Regioselective differences in C8- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline by human and rat liver microsomes and cytochromes P450 1A2

Chemical Research in Toxicology

Volumn 14, Issue 7, 2001, Pages 901-911

  Turesky, R J ^a,d   Parisod, V ^a   Huynh Ba, T ^a   Langouet S ^b   Guengerich, F P ^c  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

^b UNIVERSITÉ DE RENNES 1   (France)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; CYTOCHROME P450 1A2;

ANIMAL CELL; ARTICLE; CATALYSIS; DETOXIFICATION; ENZYME ACTIVITY; ESCHERICHIA COLI; GENOTOXICITY; HUMAN; HUMAN CELL; LIVER MICROSOME; LIVER MICROSOME METABOLISM; NONHUMAN; OXIDATION; RAT;

EID: 0034933767     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx010035s     Document Type: Article

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