Deconjugation of N-glucuronide conjugated metabolites with hydrazine hydrate - Biomarkers for exposure to the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Food and Chemical Toxicology

Volumn 45, Issue 5, 2007, Pages 863-870

  Frandsen, H ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Biomarkers; Glucuronides; Hydrazine hydrate; PhIP

Indexed keywords

2 AMINO 1 METHYL 6 (4' HYDROXYPHENYL)IMIDAZO[4,5 B]PYRIDINE; 2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; BETA GLUCURONIDASE; BIOLOGICAL MARKER; CARCINOGEN; CYTOCHROME P450; GLUCURONIC ACID; GLUCURONIDE; HYDRAZINE; SULFATASE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCURONIC ACID; XENOBIOTIC AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CHICKEN; CONJUGATION; CONTROLLED STUDY; FOOD CONTAMINATION; GENOTOXICITY; GLUCURONIDATION; HUMAN; HUMAN EXPERIMENT; HYDROLYSIS; HYDROXYLATION; MALE; MASS SPECTROMETRY; METABOLITE; NONHUMAN; NORMAL HUMAN; RABBIT; STANDARD; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL MARKERS; BIOTRANSFORMATION; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOOD CONTAMINATION; GLUCURONATES; GLUCURONIDASE; GLUCURONIDES; HUMANS; HYDRAZINES; IMIDAZOLES; LIVER; MALE; MASS SPECTROMETRY; RABBITS; SPECTROPHOTOMETRY, ULTRAVIOLET;

ORYCTOLAGUS CUNICULUS;

EID: 33947369052     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.11.006     Document Type: Article

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