Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection

Journal of Experimental Medicine

Volumn 197, Issue 12, 2003, Pages 1645-1655

  Shoukry, Naglaa H ^a   Grakoui, Arash ^b   Houghton, Michael ^c   Chien, David Y ^c   Ghrayeb, John ^d   Reimann, Keith A ^e   Walker, Christopher M ^a,f  

^a THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

^d CENTOCOR INC   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Hepatitis C; Immunologic memory; Liver diseases; T lymphocytes; Viral hepatitis

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; HEPATITIS C VIRUS PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DEPENDENT LYMPHOCYTOTOXICITY; ANTIBODY TITER; ARTICLE; CHIMPANZEE; CHRONIC HEPATITIS; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; DISEASE CONTROL; DISEASE COURSE; FOLLOW UP; HELPER CELL; HEPATITIS C; HEPATITIS C VIRUS; IMMUNE RESPONSE; MEMORY CELL; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; REINFECTION; T LYMPHOCYTE SUBPOPULATION; VIREMIA; VIRUS CLEARANCE; VIRUS CONTROL; VIRUS REPLICATION; VIRUS SPECIFIC CYTOLYTIC ACTIVITY;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES; HEPACIVIRUS; HEPATITIS C; HUMANS; IMMUNOLOGIC MEMORY; PAN TROGLODYTES; TIME FACTORS; VIRUS REPLICATION;

EID: 0038543543     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20030239     Document Type: Article

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