Detoxification of carcinogenic aromatic and heterocyclic amines by enzymatic reduction of the N-hydroxy derivative

Cancer Letters

Volumn 143, Issue 2, 1999, Pages 167-171

  King, Roberta S ^a   Teitel, Candee H ^a   Shaddock, Joseph G ^a   Casciano, Daniel A ^a   Kadlubar, Fred F ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

A C; Aromatic amine; Detoxification; Heterocyclic amine; IQ; MeIQx; N hydroxy; PhIP

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; 2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; ACYLTRANSFERASE; HETEROCYCLIC AMINE; PHENACETIN O DEETHYLASE; SULFOTRANSFERASE;

ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DETOXIFICATION; DNA ADDUCT; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIVER MICROSOME METABOLISM; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; RAT; TOXICOKINETICS;

ANIMALS; CARCINOGENS; CELLS, CULTURED; DNA ADDUCTS; HUMANS; IMIDAZOLES; MICROSOMES, LIVER; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; QUINOLINES; RATS;

EID: 0032783505     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00119-6     Document Type: Article

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