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Volumn 11, Issue 45, 2005, Pages 7197-7202

Effects of L-carnitine in patients with hepatic encephalopathy

Author keywords

Ammonia; Carnitine; Cirrhosis; Hepatic encephalopathy; Treatment

Indexed keywords

AMMONIA; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARNITINE; DIURETIC AGENT; PLACEBO;

EID: 31544477426     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i45.7197     Document Type: Article
Times cited : (88)

References (32)
  • 1
    • 0025979046 scopus 로고
    • Cerebral ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy
    • Lockwood AH, Yap EW, Wong WH Cerebral ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy. J Cereb Blood Flow Metab 1991; 11: 337-341
    • (1991) J Cereb Blood Flow Metab , vol.11 , pp. 337-341
    • Lockwood, A.H.1    Yap, E.W.2    Wong, W.H.3
  • 2
    • 0033915068 scopus 로고    scopus 로고
    • Brain oedema and portal-systemic encephalopathy
    • Blei AT. Brain oedema and portal-systemic encephalopathy. Liver Transpl. 2000; 6: S14-20
    • (2000) Liver Transpl. , vol.6
    • Blei, A.T.1
  • 3
    • 0021279657 scopus 로고
    • Prevention of ammonia toxicity by L-carnitine: Metabolic changes in brain
    • O'Connor JE, Costell M, Grisolia S. Prevention of ammonia toxicity by L-carnitine: metabolic changes in brain. Neurochem Res 1984; 9: 563-570
    • (1984) Neurochem Res , vol.9 , pp. 563-570
    • O'Connor, J.E.1    Costell, M.2    Grisolia, S.3
  • 4
    • 0031050889 scopus 로고    scopus 로고
    • Protective effect of L-carnitine in ammonia-precipitated encephalopathy in the portacaval shunted rat
    • Therrien G, Rose C, Butterworth J, Butterworth RF. Protective effect of L-carnitine in ammonia-precipitated encephalopathy in the portacaval shunted rat. Hepatology 1997; 25: 551-556
    • (1997) Hepatology , vol.25 , pp. 551-556
    • Therrien, G.1    Rose, C.2    Butterworth, J.3    Butterworth, R.F.4
  • 5
    • 0026332787 scopus 로고
    • Suppression of neurotoxicity of ammonia by L-carnitine
    • Matsuoka M, Igisu H, Kohriyama K, Inoue N. Suppression of neurotoxicity of ammonia by L-carnitine. Brain Res. 1991; 567: 328-331
    • (1991) Brain Res. , vol.567 , pp. 328-331
    • Matsuoka, M.1    Igisu, H.2    Kohriyama, K.3    Inoue, N.4
  • 7
    • 0002632388 scopus 로고    scopus 로고
    • The role of carnitine in cell metabolism
    • De Simone C, Famularo G. (eds). Springer-Verlag, Heidelberg
    • Bremer J. The role of carnitine in cell metabolism. In: De Simone C, Famularo G. (eds). Carnitine Today. Springer-Verlag, Heidelberg, 1997; pp. 1-37
    • (1997) Carnitine Today , pp. 1-37
    • Bremer, J.1
  • 8
    • 0023789866 scopus 로고
    • Ammonia and glutamine metabolism in human liver slices: New aspects on the pathogenesis of hyperammonaemia in chronic liver disease
    • Kaiser S, Gerok W, Haussinger D. Ammonia and glutamine metabolism in human liver slices: new aspects on the pathogenesis of hyperammonaemia in chronic liver disease. Eur J Clin Invest 1988; 18: 535-542
    • (1988) Eur J Clin Invest , vol.18 , pp. 535-542
    • Kaiser, S.1    Gerok, W.2    Haussinger, D.3
  • 9
    • 0028021247 scopus 로고
    • Changes in distribution and activity of glutamine synthetase in carbon tetrachloride-induced cirrhosis in the rat: Potential role in hyperammonemia
    • Gebhardt R, Reichen J. Changes in distribution and activity of glutamine synthetase in carbon tetrachloride-induced cirrhosis in the rat: potential role in hyperammonemia. Hepatology 1994; 20: 684-691
    • (1994) Hepatology , vol.20 , pp. 684-691
    • Gebhardt, R.1    Reichen, J.2
  • 11
    • 0003818083 scopus 로고
    • The hepatic coma syndromes and lactulose
    • Baltimore: Williams and Wilkins
    • Conn HO, Liebertahl MM. The hepatic coma syndromes and lactulose. Baltimore: Williams and Wilkins, 1979: 1-121
    • (1979) , pp. 1-121
    • Conn, H.O.1    Liebertahl, M.M.2
  • 12
    • 0017645699 scopus 로고
    • Trailmaking and number connection tests in the assessment of mental state in portal systemic encephalopathy
    • Conn HO. Trailmaking and number connection tests in the assessment of mental state in portal systemic encephalopathy. Am J Dig Dis 1977; 22: 541-550
    • (1977) Am J Dig Dis , vol.22 , pp. 541-550
    • Conn, H.O.1
  • 13
    • 0017889855 scopus 로고
    • Neomycin-sorbitol and lactulose in the treatment of acute portal-systemic encephalopathy. A controlled, double-blind clinical trial
    • Atterbury CE, Maddrey WC, Conn HO. Neomycin-sorbitol and lactulose in the treatment of acute portal-systemic encephalopathy. A controlled, double-blind clinical trial. Am J Dig Dis 1978; 23: 398-406
    • (1978) Am J Dig Dis , vol.23 , pp. 398-406
    • Atterbury, C.E.1    Maddrey, W.C.2    Conn, H.O.3
  • 16
    • 0015674163 scopus 로고
    • Direct determination of plasma ammonia without deproteinization. An improved enzymic determination of ammonia, II
    • (author's transl)
    • Da Fonseca-Wollheim F. Direct determination of plasma ammonia without deproteinization. An improved enzymic determination of ammonia, II (author's transl). Z Klin Chem Klin Biochem 1973; 11: 426-431
    • (1973) Z Klin Chem Klin Biochem , vol.11 , pp. 426-431
    • Da Fonseca-Wollheim, F.1
  • 18
    • 0025979046 scopus 로고
    • Cerebral ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy
    • Lockwood AH, Yap EW, Wong WH. Cerebral ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy. J Cereb Blood Flow Metab 1991; 11: 337-341
    • (1991) J Cereb Blood Flow Metab , vol.11 , pp. 337-341
    • Lockwood, A.H.1    Yap, E.W.2    Wong, W.H.3
  • 19
    • 0023200903 scopus 로고
    • Effect of L-carnitine on ketone bodies, redox state and free amino acids in the liver of hyperammonemic mice
    • O'Connor JE, Costell M, Miguez MP, Portoles M, Grisolia S. Effect of L-carnitine on ketone bodies, redox state and free amino acids in the liver of hyperammonemic mice. Biochem Pharmacol 1987; 36: 3169-3173
    • (1987) Biochem Pharmacol , vol.36 , pp. 3169-3173
    • O'Connor, J.E.1    Costell, M.2    Miguez, M.P.3    Portoles, M.4    Grisolia, S.5
  • 20
    • 0025289407 scopus 로고
    • Plasma and urinary levels of carnitine in different experimental models of hyperammonemia and the effect of sodium benzoate treatment
    • Michalak A, Qureshi IA. Plasma and urinary levels of carnitine in different experimental models of hyperammonemia and the effect of sodium benzoate treatment. Biochem Med Metab Biol 1990; 43: 163-174
    • (1990) Biochem Med Metab Biol , vol.43 , pp. 163-174
    • Michalak, A.1    Qureshi, I.A.2
  • 21
    • 0027203913 scopus 로고
    • Effect of L-carnitine on cerebral and hepatic energy metabolites in congenitally hyperammonemic sparse-fur mice and its role during benzoate therapy
    • Ratnakumari L, Qureshi IA, Butterworth RF. Effect of L-carnitine on cerebral and hepatic energy metabolites in congenitally hyperammonemic sparse-fur mice and its role during benzoate therapy Metabolism 1993; 42: 1039-1046
    • (1993) Metabolism , vol.42 , pp. 1039-1046
    • Ratnakumari, L.1    Qureshi, I.A.2    Butterworth, R.F.3
  • 22
    • 0030902779 scopus 로고    scopus 로고
    • Ammonia and GABA-ergic neurotransmission: Interrelated factors in the pathogenesis of hepatic encephalopathy
    • Basile AS, Jones EA. Ammonia and GABA-ergic neurotransmission: interrelated factors in the pathogenesis of hepatic encephalopathy. Hepatology 1997; 25: 1303-1305
    • (1997) Hepatology , vol.25 , pp. 1303-1305
    • Basile, A.S.1    Jones, E.A.2
  • 23
    • 0030448092 scopus 로고    scopus 로고
    • Astrocytic-ammonia interactions in hepatic encephalopathy
    • Norenberg MD. Astrocytic-ammonia interactions in hepatic encephalopathy. Semin Liver Dis 1996; 16: 245-253
    • (1996) Semin Liver Dis , vol.16 , pp. 245-253
    • Norenberg, M.D.1
  • 25
    • 0034018410 scopus 로고    scopus 로고
    • The role of carnitine supplementation during valproic acid therapy
    • Raskind JY, El-Chaar GM. The role of carnitine supplementation during valproic acid therapy. Ann Pharmacother 2000; 34: 630-638
    • (2000) Ann Pharmacother , vol.34 , pp. 630-638
    • Raskind, J.Y.1    El-Chaar, G.M.2
  • 26
    • 0019941501 scopus 로고
    • Carnitine deficiency and hyperammonemia associated with valproic acid therapy
    • Ohtani Y, Endo F, Matsuda I. Carnitine deficiency and hyperammonemia associated with valproic acid therapy. J Pediatr 1982; 101: 782-785
    • (1982) J Pediatr , vol.101 , pp. 782-785
    • Ohtani, Y.1    Endo, F.2    Matsuda, I.3
  • 27
    • 0023222128 scopus 로고
    • Hepatotoxicity in rat following administration of valproic acid: Effect of L-carnitine supplementation
    • Sugimoto T, Araki A, Nishida N, Sakane Y, Woo M, Takeuchi T, Kobayashi Y. Hepatotoxicity in rat following administration of valproic acid: effect of L-carnitine supplementation. Epilepsia. 1987; 28: 373-377
    • (1987) Epilepsia , vol.28 , pp. 373-377
    • Sugimoto, T.1    Araki, A.2    Nishida, N.3    Sakane, Y.4    Woo, M.5    Takeuchi, T.6    Kobayashi, Y.7
  • 28
    • 0003436928 scopus 로고
    • The Halstead-Reitan. Neuropsychological test battery: Theory and clinical interpretation
    • Tucson, AZ: Neuropsychology Press
    • Reitan RM, Wolfson D. The Halstead-Reitan. Neuropsychological test battery: theory and clinical interpretation. Tucson, AZ: Neuropsychology Press; 1993
    • (1993)
    • Reitan, R.M.1    Wolfson, D.2
  • 29
    • 0024453030 scopus 로고
    • Effect of orally administered L-carnitine on blood ammonia and L-carnitine concentrations in portacaval-shunted rats
    • Hearn TJ, Coleman AE, Lai JC, Griffith OW, Cooper AJ. Effect of orally administered L-carnitine on blood ammonia and L-carnitine concentrations in portacaval-shunted rats. Hepatology 1989; 10: 822-828
    • (1989) Hepatology , vol.10 , pp. 822-828
    • Hearn, T.J.1    Coleman, A.E.2    Lai, J.C.3    Griffith, O.W.4    Cooper, A.J.5
  • 30
    • 0026339530 scopus 로고
    • Increased cerebrospinal fluid lactate reflects deterioration of neurological status in experimental portal-systemic encephalopathy
    • Therrien G, Giguere JF, Butterworth RF. Increased cerebrospinal fluid lactate reflects deterioration of neurological status in experimental portal-systemic encephalopathy. Metab Brain Dis 1991; 6: 231-238
    • (1991) Metab Brain Dis , vol.6 , pp. 231-238
    • Therrien, G.1    Giguere, J.F.2    Butterworth, R.F.3
  • 31
    • 0021851525 scopus 로고
    • Acyl-CoA esters of xenobiotic carboxylic acids as biochemically active intermediates
    • Sherratt HS. Acyl-CoA esters of xenobiotic carboxylic acids as biochemically active intermediates. Biochem Soc Trans 1985; 13: 856-858
    • (1985) Biochem Soc Trans , vol.13 , pp. 856-858
    • Sherratt, H.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.