-
1
-
-
0024452528
-
The pharmacology of dichloroacetate
-
Stacpoole PW: The pharmacology of dichloroacetate. Metabolism 38: 1124-1144, 1989.
-
(1989)
Metabolism
, vol.38
, pp. 1124-1144
-
-
Stacpoole, P.W.1
-
2
-
-
0020593706
-
Treatment of lactic acidosis with dichloroacetate
-
Stacpoole PW, Harman EM, Curry SH, Baumgartner TG and Misbin RI: Treatment of lactic acidosis with dichloroacetate. New Eng J Med 309: 390-396, 1983.
-
(1983)
New Eng J Med
, vol.309
, pp. 390-396
-
-
Stacpoole, P.W.1
Harman, E.M.2
Curry, S.H.3
Baumgartner, T.G.4
Misbin, R.I.5
-
3
-
-
4744357401
-
Chronic treatment of mitochondrial disease patients with dichloroacetate
-
Barshop BA, Naviaux RK, McGowan KA, Levine F, Nyhan WL, Loupis-Geller A and Haas RH: Chronic treatment of mitochondrial disease patients with dichloroacetate. Mol Genet Metab 83: 138-149, 2004
-
(2004)
Mol Genet Metab
, vol.83
, pp. 138-149
-
-
Barshop, B.A.1
Naviaux, R.K.2
McGowan, K.A.3
Levine, F.4
Nyhan, W.L.5
Loupis-Geller, A.6
Haas, R.H.7
-
4
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cell hypoxia
-
Kim J-W, Tchernyshyov I, Semenza GL and Dang CV: HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cell hypoxia. Cell Metab 3: 177-185, 2006.
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.-W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
5
-
-
33644622570
-
HIF-1-mediates adaption to hypoxia by actively down-regulating mitochondrial oxygen consumption
-
Papandreou I, Cairns RA, Fontana L, Lim AL and Denko NC: HIF-1-mediates adaption to hypoxia by actively down-regulating mitochondrial oxygen consumption. Cell Metab 3: 187-197, 2006.
-
(2006)
Cell Metab
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
6
-
-
33846002728
-
+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth Cancer Cell 11: 37-51, 2007.
-
(2007)
Cancer Cell
, vol.11
, pp. 37-51
-
-
Bonnet, S.1
Archer, S.L.2
Allalunis-Turner, J.3
Harmony, A.4
Beaulieu, C.5
Thompson, R.6
Lee, C.T.7
Lopaschuk, G.D.8
Puttagunta, L.9
Bonnet, S.10
Harry, G.11
Hashimoto, K.12
Porter, C.J.13
Andrade, M.A.14
Thebaud, B.15
Michelakis, E.D.16
-
8
-
-
0030614893
-
2 gradients in solid tumors in vivo: High resolution measurements reveal a lack of correlation
-
2 gradients in solid tumors in vivo: High resolution measurements reveal a lack of correlation. Nat Med 3: 177-182, 1997.
-
(1997)
Nat Med
, vol.3
, pp. 177-182
-
-
Helmlinger, G.1
Yuan, F.2
Dellian, M.3
Jain, R.K.4
-
9
-
-
0037490210
-
Hypoxia-inducible factors and its biomedical relevance
-
Huang LE and Bunn HF: Hypoxia-inducible factors and its biomedical relevance. JBC 278: 19575-19578, 2003.
-
(2003)
JBC
, vol.278
, pp. 19575-19578
-
-
Huang, L.E.1
Bunn, H.F.2
-
10
-
-
51049113430
-
Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity
-
Sullivan R, Pare GC, Frederiksen LJ, Semenza GL and Graham CH: Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity. Mol Can Ther 7: 1961-1973, 2008.
-
(2008)
Mol Can Ther
, vol.7
, pp. 1961-1973
-
-
Sullivan, R.1
Pare, G.C.2
Frederiksen, L.J.3
Semenza, G.L.4
Graham, C.H.5
-
11
-
-
75149171708
-
-
Norris BJ, Cramer MJ and Hirschel HD: Chapt 9, Growth of cell lines in bioreactors. In: Basic Methods in Antibody Production and Characterization. Heward GC and Bethell DR (eds.). Boca Rotan FL, USA, CRC Press, 2000.
-
Norris BJ, Cramer MJ and Hirschel HD: Chapt 9, Growth of cell lines in bioreactors. In: Basic Methods in Antibody Production and Characterization. Heward GC and Bethell DR (eds.). Boca Rotan FL, USA, CRC Press, 2000.
-
-
-
-
12
-
-
0002711621
-
-
2, Chemical, Biochemical and Physiologic Aspects, and, eds, Washington DC, NASA
-
2, Chemical, Biochemical and Physiologic Aspects. Forster RE, Edsall JT, Otis AB and Roughton FJW (eds.). Washington DC, NASA, 1969.
-
(1969)
Carbon dioxide, carbonic acid and bicarbonate ions: Physical properties and kinetics of conversion, p SP-188
-
-
Edsall, J.T.1
-
13
-
-
75149143798
-
Handbook of Chemistry and Physics, 72 nd, from 6-3 to 6-7
-
Lide DR ed, FL, U.S.A
-
Lide DR (ed.). Handbook of Chemistry and Physics, 72 nd, from 6-3 to 6-7, 1991-1992. CRC Press, Boca Rotan, FL, U.S.A.
-
(1991)
CRC Press, Boca Rotan
-
-
-
14
-
-
0344608877
-
Dominant-negative hypoxia-inducible factor-1A reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism
-
Chen J, Zhao S, Nakada K, Kuge Y, Tamaki N, Okada F, Wang J, Shindo M, Higashino F, Takeda K, Asaka M, Katoh H, Sugiyama T, Hosuo H and Kobayashi M: Dominant-negative hypoxia-inducible factor-1A reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism. Am J Path 162: 1283-1291, 2003.
-
(2003)
Am J Path
, vol.162
, pp. 1283-1291
-
-
Chen, J.1
Zhao, S.2
Nakada, K.3
Kuge, Y.4
Tamaki, N.5
Okada, F.6
Wang, J.7
Shindo, M.8
Higashino, F.9
Takeda, K.10
Asaka, M.11
Katoh, H.12
Sugiyama, T.13
Hosuo, H.14
Kobayashi, M.15
-
15
-
-
33745868751
-
Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis: Involvement of mitochondrial inhibition and p53 suppression
-
Wang J, Biju MP, Wang M-H, Wang M-H, Haaase VH and Dong Z: Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis: Involvement of mitochondrial inhibition and p53 suppression. J Am Soc Nephrol 17: 1875-1885, 2006.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1875-1885
-
-
Wang, J.1
Biju, M.P.2
Wang, M.-H.3
Wang, M.-H.4
Haaase, V.H.5
Dong, Z.6
-
16
-
-
55549109773
-
Dichloroacetate-induced modulation of cellular antioxidant enzyme activities and glutathione level in the J774A.1 cells
-
Hassoun EA and Mehta J: Dichloroacetate-induced modulation of cellular antioxidant enzyme activities and glutathione level in the J774A.1 cells. Appl Toxicol 28: 931-937, 2008.
-
(2008)
Appl Toxicol
, vol.28
, pp. 931-937
-
-
Hassoun, E.A.1
Mehta, J.2
-
17
-
-
33845921375
-
The proliferative response of HeLa cells to 2-deoxy-D-glucose under hypoxic or anoxic conditions: An analogue for studying some properties of in vivo solid cancers
-
Anderson KM, Tsui P, Guinan P and Rubenstein M: The proliferative response of HeLa cells to 2-deoxy-D-glucose under hypoxic or anoxic conditions: An analogue for studying some properties of in vivo solid cancers. Anticancer Res 26: 4155-4162, 2006.
-
(2006)
Anticancer Res
, vol.26
, pp. 4155-4162
-
-
Anderson, K.M.1
Tsui, P.2
Guinan, P.3
Rubenstein, M.4
-
18
-
-
34250753161
-
Cell death modalities: Classification and pathophysiological implications
-
Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L and Koemer G: Cell death modalities: classification and pathophysiological implications. Cell Death Diff 14: 1237-1266, 2007.
-
(2007)
Cell Death Diff
, vol.14
, pp. 1237-1266
-
-
Galluzzi, L.1
Maiuri, M.C.2
Vitale, I.3
Zischka, H.4
Castedo, M.5
Zitvogel, L.6
Koemer, G.7
-
19
-
-
0010170555
-
Hypoxia induces DNA overreplication and enhances metaststic potential of murine tumor cells
-
Young SD, Marshall RS and Hill RP: Hypoxia induces DNA overreplication and enhances metaststic potential of murine tumor cells. Proc Nat Acad Sci USA 85: 9533-9537, 1988.
-
(1988)
Proc Nat Acad Sci USA
, vol.85
, pp. 9533-9537
-
-
Young, S.D.1
Marshall, R.S.2
Hill, R.P.3
-
20
-
-
34347387832
-
Restriction of DNA replication to the reductive phase of the metabolic cycle protects genome integrity
-
Chen Z, Odstrcil EA, Tu BP and McKnight SL: Restriction of DNA replication to the reductive phase of the metabolic cycle protects genome integrity. Science 316: 1916-1919, 2007.
-
(2007)
Science
, vol.316
, pp. 1916-1919
-
-
Chen, Z.1
Odstrcil, E.A.2
Tu, B.P.3
McKnight, S.L.4
-
21
-
-
33745149291
-
p53 regulates mitochondrial respiration
-
Matoba S, Kang J-G, Patino WD, Wragg A, Boehm M, Gavrilova O, Hurley PJ, Bunz F and Hwang PM: p53 regulates mitochondrial respiration. Science 312: 1650-1653, 2006.
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.-G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
22
-
-
65649117863
-
Hypoxia regulates human lung fibroblast proliferation via p53-dependent and -independent pathways
-
Mizuno S, Bogaard HJ, Voelkel NF, Umeda Y, Kadowaki M, Ameshima S, Miyamori I and Ishizaki T: Hypoxia regulates human lung fibroblast proliferation via p53-dependent and -independent pathways. Resp Res 10: 17-30, 2009.
-
(2009)
Resp Res
, vol.10
, pp. 17-30
-
-
Mizuno, S.1
Bogaard, H.J.2
Voelkel, N.F.3
Umeda, Y.4
Kadowaki, M.5
Ameshima, S.6
Miyamori, I.7
Ishizaki, T.8
-
23
-
-
0032720358
-
Effects of diisopropylamine dichloroacetate on proliferation and differentiation of normal human keratinocytes in vitro
-
Kitamura N, Ota Y and Mimura K: Effects of diisopropylamine dichloroacetate on proliferation and differentiation of normal human keratinocytes in vitro. Skin Pharm Physiol 12: 317-325, 1999.
-
(1999)
Skin Pharm Physiol
, vol.12
, pp. 317-325
-
-
Kitamura, N.1
Ota, Y.2
Mimura, K.3
-
24
-
-
13344262717
-
Dichloroacetate increases cell and antibody yields in hybridoma batch cultures of hybridoma cell lines
-
Murray K, Gull K and Dickson AJ: Dichloroacetate increases cell and antibody yields in hybridoma batch cultures of hybridoma cell lines. Biotech Bioeng 49: 377-382, 1996.
-
(1996)
Biotech Bioeng
, vol.49
, pp. 377-382
-
-
Murray, K.1
Gull, K.2
Dickson, A.J.3
-
25
-
-
0032103380
-
Dichloroacetate and trichloroacetate promote clonal expansion of anchorage-independent hepatocytes in vivo and in vitro
-
Stauberg AJ, Bull RJ and Thrall BD: Dichloroacetate and trichloroacetate promote clonal expansion of anchorage-independent hepatocytes in vivo and in vitro. Toxicol Appl Pharma 150: 287-294, 1998.
-
(1998)
Toxicol Appl Pharma
, vol.150
, pp. 287-294
-
-
Stauberg, A.J.1
Bull, R.J.2
Thrall, B.D.3
-
26
-
-
75149128448
-
-
Otterson GA, Wang L, Wu X, Duan W, Gao M, Karpenko MA and Villlalona-Caiero MA: Effect of dichloroacetate in combination with chemotherapy on human lung cancer cells. J Clin Oncol 26: abstr 14637, 2008.
-
Otterson GA, Wang L, Wu X, Duan W, Gao M, Karpenko MA and Villlalona-Caiero MA: Effect of dichloroacetate in combination with chemotherapy on human lung cancer cells. J Clin Oncol 26: abstr 14637, 2008.
-
-
-
-
27
-
-
44549083746
-
Dichloroacetate induces apoptosis in endometrial cancer cells
-
Wong JY, Huggins GS, Debidda M, Munshi NC and De Vivo I: Dichloroacetate induces apoptosis in endometrial cancer cells. Gynecol Oncol 109: 394-402, 2008.
-
(2008)
Gynecol Oncol
, vol.109
, pp. 394-402
-
-
Wong, J.Y.1
Huggins, G.S.2
Debidda, M.3
Munshi, N.C.4
De Vivo, I.5
-
28
-
-
48749093935
-
Dichloroacetate (DCA) sensitizes both wild-type and overexpressing BCL-2 prostate cells in vitro to involution
-
Cao W, Yacoub S, Shiverick KT, Namiki K, Sakai Y, Porvasnik S, Urbanek C and Rosser CJ: Dichloroacetate (DCA) sensitizes both wild-type and overexpressing BCL-2 prostate cells in vitro to involution. Prostate 68: 1223-1236, 2008.
-
(2008)
Prostate
, vol.68
, pp. 1223-1236
-
-
Cao, W.1
Yacoub, S.2
Shiverick, K.T.3
Namiki, K.4
Sakai, Y.5
Porvasnik, S.6
Urbanek, C.7
Rosser, C.J.8
-
29
-
-
85047692887
-
Expansion of human SCID repopulating cells under hypoxic conditions
-
Danet GH, Pam Y, Luongo JL, Bonnet DA and Simon MC: Expansion of human SCID repopulating cells under hypoxic conditions. J Clin Res 112: 126-135, 2003.
-
(2003)
J Clin Res
, vol.112
, pp. 126-135
-
-
Danet, G.H.1
Pam, Y.2
Luongo, J.L.3
Bonnet, D.A.4
Simon, M.C.5
-
30
-
-
0037478437
-
Hypoxia promotes invasive growth by transcription activation of the met protooncogene
-
Pennacchietti S, Michieli P, Galluzzo M, Mazzone M, Giordano S and Comoglio PM: Hypoxia promotes invasive growth by transcription activation of the met protooncogene. Cell 3: 347-361, 2003.
-
(2003)
Cell
, vol.3
, pp. 347-361
-
-
Pennacchietti, S.1
Michieli, P.2
Galluzzo, M.3
Mazzone, M.4
Giordano, S.5
Comoglio, P.M.6
-
31
-
-
13844250595
-
Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression
-
Gwak GY, Yoon JH, Kim KM, Lee HS, Chung JW and Gores GJ: Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression. J Hepatol 42: 358-364, 2005.
-
(2005)
J Hepatol
, vol.42
, pp. 358-364
-
-
Gwak, G.Y.1
Yoon, J.H.2
Kim, K.M.3
Lee, H.S.4
Chung, J.W.5
Gores, G.J.6
-
32
-
-
34648831748
-
-
Miyashita H, Higa K, Kato N, Kawakita T, Yoshida S, Tsubota K and Shimmura S: Hypoxia enhances the expansion of human limbel epithelial progenitor cells in vitro. Invest Opth Vis Sci 48: 3586-3593, 2007.
-
Miyashita H, Higa K, Kato N, Kawakita T, Yoshida S, Tsubota K and Shimmura S: Hypoxia enhances the expansion of human limbel epithelial progenitor cells in vitro. Invest Opth Vis Sci 48: 3586-3593, 2007.
-
-
-
-
34
-
-
33745155785
-
An abnormal mitochondrial hypoxia inducible factor-1A-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in Fawn hooded rats
-
Bonnet S, D, Michelakis ED, Porter CJ, Andrade-Navarro MA,Thebaud B, Bonnet S, Haromy A, Harry G, Moudgil R, McMurtry S, Weir EK and Archer SL: An abnormal mitochondrial hypoxia inducible factor-1A-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in Fawn hooded rats. Circulation 113: 2630-2641, 2006.
-
(2006)
Circulation
, vol.113
, pp. 2630-2641
-
-
Bonnet, S.D.1
Michelakis, E.D.2
Porter, C.J.3
Andrade-Navarro, M.A.4
Thebaud, B.5
Bonnet, S.6
Haromy, A.7
Harry, G.8
Moudgil, R.9
McMurtry, S.10
Weir, E.K.11
Archer, S.L.12
-
35
-
-
6344257102
-
Dichcloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle apoptosis
-
McMurthry MS, Bonnet S, Wu X, Wu X, Dyck JRB, Haromy A, Hashimoto K and Nichelakis ED: Dichcloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle apoptosis. Circ Res 95: 830, 2004.
-
(2004)
Circ Res
, vol.95
, pp. 830
-
-
McMurthry, M.S.1
Bonnet, S.2
Wu, X.3
Wu, X.4
Dyck, J.R.B.5
Haromy, A.6
Hashimoto, K.7
Nichelakis, E.D.8
-
36
-
-
0032581277
-
Role of HIF-1 in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
Carmeliet P, Dor Y, Herbert J-M, Fukumura D, Brusselmans K, Dewerchin M, Neeman M, Bono F, Abramovitch R, Maxwell P, Roch CJ, Ratcliffe P, Moons L, Jain RK, Collen D and Keshet E: Role of HIF-1 in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394: 485-490, 1998.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.-M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
Roch, C.J.11
Ratcliffe, P.12
Moons, L.13
Jain, R.K.14
Collen, D.15
Keshet, E.16
-
38
-
-
0024379967
-
Acid pH in tumors and its potential for therapeutic exploitation
-
Tannock IF, Rotin D. Acid pH in tumors and its potential for therapeutic exploitation. Can Res 49: 4373-4384, 1989.
-
(1989)
Can Res
, vol.49
, pp. 4373-4384
-
-
Tannock, I.F.1
Rotin, D.2
-
39
-
-
50349100543
-
-
Han X, Xi L, Wang H, Huang X, Ma X, Han Z, Wu P, Ma X, Lu Y, Wang G, Zhou J and Ma Ma: The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells. Biochem Biophys Res Commun 375: 205-209, 2008.
-
(2008)
Zhou J and Ma Ma: The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells. Biochem Biophys Res Commun
, vol.375
, pp. 205-209
-
-
Han, X.1
Xi, L.2
Wang, H.3
Huang, X.4
Ma, X.5
Han, Z.6
Wu, P.7
Ma, X.8
Lu, Y.9
Wang, G.10
-
40
-
-
0242582266
-
2/M entry and transition
-
2/M entry and transition. JBC 278: 44645-44649, 2003.
-
(2003)
JBC
, vol.278
, pp. 44645-44649
-
-
Putney, L.K.1
Barber, D.L.2
-
41
-
-
20244388917
-
Cellular pH regulators: Potentially promising molecular targets for cancer chemotherapy
-
Izumi H, Torigoe T, Ishiguchi H, Uramoto H. Yoshida Y, Tanabe M, Tomoko I, Murakami T, Yoshida T, Nomoto M and Kohna K: Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy. Can Treat Rev 29: 541-549, 2009.
-
(2009)
Can Treat Rev
, vol.29
, pp. 541-549
-
-
Izumi, H.1
Torigoe, T.2
Ishiguchi, H.3
Uramoto, H.4
Yoshida, Y.5
Tanabe, M.6
Tomoko, I.7
Murakami, T.8
Yoshida, T.9
Nomoto, M.10
Kohna, K.11
-
42
-
-
4544246352
-
Alterations of intracellular pH homeostasis in apoptosis: Origins and roles
-
Lagadic-Gossmann D, Huc L and Lecureur V: Alterations of intracellular pH homeostasis in apoptosis: origins and roles. Cell Diff 11: 953-961, 2004.
-
(2004)
Cell Diff
, vol.11
, pp. 953-961
-
-
Lagadic-Gossmann, D.1
Huc, L.2
Lecureur, V.3
-
44
-
-
0032104119
-
+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes
-
+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes. J Clin Invest 101: 2319-2330, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 2319-2330
-
-
Archer, S.L.1
Souil, E.2
Dinh-Xuan, A.T.3
Schremmer, B.4
Mercier, J.C.5
Yaagoubi, A.E.6
Nguyen, L.7
Reeve, H.L.8
Hampl, V.9
-
45
-
-
0033635776
-
Potassium channels: Molecular defects, diseases and therapeutic opportunities
-
Shieh C-C, Coghlan M, Sullivan JP and Gopalakrishnan M: Potassium channels: Molecular defects, diseases and therapeutic opportunities. Pharm Rev 52: 557-594, 2000.
-
(2000)
Pharm Rev
, vol.52
, pp. 557-594
-
-
Shieh, C.-C.1
Coghlan, M.2
Sullivan, J.P.3
Gopalakrishnan, M.4
-
47
-
-
58249094845
-
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
-
Chiche J, Ilc K , Laferriere J, Trottier J, Dayan F, Mazure NM, Brahimi-Horn MC and Pouyssegur J: Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 69: 358-368, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 358-368
-
-
Chiche, J.1
Ilc, K.2
Laferriere, J.3
Trottier, J.4
Dayan, F.5
Mazure, N.M.6
Brahimi-Horn, M.C.7
Pouyssegur, J.8
-
48
-
-
57449115616
-
Tumor metabolism: Cancer cells give and take lactate
-
Semenza GL: Tumor metabolism: cancer cells give and take lactate. J Clin Invest 118: 3835-3837, 2008.
-
(2008)
J Clin Invest
, vol.118
, pp. 3835-3837
-
-
Semenza, G.L.1
-
49
-
-
57449097020
-
-
Sonveaux P,Vegran F, Schroeder T, Wergin MC, Verrax J, Rabbani ZN, De Saedeleer CJ, Kennedy KN, Diepart C, Jordan BF, Kelley MJ, Gallez, Wahl ML, Feron O and Dewhirst MW: Targeting lactate-fueled respiration selectively kills hypoxic cells in mice. J Clin Invest 118: 3930-3942, 2008.
-
Sonveaux P,Vegran F, Schroeder T, Wergin MC, Verrax J, Rabbani ZN, De Saedeleer CJ, Kennedy KN, Diepart C, Jordan BF, Kelley MJ, Gallez, Wahl ML, Feron O and Dewhirst MW: Targeting lactate-fueled respiration selectively kills hypoxic cells in mice. J Clin Invest 118: 3930-3942, 2008.
-
-
-
-
50
-
-
65249095487
-
Prevention of hypoxia by myoglobin expression in human tumor cells promotes differentiation and inhibits metastasis
-
Galluzzo M, Pennacchietti S, Rosano S, Comoglio PM and Michielo P: Prevention of hypoxia by myoglobin expression in human tumor cells promotes differentiation and inhibits metastasis. J Clin Invest 119: 865-875, 2009.
-
(2009)
J Clin Invest
, vol.119
, pp. 865-875
-
-
Galluzzo, M.1
Pennacchietti, S.2
Rosano, S.3
Comoglio, P.M.4
Michielo, P.5
-
51
-
-
60849139085
-
Metabolic enzymes as oncogenes or tumor suppressors
-
Thompson CB: Metabolic enzymes as oncogenes or tumor suppressors. New Eng Med J 360: 813-814, 2009
-
(2009)
New Eng Med J
, vol.360
, pp. 813-814
-
-
Thompson, C.B.1
-
52
-
-
0033746761
-
+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes
-
+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes. FASEB J 14: 2185-2197, 2000.
-
(2000)
FASEB J
, vol.14
, pp. 2185-2197
-
-
Reshkin, S.J.1
Bellizzi, A.2
Caldeira, S.3
Albarani, V.4
Malanchi, I.5
Poignee, M.6
Alunni-Fabroni, M.7
Casavola, V.8
Tommasino, M.9
|