ENZYME SPECIFICITY; HUMAN; HYDROLYSIS; LIQUID CHROMATOGRAPHY; MEAT; METABOLITE; METABOLOMICS; MONITORING; NONHUMAN; OMNIVORE; TANDEM MASS SPECTROMETRY; URINALYSIS; URINE;

CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP1A2; HUMANS; IMIDAZOLES; MEAT; METABOLOME; QUINOXALINES; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 77951235853     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900436m     Document Type: Article

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