Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2)

Journal of Biological Chemistry

Volumn 278, Issue 17, 2003, Pages 15429-15434

  Shi, Chong Shan ^b   Kehrl, John H ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ENZYME INHIBITION; ENZYMES; OLIGOMERS;

TUMOR NECROSIS FACTOR (TNF);

TUMORS;

DIMER; LYSINE; PHOSPHOTRANSFERASE; PROTEIN UEV1A; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ASSOCIATED FACTOR 2; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; GERMINAL CENTER; HUMAN; HUMAN CELL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ENZYME ACTIVATION; HUMANS; LIGASES; MAP KINASE KINASE KINASE 5; MAP KINASE KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 2; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES;

EID: 0038150358     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211796200     Document Type: Article

References (21)

1. Kyriakis, J. M. (2000) in Protein Kinase Functions (Woodgett, J., ed) pp. 40-156, Oxford University Press, Oxford, UK
2. Kyriakis, J. M., and Avruch, J. (2001) Physiol. Rev. 81, 807-869
3. Locksley, R. M., Killeen, N., and Lenardo, M. J. (2001) Cell 104, 487-501
4. Liu, Z. G., Hsu, H., Goeddel, D. V., and Karin, M. (1996) Cell 87, 565-576
5. Natoli, G., Costanzo, A., Ianni, A., Templeton, D. J., Woodgett, J. R., Balsano, C., and Levrero, M. (1997) Science 275, 200-203
6. Baud, V., Liu, Z.-G., Bennett, B., Suzuki, N., Xia, Y., and Karin, M. (1999) Genes Dev. 13, 1297-1308
7. Xia, Y., Makris, C., Su, B., Li, E., Yang, J., Nemerow, G., and Davis, R. J. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5243-5248
8. Kyriakis, J. M. (1999) J. Biol. Chem. 274, 5259-5262
9. Shi, C. S., and Kehrl, J. H. (1997) J. Biol. Chem. 272, 32102-32107
10. Yuasa, T., Ohno, S., Kehrl, J. H., and Kyriakis, J. M. (1998) J. Biol. Chem. 273, 22681-22692
11. Shi, C. S., Leonardi, A., Kyriakis, J., Siebenlist, U., and Kehrl, J. H. (1999) J. Immunol. 163, 3279-3285
12. Chadee, D. N., Yuasa, T., and Kyriakis, J. M. (2002) Mol. Cell. Biol. 22, 737-749
13. Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C., and Chen, Z. J. (2000) Cell 103, 351-361
14. Wang, C., Deng, L., Hong, M., Akkaraju, G. R., Inoue, J., and Chen, Z. J. (2001) Nature 412, 346-351
15. Ciechanover, A. (1998) EMBO J. 17, 7151-7160
16. Ichijo, H., Nishida, E., Irie, K., ten Dijke, P., Saitoh, M., Moriguchi, T., Takagi, M., Matsumoto, K., Miyazono, K., and Gotoh, Y. (1997) Science 275, 90-94
17. Nishitoh, H., Saitoh, M., Mochida, Y., Takeda, K., Nakano, H., Rothe, M., Miyazono, K., and Ichijo, H. (1998) Mol. Cell 2, 389-395
18. Saitoh, M., Nishitoh, H., Fujii, M., Takeda, K., Tobiume, K., Sawada, Y., Kawabata, M., Miyazono, K., and Ichijo, H. (1998) EMBO J. 17, 2596-2606
19. Liu, H., Nishitoh, H., Ichijo, H., and Kyriakis, J. M. (2000) Mol. Cell. Biol. 20, 2198-2208
20. Li, X., Yang, Y., and Ashwell, J. D. (2002) Nature 416, 345-347
21. Brown, K. D., Hostager, B. S., and Bishop, G. A. (2002) J. Biol. Chem. 277, 19433-19438