-
1
-
-
76049118039
-
Age-standardized liver cancer incidence rates
-
American Cancer Society, Atlanta, Georgia
-
American Cancer Society. Age-standardized liver cancer incidence rates. Global Cancer Facts & Figures 2007 (2007), Atlanta, Georgia 18-23
-
(2007)
Global Cancer Facts & Figures 2007
, pp. 18-23
-
-
-
2
-
-
33748114343
-
The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
-
Perz J.F., Armstrong GL., Farrington L.A., Hutin Y.J., and Bell B.P. The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. J. Hepatol. 45 4 (2006) 529-538
-
(2006)
J. Hepatol.
, vol.45
, Issue.4
, pp. 529-538
-
-
Perz, J.F.1
Armstrong, GL.2
Farrington, L.A.3
Hutin, Y.J.4
Bell, B.P.5
-
3
-
-
67650874081
-
Cancer statistics 2009
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J., and Thun M.J. Cancer statistics 2009. CA Cancer J. Clin. 59 (2009) 225-249
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
4
-
-
63049133092
-
Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005
-
Altekruse S.F., McGlynn K.A., and Reichman M.E. Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005. J. Clin. Oncol. 27 (2009) 1485-1491
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 1485-1491
-
-
Altekruse, S.F.1
McGlynn, K.A.2
Reichman, M.E.3
-
5
-
-
47249128185
-
Trends in mortality from hepatocellular carcinoma in Europe, 1980-2004
-
Bosetti C., Levi F., Boffetta P., Lucchini F., Negri E., and La Vecchia C. Trends in mortality from hepatocellular carcinoma in Europe, 1980-2004. Hepatology 48 1 (2008) 137-145
-
(2008)
Hepatology
, vol.48
, Issue.1
, pp. 137-145
-
-
Bosetti, C.1
Levi, F.2
Boffetta, P.3
Lucchini, F.4
Negri, E.5
La Vecchia, C.6
-
6
-
-
41849092172
-
Epidemiology of viral hepatitis infections in an area of southern Italy with high incidence rates of liver cancer
-
Collaborating Study Group
-
Fusco M., Girardi E., Piselli P., Palombino R., Polesel J., Maione C., Scognamiglio P., Pisanti F.A., Solmone M., Di Cicco P., Ippolito G., Franceschi S., Serraino D., and Collaborating Study Group. Epidemiology of viral hepatitis infections in an area of southern Italy with high incidence rates of liver cancer. Eur. J. Cancer 44 6 (2008) 847-853
-
(2008)
Eur. J. Cancer
, vol.44
, Issue.6
, pp. 847-853
-
-
Fusco, M.1
Girardi, E.2
Piselli, P.3
Palombino, R.4
Polesel, J.5
Maione, C.6
Scognamiglio, P.7
Pisanti, F.A.8
Solmone, M.9
Di Cicco, P.10
Ippolito, G.11
Franceschi, S.12
Serraino, D.13
-
7
-
-
76049122940
-
Naples cancer registry
-
Zanetti R., et al. (Ed), Il Pensiero Scientifico Editore, Roma
-
Fusco M., Palombino R., and Montella M. Naples cancer registry. In: Zanetti R., et al. (Ed). (e mortality mortality ds): Cancer in Italy: incidence data from Cancer Registries, Third Volume: 1993-1998 (2002), Il Pensiero Scientifico Editore, Roma
-
(2002)
(e mortality mortality ds): Cancer in Italy: incidence data from Cancer Registries, Third Volume: 1993-1998
-
-
Fusco, M.1
Palombino, R.2
Montella, M.3
-
8
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: from genes to environment
-
Farazi P.A., and DePinho R.A. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat. Rev. Cancer 6 9 (2006) 674-687
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.9
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
9
-
-
56749107194
-
The tumor microenvironment and its contribution to tumor evolution toward metastasis
-
Lorusso G., and Riegg C. The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem. Cell Biol. 130 (2008) 1091-1103
-
(2008)
Histochem. Cell Biol.
, vol.130
, pp. 1091-1103
-
-
Lorusso, G.1
Riegg, C.2
-
10
-
-
53549102755
-
The tumor microenvironment and its role in promoting tumor growth
-
Whiteside T.L. The tumor microenvironment and its role in promoting tumor growth. Oncogene 27 (2008) 5904-5912
-
(2008)
Oncogene
, vol.27
, pp. 5904-5912
-
-
Whiteside, T.L.1
-
11
-
-
0033932001
-
Recovery, persistence, and sequelae in hepatitis C virus infection: a perspective on long-term outcome
-
Alter H.J., and Seeff L.B. Recovery, persistence, and sequelae in hepatitis C virus infection: a perspective on long-term outcome. Semin. Liver Dis. 20 (2000) 17-35
-
(2000)
Semin. Liver Dis.
, vol.20
, pp. 17-35
-
-
Alter, H.J.1
Seeff, L.B.2
-
12
-
-
0028158455
-
Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children
-
Lai M.E., Mazzoleni A.P., and Argiolu F. Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children. Lancet 343 (1994) 388-390
-
(1994)
Lancet
, vol.343
, pp. 388-390
-
-
Lai, M.E.1
Mazzoleni, A.P.2
Argiolu, F.3
-
13
-
-
7444256169
-
Genetic diversity and evolution of hepatitis C virus-15 years on
-
Simmonds P. Genetic diversity and evolution of hepatitis C virus-15 years on. J. Gen. Virol. 85 (2004) 3173-3188
-
(2004)
J. Gen. Virol.
, vol.85
, pp. 3173-3188
-
-
Simmonds, P.1
-
14
-
-
58649107348
-
Microenvironment changes (in pH) affect VEGF alternative splicing
-
Elias A.P., and Dias S. Microenvironment changes (in pH) affect VEGF alternative splicing. Cancer Microenviron. 1 (2008) 131-139
-
(2008)
Cancer Microenviron.
, vol.1
, pp. 131-139
-
-
Elias, A.P.1
Dias, S.2
-
15
-
-
58649083678
-
The prometastatic microenvironment of the liver
-
Vidal-Vanaclocha F. The prometastatic microenvironment of the liver. Cancer Microenviron. 1 (2008) 113-129
-
(2008)
Cancer Microenviron.
, vol.1
, pp. 113-129
-
-
Vidal-Vanaclocha, F.1
-
16
-
-
0036289148
-
Detection of neutralizing antibodies to hepatitis C virus using a biliary cell infection model
-
Bichr S., Rende-Fournier R., Vona G., Yamamoto A.M., Depla E., Geert Maertens G., and Christian Bréchot C. Detection of neutralizing antibodies to hepatitis C virus using a biliary cell infection model. J. Gen. Virol. 83 (2002) 1673-1678
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 1673-1678
-
-
Bichr, S.1
Rende-Fournier, R.2
Vona, G.3
Yamamoto, A.M.4
Depla, E.5
Geert Maertens, G.6
Christian Bréchot, C.7
-
17
-
-
33745527481
-
Viral hepatitis and liver cancer: the case of hepatitis C
-
Levrero M. Viral hepatitis and liver cancer: the case of hepatitis C. Oncogene 25 27 (2006) 3834-3847
-
(2006)
Oncogene
, vol.25
, Issue.27
, pp. 3834-3847
-
-
Levrero, M.1
-
18
-
-
33645297935
-
Natural killer cells: primary target for hepatitis C virus immune evasion strategies?
-
Golden-Mason L., and Rosen H.R. Natural killer cells: primary target for hepatitis C virus immune evasion strategies?. Liver Transplant. 12 3 (2006) 363-372
-
(2006)
Liver Transplant.
, vol.12
, Issue.3
, pp. 363-372
-
-
Golden-Mason, L.1
Rosen, H.R.2
-
19
-
-
23944467250
-
Adaptive immune responses in acute and chronic hepatitis C virus infection
-
Bowen D.G., and Walker C.M. Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature 436 7053 (2005) 946-952
-
(2005)
Nature
, vol.436
, Issue.7053
, pp. 946-952
-
-
Bowen, D.G.1
Walker, C.M.2
-
20
-
-
0035914925
-
Determinants of viral clearance and persistence during acute hepatitis C virus infection
-
Thimme R., Oldach D., Chang K.M., Steiger C., Ray S.C., and Chisari F.V. Determinants of viral clearance and persistence during acute hepatitis C virus infection. J. Exp. Med. 194 10 (2001) 1395-1406
-
(2001)
J. Exp. Med.
, vol.194
, Issue.10
, pp. 1395-1406
-
-
Thimme, R.1
Oldach, D.2
Chang, K.M.3
Steiger, C.4
Ray, S.C.5
Chisari, F.V.6
-
21
-
-
0037180506
-
Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease
-
Thimme R., Bukh J., Spangenberg H.C., Wieland S., Pemberton J., Steiger C., Govindarajan S., Purcell R.H., and Chisari F.V. Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease. Proc. Natl. Acad. Sci. U. S. A 26 99(24) (2002) 15661-15668
-
(2002)
Proc. Natl. Acad. Sci. U. S. A
, vol.26
, Issue.99 24
, pp. 15661-15668
-
-
Thimme, R.1
Bukh, J.2
Spangenberg, H.C.3
Wieland, S.4
Pemberton, J.5
Steiger, C.6
Govindarajan, S.7
Purcell, R.H.8
Chisari, F.V.9
-
22
-
-
33846085749
-
Immunopathogenesis of hepatitis B virus infection
-
Chang J.J., and Lewin S.R. Immunopathogenesis of hepatitis B virus infection. Immunol. Cell Biol. 85 1 (2007) 16-23
-
(2007)
Immunol. Cell Biol.
, vol.85
, Issue.1
, pp. 16-23
-
-
Chang, J.J.1
Lewin, S.R.2
-
23
-
-
17844403232
-
Hepatitis Interventional Therapy Group. A randomized, double-blind trial comparing pegylated interferon alfa-2b to interferon alfa-2b as initial treatment for chronic hepatitis C
-
Lindsay K.L., Trepo C., Heintges T., Shiffman M.L., Gordon S.C., Hoefs J.C., Schiff E.R., Goodman Z.D., Laughlin M., Yao R., and Albrecht J.K. Hepatitis Interventional Therapy Group. A randomized, double-blind trial comparing pegylated interferon alfa-2b to interferon alfa-2b as initial treatment for chronic hepatitis C. Hepatology 34 (2001) 395-403
-
(2001)
Hepatology
, vol.34
, pp. 395-403
-
-
Lindsay, K.L.1
Trepo, C.2
Heintges, T.3
Shiffman, M.L.4
Gordon, S.C.5
Hoefs, J.C.6
Schiff, E.R.7
Goodman, Z.D.8
Laughlin, M.9
Yao, R.10
Albrecht, J.K.11
-
24
-
-
0035934568
-
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial
-
Manns M.P., McHutchison J.G., Gordon S.C., et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 358 (2001) 958-965
-
(2001)
Lancet
, vol.358
, pp. 958-965
-
-
Manns, M.P.1
McHutchison, J.G.2
Gordon, S.C.3
-
25
-
-
68549136610
-
The pattern of pegylated interferon-alpha2b and ribavirin treatment failure in cirrhotic patients depends on hepatitis C virus genotype
-
Aghemo A., Rumi M.G., Monico S., Prati G.M., D'Ambrosio R., Donato M.F., and Colombo M. The pattern of pegylated interferon-alpha2b and ribavirin treatment failure in cirrhotic patients depends on hepatitis C virus genotype. Antivir. Ther. 14 4 (2009) 577-584
-
(2009)
Antivir. Ther.
, vol.14
, Issue.4
, pp. 577-584
-
-
Aghemo, A.1
Rumi, M.G.2
Monico, S.3
Prati, G.M.4
D'Ambrosio, R.5
Donato, M.F.6
Colombo, M.7
-
26
-
-
70349554670
-
Efficacy of chronic hepatitis C therapy in community-based trials
-
Marotta P., Hueppe D., Zehnter E., Kwo P., and Jacobson I. Efficacy of chronic hepatitis C therapy in community-based trials. Clin. Gastroenterol. Hepatol. 7 10 (2009) 1028-1036
-
(2009)
Clin. Gastroenterol. Hepatol.
, vol.7
, Issue.10
, pp. 1028-1036
-
-
Marotta, P.1
Hueppe, D.2
Zehnter, E.3
Kwo, P.4
Jacobson, I.5
-
27
-
-
0032475822
-
Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy
-
Neumann A.U., Lam N.P., Dahari H., Gretch D.R., Wiley T.E., Layden T.J., and Perelson A.S. Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy. Science 282 5386 (1998) 103-107
-
(1998)
Science
, vol.282
, Issue.5386
, pp. 103-107
-
-
Neumann, A.U.1
Lam, N.P.2
Dahari, H.3
Gretch, D.R.4
Wiley, T.E.5
Layden, T.J.6
Perelson, A.S.7
-
28
-
-
54449083925
-
Molecular targeted therapies in hepatocellular carcinoma
-
Llovet J.M., and Bruix J. Molecular targeted therapies in hepatocellular carcinoma. Hepatology 48 4 (2008) 1312-1327
-
(2008)
Hepatology
, vol.48
, Issue.4
, pp. 1312-1327
-
-
Llovet, J.M.1
Bruix, J.2
-
29
-
-
0031807538
-
Expression of vascular endothelial growth factor in human hepatocellular carcinoma
-
Yamaguchi R., Yano H., Iemura A., Ogasawara S., Haramaki M., and Kojiro M. Expression of vascular endothelial growth factor in human hepatocellular carcinoma. Hepatology 28 1 (1998) 68-77
-
(1998)
Hepatology
, vol.28
, Issue.1
, pp. 68-77
-
-
Yamaguchi, R.1
Yano, H.2
Iemura, A.3
Ogasawara, S.4
Haramaki, M.5
Kojiro, M.6
-
30
-
-
0032939205
-
Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma
-
Tanaka S., Mori M., Sakamoto Y., Makuuchi M., Sugimachi K., and Wands J.R. Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma. J. Clin. Invest. 103 3 (1999) 341-345
-
(1999)
J. Clin. Invest.
, vol.103
, Issue.3
, pp. 341-345
-
-
Tanaka, S.1
Mori, M.2
Sakamoto, Y.3
Makuuchi, M.4
Sugimachi, K.5
Wands, J.R.6
-
31
-
-
0038374813
-
Angiopoietins and Tie-2 expression in angiogenesis and proliferation of human hepatocellular carcinoma
-
Mitsuhashi N., Shimizu H., Ohtsuka M., Wakabayashi Y., Ito H., Kimura F., Yoshidome H., Kato A., Nukui Y., and Miyazaki M. Angiopoietins and Tie-2 expression in angiogenesis and proliferation of human hepatocellular carcinoma. Hepatology 37 5 (2003) 1105-1113
-
(2003)
Hepatology
, vol.37
, Issue.5
, pp. 1105-1113
-
-
Mitsuhashi, N.1
Shimizu, H.2
Ohtsuka, M.3
Wakabayashi, Y.4
Ito, H.5
Kimura, F.6
Yoshidome, H.7
Kato, A.8
Nukui, Y.9
Miyazaki, M.10
-
32
-
-
0036699940
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Thorgeirsson S.S., and Grisham J.W. Molecular pathogenesis of human hepatocellular carcinoma. Nat. Genet. 31 4 (2002) 339-346
-
(2002)
Nat. Genet.
, vol.31
, Issue.4
, pp. 339-346
-
-
Thorgeirsson, S.S.1
Grisham, J.W.2
-
33
-
-
33144465731
-
Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells
-
Ozturk N., Erdal E., Mumcuoglu M., Akcali K.C., Yalcin O., Senturk S., Arslan-Ergul A., Gur B., Yulug I., Cetin-Atalay R., Yakicier C., Yagci T., Tez M., and Ozturk M. Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells. Proc. Natl. Acad. Sci. U. S. A. 103 7 (2006) 2178-2183
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, Issue.7
, pp. 2178-2183
-
-
Ozturk, N.1
Erdal, E.2
Mumcuoglu, M.3
Akcali, K.C.4
Yalcin, O.5
Senturk, S.6
Arslan-Ergul, A.7
Gur, B.8
Yulug, I.9
Cetin-Atalay, R.10
Yakicier, C.11
Yagci, T.12
Tez, M.13
Ozturk, M.14
-
34
-
-
0028052302
-
The molecular pathogenesis of hepatocellular carcinoma
-
Moradpour D., and Wands J.R. The molecular pathogenesis of hepatocellular carcinoma. J. Viral Hepatitis 1 1 (1994) 17-31
-
(1994)
J. Viral Hepatitis
, vol.1
, Issue.1
, pp. 17-31
-
-
Moradpour, D.1
Wands, J.R.2
-
36
-
-
33745532794
-
Genetics of hepatocellular tumours
-
Laurent-Puig P., and Zucman-Rossi J. Genetics of hepatocellular tumours. Oncogene 25 27 (2006) 3778-3786
-
(2006)
Oncogene
, vol.25
, Issue.27
, pp. 3778-3786
-
-
Laurent-Puig, P.1
Zucman-Rossi, J.2
-
37
-
-
41849142290
-
Molecular mechanism underlying the functional loss of cyclin dependent kinase inhibitors p16 and p27 in hepatocellular carcinoma
-
Matsuda Y. Molecular mechanism underlying the functional loss of cyclin dependent kinase inhibitors p16 and p27 in hepatocellular carcinoma. World J. Gastroenterol. 14 11 (2008) 1734-1740
-
(2008)
World J. Gastroenterol.
, vol.14
, Issue.11
, pp. 1734-1740
-
-
Matsuda, Y.1
-
38
-
-
0032549704
-
The Ink4a tumour suppressor gene product, 19Arf, interacts with MDM2 and neutralizes DM2's inhibition of p53
-
Pomerantz J., Schreiber-Agus N., Liégeois N.J., Silverman A., Alland L., Chin L., Potes J., Chen K., Orlow I., Lee H.W., Cordon-Cardo C., and DePinho R.A. The Ink4a tumour suppressor gene product, 19Arf, interacts with MDM2 and neutralizes DM2's inhibition of p53. Cell 92 6 (1998) 713-723
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liégeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
39
-
-
35748972055
-
Issues affecting molecular staging in the management of patients with melanoma
-
Palmieri G., Casula M., Sini M.C., Ascierto P.A., and Cossu A. Issues affecting molecular staging in the management of patients with melanoma. J. Cell. Mol. Med. 11 5 (2007) 1052-1068
-
(2007)
J. Cell. Mol. Med.
, vol.11
, Issue.5
, pp. 1052-1068
-
-
Palmieri, G.1
Casula, M.2
Sini, M.C.3
Ascierto, P.A.4
Cossu, A.5
-
40
-
-
34547593907
-
Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: factors contributing to hepatocarcinogenesis
-
Chin R., Earnest-Silveira L., Koeberlein B., Franz S., Zentgraf H., Dong X., Gowans E., Bock C.T., and Torresi J. Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: factors contributing to hepatocarcinogenesis. J. J. Hepatol. 47 3 (2007) 325-337
-
(2007)
J. J. Hepatol.
, vol.47
, Issue.3
, pp. 325-337
-
-
Chin, R.1
Earnest-Silveira, L.2
Koeberlein, B.3
Franz, S.4
Zentgraf, H.5
Dong, X.6
Gowans, E.7
Bock, C.T.8
Torresi, J.9
-
41
-
-
33645976174
-
Ubiquitous activation of Ras and Jak/Stat pathways in human HCC
-
Calvisi D.F., Ladu S., Gorden A., Farina M., Conner E.A., Lee J.S., Factor V.M., and Thorgeirsson S.S. Ubiquitous activation of Ras and Jak/Stat pathways in human HCC. Gastroenterology 130 4 (2006) 1117-1128
-
(2006)
Gastroenterology
, vol.130
, Issue.4
, pp. 1117-1128
-
-
Calvisi, D.F.1
Ladu, S.2
Gorden, A.3
Farina, M.4
Conner, E.A.5
Lee, J.S.6
Factor, V.M.7
Thorgeirsson, S.S.8
-
42
-
-
36549013178
-
Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection
-
Schmitz K.J., Wohlschlaeger J., Lang H., Sotiropoulos G.C., Malago M., Steveling K., Reis H., Cicinnati V.R., Schmid K.W., and Baba H.A. Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection. J. Hepatol. 48 1 (2008) 83-90
-
(2008)
J. Hepatol.
, vol.48
, Issue.1
, pp. 83-90
-
-
Schmitz, K.J.1
Wohlschlaeger, J.2
Lang, H.3
Sotiropoulos, G.C.4
Malago, M.5
Steveling, K.6
Reis, H.7
Cicinnati, V.R.8
Schmid, K.W.9
Baba, H.A.10
-
43
-
-
2542473135
-
Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: its role in tumour progression and apoptosis
-
Huynh H., Nguyen T.T., Chow K.H., Tan P.H., Soo K.C., and Tran E. Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: its role in tumour progression and apoptosis. BMC Gastroenterol. 3 (2003) 19
-
(2003)
BMC Gastroenterol.
, vol.3
, pp. 19
-
-
Huynh, H.1
Nguyen, T.T.2
Chow, K.H.3
Tan, P.H.4
Soo, K.C.5
Tran, E.6
-
44
-
-
0035908493
-
Blocking oncogenic Ras signaling for cancer therapy
-
Adjei A.A. Blocking oncogenic Ras signaling for cancer therapy. J. Natl. Cancer Inst. 93 (2001) 1062-1074
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 1062-1074
-
-
Adjei, A.A.1
-
45
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H., Bignell G.R., Cox C., Stephens P., Edkins S., Clegg S., Teague J., Woffendin H., Garnett M.J., Bottomley W., Davis N., Dicks E., Ewing R., Floyd Y., Gray K., Hall S., Hawes R., Hughes J., Kosmidou V., Menzies A., Mould C., Parker A., Stevens C., Watt S., Hooper S., Wilson R., Jayatilake H., Gusterson B.A., Cooper C., Shipley J., Hargrave D., Pritchard-Jones K., Maitland N., Chenevix-Trench G., Riggins G.J., Bigner D.D., Palmieri G., Cossu A., Flanagan A., Nicholson A., Ho J.W., Leung S.Y., Yuen S.T., Weber B.L., Seigler H.F., Darrow T.L., Paterson H., Marais R., Marshall C.J., Wooster R., Stratton M.R., and Futreal P.A. Mutations of the BRAF gene in human cancer. Nature 417 6892 (2002) 949-954
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmieri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
46
-
-
0037624602
-
Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma
-
Tannapfel A., Sommerer F., Benicke M., Katalinic A., Uhlmann D., Witzigmann H., Hauss J., and Wittekind C. Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma. Gut 52 5 (2003) 706-712
-
(2003)
Gut
, vol.52
, Issue.5
, pp. 706-712
-
-
Tannapfel, A.1
Sommerer, F.2
Benicke, M.3
Katalinic, A.4
Uhlmann, D.5
Witzigmann, H.6
Hauss, J.7
Wittekind, C.8
-
47
-
-
33749319933
-
Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells
-
Lee H.C., Tian B., Sedivy J.M., Wands J.R., and Kim M. Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells. Gastroenterology 131 4 (2006) 1208-1217
-
(2006)
Gastroenterology
, vol.131
, Issue.4
, pp. 1208-1217
-
-
Lee, H.C.1
Tian, B.2
Sedivy, J.M.3
Wands, J.R.4
Kim, M.5
-
48
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer C., Kinzier K.W., and Volgestein B. Genetic instabilities in human cancers. Nature 396 6712 (1998) 643-649
-
(1998)
Nature
, vol.396
, Issue.6712
, pp. 643-649
-
-
Lengauer, C.1
Kinzier, K.W.2
Volgestein, B.3
-
49
-
-
0038505659
-
Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis
-
Edamoto Y., Hara A., Biernat W., Terracciano L., Cathomas G., Riehle H.M., Matsuda M., Fujii H., Scoazec J.Y., and Ohgaki H. Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis. Int. J. Cancer 106 3 (2003) 334-341
-
(2003)
Int. J. Cancer
, vol.106
, Issue.3
, pp. 334-341
-
-
Edamoto, Y.1
Hara, A.2
Biernat, W.3
Terracciano, L.4
Cathomas, G.5
Riehle, H.M.6
Matsuda, M.7
Fujii, H.8
Scoazec, J.Y.9
Ohgaki, H.10
-
50
-
-
57349182990
-
Pathogenesis of HCV-associated HCC: dual-pass carcinogenesis through activation of oxidative stress and intracellular signaling
-
Koike K. Pathogenesis of HCV-associated HCC: dual-pass carcinogenesis through activation of oxidative stress and intracellular signaling. Hepatol. Res. 37 Suppl. 2 (2007) S115-S120
-
(2007)
Hepatol. Res.
, vol.37
, Issue.SUPPL. 2
-
-
Koike, K.1
-
51
-
-
57349090407
-
Gene expression in fixed tissues and outcome in hepatocellular carcinoma
-
Hoshida Y., Villanueva A., Kobayashi M., Peix J., Chiang D.Y., Camargo A., Gupta S., Moore J., Wrobel M.J., Lerner J., Reich M., Chan J.A., Glickman J.N., Ikeda K., Hashimoto M., Watanabe G., Daidone M.G., Roayaie S., Schwartz M., Thung S., Salvesen H.B., Gabriel S., Mazzaferro V., Bruix J., Friedman S.L., Kumada H., Llovet J.M., and Golub T.R. Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N. Engl. J. Med. 359 19 (2008) 1995-2004
-
(2008)
N. Engl. J. Med.
, vol.359
, Issue.19
, pp. 1995-2004
-
-
Hoshida, Y.1
Villanueva, A.2
Kobayashi, M.3
Peix, J.4
Chiang, D.Y.5
Camargo, A.6
Gupta, S.7
Moore, J.8
Wrobel, M.J.9
Lerner, J.10
Reich, M.11
Chan, J.A.12
Glickman, J.N.13
Ikeda, K.14
Hashimoto, M.15
Watanabe, G.16
Daidone, M.G.17
Roayaie, S.18
Schwartz, M.19
Thung, S.20
Salvesen, H.B.21
Gabriel, S.22
Mazzaferro, V.23
Bruix, J.24
Friedman, S.L.25
Kumada, H.26
Llovet, J.M.27
Golub, T.R.28
more..
-
52
-
-
48949096061
-
Hepatic fibrogenesis in response to chronic liver injury: novel insights on the role of cell-to-cell interaction and transition
-
Svegliati-Baroni G., De Minicis S., and Marzioni M. Hepatic fibrogenesis in response to chronic liver injury: novel insights on the role of cell-to-cell interaction and transition. Liver Int. 28 8 (2008) 1052-1064
-
(2008)
Liver Int.
, vol.28
, Issue.8
, pp. 1052-1064
-
-
Svegliati-Baroni, G.1
De Minicis, S.2
Marzioni, M.3
-
53
-
-
0041402775
-
Shaping the immune response to parasites: role of dendritic cells
-
Sher A., Pearce E., and Kaye P. Shaping the immune response to parasites: role of dendritic cells. Curr. Opin. Immunol. 15 4 (2003) 421-429
-
(2003)
Curr. Opin. Immunol.
, vol.15
, Issue.4
, pp. 421-429
-
-
Sher, A.1
Pearce, E.2
Kaye, P.3
-
54
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau J., and Steinman R.M. Dendritic cells and the control of immunity. Nature 392 6673 (1998) 245-252
-
(1998)
Nature
, vol.392
, Issue.6673
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
55
-
-
33751180964
-
Liver immunity and tumour surveillance
-
Canning C., O ' Brien M., Hegarty J., and O ' Farrelly C. Liver immunity and tumour surveillance. Immunol. Lett. 107 2 (2006) 83-88
-
(2006)
Immunol. Lett.
, vol.107
, Issue.2
, pp. 83-88
-
-
Canning, C.1
O ' Brien, M.2
Hegarty, J.3
O ' Farrelly, C.4
-
56
-
-
23244437654
-
Innate immune responses to infection
-
quiz 250
-
Tosi M.F. Innate immune responses to infection. J. Allergy Clin. Immunol. 116 2 (2005) 241-249 quiz 250
-
(2005)
J. Allergy Clin. Immunol.
, vol.116
, Issue.2
, pp. 241-249
-
-
Tosi, M.F.1
-
57
-
-
41349104243
-
Toll-like receptors regulation of viral infection and disease
-
Thompson J.M., and Iwasaki A. Toll-like receptors regulation of viral infection and disease. Adv. Drug Deliv. Rev. 60 7 (2008) 786-794
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, Issue.7
, pp. 786-794
-
-
Thompson, J.M.1
Iwasaki, A.2
-
58
-
-
4344658402
-
Induction and regulation of IFNs during viral infections
-
Malmgaard L. Induction and regulation of IFNs during viral infections. J. Interferon. Cytokine Res. 24 8 (2004) 439-454
-
(2004)
J. Interferon. Cytokine Res.
, vol.24
, Issue.8
, pp. 439-454
-
-
Malmgaard, L.1
-
59
-
-
23944485662
-
Evasion of intracellular host defence by hepatitis C virus
-
Gale Jr. M., and Foy E.M. Evasion of intracellular host defence by hepatitis C virus. Nature 436 (2005) 939-945
-
(2005)
Nature
, vol.436
, pp. 939-945
-
-
Gale Jr., M.1
Foy, E.M.2
-
60
-
-
0034769960
-
Viruses and interferons
-
Sen G.C. Viruses and interferons. Annu. Rev. Microbiol. 55 (2001) 255-281
-
(2001)
Annu. Rev. Microbiol.
, vol.55
, pp. 255-281
-
-
Sen, G.C.1
-
61
-
-
0036717195
-
NF-kappaB, chemokine gene transcription and tumour growth
-
Richmond A. NF-kappaB, chemokine gene transcription and tumour growth. Nat. Rev. Immunol. 2 9 (2002) 664-674
-
(2002)
Nat. Rev. Immunol.
, vol.2
, Issue.9
, pp. 664-674
-
-
Richmond, A.1
-
62
-
-
17544383005
-
Activation of nuclear factor-κB in hepatitis C virus infection: implications for pathogenesis and hepatocarcinogenesis
-
Tai D.I., Tsai S.L., Chen Y.M., Chuang Y.L., Peng C.Y., Sheen I.S., Yeh C.T., Chang K.S., Huang S.N., Kuo G.C., and Liaw Y.F. Activation of nuclear factor-κB in hepatitis C virus infection: implications for pathogenesis and hepatocarcinogenesis. Hepatology 31 3 (2000) 656-664
-
(2000)
Hepatology
, vol.31
, Issue.3
, pp. 656-664
-
-
Tai, D.I.1
Tsai, S.L.2
Chen, Y.M.3
Chuang, Y.L.4
Peng, C.Y.5
Sheen, I.S.6
Yeh, C.T.7
Chang, K.S.8
Huang, S.N.9
Kuo, G.C.10
Liaw, Y.F.11
-
63
-
-
0031058823
-
New insights into the mechanisms of interferon α: an immunoregulatory and anti-inflammatory cytokine
-
Tilg H. New insights into the mechanisms of interferon α: an immunoregulatory and anti-inflammatory cytokine. Gastroenterology 112 3 (1997) 1017-1021
-
(1997)
Gastroenterology
, vol.112
, Issue.3
, pp. 1017-1021
-
-
Tilg, H.1
-
64
-
-
14644415511
-
Pathogen-induced private conversations between natural killer and dendritic cells
-
Chiesa M.D., Sivori S., Castriconi R., et al. Pathogen-induced private conversations between natural killer and dendritic cells. Trends Microbiol. 13 (2005) 128-136
-
(2005)
Trends Microbiol.
, vol.13
, pp. 128-136
-
-
Chiesa, M.D.1
Sivori, S.2
Castriconi, R.3
-
65
-
-
0034041033
-
Immunobiology of dendritic cells
-
Banchereau J., Briere F., Caux C., Davoust J., Lebecque S., Liu Y.J., Pulendran B., and Palucka K. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18 (2000) 767-811
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 767-811
-
-
Banchereau, J.1
Briere, F.2
Caux, C.3
Davoust, J.4
Lebecque, S.5
Liu, Y.J.6
Pulendran, B.7
Palucka, K.8
-
66
-
-
0035903288
-
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
-
Kadowaki N., Ho S., Antonenko S., Malefyt R.W., Kastelein R.A., Bazan F., and Liu Y.J. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194 6 (2001) 863-869
-
(2001)
J. Exp. Med.
, vol.194
, Issue.6
, pp. 863-869
-
-
Kadowaki, N.1
Ho, S.2
Antonenko, S.3
Malefyt, R.W.4
Kastelein, R.A.5
Bazan, F.6
Liu, Y.J.7
-
67
-
-
0037310821
-
Critical role of MHC class I-related chain A and B expression on IFN-alpha-stimulated dendritic cells in NK cell activation: impairment in chronic hepatitis C virus infection
-
Jinushi M., Takehara T., Kanto T., Tatsumi T., Groh V., Spies T., Miyagi T., Suzuki T., Sasaki Y., and Hayashi N. Critical role of MHC class I-related chain A and B expression on IFN-alpha-stimulated dendritic cells in NK cell activation: impairment in chronic hepatitis C virus infection. J. J. Immunol. 170 3 (2003) 1249-1256
-
(2003)
J. J. Immunol.
, vol.170
, Issue.3
, pp. 1249-1256
-
-
Jinushi, M.1
Takehara, T.2
Kanto, T.3
Tatsumi, T.4
Groh, V.5
Spies, T.6
Miyagi, T.7
Suzuki, T.8
Sasaki, Y.9
Hayashi, N.10
-
68
-
-
33645038201
-
Immunopathogenesis of hepatitis C virus infection: multifaceted strategies subverting innate and adaptive immunity
-
Kanto T., and Hayashi N. Immunopathogenesis of hepatitis C virus infection: multifaceted strategies subverting innate and adaptive immunity. Intern. Med. 45 4 (2006) 183-191
-
(2006)
Intern. Med.
, vol.45
, Issue.4
, pp. 183-191
-
-
Kanto, T.1
Hayashi, N.2
-
69
-
-
0034691609
-
Hepatitis C virus glycoprotein E2 binding to CD81: the role of E1E2 cleavage and protein glycosylation in bioactivity
-
Chan-Fook C., Jiang W.R., Clarke B.E., Zitzmann N., Maidens C., McKeating J.A., and Jones I.M. Hepatitis C virus glycoprotein E2 binding to CD81: the role of E1E2 cleavage and protein glycosylation in bioactivity. Virology 273 (2000) 60-66
-
(2000)
Virology
, vol.273
, pp. 60-66
-
-
Chan-Fook, C.1
Jiang, W.R.2
Clarke, B.E.3
Zitzmann, N.4
Maidens, C.5
McKeating, J.A.6
Jones, I.M.7
-
70
-
-
0037033363
-
Binding of the hepatitis C virus envelope protein E2 to CD81 inhibits natural killer cell functions
-
Tseng C.T., and Klimpel G.R. Binding of the hepatitis C virus envelope protein E2 to CD81 inhibits natural killer cell functions. J. Exp. Med. 195 1 (2002) 43-49
-
(2002)
J. Exp. Med.
, vol.195
, Issue.1
, pp. 43-49
-
-
Tseng, C.T.1
Klimpel, G.R.2
-
71
-
-
45749125674
-
Relationship of peripheral blood CD4-positive T cells to carcinogenesis in patients with HCV-related chronic hepatitis and liver cirrhosis
-
Matsui T., Nagai H., Sumino Y., and Miki K. Relationship of peripheral blood CD4-positive T cells to carcinogenesis in patients with HCV-related chronic hepatitis and liver cirrhosis. Cancer Chemother. Pharmacol. 62 3 (2008) 401-406
-
(2008)
Cancer Chemother. Pharmacol.
, vol.62
, Issue.3
, pp. 401-406
-
-
Matsui, T.1
Nagai, H.2
Sumino, Y.3
Miki, K.4
-
72
-
-
0035062597
-
Noncytolytic control of viral infections by the innate and adaptive immune response
-
Guidotti L.G., and Chisari F.V. Noncytolytic control of viral infections by the innate and adaptive immune response. Annu. Rev. Immunol. 19 (2001) 65-91
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 65-91
-
-
Guidotti, L.G.1
Chisari, F.V.2
-
73
-
-
0036191172
-
Interferon-gamma inhibits replication of subgenomic and genomic hepatitis C virus RNAs
-
Frese M., Schwärzle V., Barth K., Krieger N., Lohmann V., Mihm S., Haller O., and Bartenschlager R. Interferon-gamma inhibits replication of subgenomic and genomic hepatitis C virus RNAs. Hepatology 35 3 (2002) 694-703
-
(2002)
Hepatology
, vol.35
, Issue.3
, pp. 694-703
-
-
Frese, M.1
Schwärzle, V.2
Barth, K.3
Krieger, N.4
Lohmann, V.5
Mihm, S.6
Haller, O.7
Bartenschlager, R.8
-
74
-
-
0041735102
-
Regulatory T cells control the development of allergic disease and asthma
-
quiz 488
-
Umetsu D.T., Akbari O., and Dekruyff R.H. Regulatory T cells control the development of allergic disease and asthma. J. Allergy Clin. Immunol. 112(3) (2003) 480-487 quiz 488
-
(2003)
J. Allergy Clin. Immunol.
, vol.112 3
, pp. 480-487
-
-
Umetsu, D.T.1
Akbari, O.2
Dekruyff, R.H.3
-
75
-
-
33845420396
-
The role of cytokines in hepatocellular carcinoma
-
Budhu A., and Wang X.W. The role of cytokines in hepatocellular carcinoma. J. Leukoc. Biol. 80 6 (2006) 1197-1213
-
(2006)
J. Leukoc. Biol.
, vol.80
, Issue.6
, pp. 1197-1213
-
-
Budhu, A.1
Wang, X.W.2
-
76
-
-
10244225383
-
Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response
-
Missale G., Bertoni R., Lamonaca V., Valli A., Massari M., Mori C., Rumi M.G., Houghton M., Fiaccadori F., and Ferrari C. Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response. J. Clin. Invest. 98 3 (1996) 706-714
-
(1996)
J. Clin. Invest.
, vol.98
, Issue.3
, pp. 706-714
-
-
Missale, G.1
Bertoni, R.2
Lamonaca, V.3
Valli, A.4
Massari, M.5
Mori, C.6
Rumi, M.G.7
Houghton, M.8
Fiaccadori, F.9
Ferrari, C.10
-
77
-
-
0032841846
-
Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence
-
Cerny A., and Chisari F.V. Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence. Hepatology 30 3 (1999) 595-601
-
(1999)
Hepatology
, vol.30
, Issue.3
, pp. 595-601
-
-
Cerny, A.1
Chisari, F.V.2
-
78
-
-
0032832514
-
Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T cell response in acute hepatitis C
-
Gerlach J.T., Diepolder H.M., Jung M.C., Gruener N.H., Schraut W.W., Zachoval R., Hoffmann R., Schirren C.A., Santantonio T., and Pape G.R. Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T cell response in acute hepatitis C. Gastroenterology 117 4 (1999) 933-941
-
(1999)
Gastroenterology
, vol.117
, Issue.4
, pp. 933-941
-
-
Gerlach, J.T.1
Diepolder, H.M.2
Jung, M.C.3
Gruener, N.H.4
Schraut, W.W.5
Zachoval, R.6
Hoffmann, R.7
Schirren, C.A.8
Santantonio, T.9
Pape, G.R.10
-
79
-
-
0036891826
-
Broad specificity of virus-specific CD4+ T-helper-cell responses in resolved hepatitis C virus infection
-
Day C.L., Lauer G.M., Robbins G.K., McGovern B., Wurcel A.G., Gandhi R.T., Chung R.T., and Walker B.D. Broad specificity of virus-specific CD4+ T-helper-cell responses in resolved hepatitis C virus infection. J. Virol. 76 24 (2002) 12584-12595
-
(2002)
J. Virol.
, vol.76
, Issue.24
, pp. 12584-12595
-
-
Day, C.L.1
Lauer, G.M.2
Robbins, G.K.3
McGovern, B.4
Wurcel, A.G.5
Gandhi, R.T.6
Chung, R.T.7
Walker, B.D.8
-
80
-
-
0033119925
-
Analysis of a successful immune response against hepatitis C virus
-
Cooper S., Erickson A.L., Adams E.J., Kansopon J., Weiner A.J., Chien D.Y., Houghton M., Parham P., and Walker C.M. Analysis of a successful immune response against hepatitis C virus. Immunity 10 4 (1999) 439-449
-
(1999)
Immunity
, vol.10
, Issue.4
, pp. 439-449
-
-
Cooper, S.1
Erickson, A.L.2
Adams, E.J.3
Kansopon, J.4
Weiner, A.J.5
Chien, D.Y.6
Houghton, M.7
Parham, P.8
Walker, C.M.9
-
81
-
-
0038543543
-
Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection
-
Shoukry N.H., Grakoui A., Houghton M., Chien D.Y., Ghrayeb J., Reimann K.A., and Walker C.M. Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection. J. Exp. Med. 197 12 (2003) 1645-1655
-
(2003)
J. Exp. Med.
, vol.197
, Issue.12
, pp. 1645-1655
-
-
Shoukry, N.H.1
Grakoui, A.2
Houghton, M.3
Chien, D.Y.4
Ghrayeb, J.5
Reimann, K.A.6
Walker, C.M.7
-
82
-
-
0033829854
-
CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained
-
Lechner F., Gruener N.H., Urbani S., Uggeri J., Santantonio T., Kammer A.R., Cerny A., Phillips R., Ferrari C., Pape G.R., and Klenerman P. CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained. Eur. J. Immunol. 30 9 (2000) 2479-2487
-
(2000)
Eur. J. Immunol.
, vol.30
, Issue.9
, pp. 2479-2487
-
-
Lechner, F.1
Gruener, N.H.2
Urbani, S.3
Uggeri, J.4
Santantonio, T.5
Kammer, A.R.6
Cerny, A.7
Phillips, R.8
Ferrari, C.9
Pape, G.R.10
Klenerman, P.11
-
83
-
-
13044313467
-
Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers
-
He X.S., Rehermann B., López-Labrador F.X., Boisvert J., Cheung R., Mumm J., Wedemeyer H., Berenguer M., Wright T.L., Davis M.M., and Greenberg H.B. Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers. Proc. Natl. Acad. Sci. U. S. A. 96 10 (1999) 5692-5697
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, Issue.10
, pp. 5692-5697
-
-
He, X.S.1
Rehermann, B.2
López-Labrador, F.X.3
Boisvert, J.4
Cheung, R.5
Mumm, J.6
Wedemeyer, H.7
Berenguer, M.8
Wright, T.L.9
Davis, M.M.10
Greenberg, H.B.11
-
84
-
-
17644444485
-
Analysis of successful immune responses in persons infected with hepatitis C virus
-
Lechner F., Wong D.K., Dunbar P.R., Chapman R., Chung R.T., Dohrenwend P., Robbins G., Phillips R., Klenerman P., and Walker B.D. Analysis of successful immune responses in persons infected with hepatitis C virus. J. Exp. Med. 191 9 (2000) 1499-1512
-
(2000)
J. Exp. Med.
, vol.191
, Issue.9
, pp. 1499-1512
-
-
Lechner, F.1
Wong, D.K.2
Dunbar, P.R.3
Chapman, R.4
Chung, R.T.5
Dohrenwend, P.6
Robbins, G.7
Phillips, R.8
Klenerman, P.9
Walker, B.D.10
-
85
-
-
0142178211
-
HCV persistence and immune evasion in the absence of memory T cell help
-
Grakoui A., Shoukry N.H., Woollard D.J., Han J.H., Hanson H.L., Ghrayeb J., Murthy K.K., Rice C.M., and Walker C.M. HCV persistence and immune evasion in the absence of memory T cell help. Science 302 5645 (2003) 659-662
-
(2003)
Science
, vol.302
, Issue.5645
, pp. 659-662
-
-
Grakoui, A.1
Shoukry, N.H.2
Woollard, D.J.3
Han, J.H.4
Hanson, H.L.5
Ghrayeb, J.6
Murthy, K.K.7
Rice, C.M.8
Walker, C.M.9
-
86
-
-
0034121558
-
Increases in intrahepatic CD68 positive cells, MAC387 positive cells, and proinflammatory cytokines (particularly interleukin 18) in chronic hepatitis C infection
-
McGuinness P.H., Painter D., Davies S., and McCaughan G.W. Increases in intrahepatic CD68 positive cells, MAC387 positive cells, and proinflammatory cytokines (particularly interleukin 18) in chronic hepatitis C infection. Gut 46 2 (2000) 260-269
-
(2000)
Gut
, vol.46
, Issue.2
, pp. 260-269
-
-
McGuinness, P.H.1
Painter, D.2
Davies, S.3
McCaughan, G.W.4
-
87
-
-
0037086525
-
CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons
-
MacDonald A.J., Duffy M., Brady M.T., McKiernan S., Hall W., Hegarty J., Curry M., and Mills K.H. CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons. J. Infect. Dis. 185 6 (2002) 720-727
-
(2002)
J. Infect. Dis.
, vol.185
, Issue.6
, pp. 720-727
-
-
MacDonald, A.J.1
Duffy, M.2
Brady, M.T.3
McKiernan, S.4
Hall, W.5
Hegarty, J.6
Curry, M.7
Mills, K.H.8
-
88
-
-
17844371667
-
Preferential loss of IL-2-secreting CD4+ T helper cells in chronic HCV infection
-
Semmo N., Day C.L., Ward S.M., Lucas M., Harcourt G., Loughry A., and Klenerman P. Preferential loss of IL-2-secreting CD4+ T helper cells in chronic HCV infection. Hepatology 41 5 (2005) 1019-1028
-
(2005)
Hepatology
, vol.41
, Issue.5
, pp. 1019-1028
-
-
Semmo, N.1
Day, C.L.2
Ward, S.M.3
Lucas, M.4
Harcourt, G.5
Loughry, A.6
Klenerman, P.7
-
89
-
-
0345017746
-
Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection
-
Sugimoto K., Ikeda F., Stadanlick J., Nunes F.A., Alter H.J., and Chang K.M. Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection. Hepatology 38 6 (2003) 1437-1448
-
(2003)
Hepatology
, vol.38
, Issue.6
, pp. 1437-1448
-
-
Sugimoto, K.1
Ikeda, F.2
Stadanlick, J.3
Nunes, F.A.4
Alter, H.J.5
Chang, K.M.6
-
90
-
-
7044247947
-
An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection
-
Cabrera R., Tu Z., Xu Y., Firpi R.J., Rosen H.R., Liu C., and Nelson D.R. An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection. Hepatology 40 5 (2004) 1062-1071
-
(2004)
Hepatology
, vol.40
, Issue.5
, pp. 1062-1071
-
-
Cabrera, R.1
Tu, Z.2
Xu, Y.3
Firpi, R.J.4
Rosen, H.R.5
Liu, C.6
Nelson, D.R.7
-
91
-
-
19944370822
-
T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection
-
Boettler T., Spangenberg H.C., Neumann-Haefelin C., Panther E., Urbani S., Ferrari C., Blum H.E., von Weizsäcker F., and Thimme R. T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection. J. Virol. 79 12 (2005) 7860-7867
-
(2005)
J. Virol.
, vol.79
, Issue.12
, pp. 7860-7867
-
-
Boettler, T.1
Spangenberg, H.C.2
Neumann-Haefelin, C.3
Panther, E.4
Urbani, S.5
Ferrari, C.6
Blum, H.E.7
von Weizsäcker, F.8
Thimme, R.9
-
92
-
-
16844378685
-
Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma
-
Ormandy L.A., Hillemann T., Wedemeyer H., and Manns M.P. Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma. Cancer Res. 65 6 (2005) 2457-2464
-
(2005)
Cancer Res.
, vol.65
, Issue.6
, pp. 2457-2464
-
-
Ormandy, L.A.1
Hillemann, T.2
Wedemeyer, H.3
Manns, M.P.4
-
93
-
-
1642286866
-
Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: the role of the virus
-
Accapezzato D., Francavilla V., Rawson P., Cerino A., Cividini A., Mondelli M.U., and Barnaba V. Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: the role of the virus. Eur. J. Immunol. 34 2 (2004) 438-446
-
(2004)
Eur. J. Immunol.
, vol.34
, Issue.2
, pp. 438-446
-
-
Accapezzato, D.1
Francavilla, V.2
Rawson, P.3
Cerino, A.4
Cividini, A.5
Mondelli, M.U.6
Barnaba, V.7
-
94
-
-
0037099719
-
Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells
-
J onuleit H., Schmitt E., Kakirman H., Stassen M., Knop J., and Enk A.H. Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells. J. Exp. Med. 196 2 (2002) 255-260
-
(2002)
J. Exp. Med.
, vol.196
, Issue.2
, pp. 255-260
-
-
J onuleit, H.1
Schmitt, E.2
Kakirman, H.3
Stassen, M.4
Knop, J.5
Enk, A.H.6
-
95
-
-
0037099733
-
Human CD4(+)CD25(+) regulatory, contact dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]
-
Dieckmann D., Bruett C.H., Ploettner H., Lutz M.B., and Schuler G. Human CD4(+)CD25(+) regulatory, contact dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. J. Exp. Med. 196 2 (2002) 247-253
-
(2002)
J. Exp. Med.
, vol.196
, Issue.2
, pp. 247-253
-
-
Dieckmann, D.1
Bruett, C.H.2
Ploettner, H.3
Lutz, M.B.4
Schuler, G.5
-
96
-
-
0033063046
-
Serum levels of cytokines in hepatitis C-related liver disease: a longitudinal study
-
Huang Y.S., Hwang S.J., Chan C.Y., Wu J.C., Chao Y., Chang F.Y., and Lee S.D. Serum levels of cytokines in hepatitis C-related liver disease: a longitudinal study. Zhonghua Yi Xue Za Zhi (Taipei) 62 6 (1999) 327-333
-
(1999)
Zhonghua Yi Xue Za Zhi (Taipei)
, vol.62
, Issue.6
, pp. 327-333
-
-
Huang, Y.S.1
Hwang, S.J.2
Chan, C.Y.3
Wu, J.C.4
Chao, Y.5
Chang, F.Y.6
Lee, S.D.7
-
97
-
-
0030770259
-
Serum levels of IL-10, IL-15 and soluble tumour necrosis factor-(TNF-alpha) receptors in type C chronic liver disease
-
Kakumu S., Okumura A., Ishikawa T., Yano M., Enomoto A., Nishimura H., Yoshioka K., and Yoshika Y. Serum levels of IL-10, IL-15 and soluble tumour necrosis factor-(TNF-alpha) receptors in type C chronic liver disease. Clin. Exp. Immunol. 109 3 (1997) 458-463
-
(1997)
Clin. Exp. Immunol.
, vol.109
, Issue.3
, pp. 458-463
-
-
Kakumu, S.1
Okumura, A.2
Ishikawa, T.3
Yano, M.4
Enomoto, A.5
Nishimura, H.6
Yoshioka, K.7
Yoshika, Y.8
-
98
-
-
0037015951
-
Expression of interleukin-18, interferon-gamma and interleukin-10 in hepatocellular carcinoma
-
Chia C.S., Ban K., Ithnin H., Singh H., Krishnan R., Mokhtar S., Malihan N., and Seow H.F. Expression of interleukin-18, interferon-gamma and interleukin-10 in hepatocellular carcinoma. Immunol. Lett. 84 3 (2002) 163-172
-
(2002)
Immunol. Lett.
, vol.84
, Issue.3
, pp. 163-172
-
-
Chia, C.S.1
Ban, K.2
Ithnin, H.3
Singh, H.4
Krishnan, R.5
Mokhtar, S.6
Malihan, N.7
Seow, H.F.8
-
99
-
-
0026770647
-
Preoperative and postoperative cytokines in patients with cancer
-
Nakazaki H. Preoperative and postoperative cytokines in patients with cancer. Cancer 70 3 (1992) 709-713
-
(1992)
Cancer
, vol.70
, Issue.3
, pp. 709-713
-
-
Nakazaki, H.1
-
100
-
-
0033035787
-
Secretion of acute-phase proteins before and after hepatocellular carcinoma resection
-
Hu R.H., Lee P.H., and Yu S.C. Secretion of acute-phase proteins before and after hepatocellular carcinoma resection. J. Formos Med. Assoc. 98 2 (1999) 85-91
-
(1999)
J. Formos Med. Assoc.
, vol.98
, Issue.2
, pp. 85-91
-
-
Hu, R.H.1
Lee, P.H.2
Yu, S.C.3
-
101
-
-
12244250729
-
Cytokine, infiltrating macrophage and T cell-mediated response to development of primary and secondary human liver cancer
-
Bortolami M., Venturi C., Giacomelli L., Scalerta R., Bacchetti S., Marino F., Floreani A., Lise M., Naccarato R., and Farinati F. Cytokine, infiltrating macrophage and T cell-mediated response to development of primary and secondary human liver cancer. Dig. Liver Dis. 34 11 (2002) 794-801
-
(2002)
Dig. Liver Dis.
, vol.34
, Issue.11
, pp. 794-801
-
-
Bortolami, M.1
Venturi, C.2
Giacomelli, L.3
Scalerta, R.4
Bacchetti, S.5
Marino, F.6
Floreani, A.7
Lise, M.8
Naccarato, R.9
Farinati, F.10
-
102
-
-
30444448077
-
Cytokine profile in Egyptian hepatitis C virus genotype-4 in relation to liver disease progression
-
Zekri A.R., Ashour M.S., Hassan A., Alam El-Din H.M., El Shehaby A.M., and Abu-Shady M.A. Cytokine profile in Egyptian hepatitis C virus genotype-4 in relation to liver disease progression. World J. Gastroenterol. 11 42 (2005) 6624-6630
-
(2005)
World J. Gastroenterol.
, vol.11
, Issue.42
, pp. 6624-6630
-
-
Zekri, A.R.1
Ashour, M.S.2
Hassan, A.3
Alam El-Din, H.M.4
El Shehaby, A.M.5
Abu-Shady, M.A.6
-
103
-
-
0034083566
-
Regulation and antimetastatic functions of liver-associated natural killer cells
-
Wiltrout R.H. Regulation and antimetastatic functions of liver-associated natural killer cells. Immunol. Rev. 174 (2000) 63-76
-
(2000)
Immunol. Rev.
, vol.174
, pp. 63-76
-
-
Wiltrout, R.H.1
-
104
-
-
3142687525
-
Production of profibrotic cytokines by invariant NKT cells characterizes cirrhosis progression in chronic viral hepatitis
-
De Lalla C., Galli G., Aldrighetti L., Romeo R., Mariani M., Monno A., Nuti S., Colombo M., Callea F., Porcelli S.A., Panina-Bordignon P., Abrignani S., Casorati G., and Dellabona P. Production of profibrotic cytokines by invariant NKT cells characterizes cirrhosis progression in chronic viral hepatitis. J. Immunol. 173 2 (2004) 1417-1425
-
(2004)
J. Immunol.
, vol.173
, Issue.2
, pp. 1417-1425
-
-
De Lalla, C.1
Galli, G.2
Aldrighetti, L.3
Romeo, R.4
Mariani, M.5
Monno, A.6
Nuti, S.7
Colombo, M.8
Callea, F.9
Porcelli, S.A.10
Panina-Bordignon, P.11
Abrignani, S.12
Casorati, G.13
Dellabona, P.14
-
105
-
-
0026486418
-
Intrahepatic cytotoxic T lymphocytes specific for hepatitis C virus in persons with chronic hepatitis [published erratum appears in J Immunol 150(6) (1993) 2563]
-
Koziel M.J., Dudley D., Wong J.T., Dienstag J., Houghton M., Ralston R., and Walker B.D. Intrahepatic cytotoxic T lymphocytes specific for hepatitis C virus in persons with chronic hepatitis [published erratum appears in J Immunol 150(6) (1993) 2563]. J. Immunol. 149 (1992) 3339-3344
-
(1992)
J. Immunol.
, vol.149
, pp. 3339-3344
-
-
Koziel, M.J.1
Dudley, D.2
Wong, J.T.3
Dienstag, J.4
Houghton, M.5
Ralston, R.6
Walker, B.D.7
-
106
-
-
0027319205
-
Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD41 T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C
-
Minutello M.A., Pileri P., Unutmaz D., Censini S., Kuo G., Houghton M., Brunetto M.R., et al. Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD41 T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C. J. Exp. Med. 178 (1993) 17-25
-
(1993)
J. Exp. Med.
, vol.178
, pp. 17-25
-
-
Minutello, M.A.1
Pileri, P.2
Unutmaz, D.3
Censini, S.4
Kuo, G.5
Houghton, M.6
Brunetto, M.R.7
-
107
-
-
0028851607
-
T-cell-mediated autologous hepatocytotoxicity in patients with chronic hepatitis C virus infection
-
Liaw Y.F., Lee C.S., Tsai S.L., Liaw B.W., Chen T.C., Sheen I.S., and Chu C.M. T-cell-mediated autologous hepatocytotoxicity in patients with chronic hepatitis C virus infection. Hepatology 22 (1995) 1368-1373
-
(1995)
Hepatology
, vol.22
, pp. 1368-1373
-
-
Liaw, Y.F.1
Lee, C.S.2
Tsai, S.L.3
Liaw, B.W.4
Chen, T.C.5
Sheen, I.S.6
Chu, C.M.7
-
108
-
-
0029799762
-
Hepatitis C virus-associated fulminant hepatic failure
-
Farci P., Alter H.J., Shimoda A., Govindarajan S., Cheung L.C., Melpolder J.C., Sacher R.A., et al. Hepatitis C virus-associated fulminant hepatic failure. N. Engl. J. Med. 335 (1996) 631-634
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 631-634
-
-
Farci, P.1
Alter, H.J.2
Shimoda, A.3
Govindarajan, S.4
Cheung, L.C.5
Melpolder, J.C.6
Sacher, R.A.7
-
109
-
-
0027472018
-
Persistent hepatitis C viraemia without liver disease
-
Brillanti S., Foli M., Gaiani S., Masci C., Miglioli M., and Barbara L. Persistent hepatitis C viraemia without liver disease. Lancet 341 (1993) 464-465
-
(1993)
Lancet
, vol.341
, pp. 464-465
-
-
Brillanti, S.1
Foli, M.2
Gaiani, S.3
Masci, C.4
Miglioli, M.5
Barbara, L.6
-
111
-
-
0037274161
-
Does nitric oxide play a pathogenic role in hepatitis C virus infection?
-
Majano P.L., and Garcia-Monzon C. Does nitric oxide play a pathogenic role in hepatitis C virus infection?. Cell Death Differ. 10 Suppl. 1 (2003) S13-15
-
(2003)
Cell Death Differ.
, vol.10
, Issue.SUPPL. 1
-
-
Majano, P.L.1
Garcia-Monzon, C.2
-
112
-
-
0033863120
-
Activation of intracellular signaling by hepatitis B and C viruses: C-viral core is the most potent signal inducer
-
Kato N., Yoshida H., Ono-Nita S.K., Kato J., Goto T., Otsuka M., Lan K., Matsushima K., Shiratori Y., and Omata M. Activation of intracellular signaling by hepatitis B and C viruses: C-viral core is the most potent signal inducer. Hepatology 32 2 (2000) 405-412
-
(2000)
Hepatology
, vol.32
, Issue.2
, pp. 405-412
-
-
Kato, N.1
Yoshida, H.2
Ono-Nita, S.K.3
Kato, J.4
Goto, T.5
Otsuka, M.6
Lan, K.7
Matsushima, K.8
Shiratori, Y.9
Omata, M.10
-
113
-
-
1442306648
-
Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells
-
Choi J., Lee K.J., Zheng Y., Yamaga A.K., Lai M.M.C., and Ou J.H. Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells. Hepatology 39 (2004) 81-89
-
(2004)
Hepatology
, vol.39
, pp. 81-89
-
-
Choi, J.1
Lee, K.J.2
Zheng, Y.3
Yamaga, A.K.4
Lai, M.M.C.5
Ou, J.H.6
-
114
-
-
33645819203
-
Mechanisms of liver injury. III. Oxidative stress in the pathogenesis of hepatitis C virus
-
Choi J., and Ou J.H. Mechanisms of liver injury. III. Oxidative stress in the pathogenesis of hepatitis C virus. Am. J. Physiol. Gastrointest. Liver Physiol. 290 5 (2006) G847-851
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.290
, Issue.5
-
-
Choi, J.1
Ou, J.H.2
-
115
-
-
0346340016
-
Immunohistochemical evaluation of oxidative stress markers in chronic hepatitis C
-
Mahmood S., Kawanaka M., Kamei A., Izumi A., Nakata K., Niiyama G., Ikeda H., Hanano S., Suehiro M., Togawa K., and Yamada G. Immunohistochemical evaluation of oxidative stress markers in chronic hepatitis C. Antioxid. Redox Signal. 6 (2004) 19-24
-
(2004)
Antioxid. Redox Signal.
, vol.6
, pp. 19-24
-
-
Mahmood, S.1
Kawanaka, M.2
Kamei, A.3
Izumi, A.4
Nakata, K.5
Niiyama, G.6
Ikeda, H.7
Hanano, S.8
Suehiro, M.9
Togawa, K.10
Yamada, G.11
-
116
-
-
34250160595
-
Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma
-
Maki A., Kono H., Gupta M., Asakawa M., Suzuki T., Matsuda M., Fujii H., and Rusyn I. Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma. Ann. Surg. Oncol. 14 3 (2007) 1182-1190
-
(2007)
Ann. Surg. Oncol.
, vol.14
, Issue.3
, pp. 1182-1190
-
-
Maki, A.1
Kono, H.2
Gupta, M.3
Asakawa, M.4
Suzuki, T.5
Matsuda, M.6
Fujii, H.7
Rusyn, I.8
-
117
-
-
33646348166
-
Modulation of the transforming growth factor-beta signal transduction pathway by hepatitis C virus nonstructural 5A protein
-
Choi S.H., and Hwang S.B. Modulation of the transforming growth factor-beta signal transduction pathway by hepatitis C virus nonstructural 5A protein. J. Biol. Chem. 281 11 (2006) 7468-7478
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.11
, pp. 7468-7478
-
-
Choi, S.H.1
Hwang, S.B.2
-
118
-
-
33845635205
-
Pegylated arginine deiminase lowers hepatitis C viral titers and inhibits nitric oxide synthesis
-
Izzo F., Montella M., Orlando A.P., Nasti G., Beneduce G., Castello G., Cremona F., Ensor C.M., Holtzberg F.W., Bomalaski J.S., Clark M.A., Curley S.A., Orlando R., Scordino F., and Korba B.E. Pegylated arginine deiminase lowers hepatitis C viral titers and inhibits nitric oxide synthesis. J. Gastroenterol. Hepatol. 22 1 (2007) 86-91
-
(2007)
J. Gastroenterol. Hepatol.
, vol.22
, Issue.1
, pp. 86-91
-
-
Izzo, F.1
Montella, M.2
Orlando, A.P.3
Nasti, G.4
Beneduce, G.5
Castello, G.6
Cremona, F.7
Ensor, C.M.8
Holtzberg, F.W.9
Bomalaski, J.S.10
Clark, M.A.11
Curley, S.A.12
Orlando, R.13
Scordino, F.14
Korba, B.E.15
-
119
-
-
0035189701
-
Prognostic value of serum biological markers in patients with hepatocellular carcinoma
-
Parasole R., Izzo F., Perrone F., Pignata S., Galati M.G., Leonardi E., Castiglione F., Orlando R., Castello G., Esposito G., Gallo C., and Daniele B. Prognostic value of serum biological markers in patients with hepatocellular carcinoma. Clin. Cancer Res. 7 11 (2001) 3504-3509
-
(2001)
Clin. Cancer Res.
, vol.7
, Issue.11
, pp. 3504-3509
-
-
Parasole, R.1
Izzo, F.2
Perrone, F.3
Pignata, S.4
Galati, M.G.5
Leonardi, E.6
Castiglione, F.7
Orlando, R.8
Castello, G.9
Esposito, G.10
Gallo, C.11
Daniele, B.12
-
120
-
-
0032958169
-
Soluble interleukin-2 receptor levels in hepatocellular cancer: a more sensitive marker than alfa fetoprotein
-
Comment in: Ann Surg Oncol 6(2) 133-134
-
Izzo F., Cremona F., Delrio P., Leonardi E., Castello G., Pignata S., Daniele B., and Curley S.A. Soluble interleukin-2 receptor levels in hepatocellular cancer: a more sensitive marker than alfa fetoprotein. Ann. Surg. Oncol. 6 2 (1999) 178-185 Comment in: Ann Surg Oncol 6(2) 133-134
-
(1999)
Ann. Surg. Oncol.
, vol.6
, Issue.2
, pp. 178-185
-
-
Izzo, F.1
Cremona, F.2
Delrio, P.3
Leonardi, E.4
Castello, G.5
Pignata, S.6
Daniele, B.7
Curley, S.A.8
-
121
-
-
0031958419
-
Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection
-
Polyak S.J., McArdle S., Liu S.L., Sullivan D.G., Chung M., Hofgärtner W.T., Carithers Jr. R.L., McMahon B.J., Mullins J.I., Corey L., and Gretch D.R. Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection. J. Virol. 72 5 (1998) 4288-4296
-
(1998)
J. Virol.
, vol.72
, Issue.5
, pp. 4288-4296
-
-
Polyak, S.J.1
McArdle, S.2
Liu, S.L.3
Sullivan, D.G.4
Chung, M.5
Hofgärtner, W.T.6
Carithers Jr., R.L.7
McMahon, B.J.8
Mullins, J.I.9
Corey, L.10
Gretch, D.R.11
-
122
-
-
0034646996
-
The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies
-
Farci P., Shimoda A., Coiana A., Diaz G., Peddis G., Melpolder J.C., Strazzera A., Chien D.Y., Munoz S.J., Balestrieri A., Purcell R.H., and Alter H.J. The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies. Science 288 5464 (2000) 339-344
-
(2000)
Science
, vol.288
, Issue.5464
, pp. 339-344
-
-
Farci, P.1
Shimoda, A.2
Coiana, A.3
Diaz, G.4
Peddis, G.5
Melpolder, J.C.6
Strazzera, A.7
Chien, D.Y.8
Munoz, S.J.9
Balestrieri, A.10
Purcell, R.H.11
Alter, H.J.12
-
123
-
-
59249106268
-
Diagnosis and management of chronic viral hepatitis: antigens, antibodies and viral genomes
-
Chevaliez S., and Pawlotsky J.M. Diagnosis and management of chronic viral hepatitis: antigens, antibodies and viral genomes. Best Pract. Res. Clin. Gastroenterol. 6 (2008) 1031-1048
-
(2008)
Best Pract. Res. Clin. Gastroenterol.
, vol.6
, pp. 1031-1048
-
-
Chevaliez, S.1
Pawlotsky, J.M.2
-
124
-
-
0035121503
-
Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection
-
Bain C., Fatmi A., Zoulim F., Zarski J.P., Trépo C., and Inchauspé G. Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection. Gastroenterology 120 2 (2001) 512-524
-
(2001)
Gastroenterology
, vol.120
, Issue.2
, pp. 512-524
-
-
Bain, C.1
Fatmi, A.2
Zoulim, F.3
Zarski, J.P.4
Trépo, C.5
Inchauspé, G.6
-
125
-
-
20044384191
-
Plasmacytoid dendritic cells in acute and chronic hepatitis C virus infection
-
Ulsenheimer A., Gerlach J.T., Jung M.C., Gruener N., Wächtler M., Backmund M., Santantonio T., Schraut W., Heeg M.H., Schirren C.A., Zachoval R., Pape G.R., and Diepolder H.M. Plasmacytoid dendritic cells in acute and chronic hepatitis C virus infection. Hepatology 41 3 (2005) 643-651
-
(2005)
Hepatology
, vol.41
, Issue.3
, pp. 643-651
-
-
Ulsenheimer, A.1
Gerlach, J.T.2
Jung, M.C.3
Gruener, N.4
Wächtler, M.5
Backmund, M.6
Santantonio, T.7
Schraut, W.8
Heeg, M.H.9
Schirren, C.A.10
Zachoval, R.11
Pape, G.R.12
Diepolder, H.M.13
-
126
-
-
4043148744
-
Hepatitis C virus mutation affects proteasomal epitope processing
-
Seifert U., Liermann H., Racanelli V., Halenius A., Wiese M., Wedemeyer H., Ruppert T., Rispeter K., Henklein P., Sijts A., Hengel H., Kloetzel P.M., and Rehermann B. Hepatitis C virus mutation affects proteasomal epitope processing. J. Clin. Invest. 114 2 (2004) 250-259
-
(2004)
J. Clin. Invest.
, vol.114
, Issue.2
, pp. 250-259
-
-
Seifert, U.1
Liermann, H.2
Racanelli, V.3
Halenius, A.4
Wiese, M.5
Wedemeyer, H.6
Ruppert, T.7
Rispeter, K.8
Henklein, P.9
Sijts, A.10
Hengel, H.11
Kloetzel, P.M.12
Rehermann, B.13
-
127
-
-
0037033359
-
Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein
-
Crotta S., Stilla A., Wack A., D'Andrea A., Nuti S., D'Oro U., Mosca M., Filliponi F., Brunetto R.M., Bonino F., Abrignani S., and Valiante N.M. Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein. J. Exp. Med. 195 1 (2002) 35-41
-
(2002)
J. Exp. Med.
, vol.195
, Issue.1
, pp. 35-41
-
-
Crotta, S.1
Stilla, A.2
Wack, A.3
D'Andrea, A.4
Nuti, S.5
D'Oro, U.6
Mosca, M.7
Filliponi, F.8
Brunetto, R.M.9
Bonino, F.10
Abrignani, S.11
Valiante, N.M.12
-
128
-
-
0036788253
-
Peg-interferon alone or with ribavirin enhances HCV-specific CD4 T helper 1 responses in patients with chronic hepatitis C
-
Kamal S.M., Fehr J., Roesler B., Peters T., and Rasenack J.W. Peg-interferon alone or with ribavirin enhances HCV-specific CD4 T helper 1 responses in patients with chronic hepatitis C. Gastroenterology 123 4 (2002) 1070-1083
-
(2002)
Gastroenterology
, vol.123
, Issue.4
, pp. 1070-1083
-
-
Kamal, S.M.1
Fehr, J.2
Roesler, B.3
Peters, T.4
Rasenack, J.W.5
-
129
-
-
0036727325
-
The dynamics of T-lymphocyte responses during combination therapy for chronic hepatitis C virus infection
-
Barnes E., Harcourt G., Brown D., Lucas M., Phillips R., Dusheiko G., and Klenerman P. The dynamics of T-lymphocyte responses during combination therapy for chronic hepatitis C virus infection. Hepatology 36 3 (2002) 743-754
-
(2002)
Hepatology
, vol.36
, Issue.3
, pp. 743-754
-
-
Barnes, E.1
Harcourt, G.2
Brown, D.3
Lucas, M.4
Phillips, R.5
Dusheiko, G.6
Klenerman, P.7
-
130
-
-
0036237490
-
Abnormal priming of CD4(+) T cells by dendritic cells expressing hepatitis C virus core and E1 proteins
-
Erratum in: J Virol. 138(1) (2004) 193
-
Sarobe P., Lasarte J.J., Casares N., López-Díaz de Cerio A., Baixeras E., Labarga P., García N., Borrás-Cuesta F., and Prieto J. Abnormal priming of CD4(+) T cells by dendritic cells expressing hepatitis C virus core and E1 proteins. J. Virol. 76 10 (2002) 5062-5070 Erratum in: J Virol. 138(1) (2004) 193
-
(2002)
J. Virol.
, vol.76
, Issue.10
, pp. 5062-5070
-
-
Sarobe, P.1
Lasarte, J.J.2
Casares, N.3
López-Díaz de Cerio, A.4
Baixeras, E.5
Labarga, P.6
García, N.7
Borrás-Cuesta, F.8
Prieto, J.9
-
131
-
-
0037851770
-
Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation
-
Dolganiuc A., Kodys K., Kopasz A., Marshall C., Do T., Romics Jr. L., Mandrekar P., Zapp M., and Szabo G. Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation. J. Immunol. 170 11 (2003) 5615-5624
-
(2003)
J. Immunol.
, vol.170
, Issue.11
, pp. 5615-5624
-
-
Dolganiuc, A.1
Kodys, K.2
Kopasz, A.3
Marshall, C.4
Do, T.5
Romics Jr., L.6
Mandrekar, P.7
Zapp, M.8
Szabo, G.9
-
132
-
-
0347382454
-
Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes
-
Brady M.T., MacDonald A.J., Rowan A.G., and Mills K.H. Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes. Eur. J. Immunol. 33 12 (2003) 3448-3457
-
(2003)
Eur. J. Immunol.
, vol.33
, Issue.12
, pp. 3448-3457
-
-
Brady, M.T.1
MacDonald, A.J.2
Rowan, A.G.3
Mills, K.H.4
-
133
-
-
0345742565
-
CD81 is required for hepatitis C virus glycoprotein mediated viral infection
-
Zhang J., Randall G., Higginbottom A., Monk P., Rice C.M., and McKeating J.A. CD81 is required for hepatitis C virus glycoprotein mediated viral infection. J. Virol. 78 3 (2004) 1448-1455
-
(2004)
J. Virol.
, vol.78
, Issue.3
, pp. 1448-1455
-
-
Zhang, J.1
Randall, G.2
Higginbottom, A.3
Monk, P.4
Rice, C.M.5
McKeating, J.A.6
-
134
-
-
1642384546
-
Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms
-
Francavilla V., Accapezzato D., De Salvo M., Rawson P., Cosimi O., Lipp M., Cerino A., Cividini A., Mondelli M.U., and Barnaba V. Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms. Eur. J. Immunol. 34 2 (2004) 427-437
-
(2004)
Eur. J. Immunol.
, vol.34
, Issue.2
, pp. 427-437
-
-
Francavilla, V.1
Accapezzato, D.2
De Salvo, M.3
Rawson, P.4
Cosimi, O.5
Lipp, M.6
Cerino, A.7
Cividini, A.8
Mondelli, M.U.9
Barnaba, V.10
-
135
-
-
1642484987
-
Pervasive influence of hepatitis C virus on the phenotype of antiviral CD8+ T cells
-
Lucas M., Vargas-Cuero A.L., Lauer G.M., Barnes E., Willberg C.B., Semmo N., Walker B.D., Phillips R., and Klenerman P. Pervasive influence of hepatitis C virus on the phenotype of antiviral CD8+ T cells. J. Immunol. 172 3 (2004) 1744-1753
-
(2004)
J. Immunol.
, vol.172
, Issue.3
, pp. 1744-1753
-
-
Lucas, M.1
Vargas-Cuero, A.L.2
Lauer, G.M.3
Barnes, E.4
Willberg, C.B.5
Semmo, N.6
Walker, B.D.7
Phillips, R.8
Klenerman, P.9
-
136
-
-
0037270978
-
Hepatic T cells and liver tolerance
-
Crispe I.N. Hepatic T cells and liver tolerance. Nat. Rev. Immunol. 3 1 (2003) 51-62
-
(2003)
Nat. Rev. Immunol.
, vol.3
, Issue.1
, pp. 51-62
-
-
Crispe, I.N.1
-
137
-
-
0037302569
-
Dendritic cells and immune regulation in the liver
-
Lau A.H., and Thomson A.W. Dendritic cells and immune regulation in the liver. Gut 52 2 (2003) 307-314
-
(2003)
Gut
, vol.52
, Issue.2
, pp. 307-314
-
-
Lau, A.H.1
Thomson, A.W.2
-
138
-
-
2442484053
-
Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22 (2004) 531-562
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
140
-
-
0026767691
-
Lack of protective immunity against reinfection with hepatitis C virus
-
Farci P., Alter H.J., Govindarajan S., Wong D.C., Engle R., Lesniewski R.R., Mushahwar I.K., Desai S.M., Miller R.H., Ogata N., et al. Lack of protective immunity against reinfection with hepatitis C virus. Science 258 (1992) 135-140
-
(1992)
Science
, vol.258
, pp. 135-140
-
-
Farci, P.1
Alter, H.J.2
Govindarajan, S.3
Wong, D.C.4
Engle, R.5
Lesniewski, R.R.6
Mushahwar, I.K.7
Desai, S.M.8
Miller, R.H.9
Ogata, N.10
-
141
-
-
37249079121
-
HCV core protein interaction with gC1q receptor inhibits TH1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production
-
Waggoner S.N., Hall C.H., and Hahn Y.S. HCV core protein interaction with gC1q receptor inhibits TH1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production. J. Leukoc. Biol. 82 (2007) 1407-1419
-
(2007)
J. Leukoc. Biol.
, vol.82
, pp. 1407-1419
-
-
Waggoner, S.N.1
Hall, C.H.2
Hahn, Y.S.3
-
142
-
-
0033120555
-
Mutations in immunodominant T-cell epitopes derived from the nonstructural 3 protein of hepatitis C virus have the potential for generating escape variants that may have important consequences for T-cell recognition
-
Wang H., and Eckels D.D. Mutations in immunodominant T-cell epitopes derived from the nonstructural 3 protein of hepatitis C virus have the potential for generating escape variants that may have important consequences for T-cell recognition. J. Immunol. 162 (1999) 4177-4183
-
(1999)
J. Immunol.
, vol.162
, pp. 4177-4183
-
-
Wang, H.1
Eckels, D.D.2
-
143
-
-
0038374730
-
Detection of functionally altered hepatitis C virus-specific CD4 T cells in acute and chronic hepatitis C
-
Ulsenheimer A., Gerlach J.T., Gruener N.H., et al. Detection of functionally altered hepatitis C virus-specific CD4 T cells in acute and chronic hepatitis C. Hepatology 37 (2003) 1189-1198
-
(2003)
Hepatology
, vol.37
, pp. 1189-1198
-
-
Ulsenheimer, A.1
Gerlach, J.T.2
Gruener, N.H.3
-
144
-
-
0038345165
-
Modulation of the peripheral T-cell response by CD4 mutants of hepatitis C virus: transition from a TH1 to a TH2 response
-
Wang J.H., Layden T.J., and Eckels D.D. Modulation of the peripheral T-cell response by CD4 mutants of hepatitis C virus: transition from a TH1 to a TH2 response. Hum. Immunol. 64 (2003) 662-673
-
(2003)
Hum. Immunol.
, vol.64
, pp. 662-673
-
-
Wang, J.H.1
Layden, T.J.2
Eckels, D.D.3
-
145
-
-
0037105567
-
Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection
-
Wedemeyer H., He X.S., Nascimbeni M., Davis A.R., Greenberg H.B., Hoofnagle J.H., Liang T.J., Alter H., and Rehermann B. Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. J. Immunol. 169 (2002) 3447-3458
-
(2002)
J. Immunol.
, vol.169
, pp. 3447-3458
-
-
Wedemeyer, H.1
He, X.S.2
Nascimbeni, M.3
Davis, A.R.4
Greenberg, H.B.5
Hoofnagle, J.H.6
Liang, T.J.7
Alter, H.8
Rehermann, B.9
-
146
-
-
33947421722
-
Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection
-
Penna A., Pilli M., Zerbini A., Orlandini A., Mezzadri S., Sacchelli L., Missale G., and Ferrari C. Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection. Hepatology 45 (2007) 588-601
-
(2007)
Hepatology
, vol.45
, pp. 588-601
-
-
Penna, A.1
Pilli, M.2
Zerbini, A.3
Orlandini, A.4
Mezzadri, S.5
Sacchelli, L.6
Missale, G.7
Ferrari, C.8
-
147
-
-
25844470442
-
Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection
-
Spangenberg H.C., Viazov S., Kersting N., Neumann-Haefelin C., McKinney D., Roggendorf M., von Weizsäcker F., Blum H.E., and Thimme R. Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection. Hepatology 42 (2005) 828-837
-
(2005)
Hepatology
, vol.42
, pp. 828-837
-
-
Spangenberg, H.C.1
Viazov, S.2
Kersting, N.3
Neumann-Haefelin, C.4
McKinney, D.5
Roggendorf, M.6
von Weizsäcker, F.7
Blum, H.E.8
Thimme, R.9
-
148
-
-
46249090636
-
Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection
-
Neumann-Haefelin C., Timm J., Spangenberg H.C., Wischniowski N., Nazarova N., Kersting N., Roggendorf M., Allen T.M., Blum H.E., and Thimme R. Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection. Hepatology 47 (2008) 1824-1836
-
(2008)
Hepatology
, vol.47
, pp. 1824-1836
-
-
Neumann-Haefelin, C.1
Timm, J.2
Spangenberg, H.C.3
Wischniowski, N.4
Nazarova, N.5
Kersting, N.6
Roggendorf, M.7
Allen, T.M.8
Blum, H.E.9
Thimme, R.10
-
149
-
-
0033458948
-
Diagnostic tests for hepatitis C
-
Pawlotsky J.M. Diagnostic tests for hepatitis C. J. Hepatol. 31 Suppl. 1 (1999) 71-79
-
(1999)
J. Hepatol.
, vol.31
, Issue.SUPPL. 1
, pp. 71-79
-
-
Pawlotsky, J.M.1
-
150
-
-
0033690901
-
Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation
-
Kittlesen D.J., Chianese-Bullock K.A., Yao Z.Q., Braciale T.J., and Hahn Y.S. Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation. J. Clin. Invest. 106 10 (2000) 1239-1249
-
(2000)
J. Clin. Invest.
, vol.106
, Issue.10
, pp. 1239-1249
-
-
Kittlesen, D.J.1
Chianese-Bullock, K.A.2
Yao, Z.Q.3
Braciale, T.J.4
Hahn, Y.S.5
-
151
-
-
14944375587
-
Immunology of hepatitis B virus and hepatitis C virus infection
-
Rehermann B., and Nascimbeni M. Immunology of hepatitis B virus and hepatitis C virus infection. Nat. Rev. Immunol. 5 3 (2005 Mar) 215-229
-
(2005)
Nat. Rev. Immunol.
, vol.5
, Issue.3
, pp. 215-229
-
-
Rehermann, B.1
Nascimbeni, M.2
-
152
-
-
0036236538
-
Role of primary intrahepatic T-cell activation in the "liver tolerance effect"
-
Bertolino P., McCaughan G.W., and Bowen D.G. Role of primary intrahepatic T-cell activation in the "liver tolerance effect". Immunol. Cell Biol. 80 1 (2002 Feb) 84-92
-
(2002)
Immunol. Cell Biol.
, vol.80
, Issue.1
, pp. 84-92
-
-
Bertolino, P.1
McCaughan, G.W.2
Bowen, D.G.3
-
153
-
-
19944366276
-
Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection
-
Rushbrook S.M., Ward S.M., Unitt E., Vowler S.L., Lucas M., Klenerman P., and Alexander G.J. Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection. J. Virol. 79 12 (2005) 7852-7859
-
(2005)
J. Virol.
, vol.79
, Issue.12
, pp. 7852-7859
-
-
Rushbrook, S.M.1
Ward, S.M.2
Unitt, E.3
Vowler, S.L.4
Lucas, M.5
Klenerman, P.6
Alexander, G.J.7
|