Dichloroacetate increases cell and antibody yields in batch cultures of a hybridoma cell line

Biotechnology and Bioengineering

Volumn 49, Issue 4, 1996, Pages 377-382

  Murray, Kevin ^a   Gull, Keith ^a   Dickson, Alan J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

batch culture; dichloroacetate; hybridoma; metabolism

Indexed keywords

AMINO ACIDS; ANTIBODIES; BATCH CELL CULTURE; BIOCONVERSION; CELLS; ENZYMES; GLUCOSE; GROWTH KINETICS; METABOLISM; METABOLITES;

CATABOLISM; DICHLOROACETATE; GLUTAMINE; GLYCOLYSIS; HYBRIDOMA CELL LINE; LACTATE; NUTRIENTS; PYRUVATE DEHYDROGENASE ACTIVATOR; TRANSAMINATION;

ESTERS;

DICHLOROACETIC ACID; PYRUVATE DEHYDROGENASE;

ANTIBODY PRODUCTION; ARTICLE; CANCER CELL CULTURE; CELL CULTURE; CELL DENSITY; CELL GROWTH; CELL METABOLISM; HYBRIDOMA; KINETICS;

EID: 13344262717     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19960220)49:4<377::AID-BIT3>3.3.CO;2-O     Document Type: Article

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