Cognitive and affective disorders in the elderly: A neuroendocrine study

Archives of Gerontology and Geriatrics

Volumn 38, Issue SUPPL., 2004, Pages 171-182

  Ferrari, E ^a   Mirani, M ^a   Barili, L ^a   Falvo, F ^a   Solerte, S B ^a   Cravello, L ^a   Pini, L ^a   Magri, F ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

Brain aging; Circadian rhythm of serum cortisol; De hydroepiandrosterone (DHEAS); Hypothalamo pituitary adrenal (HPA) axis; Physiological aging

Indexed keywords

HYDROCORTISONE; PRASTERONE; PRASTERONE SULFATE;

AGED; AGING; ARTICLE; CIRCADIAN RHYTHM; COGNITIVE DEFECT; COMPARATIVE STUDY; CONTROLLED STUDY; DEPRESSION; HORMONE BLOOD LEVEL; HUMAN; HYDROCORTISONE BLOOD LEVEL; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MOOD DISORDER; NEUROENDOCRINOLOGY; PRIORITY JOURNAL; SENILE DEMENTIA; BLOOD; COMORBIDITY; FEMALE; FLUOROIMMUNOASSAY; HOSPITALIZATION; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; METABOLISM; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGED; AGED, 80 AND OVER; AGING; CIRCADIAN RHYTHM; COGNITION DISORDERS; COMORBIDITY; DEHYDROEPIANDROSTERONE; DEPRESSIVE DISORDER, MAJOR; FEMALE; FLUOROIMMUNOASSAY; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; NEUROPSYCHOLOGICAL TESTS; PITUITARY-ADRENAL SYSTEM; SEVERITY OF ILLNESS INDEX;

EID: 3042636200     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archger.2004.04.024     Document Type: Article

References (27)

1. APA (American Psychiatric Association) (1 994): Diagnostic and Statistical Manual of Mental Disorders, 4th ed. APA Press, Washington, D.C.
2. Belanoff, J.K., Kelehzan, M., Sund, B., Fleming Ficek, S.K. and Schatzberg, A.F. (2001): Cortisol activity and cognitive changes in psychotic major depression. Am. J. Psychiatry, 158, 1612-1616.
3. Bingham, C., Arbogast, B., Guillaume, G.C., Lee, J.K. and Halberg, F. (1982): Inferential statistical methods for estimating and comparing cosinor parameters. Chronobiol., 9, 387-439.
4. Deuschle, M., Schweiger, U., Weber, B., Gotthardt, U., Korner, A., Schmider, J., Standhardt, H., Lammers, C.H. and Heuser, I. (1997): Diurnal activity and pulsatility of the hypothalamus-pituitary-adrenal system in male depressed patients and healthy controls. J. Clin. Endocrinol. Metab., 82, 234-238.
5. Ferrari, E., Cravello, L., Muzzoni, B., Casarotti, D., Paltro, M., Solerte, S.B., Fioravanti, M., Cuzzoni, G., Pontiggia, B. and Magri, F. (2001): Age-related changes of the hypotha-lamic-pituitary-adrenal axis: pathophysiological correlates. Eur. J. Endocrinol., 144, 319-329.
6. Fitten, L.J., Morley, J.E., Gross, P.L., Petry, S.D. and Cole, K.D. (1989): Depression. J. Am. Geriatr. Soc., 37, 459 -742.
7. Folstein, M.F., Folstein, S.E. and McHugh, P.R. (1975): Mini-Mental State. A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res., 12, 189-198.
8. Girling, D.M., Barkley, C., Paykel, E.S., Gehlhaar, E., Brayne, C., Gill, C., Mathewson, D. and Huppert, F.A. (1995): The prevalence of depression in a cohort of very elderly. J. Affect. Dis., 34, 319-329.
9. Goodyer, I.M., Herbert, J., Altham, P.M., Pearson, J., Secher, S.M. and Shiers, H.M. (1996): Adrenal secretion during major depression in 8- to 16-year-olds, I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation. Psychol. Med., 26, 245-256.
10. Hachinski, V.C., Lassen, N.A. and Marshall, J. (1974): Multinfarct dementia: a cause of mental deterioration in the elderly. Lancet, 2, 207-210.
11. Halberg, F. (1968): Chronobiology. Am. Rev. Physiol., 31, 378-382.
12. Heuser, I., Deuschle, M., Luppa, P., Schweiger, U., Standhardt, H. and Weber, B. (1998): Increased diurnal plasma concentrations of dehydroepiandrosterone in depressed patients. J. Clin. Endocrinol. Metab., 83, 3130-3133.
13. Heuser, I., Yassouridis, A. and Holsboer, F. (1994): The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders. J. Psychiatr. Res., 28, 341-356.
14. Hughes, C.P., Berg, L. and Danziger, W.L. (1982): A new clinical scale for the staging of dementia. Br. J. Psychiatry, 140, 566-572.
15. Lucassen, P.J., Müller, M.B., Holsboer, F., Bauer, J., Holtrop, A., Wouda, J., Hoogendijk, W.J.G., De Kloet, E.R. and Swaab, D.F. (2001): Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure. Am. J. Pathol., 158, 453-468.
16. Lupien, S.J. and McEwen, B.S. (1997): The acute effects of corticosteroids on cognitition: integration of animal and human model studies. Brain Res. Rev., 24, 1-27.
17. Magri, F., Terenzi, F., Ricciardi, T., Fioravanti, M., Solerte, S.B., Stabile, M., Balza, G., Gandini C., Villa, M. and Ferrari, E. (2000): Association between changes in adrenal secretion and cerebral morphometric correlates in normal aging. Dement. Geriatr. Cogn. Disord., 11, 90-99.
18. McCrea, D., Arnold, E., Marchevsky, D. and Kaufman, B.M. (1994): The prevalence of depression in geriatric medical outpatients. Age Ageing, 23, 465-467.
19. McEwen, B.S. (2001): Plasticity of hippocampus: adaptation to chronic stress and allostatic load. Ann. N.Y. Acad. Sci., 933, 265-277.
20. McKhann, G., Drachman, D., Folstein, M., Katzmann, R., Price, D. and Stadlan, E.M. (1984): Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA workgroup under the auspices of Department of Healthy and Human Services Task Force on Alzheimer's disease. Neurology, 34, 939-944.
21. Michael, A., Jenaway, A., Paykel, E.S. and Herbert, I. (2000): Altered salivary dehydro-epiandrosterone levels in major depression in adults. J. Biol. Psychiatry, 48, 989-995.
22. Ribakowski, J.K. and Twardowska, K. (1999): The dexamethasone/ corticotropin-releasing hormone test in depression in bipolar and unipolar affective illness. J. Psychiatr. Res., 33, 363-370.
23. Schule, C., Baghai, T., Zwanzger, P., Minov, C., Padberg, F. and Rupprecht, R. (2001): Sleep deprivation and hypothalamic-pituitary-adrenal (HPA) axis activity in depressed patients. J. Psychiatr. Res., 35, 239-247.
24. Sheikh, J.I. and Yesavage, J.A. (1982): A knowledge assessment test for geriatric psychiatry. Hosp. Community Psychiatry, 36, 1160-1166.
25. Tollefson, G.D. (I 990): Differentiating anxiety and depression. Psychiatr. Med., 8, 27-39.
26. Wehr, T.A. and Wirz-Jusctice, A. (1982): Circadian rhythm mechanisms in affective illness and in antidepressant drug action. Pharmacopsychiatria 15, 31-39.
27. Zwanzger, P., Baghai, T.C., Padberg, F., Ella, R., Minov, C., Mikhaiel, P., Schule, C., Thoma, H. and Rupprecht, R. (2003): The combined dexamethasone-CRH test before and after repetitive transcranial magnetic stimulation (rTMS) in major depression. Psychoneuroendocrinology, 28, 376-385.