-
1
-
-
0028124428
-
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
-
Rothe M, Wong S C, Henzel W J, et al. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell, 1994, 78: 681-692.
-
(1994)
Cell
, vol.78
, pp. 681-692
-
-
Rothe, M.1
Wong, S.C.2
Henzel, W.J.3
-
2
-
-
0027943499
-
A novel RING finger protein interacts with the cytoplasmic domain of CD40
-
Hu H M, O'Rourke K, Boguski M S, et al. A novel RING finger protein interacts with the cytoplasmic domain of CD40. J Biol Chem, 1994, 269: 30069-30072.
-
(1994)
J Biol Chem
, vol.269
, pp. 30069-30072
-
-
Hu, H.M.1
O'Rourke, K.2
Boguski, M.S.3
-
3
-
-
0028936733
-
Involvement of CRAF1, a relative of TRAF, in CD40 signaling
-
Cheng G, Cleary A M, Ye Z S, et al. Involvement of CRAF1, a relative of TRAF, in CD40 signaling. Science, 1995, 267: 1494-1498.
-
(1995)
Science
, vol.267
, pp. 1494-1498
-
-
Cheng, G.1
Cleary, A.M.2
Ye, Z.S.3
-
4
-
-
0028809176
-
A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40
-
Sato T, Irie S, Reed J C. A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40. FEBS Lett, 1995, 358: 113-118.
-
(1995)
FEBS Lett
, vol.358
, pp. 113-118
-
-
Sato, T.1
Irie, S.2
Reed, J.C.3
-
5
-
-
0035475338
-
Tumor necrosis factor receptor-associated factors (TRAFs)
-
Bradley J R, Pober J S. Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene, 2001, 20: 6482-6491.
-
(2001)
Oncogene
, vol.20
, pp. 6482-6491
-
-
Bradley, J.R.1
Pober, J.S.2
-
6
-
-
0037084504
-
All TRAFs are not created equal: Common and distinct molecular mechanisms of TRAF-mediated signal transduction
-
Chung J Y, Park Y C, Ye H, et al. All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J Cell Sc, 2002, 115: 679-688.
-
(2002)
J Cell Sc
, vol.115
, pp. 679-688
-
-
Chung, J.Y.1
Park, Y.C.2
Ye, H.3
-
8
-
-
5044223172
-
The multifaceted roles of TRAFS in the regulation of B-cell function
-
Bishop G A. The multifaceted roles of TRAFS in the regulation of B-cell function. Na. Rev Immunol, 2004, 4: 775-786.
-
(2004)
Na. Rev Immunol
, vol.4
, pp. 775-786
-
-
Bishop, G.A.1
-
9
-
-
0001033803
-
Structural basis for self-association and receptor recognition of human TRAF2
-
Park Y C, Burkitt V, Villa A R, et al. Structural basis for self-association and receptor recognition of human TRAF2. Nature, 1999, 398: 533-538.
-
(1999)
Nature
, vol.398
, pp. 533-538
-
-
Park, Y.C.1
Burkitt, V.2
Villa, A.R.3
-
10
-
-
0031962348
-
4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB
-
Arch R H, Thompson C B. 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB. Mol Cell Biol, 1998, 18: 558-565.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 558-565
-
-
Arch, R.H.1
Thompson, C.B.2
-
11
-
-
0033587691
-
Crystallographic analysis of CD40 recognition and signaling by human TRAF2
-
McWhirter S M, Pullen S S, Holton J M, et al. Crystallographic analysis of CD40 recognition and signaling by human TRAF2. Proc Natl Acad Sci USA, 1999, 96: 8408-8413.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8408-8413
-
-
McWhirter, S.M.1
Pullen, S.S.2
Holton, J.M.3
-
12
-
-
0036024518
-
Crystallization and preliminary X-ray analysis of the TRAF domain of TRAF3
-
Ni C Z, Welsh K, Zheng J, et al. Crystallization and preliminary X-ray analysis of the TRAF domain of TRAF3. Acta Crystallogr D, 2002, 58: 1340-1342.
-
(2002)
Acta Crystallogr D
, vol.58
, pp. 1340-1342
-
-
Ni, C.Z.1
Welsh, K.2
Zheng, J.3
-
13
-
-
57449104909
-
IRF7 activation by Epstein-Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3
-
Song Y J, Izumi K M, Shinners N P, et al. IRF7 activation by Epstein-Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3. Proc Natl Acad Sci USA, 2008, 105: 18448-18453.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18448-18453
-
-
Song, Y.J.1
Izumi, K.M.2
Shinners, N.P.3
-
14
-
-
18344384218
-
Downstream regulator TANK binds to the CD40 recognition site on TRAF3
-
Li C, Ni C Z, Havert M L, et al. Downstream regulator TANK binds to the CD40 recognition site on TRAF3. Structure, 2002, 10: 403-411.
-
(2002)
Structure
, vol.10
, pp. 403-411
-
-
Li, C.1
Ni, C.Z.2
Havert, M.L.3
-
15
-
-
10344226678
-
Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: Implications for intracellular signaling regulation
-
Ni C Z, Oganesyan G, Welsh K, et al. Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation. J Immunol, 2004, 173: 7394-7400.
-
(2004)
J Immunol
, vol.173
, pp. 7394-7400
-
-
Ni, C.Z.1
Oganesyan, G.2
Welsh, K.3
-
16
-
-
36249002186
-
2007 Molecular identification and expression analysis of tumor necrosis factor receptor-associated factor 2 in grass carp Ctenopharyngodon idella
-
Xu Z, Nie P, Sun B, et al. 2007 Molecular identification and expression analysis of tumor necrosis factor receptor-associated factor 2 in grass carp Ctenopharyngodon idella. Acta Biochim Biophys Sin, 2007, 39: 857-868.
-
(2007)
Acta Biochim Biophys Sin
, vol.39
, pp. 857-868
-
-
Xu, Z.1
Nie, P.2
Sun, B.3
-
17
-
-
18444390259
-
Distinct molecular mechanism for initiating TRAF6 signalling
-
Ye H, Arron J R, Lamothe B, et al. Distinct molecular mechanism for initiating TRAF6 signalling. Nature, 2002, 418: 443-447.
-
(2002)
Nature
, vol.418
, pp. 443-447
-
-
Ye, H.1
Arron, J.R.2
Lamothe, B.3
-
18
-
-
67349242723
-
E2 interaction and dimerization in the crystal structure of TRAF6
-
Yin Q, Lin S C, Lamothe B, et al. E2 interaction and dimerization in the crystal structure of TRAF6. Nat Struct Mol Biol, 2009, 16: 658-697.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 658-697
-
-
Yin, Q.1
Lin, S.C.2
Lamothe, B.3
-
19
-
-
0034644474
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng L, Wang C, Spencer E, et al. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell, 2000, 103: 351-361.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
-
20
-
-
0038150358
-
Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2)
-
Shi C S, Kehrl J H. Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2). J Biol Chem, 2003, 278: 15429-15434.
-
(2003)
J Biol Chem
, vol.278
, pp. 15429-15434
-
-
Shi, C.S.1
Kehrl, J.H.2
-
21
-
-
0242413228
-
Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling
-
Hostager B S, Haxhinasto S A, Rowland S L, et al. Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling. J Biol Chem, 2003, 278: 45382-45390.
-
(2003)
J Biol Chem
, vol.278
, pp. 45382-45390
-
-
Hostager, B.S.1
Haxhinasto, S.A.2
Rowland, S.L.3
-
22
-
-
33645955898
-
Structure and interactions of the helical and U-box domains of CHIP, the C terminus of HSP70 interacting protein
-
Xu Z, Devlin K I, Ford M G, et al. Structure and interactions of the helical and U-box domains of CHIP, the C terminus of HSP70 interacting protein. Biochemistry, 2006, 45: 4749-4759.
-
(2006)
Biochemistry
, vol.45
, pp. 4749-4759
-
-
Xu, Z.1
Devlin, K.I.2
Ford, M.G.3
-
23
-
-
27944495299
-
Chaperoned ubiquitylation-crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex
-
Zhang M, Windheim M, Roe S M, et al. Chaperoned ubiquitylation-crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex. Mol Cell, 2005, 20: 525-538.
-
(2005)
Mol Cell
, vol.20
, pp. 525-538
-
-
Zhang, M.1
Windheim, M.2
Roe, S.M.3
-
24
-
-
0037205442
-
Regulation of TRAF2 signaling by self-induced degradation
-
Brown K D, Hostager B S, Bishop G A. Regulation of TRAF2 signaling by self-induced degradation. J Biol Chem, 2002, 277: 19433-19438.
-
(2002)
J Biol Chem
, vol.277
, pp. 19433-19438
-
-
Brown, K.D.1
Hostager, B.S.2
Bishop, G.A.3
-
25
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden M S, Ghosh S. Shared principles in NF-kappaB signaling. Cell, 2008, 132: 344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
26
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G, Goeddel D V. TNF-R1 signaling: a beautiful pathway. Science, 2002, 296: 1634-1635.
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
27
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell, 2003, 114, 181-190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
28
-
-
33646034316
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea C K, Deng L, Xia Z P, et al. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell, 2006, 22: 245-257.
-
(2006)
Mol Cell
, vol.22
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
-
29
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
-
Wu C J, Conze D B, Li T, et al. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol, 2006, 8: 398-406.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
-
30
-
-
4344712350
-
TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains
-
Kanayama A, Seth R B, Sun L, et al. TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. Mol Cell, 2004, 15: 535-548.
-
(2004)
Mol Cell
, vol.15
, pp. 535-548
-
-
Kanayama, A.1
Seth, R.B.2
Sun, L.3
-
31
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
-
Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol, 2000, 18: 621-663.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
32
-
-
4043136609
-
The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2
-
Lee T H, Shank J, Cusson N, et al. The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2. J Biol Chem, 2004: 279, 33185-33191.
-
(2004)
J Biol Chem
, vol.279
, pp. 33185-33191
-
-
Lee, T.H.1
Shank, J.2
Cusson, N.3
-
33
-
-
44949240664
-
CIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
Bertrand M J, Milutinovic S, Dickson K M, et al. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell, 2008, 30: 689-700.
-
(2008)
Mol Cell
, vol.30
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
-
34
-
-
72149117664
-
TRAF2 must bind to cIAPs for TNF to efficiently activate NF-{kappa}B and to prevent TNF-induced apoptosis
-
Vince J E, Pantaki D, Feltham R, et al. TRAF2 must bind to cIAPs for TNF to efficiently activate NF-{kappa}B and to prevent TNF-induced apoptosis. J Biol Chem, 2009, 284: 35906-35915.
-
(2009)
J Biol Chem
, vol.284
, pp. 35906-35915
-
-
Vince, J.E.1
Pantaki, D.2
Feltham, R.3
-
35
-
-
0033485542
-
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase
-
Pomerantz J L, Baltimore D. NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase. Embo J, 2009, 18: 6694-6704.
-
(2009)
Embo J
, vol.18
, pp. 6694-6704
-
-
Pomerantz, J.L.1
Baltimore, D.2
-
36
-
-
0034665047
-
Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription
-
Bonnard M, Mirtsos C, Suzuki S, et al. Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription. Embo J, 2000, 19: 4976-4985.
-
(2000)
Embo J
, vol.19
, pp. 4976-4985
-
-
Bonnard, M.1
Mirtsos, C.2
Suzuki, S.3
-
37
-
-
5644302162
-
Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase
-
Ramakrishnan P, Wang W, Wallach D. Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. Immunity, 2004, 21: 477-489.
-
(2004)
Immunity
, vol.21
, pp. 477-489
-
-
Ramakrishnan, P.1
Wang, W.2
Wallach, D.3
-
38
-
-
5044223172
-
The multifaceted roles of TRAFs in the regulation of B-cell function
-
Bishop G A. The multifaceted roles of TRAFs in the regulation of B-cell function. Nat Rev Immunol, 2004, 4: 775-786.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 775-786
-
-
Bishop, G.A.1
-
39
-
-
0031573208
-
Characterization of CD40 signaling determinants regulating nuclear factor-kappa B activation in B lymphocytes
-
Hsing Y, Hostager B S, Bishop G A. Characterization of CD40 signaling determinants regulating nuclear factor-kappa B activation in B lymphocytes. J Immunol, 1997, 159: 4898-4906.
-
(1997)
J Immunol
, vol.159
, pp. 4898-4906
-
-
Hsing, Y.1
Hostager, B.S.2
Bishop, G.A.3
-
40
-
-
0033553392
-
CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFs
-
Pullen S S, Dang T T, Crute J J, et al. CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFs. J Biol Chem, 1999, 274: 14246-14254.
-
(1999)
J Biol Chem
, vol.274
, pp. 14246-14254
-
-
Pullen, S.S.1
Dang, T.T.2
Crute, J.J.3
-
41
-
-
36049033394
-
Signaling to NF-kappaB by Toll-like receptors
-
Kawai T, Akira S. Signaling to NF-kappaB by Toll-like receptors. Trends Mol Med, 2007, 13: 460-469.
-
(2007)
Trends Mol Med
, vol.13
, pp. 460-469
-
-
Kawai, T.1
Akira, S.2
-
42
-
-
0042405132
-
Recognition of microbial infection by Toll-like receptors
-
Kopp E, Medzhitov R. Recognition of microbial infection by Toll-like receptors. Curr Opin Immunol, 2003, 15: 396-401.
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 396-401
-
-
Kopp, E.1
Medzhitov, R.2
-
43
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao Z, Xiong J, Takeuchi M, et al. TRAF6 is a signal transducer for interleukin-1. Nature, 1996, 383: 443-446.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
-
44
-
-
0038526352
-
Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling
-
Takatsuna H, Kato H, Gohda J, et al. Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling. J Biol Chem, 2003, 278, 12144-12150.
-
(2003)
J Biol Chem
, vol.278
, pp. 12144-12150
-
-
Takatsuna, H.1
Kato, H.2
Gohda, J.3
-
45
-
-
43249120917
-
Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation
-
Conze D B, Wu C J, Thomas J A, et al. Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation. Mol Cell Biol, 2008, 28: 3538-3547.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 3538-3547
-
-
Conze, D.B.1
Wu, C.J.2
Thomas, J.A.3
-
46
-
-
0035834672
-
IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B
-
Qian Y, Commane M, Ninomiya-Tsuji J, et al. IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B. J Biol Chem, 2001, 276: 41661-41667.
-
(2001)
J Biol Chem
, vol.276
, pp. 41661-41667
-
-
Qian, Y.1
Commane, M.2
Ninomiya-Tsuji, J.3
-
47
-
-
0033634977
-
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
-
Takaesu G, Kishida S, Hiyama A, et al. TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol Cell, 2000, 5: 649-658.
-
(2000)
Mol Cell
, vol.5
, pp. 649-658
-
-
Takaesu, G.1
Kishida, S.2
Hiyama, A.3
-
48
-
-
25844459154
-
NF-kappaB: Linking inflammation and immunity to cancer development and progression
-
Karin M, Greten F R. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol, 2005, 5: 749-759.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
49
-
-
31344463886
-
Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
-
Wang Y, Tang Y, Teng L, et al. Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat Immunol, 2006, 7: 139-147.
-
(2006)
Nat Immunol
, vol.7
, pp. 139-147
-
-
Wang, Y.1
Tang, Y.2
Teng, L.3
-
50
-
-
0031985287
-
Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses
-
Caamaño J H, Rizzo C A, Durham S K, et al. Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses. J Exp Med, 1998, 187: 185-196.
-
(1998)
J Exp Med
, vol.187
, pp. 185-196
-
-
Caamaño, J.H.1
Rizzo, C.A.2
Durham, S.K.3
-
51
-
-
0031964855
-
Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture
-
Franzoso G, Carlson L, Poljak L, et al. Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture. J Exp Med, 1998, 187: 147-159.
-
(1998)
J Exp Med
, vol.187
, pp. 147-159
-
-
Franzoso, G.1
Carlson, L.2
Poljak, L.3
-
52
-
-
0032127301
-
The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues
-
Futterer A, Mink K, Luz A, et al. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity, 1998, 9: 59-70.
-
(1998)
Immunity
, vol.9
, pp. 59-70
-
-
Futterer, A.1
Mink, K.2
Luz, A.3
-
53
-
-
0032127288
-
Lymph node genesis is induced by signaling through the lymphotoxin beta receptor
-
Rennert P D, James D, Mackay F, et al. Lymph node genesis is induced by signaling through the lymphotoxin beta receptor. Immunity, 1998, 9: 71-79.
-
(1998)
Immunity
, vol.9
, pp. 71-79
-
-
Rennert, P.D.1
James, D.2
Mackay, F.3
-
54
-
-
0037413709
-
RelB is required for Peyer's patch development: Differential regulation of p52-RelB by lymphotoxin and TNF
-
Yilmaz Z B, Weih D S, Sivakumar V, et al. RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF. EMBO J, 2003, 22: 121-130.
-
(2003)
EMBO J
, vol.22
, pp. 121-130
-
-
Yilmaz, Z.B.1
Weih, D.S.2
Sivakumar, V.3
-
55
-
-
0032930861
-
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase
-
Shinkura R, Kitada K, Matsuda F, et al. Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nat Genet, 1999, 22: 74-77.
-
(1999)
Nat Genet
, vol.22
, pp. 74-77
-
-
Shinkura, R.1
Kitada, K.2
Matsuda, F.3
-
56
-
-
0035896422
-
Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice
-
Yin L, Wu L, Wesche H, Arthur C D, et al. Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. Science, 2001, 291: 2162-2165.
-
(2001)
Science
, vol.291
, pp. 2162-2165
-
-
Yin, L.1
Wu, L.2
Wesche, H.3
Arthur, C.D.4
-
57
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
-
Annunziata C M, Davis R E, Demchenko Y, et al. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell, 2007, 12: 115-130.
-
(2007)
Cancer Cell
, vol.12
, pp. 115-130
-
-
Annunziata, C.M.1
Davis, R.E.2
Demchenko, Y.3
-
58
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma
-
Keats J J, Fonseca R, Chesi M, et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell, 2007, 12: 131-144.
-
(2007)
Cancer Cell
, vol.12
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
-
59
-
-
56349164239
-
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
-
Zarnegar B J, Wang Y, Mahoney D J, et al. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol, 2008, 9: 1371-1378.
-
(2008)
Nat Immunol
, vol.9
, pp. 1371-1378
-
-
Zarnegar, B.J.1
Wang, Y.2
Mahoney, D.J.3
-
60
-
-
2942731516
-
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation
-
Liao G, Zhang M, Harhaj E W, et al. Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation. J Biol Chem, 2004, 279: 26243-26250.
-
(2004)
J Biol Chem
, vol.279
, pp. 26243-26250
-
-
Liao, G.1
Zhang, M.2
Harhaj, E.W.3
-
61
-
-
56349164232
-
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling
-
Vallabhapurapu S, Matsuzawa A, Zhang W, et al. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat Immunol, 2008, 9: 1364-13670.
-
(2008)
Nat Immunol
, vol.9
, pp. 1364-13670
-
-
Vallabhapurapu, S.1
Matsuzawa, A.2
Zhang, W.3
-
62
-
-
33750494135
-
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
-
He J Q, Zarnegar B, Oganesyan G, et al. Rescue of TRAF3-null mice by p100 NF-kappa B deficiency. J Exp Med, 2006, 203: 2413-2418.
-
(2006)
J Exp Med
, vol.203
, pp. 2413-2418
-
-
He, J.Q.1
Zarnegar, B.2
Oganesyan, G.3
-
63
-
-
36048999753
-
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
-
Varfolomeev E, Blankenship J W, Wayson S M, et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell, 2007, 131: 669-681.
-
(2007)
Cell
, vol.131
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
-
64
-
-
36148954336
-
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
-
Vince J E, Wong W W, Khan N, et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell, 2007, 131: 682-693.
-
(2007)
Cell
, vol.131
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.2
Khan, N.3
-
65
-
-
58049202272
-
Innate immunity to virus infection
-
Takeuchi O, Akira S. Innate immunity to virus infection. Immunol Rev, 2009, 227: 75-86.
-
(2009)
Immunol Rev
, vol.227
, pp. 75-86
-
-
Takeuchi, O.1
Akira, S.2
-
66
-
-
5444274514
-
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
-
Kawai T, Sato S, Ishii K J, et al. Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol, 2004, 5: 1061-1068.
-
(2004)
Nat Immunol
, vol.5
, pp. 1061-1068
-
-
Kawai, T.1
Sato, S.2
Ishii, K.J.3
-
67
-
-
33645841633
-
IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9
-
Hoshino K, Sugiyama T, Matsumoto M, et al. IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9. Nature, 2006, 440: 949-953.
-
(2006)
Nature
, vol.440
, pp. 949-953
-
-
Hoshino, K.1
Sugiyama, T.2
Matsumoto, M.3
-
68
-
-
20244388983
-
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction
-
Uematsu S, Sato S, Yamamoto M, et al. Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction. J Exp Med, 2005, 201: 915-923.
-
(2005)
J Exp Med
, vol.201
, pp. 915-923
-
-
Uematsu, S.1
Sato, S.2
Yamamoto, M.3
-
69
-
-
0038393016
-
V IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
-
Katherine A F, Sarah M M, Kerrie L F, et al. v IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol, 2003, 4: 491-496.
-
(2003)
Nat Immunol
, vol.4
, pp. 491-496
-
-
Katherine, A.F.1
Sarah, M.M.2
Kerrie, L.F.3
-
70
-
-
4344566281
-
The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection
-
Hemmi H, Takeuchi O, Sato S, et al. The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection. J Exp Med, 2004, 199: 1641-1650.
-
(2004)
J Exp Med
, vol.199
, pp. 1641-1650
-
-
Hemmi, H.1
Takeuchi, O.2
Sato, S.3
-
71
-
-
3042647375
-
Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection
-
Perry A K, Chow E K, Goodnough J B, et al. Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection. J Exp Med, 2004, 199: 1651-1658.
-
(2004)
J Exp Med
, vol.199
, pp. 1651-1658
-
-
Perry, A.K.1
Chow, E.K.2
Goodnough, J.B.3
-
72
-
-
33748475531
-
Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors
-
Honda K, Takaoka A, Taniguchi T. Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity, 2006, 25: 349-360.
-
(2006)
Immunity
, vol.25
, pp. 349-360
-
-
Honda, K.1
Takaoka, A.2
Taniguchi, T.3
-
73
-
-
17144404177
-
IRF-7 is the master regulator of type-I interferon-dependent immune responses
-
Honda K, Yanai H, Negishi H, et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature, 2005, 434: 772-777.
-
(2005)
Nature
, vol.434
, pp. 772-777
-
-
Honda, K.1
Yanai, H.2
Negishi, H.3
-
74
-
-
30544447047
-
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
-
Oganesyan G, Saha S K, Guo B, et al. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature, 2005, 439: 208-211.
-
(2005)
Nature
, vol.439
, pp. 208-211
-
-
Oganesyan, G.1
Saha, S.K.2
Guo, B.3
-
75
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai T, Takahashi K, Sato S, et al. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol, 2005, 6: 981-988.
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
-
76
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature, 2005, 437: 1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
-
77
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth R B, Sun L, Ea C K, et al. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell, 2005, 122: 669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
-
78
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-beta signaling
-
Xu L G, Wang Y Y, Han K J, et al. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol Cell, 2005, 19: 727-740.
-
(2005)
Mol Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
-
79
-
-
33746479050
-
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif
-
Saha S K, Pietras E M, He J Q, et al. Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif. EMBO J, 2006, 25: 3257-3263.
-
(2006)
EMBO J
, vol.25
, pp. 3257-3263
-
-
Saha, S.K.1
Pietras, E.M.2
He, J.Q.3
-
80
-
-
36448943427
-
DUBA: A deubiquitinase that regulates type I interferon production
-
Kayagaki N, Phung Q, Chan S, et al. DUBA: a deubiquitinase that regulates type I interferon production. Science, 2007, 318: 1628-1632.
-
(2007)
Science
, vol.318
, pp. 1628-1632
-
-
Kayagaki, N.1
Phung, Q.2
Chan, S.3
-
81
-
-
67649229630
-
The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon
-
Wang C, Chen T, Zhang J, et al. The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. Nat Immunol, 2009, 10: 744-752.
-
(2009)
Nat Immunol
, vol.10
, pp. 744-752
-
-
Wang, C.1
Chen, T.2
Zhang, J.3
|