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Volumn , Issue , 2008, Pages 251-297

Dehydroepiandrosterone and pregnenolone alterations in schizophrenia

Author keywords

anxiety; dehydroepiandrosterone; dehydroepiandrosterone sulfate; metabolism; mode of action; mood and cognitive impairment; Pregnenolone; pregnenolone sulfate; schizophrenia; symptoms

Indexed keywords


EID: 74549211364     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4020-6854-6_14     Document Type: Chapter
Times cited : (14)

References (241)
  • 1
    • 0029992644 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and dehydroepiandrosterone sulfate as neuroactive neurosteroids
    • Baulieu EE, Robel P. Dehydroepiandrosterone and dehydroepiandrosterone sulfate as neuroactive neurosteroids. J Endocrinol 1996;150(Suppl):221-239.
    • (1996) J Endocrinol , vol.150 , Issue.SUPPL. , pp. 221-239
    • Baulieu, E.E.1    Robel, P.2
  • 2
    • 0032498644 scopus 로고    scopus 로고
    • Neuroprotection by dehydroepiandrosterone-sulfate: Role of an NFkappaB-like factor
    • Mao X, Barger SW. Neuroprotection by dehydroepiandrosterone-sulfate: role of an NFkappaB-like factor. Neuroreport 1998;9:759-763.
    • (1998) Neuroreport , vol.9 , pp. 759-763
    • Mao, X.1    Barger, S.W.2
  • 4
    • 0035798383 scopus 로고    scopus 로고
    • Treatment with dehydroepiandrosterone sulfate increases NMDA receptors in hippocampus and cortex
    • Wen S, Dong K, et al. Treatment with dehydroepiandrosterone sulfate increases NMDA receptors in hippocampus and cortex. Eur J Pharmacol 2001;430:373-374.
    • (2001) Eur J Pharmacol , vol.430 , pp. 373-374
    • Wen, S.1    Dong, K.2
  • 5
    • 0036484964 scopus 로고    scopus 로고
    • Uses of DHEA in aging and other disease states
    • Johnson M, Bebb R, Sirrs S. Uses of DHEA in aging and other disease states. Ageing Res Rev 2002;1:29-41.
    • (2002) Ageing Res Rev , vol.1 , pp. 29-41
    • Johnson, M.1    Bebb, R.2    Sirrs, S.3
  • 7
    • 0030630595 scopus 로고    scopus 로고
    • Neurosteroids: Of the nervous system, by the nervous system, for the nervous system
    • Baulieu EE. Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Recent Prog Horm Res 1997;52:1-32.
    • (1997) Recent Prog Horm Res , vol.52 , pp. 1-32
    • Baulieu, E.E.1
  • 8
    • 0032834019 scopus 로고    scopus 로고
    • Gonadal steroids in the treatment of mood disorders
    • Epperson CN, Wisner KL, Yamamoto B. Gonadal steroids in the treatment of mood disorders. Psychosom Med 1999;61:676-697.
    • (1999) Psychosom Med , vol.61 , pp. 676-697
    • Epperson, C.N.1    Wisner, K.L.2    Yamamoto, B.3
  • 10
    • 33847776196 scopus 로고    scopus 로고
    • Neuroactive steroids in depression and anxiety disorders: Clinical studies
    • Eser D, Schule C, Baghai TC, et al. Neuroactive steroids in depression and anxiety disorders: clinical studies. Neuroendocrinology 2006;84:244-254.
    • (2006) Neuroendocrinology , vol.84 , pp. 244-254
    • Eser, D.1    Schule, C.2    Baghai, T.C.3
  • 11
    • 0033953033 scopus 로고    scopus 로고
    • Neurosteroids: Biosynthesis and function of these novel neuromodulators
    • Compagnone NA, Mellon SH. Neurosteroids: biosynthesis and function of these novel neuromodulators. Front Neuroendocrinol 2000;21:1-56.
    • (2000) Front Neuroendocrinol , vol.21 , pp. 1-56
    • Compagnone, N.A.1    Mellon, S.H.2
  • 12
    • 0035206892 scopus 로고    scopus 로고
    • Neurosteroid metabolism in the human brain
    • Stoffel-Wagner B. Neurosteroid metabolism in the human brain. Eur J Endocrinol 2001;145:669-679.
    • (2001) Eur J Endocrinol , vol.145 , pp. 669-679
    • Stoffel-Wagner, B.1
  • 13
    • 1342330548 scopus 로고    scopus 로고
    • Neurosteroid biosynthesis in the human brain and its clinical implications
    • Stoffel-Wagner B. Neurosteroid biosynthesis in the human brain and its clinical implications. Ann NY Acad Sci 2003;1007:64-78.
    • (2003) Ann NY Acad Sci , vol.1007 , pp. 64-78
    • Stoffel-Wagner, B.1
  • 14
    • 28044466662 scopus 로고    scopus 로고
    • Is dehydroepiandrosterone a hormone?
    • Labrie F, Luu-The V, Belanger A, et al. Is dehydroepiandrosterone a hormone? J Endocrinol 2005;187:169-196.
    • (2005) J Endocrinol , vol.187 , pp. 169-196
    • Labrie, F.1    Luu-The, V.2    Belanger, A.3
  • 15
    • 0025930826 scopus 로고
    • Neurosteroids: Biosynthesis, metabolism and function of pregnenolone and dehydroepiandrosterone in the brain
    • Le Goascogne C, Jo DH, Corpéchot C. Neurosteroids: biosynthesis, metabolism and function of pregnenolone and dehydroepiandrosterone in the brain. J Steroid Biochem 1991;40:71-81.
    • (1991) J Steroid Biochem , vol.40 , pp. 71-81
    • Le Goascogne, C.1    Jo, D.H.2    Corpéchot, C.3
  • 16
    • 0037293399 scopus 로고    scopus 로고
    • Neuroactive steroids: Mechanisms of action and neuropsychopharmacological properties
    • Rupprecht R. Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties. Psychoneuroendocrinology 2003;28:139-168.
    • (2003) Psychoneuroendocrinology , vol.28 , pp. 139-168
    • Rupprecht, R.1
  • 17
    • 0032448780 scopus 로고    scopus 로고
    • Neurosteroids: A novel function of the brain
    • Baulieu EE. Neurosteroids: a novel function of the brain. Psychoneuroendocrinology 1998;23:963-987.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 963-987
    • Baulieu, E.E.1
  • 18
    • 0032910967 scopus 로고    scopus 로고
    • Dehydroepiandrosterone: Biosynthesis and metabolism in the brain
    • Zwain IH, Yen SS. Dehydroepiandrosterone: biosynthesis and metabolism in the brain. Endocrinology 1999;140:880-887.
    • (1999) Endocrinology , vol.140 , pp. 880-887
    • Zwain, I.H.1    Yen, S.S.2
  • 19
    • 0029549968 scopus 로고
    • Human dehydroepiandrosterone sulfotransferase. Purification, molecular cloning, and characterization
    • Falany CN, Comer KA, Dooley TP, Glatt H. Human dehydroepiandrosterone sulfotransferase. Purification, molecular cloning, and characterization. Ann NY Acad Sci 1995;774:59-72.
    • (1995) Ann NY Acad Sci , vol.774 , pp. 59-72
    • Falany, C.N.1    Comer, K.A.2    Dooley, T.P.3    Glatt, H.4
  • 21
    • 0028309503 scopus 로고
    • Dehydroepiandrosterone (DHEA) - The multifunctional steroid. II. Effects on the CNS, cell proliferation, metabolic and vascular, clinical and other effects. Mechanism of action?
    • Regelson W, Kalimi M. Dehydroepiandrosterone (DHEA) - the multifunctional steroid. II. Effects on the CNS, cell proliferation, metabolic and vascular, clinical and other effects. Mechanism of action? Ann NY Acad Sci 1994;719:564-575.
    • (1994) Ann NY Acad Sci , vol.719 , pp. 564-575
    • Regelson, W.1    Kalimi, M.2
  • 22
    • 0033055713 scopus 로고    scopus 로고
    • Effect of oral androstenedione on serum testosterone and adaptations to resistance training in young men: A randomized controlled trial
    • King DS, Sharp RL, Vukovich MD, et al. Effect of oral androstenedione on serum testosterone and adaptations to resistance training in young men: a randomized controlled trial. JAMA 1999;281:2020-2028.
    • (1999) JAMA , vol.281 , pp. 2020-2028
    • King, D.S.1    Sharp, R.L.2    Vukovich, M.D.3
  • 23
    • 0034645448 scopus 로고    scopus 로고
    • The Andro Project: Physiological and hormonal influences of androstenedione supplementation in men 35 to 65 years old participating in a high-intensity resistance training program
    • Broeder CE, Quindry J, Brittingham K, et al. The Andro Project: physiological and hormonal influences of androstenedione supplementation in men 35 to 65 years old participating in a high-intensity resistance training program. Arch Intern Med 2000;160:3093-3104.
    • (2000) Arch Intern Med , vol.160 , pp. 3093-3104
    • Broeder, C.E.1    Quindry, J.2    Brittingham, K.3
  • 24
    • 0021129014 scopus 로고
    • Dehydroepiandrosterone sulfate: Kinetics of metabolism in normal young men and women
    • Bird CE, Masters V, Clark AF. Dehydroepiandrosterone sulfate: kinetics of metabolism in normal young men and women. Clin Invest Med 1984;7:119-122.
    • (1984) Clin Invest Med , vol.7 , pp. 119-122
    • Bird, C.E.1    Masters, V.2    Clark, A.F.3
  • 25
    • 0029857982 scopus 로고    scopus 로고
    • Dehydroepiandrosterone metabolism
    • Longcope C. Dehydroepiandrosterone metabolism. J Endocrinol 1996 (Suppl); 150:125-127.
    • (1996) J Endocrinol , vol.150 , Issue.SUPPL. , pp. 125-127
    • Longcope, C.1
  • 27
    • 0030821426 scopus 로고    scopus 로고
    • The neuropsychopharmacological potential of neuroactive steroids
    • Rupprecht R. The neuropsychopharmacological potential of neuroactive steroids. J Psychiatr Res 1997;31:297-314.
    • (1997) J Psychiatr Res , vol.31 , pp. 297-314
    • Rupprecht, R.1
  • 29
    • 0032076761 scopus 로고    scopus 로고
    • DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: Its role during aging
    • Labrie F, Belanger A, Van LT, et al. DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging. Steroids 1998;63:322-328.
    • (1998) Steroids , vol.63 , pp. 322-328
    • Labrie, F.1    Belanger, A.2    Van, L.T.3
  • 30
    • 0032871575 scopus 로고    scopus 로고
    • Effect of dehydroepiandrosterone and its sulfate and fatty acid ester derivatives on rat brain membranes
    • Morissette M, Dicko A, Pezolet M, et al. Effect of dehydroepiandrosterone and its sulfate and fatty acid ester derivatives on rat brain membranes. Steroids 1999;64:796-803.
    • (1999) Steroids , vol.64 , pp. 796-803
    • Morissette, M.1    Dicko, A.2    Pezolet, M.3
  • 31
    • 0033113514 scopus 로고    scopus 로고
    • Role of a novel KCa opener in regulating K channels of hypoxic human pulmonary vascular cells
    • Peng W, Hoidal JR, Farrukh IS. Role of a novel KCa opener in regulating K channels of hypoxic human pulmonary vascular cells. Am J Respir Cell Mol Biol 1999;20:737-745.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 737-745
    • Peng, W.1    Hoidal, J.R.2    Farrukh, I.S.3
  • 32
    • 0028904867 scopus 로고
    • On the mechanism of interaction of steroids with human glucose 6-phosphate dehydrogenase
    • Gordon G, Mackow MC, Levy HR. On the mechanism of interaction of steroids with human glucose 6-phosphate dehydrogenase. Arch Biochem Biophys 1995;318:25-29.
    • (1995) Arch Biochem Biophys , vol.318 , pp. 25-29
    • Gordon, G.1    Mackow, M.C.2    Levy, H.R.3
  • 33
    • 11144298641 scopus 로고    scopus 로고
    • Adrenal androgens in human physiology
    • Bruce RC editor in chief; William ER, Bruce RC guest editors
    • Widstrom RL, Dillon JS. Adrenal androgens in human physiology. Bruce RC (editor in chief); William ER, Bruce RC (guest editors) Semin Reprod Med 2004;22:289-298.
    • (2004) Semin Reprod Med , vol.22 , pp. 289-298
    • Widstrom, R.L.1    Dillon, J.S.2
  • 34
    • 0026509649 scopus 로고
    • Neurosteroids: Endogenous bimodal modulators of the GABA-A receptor. Mechanism of action and physiological significance
    • Majewska MD. Neurosteroids: endogenous bimodal modulators of the GABA-A receptor. Mechanism of action and physiological significance. Prog Neurobiol 1992;38:379-395.
    • (1992) Prog Neurobiol , vol.38 , pp. 379-395
    • Majewska, M.D.1
  • 36
    • 0025091447 scopus 로고
    • The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor
    • Majewska MD, Demigören S, Spivak CE, London ED. The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor. Brain Res 1990;526:143-146.
    • (1990) Brain Res , vol.526 , pp. 143-146
    • Majewska, M.D.1    Demigören, S.2    Spivak, C.E.3    London, E.D.4
  • 37
    • 0025941858 scopus 로고
    • Receptor binding and electrophysiological effects of dehydroepiandrosterone sulfate, an antagonist of the GABAA receptor
    • Demirgoren S, Majewska MD, Spivak CE, London ED. Receptor binding and electrophysiological effects of dehydroepiandrosterone sulfate, an antagonist of the GABAA receptor. Neuroscience 1991;45:127-135.
    • (1991) Neuroscience , vol.45 , pp. 127-135
    • Demirgoren, S.1    Majewska, M.D.2    Spivak, C.E.3    London, E.D.4
  • 38
    • 0029912702 scopus 로고    scopus 로고
    • Potentiation by dehydroepiandrosterone of the neuronal response to N-methyl-D-aspartate in the CA3 region of the rat dorsal hippocampus: An effect mediated via sigma receptors
    • Debonnel G, Bergeron R, De Montigny C. Potentiation by dehydroepiandrosterone of the neuronal response to N-methyl-D-aspartate in the CA3 region of the rat dorsal hippocampus: an effect mediated via sigma receptors. J Endocrinol 1996 (Suppl) 150:33-42.
    • (1996) J Endocrinol , vol.150 , Issue.SUPPL. , pp. 33-42
    • Debonnel, G.1    Bergeron, R.2    De Montigny, C.3
  • 39
    • 0034648042 scopus 로고    scopus 로고
    • Neurosteroid modulation of embryonic neuronal survival in vitro following anoxia
    • Marx CE, Jarskog LF, Lauder JM, et al. Neurosteroid modulation of embryonic neuronal survival in vitro following anoxia. Brain Res 2000;871:104-112.
    • (2000) Brain Res , vol.871 , pp. 104-112
    • Marx, C.E.1    Jarskog, L.F.2    Lauder, J.M.3
  • 40
    • 0026579057 scopus 로고
    • Neuroactive steroids
    • Paul SM, Purdy RH. Neuroactive steroids. FASEB J 1992;6:2311-2322.
    • (1992) FASEB J , vol.6 , pp. 2311-2322
    • Paul, S.M.1    Purdy, R.H.2
  • 42
    • 0034610292 scopus 로고    scopus 로고
    • Gamma-Aminobutyric acid, acting through gamma-aminobutyric acid type A receptors, inhibits the biosynthesis of neurosteroids in the frog hypothalamus
    • Do-Rego JL, Mensah-Nyagan GA, Beaujean D, Vaudry D, et al. gamma-Aminobutyric acid, acting through gamma-aminobutyric acid type A receptors, inhibits the biosynthesis of neurosteroids in the frog hypothalamus. Proc Natl Acad Sci USA 2000;97:13925-13930.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13925-13930
    • Do-Rego, J.L.1    Mensah-Nyagan, G.A.2    Beaujean, D.3    Vaudry, D.4
  • 43
    • 0037212021 scopus 로고    scopus 로고
    • Clozapine decreases rat brain dehydroepiandrosterone and dehydroepiandrosterone sulfate levels
    • Nechmad A, Maayan R, Ramadan E, et al. Clozapine decreases rat brain dehydroepiandrosterone and dehydroepiandrosterone sulfate levels. Eur Neuropsychopharmacol 2003;13:29-31.
    • (2003) Eur Neuropsychopharmacol , vol.13 , pp. 29-31
    • Nechmad, A.1    Maayan, R.2    Ramadan, E.3
  • 44
    • 0028889119 scopus 로고
    • Pregnenolone sulfate potentiation of NMDA-mediated increases in intracellular calcium in cultured chick cortical neurons
    • Fahey JM, Lindquist DG, Pritchard GA, Miller LG. Pregnenolone sulfate potentiation of NMDA-mediated increases in intracellular calcium in cultured chick cortical neurons. Brain Res 1995;669:183-188.
    • (1995) Brain Res , vol.669 , pp. 183-188
    • Fahey, J.M.1    Lindquist, D.G.2    Pritchard, G.A.3    Miller, L.G.4
  • 46
    • 23444443864 scopus 로고    scopus 로고
    • Neurosteroid pregnenolone sulfate inhibits stimulus-evoked EPSC via presynaptic inhibition of protein kinase A in rat prelimbic cortical neurons
    • Sun JL, Dong YL, Fu YM, et al. Neurosteroid pregnenolone sulfate inhibits stimulus-evoked EPSC via presynaptic inhibition of protein kinase A in rat prelimbic cortical neurons. Neuropharmacology 2005;49:389-399.
    • (2005) Neuropharmacology , vol.49 , pp. 389-399
    • Sun, J.L.1    Dong, Y.L.2    Fu, Y.M.3
  • 47
    • 29744463364 scopus 로고    scopus 로고
    • Subtype-dependence of N-methyl-Daspartate receptor modulation by pregnenolone sulfate
    • Horak M, Vlcek K, Chodounska H, Vyklicky L, Jr. Subtype-dependence of N-methyl-Daspartate receptor modulation by pregnenolone sulfate. Neuroscience 2006;137:93-102.
    • (2006) Neuroscience , vol.137 , pp. 93-102
    • Horak, M.1    Vlcek, K.2    Chodounska, H.3    Vyklicky Jr., L.4
  • 48
    • 33750077567 scopus 로고    scopus 로고
    • Neurosteroid pregnenolone sulfate enhances glutamatergic synaptic transmission by facilitating presynaptic calcium currents at the calyx of Held of immature rats
    • Hige T, Fujiyoshi Y, Takahashi T. Neurosteroid pregnenolone sulfate enhances glutamatergic synaptic transmission by facilitating presynaptic calcium currents at the calyx of Held of immature rats. Eur J Neurosci 2006;24:1955-1966.
    • (2006) Eur J Neurosci , vol.24 , pp. 1955-1966
    • Hige, T.1    Fujiyoshi, Y.2    Takahashi, T.3
  • 49
    • 0030010448 scopus 로고    scopus 로고
    • Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: Effects mediated via sigma receptors
    • Bergeron R, De Montigny C, et al. Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors. J Neurosci 1996;16:1193-1202.
    • (1996) J Neurosci , vol.16 , pp. 1193-1202
    • Bergeron, R.1    De Montigny, C.2
  • 50
    • 22044458190 scopus 로고    scopus 로고
    • Pregnenolone sulfate acts through a G-protein-coupled sigma1-like receptor to enhance short term facilitation in adult hippocampal neurons
    • Schiess AR, Partridge LD. Pregnenolone sulfate acts through a G-protein-coupled sigma1-like receptor to enhance short term facilitation in adult hippocampal neurons. Eur J Pharmacol 2005;518:22-29.
    • (2005) Eur J Pharmacol , vol.518 , pp. 22-29
    • Schiess, A.R.1    Partridge, L.D.2
  • 51
    • 0032516942 scopus 로고    scopus 로고
    • 1) receptor mediated antidepressant-like effects of neurosteroids in the Porsolt forced swim test
    • 1) receptor mediated antidepressant-like effects of neurosteroids in the Porsolt forced swim test. Neuroreport 1998;9:3069-3073.
    • (1998) Neuroreport , vol.9 , pp. 3069-3073
    • Reddy, D.S.1    Kaur, G.2    Kulkarni, S.K.3
  • 52
    • 0028213506 scopus 로고
    • Dehydroepiandrosterone is an anxiolytic in mice on the plus maze
    • Melchior CL, Ritzmann RF. Dehydroepiandrosterone is an anxiolytic in mice on the plus maze. Pharmacol Biochem Behav 1994;47:437-444.
    • (1994) Pharmacol Biochem Behav , vol.47 , pp. 437-444
    • Melchior, C.L.1    Ritzmann, R.F.2
  • 53
    • 21744447595 scopus 로고    scopus 로고
    • Neurosteroids: Endogenous regulators of the GABA (A) receptor
    • Belelli D, Lambert JJ. Neurosteroids: endogenous regulators of the GABA (A) receptor. Nat Rev Neurosci 2005;6:565-575.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 565-575
    • Belelli, D.1    Lambert, J.J.2
  • 54
    • 0029552745 scopus 로고
    • Neuractive steroid modulators of the stress response
    • Chrousos GP, McCarty R, Pacák K, Cizza G, Sternberg E, Gold PW, Kvetnansky R eds, New York: The New York Academy of Sciences
    • Morrow AL, Devaud LL, Purdy RH, Paul SM. Neuractive steroid modulators of the stress response. In: Chrousos GP, McCarty R, Pacák K, Cizza G, Sternberg E, Gold PW, Kvetnansky R (eds). Stress: basic mechanisms and clinical implications. New York: The New York Academy of Sciences, 1995, 257-272.
    • (1995) Stress: Basic Mechanisms and Clinical Implications , pp. 257-272
    • Morrow, A.L.1    Devaud, L.L.2    Purdy, R.H.3    Paul, S.M.4
  • 55
    • 0035956852 scopus 로고    scopus 로고
    • Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation
    • Dong E, Matsumoto K, Uzunova V, et al. Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation. Proc Natl Acad Sci USA 2001;98:2849-2854.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2849-2854
    • Dong, E.1    Matsumoto, K.2    Uzunova, V.3
  • 56
    • 0035413129 scopus 로고    scopus 로고
    • Stress hormone-related psychopathology: Pathophysiological and treatment implications
    • Wolkowitz OM, Epel ES, et al. Stress hormone-related psychopathology: pathophysiological and treatment implications. World J Biol Psychiatry 2001;2:115-143.
    • (2001) World J Biol Psychiatry , vol.2 , pp. 115-143
    • Wolkowitz, O.M.1    Epel, E.S.2
  • 57
    • 0033980873 scopus 로고    scopus 로고
    • Anti-stress effects of dehydroepiandrosterone: Protection of rats against repeated immobilization stress-induced weight loss, glucocorticoid receptor production, and lipid peroxidation
    • Hu Y, Cardounel A, et al. Anti-stress effects of dehydroepiandrosterone: protection of rats against repeated immobilization stress-induced weight loss, glucocorticoid receptor production, and lipid peroxidation. Biochem Pharmacol 2000;59:753-762.
    • (2000) Biochem Pharmacol , vol.59 , pp. 753-762
    • Hu, Y.1    Cardounel, A.2
  • 58
    • 0036283442 scopus 로고    scopus 로고
    • Study of the stress response: Role of anxiety, cortisol and DHEAs
    • Boudarene M, Legros JJ, et al. Study of the stress response: role of anxiety, cortisol and DHEAs. Encephale 2002;28:139-146.
    • (2002) Encephale , vol.28 , pp. 139-146
    • Boudarene, M.1    Legros, J.J.2
  • 59
    • 1842558358 scopus 로고    scopus 로고
    • The neuroendocrinology of posttraumatic stress disorder: New directions
    • 665-667
    • Rasmusson AM, Vythilingam M, Morgan CA 3rd. The neuroendocrinology of posttraumatic stress disorder: new directions. CNS Spectr 2003;8:651-566, 665-667.
    • (2003) CNS Spectr , vol.8 , pp. 651-566
    • Rasmusson, A.M.1    Vythilingam, M.2    Morgan III, C.A.3
  • 60
    • 3242791689 scopus 로고    scopus 로고
    • An increased capacity for adrenal DHEA release is associated with decreased avoidance and negative mood symptoms in women with PTSD
    • Rasmusson AM, Vasek J, Lipschitz DS, et al. An increased capacity for adrenal DHEA release is associated with decreased avoidance and negative mood symptoms in women with PTSD. Neuropsychopharmacology 2004;29:1546-1557.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1546-1557
    • Rasmusson, A.M.1    Vasek, J.2    Lipschitz, D.S.3
  • 61
    • 33747190652 scopus 로고    scopus 로고
    • Prolonged decrease in stress reactivity caused by dehydroepiandrosterone sulfate
    • Obut TA, Ovsyukova MV, Cherkasova OP. Prolonged decrease in stress reactivity caused by dehydroepiandrosterone sulfate. Bull Exp Biol Med 2006;141:571-573.
    • (2006) Bull Exp Biol Med , vol.141 , pp. 571-573
    • Obut, T.A.1    Ovsyukova, M.V.2    Cherkasova, O.P.3
  • 62
    • 0028230009 scopus 로고
    • Anti-glucocorticoid effects of dehydroepiandrosterone (DHEA)
    • Kalimi M, Shafagoj Y, Loria R. Anti-glucocorticoid effects of dehydroepiandrosterone (DHEA). Mol Cell Biochem 1994;131:99-104.
    • (1994) Mol Cell Biochem , vol.131 , pp. 99-104
    • Kalimi, M.1    Shafagoj, Y.2    Loria, R.3
  • 63
    • 0033103126 scopus 로고    scopus 로고
    • Dehydroepiandrosterone antagonizes the neurotoxic effects of corticosterone and translocation of stress-activated protein kinase 3 in hippocampal primary cultures
    • Kimonides VG, Spillantini MG, et al. Dehydroepiandrosterone antagonizes the neurotoxic effects of corticosterone and translocation of stress-activated protein kinase 3 in hippocampal primary cultures. Neuroscience 1999;89:429-436.
    • (1999) Neuroscience , vol.89 , pp. 429-436
    • Kimonides, V.G.1    Spillantini, M.G.2
  • 64
    • 0036460078 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosteroneinduced suppression
    • Karishma KK, Herbert J. Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosteroneinduced suppression. Eur J Neurosci 2002;16:445-453.
    • (2002) Eur J Neurosci , vol.16 , pp. 445-453
    • Karishma, K.K.1    Herbert, J.2
  • 66
    • 0021799792 scopus 로고
    • Dissociation of adrenal androgen and cortisol levels in acute stress
    • Parker L, Eugene J, Farber D, et al. Dissociation of adrenal androgen and cortisol levels in acute stress. Horm Metab Res 1985;17:209-212.
    • (1985) Horm Metab Res , vol.17 , pp. 209-212
    • Parker, L.1    Eugene, J.2    Farber, D.3
  • 67
    • 0030921207 scopus 로고    scopus 로고
    • Relationship of dehydroepiandrosterone and cortisol in disease
    • Hechter O, Grossman A, Chatterton RT. Relationship of dehydroepiandrosterone and cortisol in disease. Med Hypotheses 1997;49:85-91.
    • (1997) Med Hypotheses , vol.49 , pp. 85-91
    • Hechter, O.1    Grossman, A.2    Chatterton, R.T.3
  • 68
    • 0031958870 scopus 로고    scopus 로고
    • Adrenal steroid secretion and major depression in 8-to 16-year-olds. III. Influence of cortisol/DHEA ratio at presentation on subsequent rates of disappointing life events and persistent major depression
    • Goodyer IM, Herbert J, Altham PM. Adrenal steroid secretion and major depression in 8-to 16-year-olds. III. Influence of cortisol/DHEA ratio at presentation on subsequent rates of disappointing life events and persistent major depression. Psychol Med 1998;28:265-273.
    • (1998) Psychol Med , vol.28 , pp. 265-273
    • Goodyer, I.M.1    Herbert, J.2    Altham, P.M.3
  • 69
    • 0034857092 scopus 로고    scopus 로고
    • Possible role of cortisol and dehydroepiandrosterone in human development and psychopathology
    • Goodyer IM, Park RJ, Netherton CM, Herbert J. Possible role of cortisol and dehydroepiandrosterone in human development and psychopathology. Br J Psychiatry 2001;179:243-249.
    • (2001) Br J Psychiatry , vol.179 , pp. 243-249
    • Goodyer, I.M.1    Park, R.J.2    Netherton, C.M.3    Herbert, J.4
  • 70
    • 12244307847 scopus 로고    scopus 로고
    • Influence of DHEA administration on 24-hour cortisol concentrations
    • Kroboth PD, Amico JA, Stone RA, et al. Influence of DHEA administration on 24-hour cortisol concentrations. J Clin Psychopharmacol 2003;23:96-99.
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 96-99
    • Kroboth, P.D.1    Amico, J.A.2    Stone, R.A.3
  • 72
    • 33751010437 scopus 로고    scopus 로고
    • Effects of neurosteroids on glucocorticoid receptor-mediated gene transcription in LMCAT cells - A possible interaction with psychotropic drugs
    • Basta-Kaim A, Budziszewska B, Jaworska-Feil L, et al. Effects of neurosteroids on glucocorticoid receptor-mediated gene transcription in LMCAT cells - A possible interaction with psychotropic drugs. Eur Neuropsychopharmacol 2007;17:37-45.
    • (2007) Eur Neuropsychopharmacol , vol.17 , pp. 37-45
    • Basta-Kaim, A.1    Budziszewska, B.2    Jaworska-Feil, L.3
  • 73
    • 0023126569 scopus 로고
    • Effects of dehydroepiandrosterone and its sulfate on brain tissue in culture and on memory in mice
    • Roberts E, Bologa L, Flood JF, Smith GE. Effects of dehydroepiandrosterone and its sulfate on brain tissue in culture and on memory in mice. Brain Res 1987;406:357-362.
    • (1987) Brain Res , vol.406 , pp. 357-362
    • Roberts, E.1    Bologa, L.2    Flood, J.F.3    Smith, G.E.4
  • 74
    • 0023188288 scopus 로고
    • Dehydroepiandrosterone and its sulfated derivative reduce neuronal death and enhance astrocytic differentiation in brain cell cultures
    • Bologa L, Sharma J, et al. Dehydroepiandrosterone and its sulfated derivative reduce neuronal death and enhance astrocytic differentiation in brain cell cultures. J Neurosci Res 1987;17:225-234.
    • (1987) J Neurosci Res , vol.17 , pp. 225-234
    • Bologa, L.1    Sharma, J.2
  • 75
    • 0030036766 scopus 로고    scopus 로고
    • Development and regeneration of the nervous system: A role for neurosteroids
    • Schumacher M, Robel P, Baulieu EE. Development and regeneration of the nervous system: a role for neurosteroids. Dev Neurosci 1996;18:6-21.
    • (1996) Dev Neurosci , vol.18 , pp. 6-21
    • Schumacher, M.1    Robel, P.2    Baulieu, E.E.3
  • 77
    • 0032516063 scopus 로고    scopus 로고
    • Dehydroepiandrosterone: A potential signalling molecule for neocortical organization during development
    • Compagnone NA, Mellon SH. Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development. Proc Natl Acad Sci USA 1998;95:4678-4683.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4678-4683
    • Compagnone, N.A.1    Mellon, S.H.2
  • 78
    • 0035023544 scopus 로고    scopus 로고
    • Pregnenolone protects mouse hippocampal (HT-22) cells against glutamate and amyloid beta protein toxicity
    • Gursoy E, Cardounel A, et al. Pregnenolone protects mouse hippocampal (HT-22) cells against glutamate and amyloid beta protein toxicity. Neurochem Res 2001;26:15-21.
    • (2001) Neurochem Res , vol.26 , pp. 15-21
    • Gursoy, E.1    Cardounel, A.2
  • 79
    • 20444446379 scopus 로고    scopus 로고
    • Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons
    • Shirakawa H, Katsuki H, Kume T, et al. Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons. Eur J Neurosci 2005;21:2329-2335.
    • (2005) Eur J Neurosci , vol.21 , pp. 2329-2335
    • Shirakawa, H.1    Katsuki, H.2    Kume, T.3
  • 80
    • 0042510232 scopus 로고    scopus 로고
    • Neuroprotection by the steroids pregnenolone and dehydroepiandrosterone is mediated by the enzyme aromatase
    • Veiga S, Garcia-Segura LM, et al. Neuroprotection by the steroids pregnenolone and dehydroepiandrosterone is mediated by the enzyme aromatase. J Neurobiol 2003;56:398-406.
    • (2003) J Neurobiol , vol.56 , pp. 398-406
    • Veiga, S.1    Garcia-Segura, L.M.2
  • 81
    • 34447570373 scopus 로고    scopus 로고
    • Neurosteroids as endogenous inhibitors of neuronal cell apoptosis in aging
    • Charalampopoulos I, Alexaki VI, Tsatsanis C, et al. Neurosteroids as endogenous inhibitors of neuronal cell apoptosis in aging. Ann NY Acad Sci 2006;1088:139-152.
    • (2006) Ann NY Acad Sci , vol.1088 , pp. 139-152
    • Charalampopoulos, I.1    Alexaki, V.I.2    Tsatsanis, C.3
  • 82
    • 33748743545 scopus 로고    scopus 로고
    • Adrenarche and the evolution of human life history
    • Campbell B. Adrenarche and the evolution of human life history. Am J Hum Biol 2006;18:569-589.
    • (2006) Am J Hum Biol , vol.18 , pp. 569-589
    • Campbell, B.1
  • 83
    • 0026542895 scopus 로고
    • Memory-enhancing effects in male mice of pregnenolone and of steroids metabolically derived from it
    • Flood JF, Morley JE, Roberts E. Memory-enhancing effects in male mice of pregnenolone and of steroids metabolically derived from it. Proc Natl Acad Sci USA 1992;89:1567-1571.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1567-1571
    • Flood, J.F.1    Morley, J.E.2    Roberts, E.3
  • 84
    • 0028853687 scopus 로고
    • Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures
    • Flood J., et al. Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures. Proc Nat Acad Sci USA 1995;92:10806-108010.
    • (1995) Proc Nat Acad Sci USA , vol.92 , pp. 10806-108010
    • Flood, J.1
  • 85
    • 0029074788 scopus 로고
    • Biosynthesis and assay of neurosteroids in rats and mice: Functional correlates
    • Robel P, Young J, Corpechot C, et al. Biosynthesis and assay of neurosteroids in rats and mice: functional correlates. J Steroid Biochem Mol Biol 1995;53:355-360.
    • (1995) J Steroid Biochem Mol Biol , vol.53 , pp. 355-360
    • Robel, P.1    Young, J.2    Corpechot, C.3
  • 86
    • 0027394538 scopus 로고
    • Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat
    • Mayo W, Dellu F, Robel P, et al. Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat. Brain Res 1993;607:324-328.
    • (1993) Brain Res , vol.607 , pp. 324-328
    • Mayo, W.1    Dellu, F.2    Robel, P.3
  • 87
    • 0029146316 scopus 로고
    • The effects of pregnenolone sulfate and ethylestrenol on retention of a passive avoidance task
    • Isaacson RL, Varner JA, Baars J-M, De Wied D. The effects of pregnenolone sulfate and ethylestrenol on retention of a passive avoidance task. Brain Res 1995;689:79-84.
    • (1995) Brain Res , vol.689 , pp. 79-84
    • Isaacson, R.L.1    Varner, J.A.2    Baars, J.-M.3    De Wied, D.4
  • 88
    • 0028032491 scopus 로고
    • The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task
    • Mathis C, Paul SM, Crawley JN. The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task. Psychopharmacology (Berl) 1994;116:201-206.
    • (1994) Psychopharmacology (Berl) , vol.116 , pp. 201-206
    • Mathis, C.1    Paul, S.M.2    Crawley, J.N.3
  • 89
    • 0029145499 scopus 로고
    • Pregnenolone sulfate antagonizes dizocilpine amnesia: Role for allopregnanolone
    • Cheney DL, Uzunov D, Guidotti A. Pregnenolone sulfate antagonizes dizocilpine amnesia: role for allopregnanolone. Neuroreport 1995;6:1697-1700.
    • (1995) Neuroreport , vol.6 , pp. 1697-1700
    • Cheney, D.L.1    Uzunov, D.2    Guidotti, A.3
  • 90
    • 0029670384 scopus 로고    scopus 로고
    • Neurosteroids block the memory-impairing effects of ethanol in mice
    • Melchior CL, Ritzmann RF. Neurosteroids block the memory-impairing effects of ethanol in mice. Pharmacol Biochem Behav 1996;53:51-56.
    • (1996) Pharmacol Biochem Behav , vol.53 , pp. 51-56
    • Melchior, C.L.1    Ritzmann, R.F.2
  • 91
    • 0027155274 scopus 로고
    • Pregnenolone sulfate potentiation of N-methyl-d-aspartate receptor channels in hippocampal neurons
    • Bowlby MR. Pregnenolone sulfate potentiation of N-methyl-d-aspartate receptor channels in hippocampal neurons. Mol Pharmacol 1993;43:813-819.
    • (1993) Mol Pharmacol , vol.43 , pp. 813-819
    • Bowlby, M.R.1
  • 92
    • 0030445549 scopus 로고    scopus 로고
    • The neurosteroid pregnenolone sulfate blocks deficits induced by a competitive NMDA antagonist in active avoidance and lever-press learning tasks in mice
    • Mathis C, Vogel E, Cagniard B, et al. The neurosteroid pregnenolone sulfate blocks deficits induced by a competitive NMDA antagonist in active avoidance and lever-press learning tasks in mice. Neuropharmacology 1996;35:1057-1064.
    • (1996) Neuropharmacology , vol.35 , pp. 1057-1064
    • Mathis, C.1    Vogel, E.2    Cagniard, B.3
  • 93
    • 0035088433 scopus 로고    scopus 로고
    • Memory-enhancing effects of DHEAS in aged mice on a win-shift water escape task
    • Markowski M, Ungeheuer M, Bitran D, Locurto C. Memory-enhancing effects of DHEAS in aged mice on a win-shift water escape task. Physiol Behav 2001;72:521-525.
    • (2001) Physiol Behav , vol.72 , pp. 521-525
    • Markowski, M.1    Ungeheuer, M.2    Bitran, D.3    Locurto, C.4
  • 94
    • 0035666911 scopus 로고    scopus 로고
    • Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging
    • Vallee M, Mayo W, Le Moal M. Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging. Brain Res Brain Res Rev 2001;37:301-312.
    • (2001) Brain Res Brain Res Rev , vol.37 , pp. 301-312
    • Vallee, M.1    Mayo, W.2    Le Moal, M.3
  • 95
    • 0030590485 scopus 로고    scopus 로고
    • Enhancement of hippocampal acetylcholine release by the neurosteroid dehydroepiandrosterone sulfate: An in vivo microdialysis study
    • Rhodes ME, Li PK, et al. Enhancement of hippocampal acetylcholine release by the neurosteroid dehydroepiandrosterone sulfate: an in vivo microdialysis study. Brain Res 1996;733:284-286.
    • (1996) Brain Res , vol.733 , pp. 284-286
    • Rhodes, M.E.1    Li, P.K.2
  • 96
    • 0030671365 scopus 로고    scopus 로고
    • Enhanced plasma DHEAS, brain acetylcholine and memory mediated by steroid sulfatase inhibition
    • Rhodes ME, Li PK, et al. Enhanced plasma DHEAS, brain acetylcholine and memory mediated by steroid sulfatase inhibition. Brain Res 1997;773:28-32.
    • (1997) Brain Res , vol.773 , pp. 28-32
    • Rhodes, M.E.1    Li, P.K.2
  • 97
    • 0342981444 scopus 로고    scopus 로고
    • Chronic steroid sulfatase inhibition by (p-O-sulfamoyl)-Ntetradecanoyl tyramine increases dehydroepiandrosterone sulfate in whole brain
    • Johnson DA, Rhodes ME, et al. Chronic steroid sulfatase inhibition by (p-O-sulfamoyl)-Ntetradecanoyl tyramine increases dehydroepiandrosterone sulfate in whole brain. Life Sci 1997;61:355-359.
    • (1997) Life Sci , vol.61 , pp. 355-359
    • Johnson, D.A.1    Rhodes, M.E.2
  • 98
    • 0030572961 scopus 로고    scopus 로고
    • Memory enhancement mediated by the steroid sulfatase inhibitor (p-O-sulfamoyl)-N-tetradecanoyl tyramine
    • Li PK, Rhodes ME, et al. Memory enhancement mediated by the steroid sulfatase inhibitor (p-O-sulfamoyl)-N-tetradecanoyl tyramine. Life Sci 1997;60:45-51.
    • (1997) Life Sci , vol.60 , pp. 45-51
    • Li, P.K.1    Rhodes, M.E.2
  • 99
    • 7044233428 scopus 로고    scopus 로고
    • Stress hormones and human memory function across the lifespan
    • Lupien SJ, Fiocco A, Wan N, et al. Stress hormones and human memory function across the lifespan. Psychoneuroendocrinology 2005;30:225-242.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 225-242
    • Lupien, S.J.1    Fiocco, A.2    Wan, N.3
  • 100
    • 0029876892 scopus 로고    scopus 로고
    • Amygdaloid nuclei lesions differentially affect glucocorticoidinduced memory enhancement in an inhibitory avoidance task
    • Roozendaal B, McGaugh JL. Amygdaloid nuclei lesions differentially affect glucocorticoidinduced memory enhancement in an inhibitory avoidance task. Neurobiol Learn Mem 1996;65:1-8.
    • (1996) Neurobiol Learn Mem , vol.65 , pp. 1-8
    • Roozendaal, B.1    McGaugh, J.L.2
  • 101
    • 33646817393 scopus 로고    scopus 로고
    • The neuroactive steroid pregnenolone sulfate stimulates the release of gonadotropin-releasing hormone from GT1-7 hypothalamic neurons, through N-methyl-D-aspartate receptors
    • El-Etr M, Akwa Y, Baulieu EE, Schumacher M. The neuroactive steroid pregnenolone sulfate stimulates the release of gonadotropin-releasing hormone from GT1-7 hypothalamic neurons, through N-methyl-D-aspartate receptors. Endocrinology 2006;147:2737-2743.
    • (2006) Endocrinology , vol.147 , pp. 2737-2743
    • El-Etr, M.1    Akwa, Y.2    Baulieu, E.E.3    Schumacher, M.4
  • 102
    • 0030045509 scopus 로고    scopus 로고
    • The neurosteroid dehydroepiandrosterone sulfate (DHEAS) enhances hippocampal primed burst, but not long-term, potentiation
    • Diamond DM, Branch BJ, et al. The neurosteroid dehydroepiandrosterone sulfate (DHEAS) enhances hippocampal primed burst, but not long-term, potentiation. Neurosci Lett 1996;202:204-208.
    • (1996) Neurosci Lett , vol.202 , pp. 204-208
    • Diamond, D.M.1    Branch, B.J.2
  • 103
    • 0032737985 scopus 로고    scopus 로고
    • Actions of dehydroepiandrosterone and its sulfate in the central nervous system: Effects on cognition and emotion in animals and humans
    • Wolf OT, Kirschbaum C. Actions of dehydroepiandrosterone and its sulfate in the central nervous system: effects on cognition and emotion in animals and humans. Brain Res Rev 1999;30:264-288.
    • (1999) Brain Res Rev , vol.30 , pp. 264-288
    • Wolf, O.T.1    Kirschbaum, C.2
  • 104
    • 0029907749 scopus 로고    scopus 로고
    • High bioavailability of dehydroepiandrosterone administered percutaneously in the rat
    • Labrie C, Flamand M, Belanger A, Labrie F. High bioavailability of dehydroepiandrosterone administered percutaneously in the rat. J Endocrinol 1996;150(Suppl):107-118.
    • (1996) J Endocrinol , vol.150 , Issue.SUPPL. , pp. 107-118
    • Labrie, C.1    Flamand, M.2    Belanger, A.3    Labrie, F.4
  • 105
    • 33646102678 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and its metabolites: Differential effects on androgen receptor trafficking and transcriptional activity
    • Mo Q, Lu SF, et al. Dehydroepiandrosterone and its metabolites: differential effects on androgen receptor trafficking and transcriptional activity. J Steroid Biochem Mol Biol 2006;99:50-58.
    • (2006) J Steroid Biochem Mol Biol , vol.99 , pp. 50-58
    • Mo, Q.1    Lu, S.F.2
  • 106
    • 0011395451 scopus 로고
    • Serum steroid levels in two old men with Alzheimer's disease (AD) before and after oral administration of dehydroepiandrosterone (DHEA). Pregnenolone synthesis may be rate limiting in aging
    • Kalimi M, Regelson W eds, Berlin: de Gruyter
    • Roberts E, Fitten LJ. Serum steroid levels in two old men with Alzheimer's disease (AD) before and after oral administration of dehydroepiandrosterone (DHEA). Pregnenolone synthesis may be rate limiting in aging. In: Kalimi M, Regelson W (eds). The biological role of dehydroepiandrosterone (DHEA). Berlin: de Gruyter, 1990, pp. 43-63.
    • (1990) The Biological Role of Dehydroepiandrosterone (DHEA) , pp. 43-63
    • Roberts, E.1    Fitten, L.J.2
  • 107
    • 0030744143 scopus 로고    scopus 로고
    • Potentially predictive and manipulable blood serum correlates of aging in the healthy human male: Progressive decreases in bioavailable testosterone, dehydroepiandrosterone sulfate, and the ratio of insulin-like growth factor 1 to growth hormone
    • Morley JE, Kaiser F, et al. Potentially predictive and manipulable blood serum correlates of aging in the healthy human male: progressive decreases in bioavailable testosterone, dehydroepiandrosterone sulfate, and the ratio of insulin-like growth factor 1 to growth hormone. Proc Natl Acad Sci USA 1997;94:7537-7542.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 7537-7542
    • Morley, J.E.1    Kaiser, F.2
  • 108
    • 0026629845 scopus 로고    scopus 로고
    • Long-term longitudinal measurements of plasma dehydro-epiandrosterone sulfate in normal men
    • Orentreich N, Brind JL, Vogelman JH, et al. Long-term longitudinal measurements of plasma dehydro-epiandrosterone sulfate in normal men. J Clin Endocrinol Metab 2002;75:1002-1004.
    • (2002) J Clin Endocrinol Metab , vol.75 , pp. 1002-1004
    • Orentreich, N.1    Brind, J.L.2    Vogelman, J.H.3
  • 109
    • 0030739131 scopus 로고    scopus 로고
    • Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging
    • Labrie F, Belanger A, Cusan L, et al. Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging. J Clin Endocrinol Metab 1997;82:2396-2402.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2396-2402
    • Labrie, F.1    Belanger, A.2    Cusan, L.3
  • 110
    • 0032055231 scopus 로고    scopus 로고
    • Longitudinal changes in dehydroepiandrosterone concentrations in men and women
    • Nafziger AN, Bowlin SJ, et al. Longitudinal changes in dehydroepiandrosterone concentrations in men and women. J Lab Clin Med 1998;131:316-323.
    • (1998) J Lab Clin Med , vol.131 , pp. 316-323
    • Nafziger, A.N.1    Bowlin, S.J.2
  • 111
    • 0024264898 scopus 로고
    • Dehydroepiandrosterone sulphate and dehydroepiandrosterone in serum: Differences related to age and sex
    • Carlström K, Brody S, Lunell N-O, et al. Dehydroepiandrosterone sulphate and dehydroepiandrosterone in serum: differences related to age and sex. Maturitas 1988;10:297-306.
    • (1988) Maturitas , vol.10 , pp. 297-306
    • Carlström, K.1    Brody, S.2    Lunell, N.-O.3
  • 112
    • 0021181906 scopus 로고
    • Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
    • Orentreich N, Brind JL, Rizer RL, et al. Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J Clin Endocrinol Metab 1984;59:551-555.
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 551-555
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3
  • 113
    • 0018926253 scopus 로고
    • Sex difference in the metabolism of dehydroisoandrosterone sulfate
    • Zumoff B, Bradlow HL. Sex difference in the metabolism of dehydroisoandrosterone sulfate. J Clin Endocrinol Metab 1980;51:334-336.
    • (1980) J Clin Endocrinol Metab , vol.51 , pp. 334-336
    • Zumoff, B.1    Bradlow, H.L.2
  • 114
    • 1342307975 scopus 로고    scopus 로고
    • Dehydroepiandrosterone sulfate (DHEAS) and health: Does the relationship differ by sex?
    • Glei DA, Goldman N, Weinstein M, Liu IW. Dehydroepiandrosterone sulfate (DHEAS) and health: does the relationship differ by sex? Exp Gerontol 2004;39:321-331.
    • (2004) Exp Gerontol , vol.39 , pp. 321-331
    • Glei, D.A.1    Goldman, N.2    Weinstein, M.3    Liu, I.W.4
  • 115
    • 0001325926 scopus 로고
    • Identification and isolation of dehydroisoandrosterone from peripheral human plasma
    • Migeon CJ, Plager JE. Identification and isolation of dehydroisoandrosterone from peripheral human plasma. J Biol Chem 1954;209:767-772.
    • (1954) J Biol Chem , vol.209 , pp. 767-772
    • Migeon, C.J.1    Plager, J.E.2
  • 116
    • 0029798422 scopus 로고    scopus 로고
    • Cortisol, dehydroepiandrosterone (DHEA), and DHEA sulfate in the cerebrospinal fluid of man: Relation to blood levels and the effects of age
    • Guazzo EP, Kirkpatrick PJ, et al. Cortisol, dehydroepiandrosterone (DHEA), and DHEA sulfate in the cerebrospinal fluid of man: relation to blood levels and the effects of age. J Clin Endocrinol Metab 1996;81:3951-3960.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3951-3960
    • Guazzo, E.P.1    Kirkpatrick, P.J.2
  • 117
    • 33751177773 scopus 로고    scopus 로고
    • Heritability of dehydroepiandrosterone sulfate in women with polycystic ovary syndrome and their sisters
    • Yildiz BO, Goodarzi MO, et al. Heritability of dehydroepiandrosterone sulfate in women with polycystic ovary syndrome and their sisters. Fertil Steril 2006;86:1688-1693.
    • (2006) Fertil Steril , vol.86 , pp. 1688-1693
    • Yildiz, B.O.1    Goodarzi, M.O.2
  • 118
    • 0031968163 scopus 로고    scopus 로고
    • Low dehydroepiandrosterone sulfate and heart disease in middle-aged men: Cross-sectional results from the Massachusetts Male Aging Study
    • Feldman HA, Johannes CB, et al. Low dehydroepiandrosterone sulfate and heart disease in middle-aged men: cross-sectional results from the Massachusetts Male Aging Study. Ann Epidemiol 1998;8:217-228.
    • (1998) Ann Epidemiol , vol.8 , pp. 217-228
    • Feldman, H.A.1    Johannes, C.B.2
  • 119
    • 0035155366 scopus 로고    scopus 로고
    • Low dehydroepiandrosterone and ischemic heart disease in middle-aged men: Prospective results from the Massachusetts male aging study
    • Feldman HA, Johannes CB, et al. Low dehydroepiandrosterone and ischemic heart disease in middle-aged men: prospective results from the Massachusetts male aging study. Am J Epidemiol 2001;153:79-89.
    • (2001) Am J Epidemiol , vol.153 , pp. 79-89
    • Feldman, H.A.1    Johannes, C.B.2
  • 120
    • 0034993140 scopus 로고    scopus 로고
    • Salivary cortisol and DHEA: Association with measures of cognition and well-being in normal older men, and effects of three months of DHEA supplementation
    • Van Niekerk JK, Huppert FA, et al. Salivary cortisol and DHEA: association with measures of cognition and well-being in normal older men, and effects of three months of DHEA supplementation. Psychoneuroendocrinology 2001;26:591-612.
    • (2001) Psychoneuroendocrinology , vol.26 , pp. 591-612
    • Van Niekerk, J.K.1    Huppert, F.A.2
  • 121
    • 0030025446 scopus 로고    scopus 로고
    • Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and noninsulin-dependent diabetes in postmenopausal women: The Rancho Bernardo Study
    • Barrett-Connor E, Ferrara A. Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and noninsulin-dependent diabetes in postmenopausal women: the Rancho Bernardo Study. J Clin Endocrinol Metab 1996;81:59-64.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 59-64
    • Barrett-Connor, E.1    Ferrara, A.2
  • 122
    • 33746564555 scopus 로고    scopus 로고
    • Fatigue in progressive multiple sclerosis is associated with low levels of dehydroepiandrosterone
    • Tellez N, Comabella M, et al. Fatigue in progressive multiple sclerosis is associated with low levels of dehydroepiandrosterone. Mult Scler 2006;12:487-494.
    • (2006) Mult Scler , vol.12 , pp. 487-494
    • Tellez, N.1    Comabella, M.2
  • 123
    • 33745782274 scopus 로고    scopus 로고
    • Low serum levels of DHEAS in untreated polymyalgia rheumatica/giant cell arteritis
    • Narvaez J, Bernad B, et al. Low serum levels of DHEAS in untreated polymyalgia rheumatica/giant cell arteritis. J Rheumatol 2006;33:1293-1298.
    • (2006) J Rheumatol , vol.33 , pp. 1293-1298
    • Narvaez, J.1    Bernad, B.2
  • 124
    • 0035657619 scopus 로고    scopus 로고
    • Dehydroepiandrosterone sulphate is increased and dehydroepiandrosterone- response to corticotrophin-releasing hormone is decreased in the hyperthyroid state compared with the euthyroid state
    • Yamakita N, Murai T, Kokubo Y, et al. Dehydroepiandrosterone sulphate is increased and dehydroepiandrosterone-response to corticotrophin-releasing hormone is decreased in the hyperthyroid state compared with the euthyroid state. Clin Endocrinol (Oxf) 2001;55:797-803.
    • (2001) Clin Endocrinol (Oxf) , vol.55 , pp. 797-803
    • Yamakita, N.1    Murai, T.2    Kokubo, Y.3
  • 125
    • 0031925170 scopus 로고    scopus 로고
    • Endocrine mechanisms of stress-induced DHEAsecretion
    • Oberbeck R, Benschop RJ, Jacobs R, et al. Endocrine mechanisms of stress-induced DHEAsecretion. J Endocrinol Invest 1998;21:148-153.
    • (1998) J Endocrinol Invest , vol.21 , pp. 148-153
    • Oberbeck, R.1    Benschop, R.J.2    Jacobs, R.3
  • 126
    • 3543139554 scopus 로고    scopus 로고
    • Relationships among plasma dehydroepiandrosterone sulfate and cortisol levels, symptoms of dissociation, and objective performance in humans exposed to acute stress
    • Morgan CA 3rd, Southwick S, Hazlett G, et al. Relationships among plasma dehydroepiandrosterone sulfate and cortisol levels, symptoms of dissociation, and objective performance in humans exposed to acute stress. Arch Gen Psychiatry 2004;61:819-825.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 819-825
    • Morgan III, C.A.1    Southwick, S.2    Hazlett, G.3
  • 127
    • 0033626831 scopus 로고    scopus 로고
    • Elevated circulatory level of GABA (A) - Antagonistic neurosteroids in patients with combat-related post-traumatic stress disorder
    • Spivak B, Maayan R, Kotler M, et al. Elevated circulatory level of GABA (A) - antagonistic neurosteroids in patients with combat-related post-traumatic stress disorder. Psychol Med 2000;30:1227-1231.
    • (2000) Psychol Med , vol.30 , pp. 1227-1231
    • Spivak, B.1    Maayan, R.2    Kotler, M.3
  • 128
    • 0035145064 scopus 로고    scopus 로고
    • Plasma levels of neuroactive steroids are increased in untreated women with anorexia nervosa or bulimia nervosa
    • Monteleone P, Luisi M, Colurcio B, et al. Plasma levels of neuroactive steroids are increased in untreated women with anorexia nervosa or bulimia nervosa. Psychosom Med 2001;63:62-68.
    • (2001) Psychosom Med , vol.63 , pp. 62-68
    • Monteleone, P.1    Luisi, M.2    Colurcio, B.3
  • 129
    • 33746407508 scopus 로고    scopus 로고
    • Clinical correlates of DHEA associated with post-traumatic stress disorder
    • Yehuda R, Brand SR, Golier JA, Yang RK. Clinical correlates of DHEA associated with post-traumatic stress disorder. Acta Psychiatr Scand 2006;114:187-193.
    • (2006) Acta Psychiatr Scand , vol.114 , pp. 187-193
    • Yehuda, R.1    Brand, S.R.2    Golier, J.A.3    Yang, R.K.4
  • 131
    • 33644872993 scopus 로고    scopus 로고
    • Impaired reduction of enhanced levels of dehydroepiandrosterone by oral dexamethasone in anorexia nervosa
    • Monteleone P, Luisi M, Martiadis V, et al. Impaired reduction of enhanced levels of dehydroepiandrosterone by oral dexamethasone in anorexia nervosa. Psychoneuroendocrinology 2006;31:537-542.
    • (2006) Psychoneuroendocrinology , vol.31 , pp. 537-542
    • Monteleone, P.1    Luisi, M.2    Martiadis, V.3
  • 132
    • 1942445189 scopus 로고    scopus 로고
    • Levels of DHEA and DHEAS and responses to CRH stimulation and hydrocortisone treatment in chronic fatigue syndrome
    • Cleare AJ, O'Keane V, et al. Levels of DHEA and DHEAS and responses to CRH stimulation and hydrocortisone treatment in chronic fatigue syndrome. Psychoneuroendocrinology 2004;29:724-732.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 724-732
    • Cleare, A.J.1    O'Keane, V.2
  • 133
    • 0028234068 scopus 로고
    • CSF neuroactive steroids in affective disorders: Pregnenolone, progesterone, and DBI
    • George MS, Guidotti A, Rubinow D, et al. CSF neuroactive steroids in affective disorders: pregnenolone, progesterone, and DBI. Biol Psychiatry 1994;35:775-780.
    • (1994) Biol Psychiatry , vol.35 , pp. 775-780
    • George, M.S.1    Guidotti, A.2    Rubinow, D.3
  • 134
    • 0034519350 scopus 로고    scopus 로고
    • Serum concentrations of some neuroactive steroids in women suffering from mixed anxiety-depressive disorder
    • Bicikova M, Tallova J, Hill M, et al. Serum concentrations of some neuroactive steroids in women suffering from mixed anxiety-depressive disorder. Neurochem Res 2000;25:1623-1627.
    • (2000) Neurochem Res , vol.25 , pp. 1623-1627
    • Bicikova, M.1    Tallova, J.2    Hill, M.3
  • 136
    • 0036020868 scopus 로고    scopus 로고
    • Low pregnenolone sulphate plasma concentrations in patients with generalized social phobia
    • Heydari B, Le Melledo JM. Low pregnenolone sulphate plasma concentrations in patients with generalized social phobia. Psychol Med 2002;32:929-933.
    • (2002) Psychol Med , vol.32 , pp. 929-933
    • Heydari, B.1    Le Melledo, J.M.2
  • 137
    • 0034034239 scopus 로고    scopus 로고
    • Serum dehydroepiandrosterone, dehydroepiandrosterone sulfate, and pregnenolone sulfate concentrations in patients with hyperthyroidism and hypothyroidism
    • Tagawa N, Tamanaka J, et al. Serum dehydroepiandrosterone, dehydroepiandrosterone sulfate, and pregnenolone sulfate concentrations in patients with hyperthyroidism and hypothyroidism. Clin Chem 2000;46:523-528.
    • (2000) Clin Chem , vol.46 , pp. 523-528
    • Tagawa, N.1    Tamanaka, J.2
  • 138
    • 19344365160 scopus 로고    scopus 로고
    • Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction
    • Hill M, Popov P, et al. Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction. Steroids 2005;70:515-524.
    • (2005) Steroids , vol.70 , pp. 515-524
    • Hill, M.1    Popov, P.2
  • 139
    • 0031880164 scopus 로고    scopus 로고
    • Plasma dehydroepiandrosterone sulfate in unipolar major depression. Short communication
    • Takebayashi M, Kagaya A, Uchitomi Y, et al. Plasma dehydroepiandrosterone sulfate in unipolar major depression. Short communication. J Neural Transm 1998;105:537-542.
    • (1998) J Neural Transm , vol.105 , pp. 537-542
    • Takebayashi, M.1    Kagaya, A.2    Uchitomi, Y.3
  • 140
    • 0031797337 scopus 로고    scopus 로고
    • Increased diurnal plasma concentrations of dehydroepiandrosterone in depressed patients
    • Heuser I, Deuschle M, Luppa P, et al. Increased diurnal plasma concentrations of dehydroepiandrosterone in depressed patients. J Clin Endocrinol Metab 1998;83:3130-3133.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3130-3133
    • Heuser, I.1    Deuschle, M.2    Luppa, P.3
  • 141
    • 0034306897 scopus 로고    scopus 로고
    • Basal plasma dehydroepiandrosterone sulfate level: A possible predictor for response to electroconvulsive therapy in depressed psychotic inpatients
    • Maayan R, Yagorowski Y, Grupper D, et al. Basal plasma dehydroepiandrosterone sulfate level: a possible predictor for response to electroconvulsive therapy in depressed psychotic inpatients. Biol Psychiatry 2000;48:693-701.
    • (2000) Biol Psychiatry , vol.48 , pp. 693-701
    • Maayan, R.1    Yagorowski, Y.2    Grupper, D.3
  • 142
    • 0034669404 scopus 로고    scopus 로고
    • Altered salivary dehydroepiandrosterone levels in major depression in adults
    • Michael A, Jenaway A, Paykel ES, Herbert J. Altered salivary dehydroepiandrosterone levels in major depression in adults. Biol Psychiatry 2000;48:989-995.
    • (2000) Biol Psychiatry , vol.48 , pp. 989-995
    • Michael, A.1    Jenaway, A.2    Paykel, E.S.3    Herbert, J.4
  • 143
    • 33744473309 scopus 로고    scopus 로고
    • Cortisol and DHEA-S are associated with startle potentiation during aversive conditioning in humans
    • Grillon C, Pine DS, Baas JM, et al. Cortisol and DHEA-S are associated with startle potentiation during aversive conditioning in humans. Psychopharmacology (Berl.) 2006;186:434-441.
    • (2006) Psychopharmacology (Berl.) , vol.186 , pp. 434-441
    • Grillon, C.1    Pine, D.S.2    Baas, J.M.3
  • 144
    • 0032998119 scopus 로고    scopus 로고
    • Cognitive-behavioral stress management buffers decreases in dehydroepiandrosterone sulfate (DHEA-S) and increases in the cortisol/DHEAS ratio and reduces mood disturbance and perceived stress among HIV-seropositive men
    • Cruess DG, Antoni MH, Kumar M, et al. Cognitive-behavioral stress management buffers decreases in dehydroepiandrosterone sulfate (DHEA-S) and increases in the cortisol/DHEAS ratio and reduces mood disturbance and perceived stress among HIV-seropositive men. Psychoneuroendocrinology 1999;24:537-549.
    • (1999) Psychoneuroendocrinology , vol.24 , pp. 537-549
    • Cruess, D.G.1    Antoni, M.H.2    Kumar, M.3
  • 145
    • 33751219241 scopus 로고    scopus 로고
    • Adrenal androgen and gonadal hormone levels in adolescent girls with conduct disorder
    • Pajer K, Tabbah R, Gardner W, et al. Adrenal androgen and gonadal hormone levels in adolescent girls with conduct disorder. Psychoneuroendocrinology 2006;31:1245-1256.
    • (2006) Psychoneuroendocrinology , vol.31 , pp. 1245-1256
    • Pajer, K.1    Tabbah, R.2    Gardner, W.3
  • 146
    • 0027263366 scopus 로고
    • Adrenal androgens and cortisol in major depression
    • Osran H, Reist C, Chen CC, et al. Adrenal androgens and cortisol in major depression. Am J Psychiatry 1993;150:806-809.
    • (1993) Am J Psychiatry , vol.150 , pp. 806-809
    • Osran, H.1    Reist, C.2    Chen, C.C.3
  • 147
    • 0032995191 scopus 로고    scopus 로고
    • Differences in adrenal steroid profile in chronic fatigue syndrome, in depression and in health
    • Scott LV, Salahuddin F, Cooney J, et al. Differences in adrenal steroid profile in chronic fatigue syndrome, in depression and in health. J Affect Disord 1999;54:129-137.
    • (1999) J Affect Disord , vol.54 , pp. 129-137
    • Scott, L.V.1    Salahuddin, F.2    Cooney, J.3
  • 149
    • 0035890668 scopus 로고    scopus 로고
    • Endogenous concentrations of DHEA and DHEA-S decrease with remission of depression in older adults
    • Fabian TJ, Dew MA, Pollock BG, et al. Endogenous concentrations of DHEA and DHEA-S decrease with remission of depression in older adults. Biol Psychiatry 2001;50:767-774.
    • (2001) Biol Psychiatry , vol.50 , pp. 767-774
    • Fabian, T.J.1    Dew, M.A.2    Pollock, B.G.3
  • 150
    • 0029995191 scopus 로고    scopus 로고
    • Adrenal secretion during major depression in 8-to 16-yearolds. I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation
    • Goodyer IM, Herbert J, et al. Adrenal secretion during major depression in 8-to 16-yearolds. I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation. Psychol Med 1996;26:245-256.
    • (1996) Psychol Med , vol.26 , pp. 245-256
    • Goodyer, I.M.1    Herbert, J.2
  • 151
    • 0036300974 scopus 로고    scopus 로고
    • Elevation of the cortisol-dehydroepiandrosterone ratio in drug-free depressed patients
    • Young AH, Gallagher P, Porter RJ. Elevation of the cortisol- dehydroepiandrosterone ratio in drug-free depressed patients. Am J Psychiatry 2002;159:1237-1239.
    • (2002) Am J Psychiatry , vol.159 , pp. 1237-1239
    • Young, A.H.1    Gallagher, P.2    Porter, R.J.3
  • 152
    • 0038751899 scopus 로고    scopus 로고
    • Psychoendocrine antecedents of persistent first-episode major depression in adolescents: A community-based longitudinal enquiry
    • Goodyer IM, Herbert J, Tamplin A. Psychoendocrine antecedents of persistent first-episode major depression in adolescents: a community-based longitudinal enquiry. Psychol Med 2003;33:601-610.
    • (2003) Psychol Med , vol.33 , pp. 601-610
    • Goodyer, I.M.1    Herbert, J.2    Tamplin, A.3
  • 153
    • 3042636200 scopus 로고    scopus 로고
    • Cognitive and affective disorders in the elderly: A neuroendocrine study
    • Ferrari E, Mirani M, et al. Cognitive and affective disorders in the elderly: a neuroendocrine study. Arch Gerontol Geriatr 2004 (Suppl 9):171-182.
    • (2004) Arch Gerontol Geriatr , Issue.SUPPL. 9 , pp. 171-182
    • Ferrari, E.1    Mirani, M.2
  • 155
    • 33644832580 scopus 로고    scopus 로고
    • Cortisol, the cortisol-dehydroepiandrosterone ratio, and pro-inflammatory cytokines in patients with current major depressive disorder comorbid with borderline personality disorder
    • Kahl KG, Bens S, Ziegler K, et al. Cortisol, the cortisol- dehydroepiandrosterone ratio, and pro-inflammatory cytokines in patients with current major depressive disorder comorbid with borderline personality disorder. Biol Psychiatry 2006;59:667-671.
    • (2006) Biol Psychiatry , vol.59 , pp. 667-671
    • Kahl, K.G.1    Bens, S.2    Ziegler, K.3
  • 156
    • 0036924873 scopus 로고    scopus 로고
    • Cortisol and dehydroepiandosterone sulfate plasma levels and their relationship to aging, cognitive function, and dementia
    • De Bruin VM, Vieira MC, Rocha MN, Viana GS. Cortisol and dehydroepiandosterone sulfate plasma levels and their relationship to aging, cognitive function, and dementia. Brain Cogn 2002;50:316-323.
    • (2002) Brain Cogn , vol.50 , pp. 316-323
    • De Bruin, V.M.1    Vieira, M.C.2    Rocha, M.N.3    Viana, G.S.4
  • 157
    • 0033670260 scopus 로고    scopus 로고
    • Changes in cortisol/DHEA ratio in HIV-infected men are related to immunological and metabolic perturbations leading to malnutrition and lipodystrophy
    • Christeff N, Nunez EA, Gougeon ML. Changes in cortisol/DHEA ratio in HIV-infected men are related to immunological and metabolic perturbations leading to malnutrition and lipodystrophy. Ann NY Acad Sci 2000;917:962-970.
    • (2000) Ann NY Acad Sci , vol.917 , pp. 962-970
    • Christeff, N.1    Nunez, E.A.2    Gougeon, M.L.3
  • 158
    • 0020586346 scopus 로고
    • Cortisol, estradiol, and androgens in acutely ill paranoid schizophrenics
    • Brophy MH, Rush AJ, Crowley G. Cortisol, estradiol, and androgens in acutely ill paranoid schizophrenics. Biol Psychiatry 1983;18:583-590.
    • (1983) Biol Psychiatry , vol.18 , pp. 583-590
    • Brophy, M.H.1    Rush, A.J.2    Crowley, G.3
  • 159
    • 0035324285 scopus 로고    scopus 로고
    • Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patients
    • Harris DS, Wolkowitz OM, Reus VI. Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patients. World J Biol Psychiatry 2001;2:99-102.
    • (2001) World J Biol Psychiatry , vol.2 , pp. 99-102
    • Harris, D.S.1    Wolkowitz, O.M.2    Reus, V.I.3
  • 160
    • 14544281889 scopus 로고    scopus 로고
    • Negative correlation between negative symptoms of schizophrenia and testosterone levels
    • Goyal RO, Sagar R, Ammini AC, et al. Negative correlation between negative symptoms of schizophrenia and testosterone levels. Ann NY Acad Sci 2004;1032:291-294.
    • (2004) Ann NY Acad Sci , vol.1032 , pp. 291-294
    • Goyal, R.O.1    Sagar, R.2    Ammini, A.C.3
  • 161
    • 2442612542 scopus 로고    scopus 로고
    • Elevation of the cortisol/dehydroepiandrosterone ratio in schizophrenia patients
    • Ritsner M, Maayan R, Gibel A, et al. Elevation of the cortisol/dehydroepiandrosterone ratio in schizophrenia patients. Eur Neuropsychopharmacol 2004;14:267-273.
    • (2004) Eur Neuropsychopharmacol , vol.14 , pp. 267-273
    • Ritsner, M.1    Maayan, R.2    Gibel, A.3
  • 162
    • 33847058371 scopus 로고    scopus 로고
    • Increased levels of nitric oxide, cortisol and adrenomedullin in patients with chronic schizophrenia
    • Yilmaz N, Herken H, Cicek HK, et al. Increased levels of nitric oxide, cortisol and adrenomedullin in patients with chronic schizophrenia. Med Princ Pract 2007;16:137-141.
    • (2007) Med Princ Pract , vol.16 , pp. 137-141
    • Yilmaz, N.1    Herken, H.2    Cicek, H.K.3
  • 163
    • 0015463198 scopus 로고
    • Plasma androgens in male schizophrenics
    • Tourney G, Hatfield L. Plasma androgens in male schizophrenics. Arch Gen Psychiatry 1972;27:753-755.
    • (1972) Arch Gen Psychiatry , vol.27 , pp. 753-755
    • Tourney, G.1    Hatfield, L.2
  • 164
    • 0016393724 scopus 로고
    • Interaction between dehydroepiandrosterone, cyclic adenosine-3', 5'-monophosphate and glucose-6-phosphate-dehydrogenase in normal and diseased subjects
    • Oertel GW, Benes P, Schirazi M, et al. Interaction between dehydroepiandrosterone, cyclic adenosine-3', 5'-monophosphate and glucose-6-phosphate-dehydrogenase in normal and diseased subjects. Experientia 1974;30:872-873.
    • (1974) Experientia , vol.30 , pp. 872-873
    • Oertel, G.W.1    Benes, P.2    Schirazi, M.3
  • 165
    • 0028217596 scopus 로고
    • Serum gonadal steroid hormones in young schizophrenic patients
    • Oades RD, Schepker R. Serum gonadal steroid hormones in young schizophrenic patients. Psychoneuroendocrinology 1994;19:373-385.
    • (1994) Psychoneuroendocrinology , vol.19 , pp. 373-385
    • Oades, R.D.1    Schepker, R.2
  • 166
    • 4944263865 scopus 로고    scopus 로고
    • Increased circulatory dehydroepiandrosterone and dehydroepiandrosterone- sulphate in first-episode schizophrenia: Relationship to gender, aggression and symptomatology
    • Strous RD, Maayan R, Lapidus R, et al. Increased circulatory dehydroepiandrosterone and dehydroepiandrosterone-sulphate in first-episode schizophrenia: relationship to gender, aggression and symptomatology. Schizophr Res 2004;71:427-434.
    • (2004) Schizophr Res , vol.71 , pp. 427-434
    • Strous, R.D.1    Maayan, R.2    Lapidus, R.3
  • 167
    • 13844253774 scopus 로고    scopus 로고
    • Plasma dehydroepiandrosterone levels are strongly increased in schizophrenia
    • Di Michele F, Caltagirone C, Bonaviri G, et al. Plasma dehydroepiandrosterone levels are strongly increased in schizophrenia. J Psychiatr Res 2005;39:267-273.
    • (2005) J Psychiatr Res , vol.39 , pp. 267-273
    • Di Michele, F.1    Caltagirone, C.2    Bonaviri, G.3
  • 168
    • 31344435293 scopus 로고    scopus 로고
    • Alterations in DHEA metabolism in schizophrenia: Twomonth case-control study
    • Ritsner M, Gibel A, Ram E, et al. Alterations in DHEA metabolism in schizophrenia: twomonth case-control study. Eur Neuropsychopharmacol 2006;16:137-146.
    • (2006) Eur Neuropsychopharmacol , vol.16 , pp. 137-146
    • Ritsner, M.1    Gibel, A.2    Ram, E.3
  • 169
    • 33846643951 scopus 로고    scopus 로고
    • Plasma cortisol-dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder
    • Gallagher P, Watson S, Smith MS, et al. Plasma cortisol- dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder. Schizophr Res 2007;90:258-265.
    • (2007) Schizophr Res , vol.90 , pp. 258-265
    • Gallagher, P.1    Watson, S.2    Smith, M.S.3
  • 170
    • 0018385016 scopus 로고
    • Temporal variations in androgens and stress hormones in control and schizophrenic subjects
    • Tourney G, Erb JL. Temporal variations in androgens and stress hormones in control and schizophrenic subjects. Biol Psychiatry 1979;14:395-404.
    • (1979) Biol Psychiatry , vol.14 , pp. 395-404
    • Tourney, G.1    Erb, J.L.2
  • 171
    • 0019352093 scopus 로고
    • Discrimination between schizophrenic and control subjects by means of plasma dehydroepiandrosterone measurements
    • Erb JL, Kadane JB, Tourney G, et al. Discrimination between schizophrenic and control subjects by means of plasma dehydroepiandrosterone measurements. J Clin Endocrinol Metab 1981;52:181-186.
    • (1981) J Clin Endocrinol Metab , vol.52 , pp. 181-186
    • Erb, J.L.1    Kadane, J.B.2    Tourney, G.3
  • 172
    • 33846402115 scopus 로고    scopus 로고
    • State and trait related predictors of serum cortisol to DHEA (S) molar ratios and hormone concentrations in schizophrenia patients
    • Ritsner M, Gibel A, Maayan R, et al. State and trait related predictors of serum cortisol to DHEA (S) molar ratios and hormone concentrations in schizophrenia patients. Eur Neuropsychopharmacol 2007;17:257-264.
    • (2007) Eur Neuropsychopharmacol , vol.17 , pp. 257-264
    • Ritsner, M.1    Gibel, A.2    Maayan, R.3
  • 175
    • 23844530899 scopus 로고    scopus 로고
    • Cortisol and cytokines in chronic and treatment-resistant patients with schizophrenia: Association with psychopathology and response to antipsychotics
    • Zhang XY, Zhou DF, Cao LY, et al. Cortisol and cytokines in chronic and treatment-resistant patients with schizophrenia: association with psychopathology and response to antipsychotics. Neuropsychopharmacology 2005;30:1532-1538.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1532-1538
    • Zhang, X.Y.1    Zhou, D.F.2    Cao, L.Y.3
  • 176
    • 0036592395 scopus 로고    scopus 로고
    • The hypothalamic-pituitary-adrenal axis in chronic schizophrenic patients long-term treated with neuroleptics
    • Kaneda Y, Fujii A, Ohmori T. The hypothalamic-pituitary-adrenal axis in chronic schizophrenic patients long-term treated with neuroleptics. Prog Neuropsychopharmacol Biol Psychiatry 2002;26:935-938.
    • (2002) Prog Neuropsychopharmacol Biol Psychiatry , vol.26 , pp. 935-938
    • Kaneda, Y.1    Fujii, A.2    Ohmori, T.3
  • 177
    • 16544373298 scopus 로고    scopus 로고
    • Evaluation of serum steroid hormones in schizophrenic patients
    • Taherianfard M, Shariaty M. Evaluation of serum steroid hormones in schizophrenic patients. Indian J Med Sci 2004;58:3-9.
    • (2004) Indian J Med Sci , vol.58 , pp. 3-9
    • Taherianfard, M.1    Shariaty, M.2
  • 178
    • 0033590278 scopus 로고    scopus 로고
    • Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations
    • Heinz A, Weingartner H, George D, et al. Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations. Psychiatry Res 1999;89:97-106.
    • (1999) Psychiatry Res , vol.89 , pp. 97-106
    • Heinz, A.1    Weingartner, H.2    George, D.3
  • 179
    • 0036842387 scopus 로고    scopus 로고
    • Correlation of plasma neurosteroid levels to the severity of negative symptoms in male patients with schizophrenia
    • Shirayama Y, Hashimoto K, Suzuki Y, Higuchi T. Correlation of plasma neurosteroid levels to the severity of negative symptoms in male patients with schizophrenia. Schizophr Res 2002;58:69-74.
    • (2002) Schizophr Res , vol.58 , pp. 69-74
    • Shirayama, Y.1    Hashimoto, K.2    Suzuki, Y.3    Higuchi, T.4
  • 180
    • 33750947320 scopus 로고    scopus 로고
    • Positive correlation between anxiety severity and plasma levels of dehydroepiandrosterone sulfate in medication-free patients experiencing a major episode of depression
    • Hsiao CC. Positive correlation between anxiety severity and plasma levels of dehydroepiandrosterone sulfate in medication-free patients experiencing a major episode of depression. Psychiatry Clin Neurosci 2006;60:746-750.
    • (2006) Psychiatry Clin Neurosci , vol.60 , pp. 746-750
    • Hsiao, C.C.1
  • 181
    • 0037312851 scopus 로고    scopus 로고
    • Dehydroepiandrosterone augmentation in the management of negative, depressive, and anxiety symptoms in schizophrenia
    • Strous RD, Maayan R, Lapidus R, et al. Dehydroepiandrosterone augmentation in the management of negative, depressive, and anxiety symptoms in schizophrenia. Arch Gen Psychiatry 2003;60:133-141.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 133-141
    • Strous, R.D.1    Maayan, R.2    Lapidus, R.3
  • 182
    • 33847048555 scopus 로고    scopus 로고
    • Analysis of clinical symptomatology, extrapyramidal symptoms and neurocognitive dysfunction following dehydroepiandrosterone (DHEA) administration in olanzapine treated schizophrenia patients: A randomized, double-blind placebo controlled trial
    • Strous RD, Stryjer R, Maayan R, et al. Analysis of clinical symptomatology, extrapyramidal symptoms and neurocognitive dysfunction following
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 96-105
    • Strous, R.D.1    Stryjer, R.2    Maayan, R.3
  • 183
    • 33748745743 scopus 로고    scopus 로고
    • Improvement of sustained attention and visual and movement skills, but not clinical symptoms, after dehydroepiandrosterone augmentation in schizophrenia: A randomized, double-blind, placebo-controlled, crossover trial
    • Ritsner MS, Gibel A, Ratner Y, et al. Improvement of sustained attention and visual and movement skills, but not clinical symptoms, after dehydroepiandrosterone augmentation in schizophrenia: a randomized, double-blind, placebo-controlled, crossover trial. J Clin Psychopharmacol 2006;26:495-499.
    • (2006) J Clin Psychopharmacol , vol.26 , pp. 495-499
    • Ritsner, M.S.1    Gibel, A.2    Ratner, Y.3
  • 184
    • 33847216593 scopus 로고    scopus 로고
    • Differences in blood pregnenolone and dehydroepiandrosterone levels between schizophrenia patients and healthy subjects
    • Ritsner M, Maayan R, Gibel A, Weizman A. Differences in blood pregnenolone and dehydroepiandrosterone levels between schizophrenia patients and healthy subjects. Eur Neuropsychopharmacol 2007;17:358-365.
    • (2007) Eur Neuropsychopharmacol , vol.17 , pp. 358-365
    • Ritsner, M.1    Maayan, R.2    Gibel, A.3    Weizman, A.4
  • 185
    • 0030980583 scopus 로고    scopus 로고
    • Neuropsychological evidence supporting a neurodevelopmental model of schizophrenia: A longitudinal study
    • Censits DM, Ragland JD, Gur RC, Gur RE. Neuropsychological evidence supporting a neurodevelopmental model of schizophrenia: a longitudinal study. Schizophr Res 1997;24:289-298.
    • (1997) Schizophr Res , vol.24 , pp. 289-298
    • Censits, D.M.1    Ragland, J.D.2    Gur, R.C.3    Gur, R.E.4
  • 186
    • 17044406214 scopus 로고    scopus 로고
    • The primacy of cognition in schizophrenia
    • Heinrichs RW. The primacy of cognition in schizophrenia. Am Psychol 2005;60:229-242.
    • (2005) Am Psychol , vol.60 , pp. 229-242
    • Heinrichs, R.W.1
  • 187
    • 0031978625 scopus 로고    scopus 로고
    • Executive function in first-episode schizophrenia
    • Hutton SB, Puri BK, Duncan LJ, et al. Executive function in first-episode schizophrenia. Psychol Med 1998;28:463-473.
    • (1998) Psychol Med , vol.28 , pp. 463-473
    • Hutton, S.B.1    Puri, B.K.2    Duncan, L.J.3
  • 188
    • 0035165195 scopus 로고    scopus 로고
    • Stability of olfactory identification deficits in neurolepticnaive patients with first-episode psychosis
    • Brewer WJ, Pantelis C, Anderson V, et al. Stability of olfactory identification deficits in neurolepticnaive patients with first-episode psychosis. Am J Psychiatry 2001;158:107-115.
    • (2001) Am J Psychiatry , vol.158 , pp. 107-115
    • Brewer, W.J.1    Pantelis, C.2    Anderson, V.3
  • 189
    • 0031846542 scopus 로고    scopus 로고
    • A review of longitudinal studies of cognitive functions in schizophrenia patients
    • Rund BR. A review of longitudinal studies of cognitive functions in schizophrenia patients. Schizophr Bull 1998;24:425-435.
    • (1998) Schizophr Bull , vol.24 , pp. 425-435
    • Rund, B.R.1
  • 190
    • 23944435882 scopus 로고    scopus 로고
    • Ten year longitudinal study of neuropsychological functioning subsequent to a first episode of schizophrenia
    • Hoff AL, Svetina C, Shields G, et al. Ten year longitudinal study of neuropsychological functioning subsequent to a first episode of schizophrenia. Schizophr Res 2005;78:27-34.
    • (2005) Schizophr Res , vol.78 , pp. 27-34
    • Hoff, A.L.1    Svetina, C.2    Shields, G.3
  • 191
    • 33749645423 scopus 로고    scopus 로고
    • Cognitive dysfunction in schizophrenia: Convergence of gammaaminobutyric acid and glutamate alterations
    • Lewis DA, Moghaddam B. Cognitive dysfunction in schizophrenia: convergence of gammaaminobutyric acid and glutamate alterations. Arch Neurol 2006;63:1372-1376.
    • (2006) Arch Neurol , vol.63 , pp. 1372-1376
    • Lewis, D.A.1    Moghaddam, B.2
  • 192
    • 33747404243 scopus 로고    scopus 로고
    • Estrogen, cognitive function and negative symptoms in female schizophrenia
    • Ko YH, Joe SH, Cho W, et al. Estrogen, cognitive function and negative symptoms in female schizophrenia. Neuropsychobiology 2006;53:169-175.
    • (2006) Neuropsychobiology , vol.53 , pp. 169-175
    • Ko, Y.H.1    Joe, S.H.2    Cho, W.3
  • 193
    • 0031796078 scopus 로고    scopus 로고
    • A prospective study on cortisol, dehydroepiandrosterone sulfate, and cognitive function in the elderly
    • Kalmijn S, Launer LJ, Stolk RP, et al. A prospective study on cortisol, dehydroepiandrosterone sulfate, and cognitive function in the elderly. J Clin Endocrinol Metab 1998;83:3487-3492.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3487-3492
    • Kalmijn, S.1    Launer, L.J.2    Stolk, R.P.3
  • 194
    • 0032406707 scopus 로고    scopus 로고
    • Effects of dehydroepiandrosterone (DHEA) replacement in elderly men on event related potentials (ERPs), memory and wellbeing
    • Wolf OT, Naumann E, Hellhammer DH, Kirschbaum C. Effects of dehydroepiandrosterone (DHEA) replacement in elderly men on event related potentials (ERPs), memory and wellbeing. J Gerontol A Biol Sci Med Sci 1998;53:385-390.
    • (1998) J Gerontol A Biol Sci Med Sci , vol.53 , pp. 385-390
    • Wolf, O.T.1    Naumann, E.2    Hellhammer, D.H.3    Kirschbaum, C.4
  • 195
    • 0032144265 scopus 로고    scopus 로고
    • Opposing effects of DHEA replacement in elderly subjects on declarative memory and attention after exposure to a laboratory stressor
    • Wolf OT, Kudielka BM, Hellhammer DH, et al. Opposing effects of DHEA replacement in elderly subjects on declarative memory and attention after exposure to a laboratory stressor. Psychoneuroendocrinology 1998;23:617-629.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 617-629
    • Wolf, O.T.1    Kudielka, B.M.2    Hellhammer, D.H.3
  • 197
    • 0034710120 scopus 로고    scopus 로고
    • The relationship between longitudinal declines in dehydroepiandrosterone sulfate concentrations and cognitive performance in older men
    • Moffat SD, Zonderman AB, Harman SM, et al. The relationship between longitudinal declines in dehydroepiandrosterone sulfate concentrations and cognitive performance in older men. Arch Intern Med 2000;160:2193-2198.
    • (2000) Arch Intern Med , vol.160 , pp. 2193-2198
    • Moffat, S.D.1    Zonderman, A.B.2    Harman, S.M.3
  • 198
    • 18244398191 scopus 로고    scopus 로고
    • Age, hormones, and cognitive functioning among middle-aged and elderly men: Cross-sectional evidence from the Massachusetts Male Aging Study
    • Fonda SJ, Bertrand R, O'Donnell A, et al. Age, hormones, and cognitive functioning among middle-aged and elderly men: cross-sectional evidence from the Massachusetts Male Aging Study. J Gerontol A Biol Sci Med Sci 2005;60:385-390.
    • (2005) J Gerontol A Biol Sci Med Sci , vol.60 , pp. 385-390
    • Fonda, S.J.1    Bertrand, R.2    O'Donnell, A.3
  • 199
    • 0035071725 scopus 로고    scopus 로고
    • Relationships between cortisol, dehydroepiandrosterone sulphate and insulin-like growth factor-I system in dementia
    • Murialdo G, Barreca A, Nobili F, et al. Relationships between cortisol, dehydroepiandrosterone sulphate and insulin-like growth factor-I system in dementia. J Endocrinol Invest 2001;24:139-146.
    • (2001) J Endocrinol Invest , vol.24 , pp. 139-146
    • Murialdo, G.1    Barreca, A.2    Nobili, F.3
  • 200
    • 0347995011 scopus 로고    scopus 로고
    • Alzheimer's disease: Pathophysiological implications of measurement of plasma cortisol, plasma dehydroepiandrosterone sulfate, and lymphocytic corticosteroid receptors
    • Armanini D, Vecchio F, Basso A, et al. Alzheimer's disease: pathophysiological implications of measurement of plasma cortisol, plasma dehydroepiandrosterone sulfate, and lymphocytic corticosteroid receptors. Endocrine 2003;22:113-118.
    • (2003) Endocrine , vol.22 , pp. 113-118
    • Armanini, D.1    Vecchio, F.2    Basso, A.3
  • 201
    • 21644471827 scopus 로고    scopus 로고
    • Studies on homocysteine and dehydroepiandrosterone sulphate plasma levels in Alzheimer's disease patients and in Parkinson's disease patients
    • Genedani S, Rasio G, Cortelli P, et al. Studies on homocysteine and dehydroepiandrosterone sulphate plasma levels in Alzheimer's disease patients and in Parkinson's disease patients. Neurotox Res 2004;6:327-332.
    • (2004) Neurotox Res , vol.6 , pp. 327-332
    • Genedani, S.1    Rasio, G.2    Cortelli, P.3
  • 202
    • 0029871868 scopus 로고    scopus 로고
    • Serum dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEA-S) in Alzheimer's disease and in cerebrovascular dementia
    • Yanase T, Fukahori M, Taniguchi S, et al. Serum dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEA-S) in Alzheimer's disease and in cerebrovascular dementia. Endocr J 1996;43:119-123.
    • (1996) Endocr J , vol.43 , pp. 119-123
    • Yanase, T.1    Fukahori, M.2    Taniguchi, S.3
  • 203
    • 0033959473 scopus 로고    scopus 로고
    • Dehydroepiandrosterone sulfate and psychiatric measures in a frail, elderly residential care population
    • Morrison MF, Redei E, Ten Have T, et al. Dehydroepiandrosterone sulfate and psychiatric measures in a frail, elderly residential care population. Biol Psychiatry 2000;47:144-1450.
    • (2000) Biol Psychiatry , vol.47 , pp. 144-1450
    • Morrison, M.F.1    Redei, E.2    Ten Have, T.3
  • 204
    • 84892022522 scopus 로고    scopus 로고
    • CANTAB, Cambridge Automated Neuropsychological Test Battery. http://www.cantab.com/cantab/site/home.acds).
  • 206
    • 0017221890 scopus 로고
    • Cerebral blood flow patterns studied by rheoencephalography in schizophrenia
    • Jacquy J, Wilmotte J, et al. Cerebral blood flow patterns studied by rheoencephalography in schizophrenia. Neuropsychobiology 1976;2:94-103.
    • (1976) Neuropsychobiology , vol.2 , pp. 94-103
    • Jacquy, J.1    Wilmotte, J.2
  • 207
    • 0030606008 scopus 로고    scopus 로고
    • Prefrontal function in schizophrenia: Confounds and controversies
    • Weinberger DR, Berman KF. Prefrontal function in schizophrenia: confounds and controversies. Philos Trans R Soc Lond B Biol Sci 1996;351:1495-1503.
    • (1996) Philos Trans R Soc Lond B Biol Sci , vol.351 , pp. 1495-1503
    • Weinberger, D.R.1    Berman, K.F.2
  • 208
    • 4644291261 scopus 로고    scopus 로고
    • Hypofrontality in schizophrenia: A meta-analysis of functional imaging studies
    • Hill K, Mann L, et al. Hypofrontality in schizophrenia: a meta-analysis of functional imaging studies. Acta Psychiatr Scand 2004;110:243-256.
    • (2004) Acta Psychiatr Scand , vol.110 , pp. 243-256
    • Hill, K.1    Mann, L.2
  • 209
    • 0025017081 scopus 로고
    • Hypofrontality and cognitive impairment in schizophrenia: Dynamic single-photon tomography and neuropsychological assessment of schizophrenic brain function
    • Paulman RG, Devous MD, Sr, et al. Hypofrontality and cognitive impairment in schizophrenia: dynamic single-photon tomography and neuropsychological assessment of schizophrenic brain function. Biol Psychiatry 1990;27:377-399.
    • (1990) Biol Psychiatry , vol.27 , pp. 377-399
    • Paulman, R.G.1    Devous Sr., M.D.2
  • 210
    • 0037441795 scopus 로고    scopus 로고
    • Quantification of frontal and temporal lobe brain-imaging findings in schizophrenia: A meta-analysis
    • Davidson LL, Heinrichs RW. Quantification of frontal and temporal lobe brain-imaging findings in schizophrenia: a meta-analysis. Psychiatry Res 2003;122:69-87.
    • (2003) Psychiatry Res , vol.122 , pp. 69-87
    • Davidson, L.L.1    Heinrichs, R.W.2
  • 211
    • 0035024624 scopus 로고    scopus 로고
    • Hypofrontality in neuroleptic-naive schizophrenic patients during the Wisconsin Card Sorting Test - A fMRI study
    • Riehemann S, Volz HP, et al. Hypofrontality in neuroleptic-naive schizophrenic patients during the Wisconsin Card Sorting Test - a fMRI study. Eur Arch Psychiatry Clin Neurosci 2001;251:66-71.
    • (2001) Eur Arch Psychiatry Clin Neurosci , vol.251 , pp. 66-71
    • Riehemann, S.1    Volz, H.P.2
  • 212
    • 28844495657 scopus 로고    scopus 로고
    • Regional cerebral blood flow SPECT study, at rest and during Wisconsin Card Sorting Test (WCST) performance, in schizophrenia naive patients or treated with atypical neuroleptics
    • Moreno-Iniguez M, Ortuno F, et al. Regional cerebral blood flow SPECT study, at rest and during Wisconsin Card Sorting Test (WCST) performance, in schizophrenia naive patients or treated with atypical neuroleptics. Actas Esp Psiquiatr 2005;33:343-351.
    • (2005) Actas Esp Psiquiatr , vol.33 , pp. 343-351
    • Moreno-Iniguez, M.1    Ortuno, F.2
  • 213
    • 33646778138 scopus 로고    scopus 로고
    • Cortical blood flow during rest and Wisconsin Card Sorting Test performance in schizophrenia
    • Ortuno F, Moreno-Iniguez M, et al. Cortical blood flow during rest and Wisconsin Card Sorting Test performance in schizophrenia. Wien Med Wochenschr 2006;156:179-184.
    • (2006) Wien Med Wochenschr , vol.156 , pp. 179-184
    • Ortuno, F.1    Moreno-Iniguez, M.2
  • 214
    • 0034713330 scopus 로고    scopus 로고
    • Hypofrontality in unmedicated schizophrenia patients studied with PET during performance of a serial verbal learning task
    • Hazlett EA, Buchsbaum MS, et al. Hypofrontality in unmedicated schizophrenia patients studied with PET during performance of a serial verbal learning task. Schizophr Res 2000;43:33-46.
    • (2000) Schizophr Res , vol.43 , pp. 33-46
    • Hazlett, E.A.1    Buchsbaum, M.S.2
  • 215
    • 0029646110 scopus 로고
    • Combined dexamethasone/corticotropinreleasing hormone test in patients with schizophrenia and in normal controls. II
    • Lammers CH, Garcia-Borreguero D, Schmider J, et al. Combined dexamethasone/corticotropinreleasing hormone test in patients with schizophrenia and in normal controls. II. Biol Psychiatry 1995;38:803-807.
    • (1995) Biol Psychiatry , vol.38 , pp. 803-807
    • Lammers, C.H.1    Garcia-Borreguero, D.2    Schmider, J.3
  • 216
    • 35848966767 scopus 로고    scopus 로고
    • Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: Candidate mechanism for superior efficacy?
    • Marx CE, Shampine LJ, et al. Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: candidate mechanism for superior efficacy? Pharmacol Biochem Behav 2006;84:598-608.
    • (2006) Pharmacol Biochem Behav , vol.84 , pp. 598-608
    • Marx, C.E.1    Shampine, L.J.2
  • 217
    • 34447639040 scopus 로고    scopus 로고
    • Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: Implications for therapeutic actions
    • Marx CE, Shampine LJ, et al. Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions. Pharmacol Biochem Behav 2006;84:609-617.
    • (2006) Pharmacol Biochem Behav , vol.84 , pp. 609-617
    • Marx, C.E.1    Shampine, L.J.2
  • 218
    • 0023023338 scopus 로고
    • Effect of chronic hyperprolactinemia induced by sulpiride on plasma dehydroepiandrosterone (DHA) in normal men
    • Oseko F, Morikawa K, Nakano A, et al. Effect of chronic hyperprolactinemia induced by sulpiride on plasma dehydroepiandrosterone (DHA) in normal men. Andrologia 1986;18:523-528.
    • (1986) Andrologia , vol.18 , pp. 523-528
    • Oseko, F.1    Morikawa, K.2    Nakano, A.3
  • 219
    • 27144435117 scopus 로고    scopus 로고
    • Cortisol/dehydroepiandrosterone ratio and responses to antipsychotic treatment in schizophrenia
    • Ritsner M, Gibel A, Maayan R, et al. Cortisol/dehydroepiandrosterone ratio and responses to antipsychotic treatment in schizophrenia. Neuropsychopharmacology 2005;30:1913-1922.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1913-1922
    • Ritsner, M.1    Gibel, A.2    Maayan, R.3
  • 220
    • 0031892223 scopus 로고    scopus 로고
    • Platelet 5-HT and plasma cortisol concentrations after dexamethasone suppression test in patients with different time course of schizophrenia
    • Jakovljevic M, Muck-Seler D, Pivac N, Crncevic Z. Platelet 5-HT and plasma cortisol concentrations after dexamethasone suppression test in patients with different time course of schizophrenia. Neuropsychobiology 1998;37:142-145.
    • (1998) Neuropsychobiology , vol.37 , pp. 142-145
    • Jakovljevic, M.1    Muck-Seler, D.2    Pivac, N.3    Crncevic, Z.4
  • 221
    • 0031255540 scopus 로고    scopus 로고
    • Schizophrenia: A neural diathesis-stress model
    • Walker EF, Diforio D. Schizophrenia: a neural diathesis-stress model. Psychology Review 1997;104:667-685.
    • (1997) Psychology Review , vol.104 , pp. 667-685
    • Walker, E.F.1    Diforio, D.2
  • 222
    • 0032781753 scopus 로고    scopus 로고
    • Immunological properties of dehydroepiandrosterone, its conjugates, and metabolites
    • Bradlow HL, Murphy J, Byrne JJ. Immunological properties of dehydroepiandrosterone, its conjugates, and metabolites. Ann NY Acad Sci 1999;876:91-101.
    • (1999) Ann NY Acad Sci , vol.876 , pp. 91-101
    • Bradlow, H.L.1    Murphy, J.2    Byrne, J.J.3
  • 223
    • 0033198566 scopus 로고    scopus 로고
    • Neuroactive steroids: Mechanisms of action and neuropsychopharmacological perspectives
    • Rupprecht R, Holsboer F. Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives. Trends Neurosci 1999;22:410-416.
    • (1999) Trends Neurosci , vol.22 , pp. 410-416
    • Rupprecht, R.1    Holsboer, F.2
  • 224
  • 225
    • 33745650483 scopus 로고    scopus 로고
    • Neuroactive steroids are altered in schizophrenia and bipolar disorder: Relevance to pathophysiology and therapeutics
    • Marx CE, Stevens RD, et al. Neuroactive steroids are altered in schizophrenia and bipolar disorder: relevance to pathophysiology and therapeutics. Neuropsychopharmacology 2006;31:1249-1263.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1249-1263
    • Marx, C.E.1    Stevens, R.D.2
  • 226
    • 0037177552 scopus 로고    scopus 로고
    • Schizophrenia: Diverse approaches to a complex disease
    • Sawa A, Snyder SH. Schizophrenia: diverse approaches to a complex disease. Science 2002;296:692-695.
    • (2002) Science , vol.296 , pp. 692-695
    • Sawa, A.1    Snyder, S.H.2
  • 228
    • 34249944258 scopus 로고    scopus 로고
    • Steroid pregnenolone sulfate enhances NMDAreceptorindependent long-term potentiation at hippocampal CA1 synapses: Role for L-type calcium channels and sigma-receptors
    • epub ahead of print
    • Sabeti J, Nelson TE, Purdy RH, Gruol DL. Steroid pregnenolone sulfate enhances NMDAreceptorindependent long-term potentiation at hippocampal CA1 synapses: role for L-type calcium channels and sigma-receptors. Hippocampus 2007 [epub ahead of print].
    • (2007) Hippocampus
    • Sabeti, J.1    Nelson, T.E.2    Purdy, R.H.3    Gruol, D.L.4
  • 229
    • 0032756551 scopus 로고    scopus 로고
    • Neuroactive neurosteroids as endogenous effectors for the sigma1 (sigma1) receptor: Pharmacological evidence and therapeutic opportunities
    • Maurice T, Phan VL, Urani A, et al. Neuroactive neurosteroids as endogenous effectors for the sigma1 (sigma1) receptor: pharmacological evidence and therapeutic opportunities. Jpn J Pharmacol 1999;81:125-155.
    • (1999) Jpn J Pharmacol , vol.81 , pp. 125-155
    • Maurice, T.1    Phan, V.L.2    Urani, A.3
  • 230
    • 0035660075 scopus 로고    scopus 로고
    • The interaction between neuroactive steroids and the sigma1 receptor function: Behavioral consequences and therapeutic opportunities
    • Maurice T, Urani A, Phan VL, Romieu P. The interaction between neuroactive steroids and the sigma1 receptor function: behavioral consequences and therapeutic opportunities. Brain Res Brain Res Rev 2001;37:116-132.
    • (2001) Brain Res Brain Res Rev , vol.37 , pp. 116-132
    • Maurice, T.1    Urani, A.2    Phan, V.L.3    Romieu, P.4
  • 231
    • 0030899744 scopus 로고    scopus 로고
    • Protective effect of dehydroepiandrosterone against copper-induced lipid peroxidation in the rat
    • Boccuzzi G, Aragno M, Seccia M, et al. Protective effect of dehydroepiandrosterone against copper-induced lipid peroxidation in the rat. Free Radic Biol Med 1997;22:1289-1294.
    • (1997) Free Radic Biol Med , vol.22 , pp. 1289-1294
    • Boccuzzi, G.1    Aragno, M.2    Seccia, M.3
  • 232
    • 0030667861 scopus 로고    scopus 로고
    • Dehydroepiandrosterone administration prevents the oxidative damage induced by acute hyperglycemia in rats
    • Aragno M, Brignardello E, Tamagno E, et al. Dehydroepiandrosterone administration prevents the oxidative damage induced by acute hyperglycemia in rats. J Endocrinol 1997;155:233-240.
    • (1997) J Endocrinol , vol.155 , pp. 233-240
    • Aragno, M.1    Brignardello, E.2    Tamagno, E.3
  • 233
    • 0032539540 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity
    • Kimonides VG, Khatibi NH, et al. Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity. Proc Natl Acad Sci USA 1998;95:1852-1857.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1852-1857
    • Kimonides, V.G.1    Khatibi, N.H.2
  • 234
    • 0032747654 scopus 로고    scopus 로고
    • Dehydroepiandrosterone protects hippocampal neurons against neurotoxin-induced cell death: Mechanism of action
    • Cardounel A, Regelson W, et al. Dehydroepiandrosterone protects hippocampal neurons against neurotoxin-induced cell death: mechanism of action. Proc Soc Exp Biol Med 1999;222:145-149.
    • (1999) Proc Soc Exp Biol Med , vol.222 , pp. 145-149
    • Cardounel, A.1    Regelson, W.2
  • 235
    • 0033586349 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage
    • Bastianetto S, Ramassamy C, et al. Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage. Brain Res Mol Brain Res 1999;66:35-41.
    • (1999) Brain Res Mol Brain Res , vol.66 , pp. 35-41
    • Bastianetto, S.1    Ramassamy, C.2
  • 236
    • 2542553473 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins
    • Charalampopoulos I, Tsatsanis C, et al. Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins. Proc Natl Acad Sci USA 2004;101:8209-8214.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8209-8214
    • Charalampopoulos, I.1    Tsatsanis, C.2
  • 237
    • 0029552972 scopus 로고
    • Neuronal actions of dehydroepiandrosterone. Possible roles in brain development, aging, memory, and affect
    • Majewska MD. Neuronal actions of dehydroepiandrosterone. Possible roles in brain development, aging, memory, and affect. Ann NY Acad Sci 1995;774:111-120.
    • (1995) Ann NY Acad Sci , vol.774 , pp. 111-120
    • Majewska, M.D.1
  • 238
    • 0037146704 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and alpha-estradiol limit the functional alterations of rat brain mitochondria submitted to different experimental stresses
    • Morin C, Zini R, Simon N, Tillement JP. Dehydroepiandrosterone and alpha-estradiol limit the functional alterations of rat brain mitochondria submitted to different experimental stresses. Neuroscience 2002;115:415-424.
    • (2002) Neuroscience , vol.115 , pp. 415-424
    • Morin, C.1    Zini, R.2    Simon, N.3    Tillement, J.P.4
  • 239
    • 1542297733 scopus 로고    scopus 로고
    • Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex
    • Suzuki M, Wright LS, Marwah P, et al. Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex. Proc Natl Acad Sci USA. 2004;101:3202-3207.
    • (2004) Proc Natl Acad Sci USA. , vol.101 , pp. 3202-3207
    • Suzuki, M.1    Wright, L.S.2    Marwah, P.3
  • 240
    • 2142639393 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes
    • Takahashi H, Nakajima A, et al. Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes. J Steroid Biochem Mol Biol 2004;88:261-264.
    • (2004) J Steroid Biochem Mol Biol , vol.88 , pp. 261-264
    • Takahashi, H.1    Nakajima, A.2
  • 241
    • 4644246927 scopus 로고    scopus 로고
    • Beta-estradiol, dehydroepiandrosterone, and dehydroepiandrosterone sulfate protect against N-methyl-D-aspartate-induced neurotoxicity in rat hippocampal neurons by different mechanisms
    • Kurata K, Takebayashi M, et al. Beta-estradiol, dehydroepiandrosterone, and dehydroepiandrosterone sulfate protect against N-methyl-D-aspartate-induced neurotoxicity in rat hippocampal neurons by different mechanisms. J Pharmacol Exp Ther 2004;311:237-245.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 237-245
    • Kurata, K.1    Takebayashi, M.2


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