The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells

Biochemical and Biophysical Research Communications

Volumn 375, Issue 2, 2008, Pages 205-209

  Han, Xiaobing ^a,b   Xi, Ling ^a   Wang, Hui ^a   Huang, Xiaoyuan ^a   Ma, Xiangyi ^a   Han, Zhiqiang ^a   Wu, Peng ^a   Ma, XiaoLi ^a   Lu, Yunping ^a   Wang, Gang ^c   Zhou, Jianfeng ^a   Ma, Ding ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Apoptosis; Maxi conductance Ca2+ activated K+ channels (BK channels); NS1619; Ovarian cancer

Indexed keywords

1 (2 HYDROXY 5 TRIFLUOROMETHYLPHENYL) 5 TRIFLUOROMETHYL 2(3H) BENZIMIDAZOLONE; CALCIUM ACTIVATED POTASSIUM CHANNEL; CELL DNA; CYCLIN DEPENDENT KINASE INHIBITOR 1; POTASSIUM CHANNEL; PROTEIN BAX; PROTEIN P21; PROTEIN P53; VOLTAGE GATED POTASSIUM CHANNEL;

APOPTOSIS; ARTICLE; CANCER GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZIMIDAZOLES; CELL LINE, TUMOR; CELL PROLIFERATION; DNA FRAGMENTATION; FEMALE; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; OVARIAN NEOPLASMS; P21-ACTIVATED KINASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 50349100543     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.07.161     Document Type: Article

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