Minimal-length short hairpin RNAs: The relationship of structure and RNAi activity

RNA

Volumn 16, Issue 1, 2010, Pages 106-117

  Ge, Qing ^a,c   Ilves, Heini ^a   Dallas, Anne ^a   Kumar, Pavan ^a   Shorenstein, Joshua ^a   Kazakov, Sergei A ^a   Johnston, Brian H ^a,b  

^a SomaGenics Inc   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Dicer; Immunostimulatory; shRNA; Small hairpin RNA; sshRNA; Stem loop

Indexed keywords

COMPLEMENTARY RNA; DICER; NUCLEOTIDE; SHORT HAIRPIN RNA; DEAD BOX PROTEIN; DICER1 PROTEIN, HUMAN; INTERFERON; RIBONUCLEASE III; SMALL INTERFERING RNA;

ARTICLE; CONTROLLED STUDY; DIMERIZATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; REPORTER GENE; RNA INTERFERENCE; RNA STRUCTURE; RNA TRANSCRIPTION; STRUCTURE ACTIVITY RELATION; BASE MISPAIRING; BIOLOGICAL MODEL; CELL CULTURE; CHEMISTRY; CONFORMATION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PRODUCTIVITY;

BASE PAIR MISMATCH; BASE SEQUENCE; CATALYTIC DOMAIN; CELLS, CULTURED; DEAD-BOX RNA HELICASES; DIMERIZATION; EFFICIENCY; HUMANS; INTERFERONS; MODELS, BIOLOGICAL; NUCLEIC ACID CONFORMATION; RIBONUCLEASE III; RNA INTERFERENCE; RNA, SMALL INTERFERING; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 75649143739     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.1894510     Document Type: Article

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