Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1

Neurobiology of Disease

Volumn 23, Issue 1, 2006, Pages 11-22

  Leinninger, Gina M ^a   Backus, Carey ^a   Sastry, Ann Marie ^b   Yi, Yun Bo ^b   Wang, Chia Wei ^b   Feldman, Eva L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Apoptosis; Bax; Bim; Dorsal root ganglion; Drp1; Fission; Glucose; IGF I; Mitochondria; Neuron

Indexed keywords

BIM PROTEIN; DYNAMIN REGULATED PROTEIN 1; MITOCHONDRIAL PROTEIN; PROTEIN BAX; PROTEIN DERIVATIVE; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INJURY; BRAIN NERVE CELL; CELL COUNT; CELL CULTURE; CELL FUNCTION; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEUROPATHY; EMBRYO; GLUCOSE INTAKE; HYPERGLYCEMIA; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPINAL GANGLION; UPREGULATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CELLS, CULTURED; DIABETIC NEUROPATHIES; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; GTP PHOSPHOHYDROLASES; HYPERGLYCEMIA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEURONS; PROTO-ONCOGENE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33746881744     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2006.01.017     Document Type: Article

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