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Volumn 9, Issue 14, 2009, Pages 1240-1260

Inflammation as a therapeutic target in acute ischemic stroke treatment

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; ADENOSINE TRIPHOSPHATE; ALPHAMBETA2 INTEGRIN; BATIMASTAT; BETA2 INTEGRIN; C REACTIVE PROTEIN; CD36 ANTIGEN; CD39 ANTIGEN; CRX 102; CYTOKINE; DIPYRIDAMOLE; DIZOCILPINE; EP 80317; ETANERCEPT; GELATINASE INHIBITOR; HEXARELIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INFLIXIMAB; INTERCELLULAR ADHESION MOLECULE 1 ANTIBODY; INTERLEUKIN 1 ANTIBODY; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; KB R 7785; PLACEBO; PREDNISOLONE; PURINERGIC P2X7 RECEPTOR; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; ROSUVASTATIN; SEMAPIMOD; TACROLIMUS; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 74249120803     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802609789869619     Document Type: Review
Times cited : (109)

References (164)
  • 1
    • 33847644971 scopus 로고    scopus 로고
    • The inflammatory response in stroke
    • Wang, Q.; Tang, X.N.; Yenari, M.A. The inflammatory response in stroke. J. Neuroimmunol. 2006, 184, 53-68.
    • (2006) J. Neuroimmunol , vol.184 , pp. 53-68
    • Wang, Q.1    Tang, X.N.2    Yenari, M.A.3
  • 4
    • 62249217322 scopus 로고    scopus 로고
    • Ischemic stroke intervention requires mixed cellular protection of the penumbra
    • Barone, F.C. Ischemic stroke intervention requires mixed cellular protection of the penumbra. Curr. Opin. Invest. Drugs 2009, (10), 220-223.
    • (2009) Curr. Opin. Invest. Drugs , vol.10 , pp. 220-223
    • Barone, F.C.1
  • 5
    • 0026496903 scopus 로고    scopus 로고
    • Beamer,. N.B.; Coull, B.M.; Clark, W.M.; Hazel, J.S.; Silberger, Dereski, M.O.; Chopp, M.; Knight, R.A.; Garcia, H. Focal cerebral ischemia in the rat, temporal profile of neutrophil responses. Neurosci. Res. Commun. 1992, 11, 179-186
    • Beamer,. N.B.; Coull, B.M.; Clark, W.M.; Hazel, J.S.; Silberger, Dereski, M.O.; Chopp, M.; Knight, R.A.; Garcia, H. Focal cerebral ischemia in the rat, temporal profile of neutrophil responses. Neurosci. Res. Commun. 1992, 11, 179-186
  • 6
    • 0141819133 scopus 로고    scopus 로고
    • C-reactive protein predicts further ischemic events in first-ever transient ischemic attack or stroke patients with intracranial large-artery occlusive disease
    • Arenillas, J.F.; Alvarez-Sabín, J.; Molina, C.A.; Chacón, P.; Montaner, J.; Rovira, A.; Ibarra, B.; Quintana, M. C-reactive protein predicts further ischemic events in first-ever transient ischemic attack or stroke patients with intracranial large-artery occlusive disease. Stroke 2003, 34(10), 2463-8.
    • (2003) Stroke , vol.34 , Issue.10 , pp. 2463-2468
    • Arenillas, J.F.1    Alvarez-Sabín, J.2    Molina, C.A.3    Chacón, P.4    Montaner, J.5    Rovira, A.6    Ibarra, B.7    Quintana, M.8
  • 7
  • 8
    • 65549107812 scopus 로고    scopus 로고
    • Metabolic syndrome and C-reactive protein in stroke prediction: A prospective study in Taiwan
    • Chen, P.C.; Chien, K.L.; Hsu, H.C.; Su, T.C.; Sung, F.C.; Lee, Y.T. Metabolic syndrome and C-reactive protein in stroke prediction: a prospective study in Taiwan. Metabolism 2009, 58(6), 772-8.
    • (2009) Metabolism , vol.58 , Issue.6 , pp. 772-778
    • Chen, P.C.1    Chien, K.L.2    Hsu, H.C.3    Su, T.C.4    Sung, F.C.5    Lee, Y.T.6
  • 9
    • 18244409093 scopus 로고    scopus 로고
    • C-reactive protein inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by activating p38 kinase and NAD(P)H oxidase
    • Qamirani, E.; Ren, Y.; Kuo, L.; Hein, T.W. C-reactive protein inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by activating p38 kinase and NAD(P)H oxidase. Arterioscler. Thromb. Vasc. Biol. 2005, 25(5), 995-1001.
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , Issue.5 , pp. 995-1001
    • Qamirani, E.1    Ren, Y.2    Kuo, L.3    Hein, T.W.4
  • 11
    • 58749106299 scopus 로고    scopus 로고
    • Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke
    • Welsh, P.; Barber, M.; Langhorne, P.; Rumley, A.; Lowe, G.D.; Stott, D.J. Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke. Cerebrovasc. Dis. 2009, 27(3), 247-53.
    • (2009) Cerebrovasc. Dis , vol.27 , Issue.3 , pp. 247-253
    • Welsh, P.1    Barber, M.2    Langhorne, P.3    Rumley, A.4    Lowe, G.D.5    Stott, D.J.6
  • 12
    • 62449089772 scopus 로고    scopus 로고
    • Elevated C-reactive protein and long-term mortality after ischaemic stroke, relationship with markers of endothelial cell and platelet activation
    • Shantikumar, S.; Grant, P.J.; Catto, A.J.; Bamford, J.M.; Carter, A.M. Elevated C-reactive protein and long-term mortality after ischaemic stroke, relationship with markers of endothelial cell and platelet activation. Stroke 2009, 40(3), 977-9.
    • (2009) Stroke , vol.40 , Issue.3 , pp. 977-979
    • Shantikumar, S.1    Grant, P.J.2    Catto, A.J.3    Bamford, J.M.4    Carter, A.M.5
  • 13
    • 58149162973 scopus 로고    scopus 로고
    • The effect of C-reactive protein on functional outcome in ischemic stroke patients
    • Ryu, S.R.; Choi, I.S.; Bian, R.X.; Kim, J.H.; Han, J.Y.; Lee, S.G. The effect of C-reactive protein on functional outcome in ischemic stroke patients. Int. J. Neurosci. 2009, 119(3), 336.
    • (2009) Int. J. Neurosci , vol.119 , Issue.3 , pp. 336
    • Ryu, S.R.1    Choi, I.S.2    Bian, R.X.3    Kim, J.H.4    Han, J.Y.5    Lee, S.G.6
  • 14
    • 65649149373 scopus 로고    scopus 로고
    • Admission C-reactive protein after acute ischemic stroke is associated with stroke severity and mortality, the 'Bergen stroke study'
    • Idicula, T.T.; Brogger, J.; Naess, H.; Waje-Andreassen, U.; Thomassen, L. Admission C-reactive protein after acute ischemic stroke is associated with stroke severity and mortality, the 'Bergen stroke study'. BMC Neurol. 2009, 9, 18.
    • (2009) BMC Neurol , vol.9 , pp. 18
    • Idicula, T.T.1    Brogger, J.2    Naess, H.3    Waje-Andreassen, U.4    Thomassen, L.5
  • 15
    • 67649908743 scopus 로고    scopus 로고
    • Short-term effects of an anti-inflammatory treatment on clinical parameters and serum levels of C-reactive protein and proinflammatory cytokines in subjects with periodontitis
    • Renvert, S.; Lindahl, C.; Roos-Jansåker, A.M.; Lessem, J. Short-term effects of an anti-inflammatory treatment on clinical parameters and serum levels of C-reactive protein and proinflammatory cytokines in subjects with periodontitis. J. Periodontol. 2009, 80(6), 892-900.
    • (2009) J. Periodontol , vol.80 , Issue.6 , pp. 892-900
    • Renvert, S.1    Lindahl, C.2    Roos-Jansåker, A.M.3    Lessem, J.4
  • 16
    • 0035806626 scopus 로고    scopus 로고
    • PRINCE Investigators Effect of statin therapy on C-reactive protein levels, the pravastatin inflammation/CRP evaluation (PRINCE), a randomized trial and cohort study
    • Albert, M.A.; Danielson, E.; Rifai, N.; Ridker, P.M. PRINCE Investigators Effect of statin therapy on C-reactive protein levels, the pravastatin inflammation/CRP evaluation (PRINCE), a randomized trial and cohort study. JAMA 2001, 286(1), 64-70.
    • (2001) JAMA , vol.286 , Issue.1 , pp. 64-70
    • Albert, M.A.1    Danielson, E.2    Rifai, N.3    Ridker, P.M.4
  • 17
    • 72949099408 scopus 로고    scopus 로고
    • Effect of atorvastatin on circulating hsCRP concentrations: A sub-study of the Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (ACTFAST) study on behalf of the ACTFAST investigators
    • Epub ahead of print
    • Gensini, G.F.; Gori, A.M.; Dilaghi, B.; Rostagno, C.; Gaw, A.; Blanco-Colio, L.M.; de Teresa, E.; Egido, J.; Farsang, C.; Leiter, L.A.; Martineau, P.; Nozza, A.; Langer, A. Effect of atorvastatin on circulating hsCRP concentrations: A sub-study of the Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (ACTFAST) study on behalf of the ACTFAST investigators. Int. J. Cardiol. 2009 [Epub ahead of print].
    • (2009) Int. J. Cardiol
    • Gensini, G.F.1    Gori, A.M.2    Dilaghi, B.3    Rostagno, C.4    Gaw, A.5    Blanco-Colio, L.M.6    de Teresa, E.7    Egido, J.8    Farsang, C.9    Leiter, L.A.10    Martineau, P.11    Nozza, A.12    Langer, A.13
  • 19
    • 0034833822 scopus 로고    scopus 로고
    • 36, a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism
    • Febbraio, M.; Hajjar, D.P.; Silverstein, R.L. CD36, a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism. J. Clin. Invest. 2001, 108, 785-791.
    • (2001) J. Clin. Invest , vol.108 , pp. 785-791
    • Febbraio, M.1    Hajjar, D.P.2    Silverstein, R.L.C.3
  • 20
    • 33947495568 scopus 로고    scopus 로고
    • A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36
    • Cho, S.; Szeto, H.H.; Kim, E.; Kim, H.; Tolhurst, A.T.; Pinto, J.T. A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36. J. Biol. Chem. 2007, 282, 4634-4642.
    • (2007) J. Biol. Chem , vol.282 , pp. 4634-4642
    • Cho, S.1    Szeto, H.H.2    Kim, E.3    Kim, H.4    Tolhurst, A.T.5    Pinto, J.T.6
  • 21
    • 14944379101 scopus 로고    scopus 로고
    • The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia
    • Cho, S.; Park, E.M.; Febbraio, M.; Anrather, J.; Park, L.; Racchumi, G.; Silverstein, R.L.; Iadecola, C. The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia. J. Neurosci. 2005, 25, 2504-2512.
    • (2005) J. Neurosci , vol.25 , pp. 2504-2512
    • Cho, S.1    Park, E.M.2    Febbraio, M.3    Anrather, J.4    Park, L.5    Racchumi, G.6    Silverstein, R.L.7    Iadecola, C.8
  • 24
  • 27
    • 4544363024 scopus 로고    scopus 로고
    • Identification of the growth hormone-releasing peptide binding site in CD36, a photoaffinity cross-linking study
    • Demers, A.; McNicoll, N.; Febbraio, M.; Servant, M.; Marleau, S.; Silverstein, R.; Ong, H. Identification of the growth hormone-releasing peptide binding site in CD36, a photoaffinity cross-linking study. Biochem. J. 2004, 382, 417-424.
    • (2004) Biochem. J , vol.382 , pp. 417-424
    • Demers, A.1    McNicoll, N.2    Febbraio, M.3    Servant, M.4    Marleau, S.5    Silverstein, R.6    Ong, H.7
  • 28
    • 14944379101 scopus 로고    scopus 로고
    • The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia
    • Cho, S.; Park, E.M.; Febbraio, M.; Anrather, J.; Park, L.; Racchumi, G.; Silverstein, R.L.; Iadecola, C. The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia. J. Neurosci. 2005, 25(10), 2504-12.
    • (2005) J. Neurosci , vol.25 , Issue.10 , pp. 2504-2512
    • Cho, S.1    Park, E.M.2    Febbraio, M.3    Anrather, J.4    Park, L.5    Racchumi, G.6    Silverstein, R.L.7    Iadecola, C.8
  • 29
    • 0026530776 scopus 로고
    • Induction of interleukin-lb mRNA in rat brain after transient forebrain ischaemia
    • Minami, M.; Kuraishi, Y.; Yabuuchi, K.; Yamazaki, K.; Satoh, M. Induction of interleukin-lb mRNA in rat brain after transient forebrain ischaemia. J. Neurochem. 1992, 58, 390-392.
    • (1992) J. Neurochem , vol.58 , pp. 390-392
    • Minami, M.1    Kuraishi, Y.2    Yabuuchi, K.3    Yamazaki, K.4    Satoh, M.5
  • 30
    • 0028176793 scopus 로고
    • Induction of interleukin-1 beta mRNA after focal cerebral ischaemia in the rat
    • Buttini, H.; Sauter, M.; Boddeke, A. Induction of interleukin-1 beta mRNA after focal cerebral ischaemia in the rat. Mol. Brain Res. 1994, 23(1-2), 126-34.
    • (1994) Mol. Brain Res , vol.23 , Issue.1-2 , pp. 126-134
    • Buttini, H.1    Sauter, M.2    Boddeke, A.3
  • 33
    • 0026650384 scopus 로고
    • Upregulation of intercellular adhesion molecules-l (ICAM-1) expression in primary cultures of human microvessel endothelial cells by cytokines and lipopolysaccharide
    • Liu, T.; Clark, R.K.; McConnell, P.C.; Young, P.R.; White, R.F.; Barone, F.C.; Wong, D.; Dorovini-Zis, K. Upregulation of intercellular adhesion molecules-l (ICAM-1) expression in primary cultures of human microvessel endothelial cells by cytokines and lipopolysaccharide. J. Neuroimmunol. 1992, 39, 1l-21.
    • (1992) J. Neuroimmunol , vol.39
    • Liu, T.1    Clark, R.K.2    McConnell, P.C.3    Young, P.R.4    White, R.F.5    Barone, F.C.6    Wong, D.7    Dorovini-Zis, K.8
  • 36
    • 0027469626 scopus 로고
    • Increased interleukin-6 levels in cerebrospinal fluid foilowing subarachnoid hemorrhage
    • Matbiesen, T.; Anderson, B.; Loftenius, A.; von Holst, H. Increased interleukin-6 levels in cerebrospinal fluid foilowing subarachnoid hemorrhage. J. Neurosurg. 1993, 78, 562-567.
    • (1993) J. Neurosurg , vol.78 , pp. 562-567
    • Matbiesen, T.1    Anderson, B.2    Loftenius, A.3    von Holst, H.4
  • 37
    • 0025946766 scopus 로고
    • Increased plasma and ventricular interleukm-6 levels in head injured patients
    • McClain, C.J.; Cohen, D.; Phyllips. R.; Ott, L. and Young, B. Increased plasma and ventricular interleukm-6 levels in head injured patients. J. Lab. Clin. Med. 1991, 118, 225-230.
    • (1991) J. Lab. Clin. Med , vol.118 , pp. 225-230
    • McClain, C.J.1    Cohen, D.2    Phyllips, R.3    Ott, L.4    Young, B.5
  • 39
    • 0031693557 scopus 로고    scopus 로고
    • Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain
    • Rosenberg, G.A.; Estrada, E.Y.; Dencoff, J.E. Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain. Stroke 1998, 29(10), 2189-95.
    • (1998) Stroke , vol.29 , Issue.10 , pp. 2189-2195
    • Rosenberg, G.A.1    Estrada, E.Y.2    Dencoff, J.E.3
  • 40
    • 0035889079 scopus 로고    scopus 로고
    • Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha
    • Robertson, J.; Beaulieu, J.M.; Doroudchi, M.M.; Durham, H.D.; Julien, J.P.; Mushynski, W.E. Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha. J. Cell Biol. 2001, 155(2), 217-26.
    • (2001) J. Cell Biol , vol.155 , Issue.2 , pp. 217-226
    • Robertson, J.1    Beaulieu, J.M.2    Doroudchi, M.M.3    Durham, H.D.4    Julien, J.P.5    Mushynski, W.E.6
  • 42
    • 0031005797 scopus 로고    scopus 로고
    • TNF-alpha pretreatment induces protective effects against focal cerebral ischemia in mice
    • Nawashiro, H.; Tasaki, K.; Ruetzler, C.A.; Hallenbeck, J.M. TNF-alpha pretreatment induces protective effects against focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 1997, 17(5), 483-90.
    • (1997) J. Cereb. Blood Flow Metab , vol.17 , Issue.5 , pp. 483-490
    • Nawashiro, H.1    Tasaki, K.2    Ruetzler, C.A.3    Hallenbeck, J.M.4
  • 44
    • 0034046857 scopus 로고    scopus 로고
    • Inflammatory activation of human brain endothelial cells by hypoxic astrocytes in vitro is mediated by IL-1beta
    • Zhang, W.; Smith, C.; Howlett, C.; Stanimirovic, D. Inflammatory activation of human brain endothelial cells by hypoxic astrocytes in vitro is mediated by IL-1beta. J. Cereb. Blood Flow Metab. 2000, 20(6), 967-78.
    • (2000) J. Cereb. Blood Flow Metab , vol.20 , Issue.6 , pp. 967-978
    • Zhang, W.1    Smith, C.2    Howlett, C.3    Stanimirovic, D.4
  • 45
    • 0034094602 scopus 로고    scopus 로고
    • Exchange transfusion with fluorocarbon for studying synaptically evoked optical signal in rat cortex
    • Nomura, Y.; Fujii, F.; Sato, C.; Nemoto, M.; Tamura, M. Exchange transfusion with fluorocarbon for studying synaptically evoked optical signal in rat cortex. Brain Res. Brain Res. Protoc. 2000, 5(1), 10-5.
    • (2000) Brain Res. Brain Res. Protoc , vol.5 , Issue.1 , pp. 10-15
    • Nomura, Y.1    Fujii, F.2    Sato, C.3    Nemoto, M.4    Tamura, M.5
  • 46
    • 0344141389 scopus 로고    scopus 로고
    • Prolonged and concomitant induction of astroglial immunoreactivity of interleukin-1beta and interleukin-6 in the rat hippocampus after transient global ischemia
    • Orzyłowska, O.; Oderfeld-Nowak, B.; Zaremba, M.; Januszewski, S.; Mossakowski, M. Prolonged and concomitant induction of astroglial immunoreactivity of interleukin-1beta and interleukin-6 in the rat hippocampus after transient global ischemia. Neurosci. Lett. 1999, 263(1), 72-6.
    • (1999) Neurosci. Lett , vol.263 , Issue.1 , pp. 72-76
    • Orzyłowska, O.1    Oderfeld-Nowak, B.2    Zaremba, M.3    Januszewski, S.4    Mossakowski, M.5
  • 48
    • 0344972923 scopus 로고    scopus 로고
    • Ischemic stroke is associated with a systemic increase of blood mononuclear cells expressing interleukin-8 mRNA
    • Kostulas, N.; Kivisäkk, P.; Huang, Y.; Matusevicius, D.; Kostulas, V.; Link, H. Ischemic stroke is associated with a systemic increase of blood mononuclear cells expressing interleukin-8 mRNA. Stroke 1998, 29(2), 462-6.
    • (1998) Stroke , vol.29 , Issue.2 , pp. 462-466
    • Kostulas, N.1    Kivisäkk, P.2    Huang, Y.3    Matusevicius, D.4    Kostulas, V.5    Link, H.6
  • 51
    • 0036908651 scopus 로고    scopus 로고
    • The many faces of tumor necrosis factor in stroke
    • Hallenbeck, J.M. The many faces of tumor necrosis factor in stroke. Nat. Med. 2002, 8, 1363-1368.
    • (2002) Nat. Med , vol.8 , pp. 1363-1368
    • Hallenbeck, J.M.1
  • 52
    • 0028220499 scopus 로고
    • Proinflammatory cytokines in serum of patients with acute cerebral ischemia, kinetics of secretion and relation to the extent of brain damage and outcome of disease
    • Fassbender, K.; Rossol, S.; Kammer, T.; Daffertshofer, M.; Wirth, S.; Dollman, M.; Hennerici, M.Proinflammatory cytokines in serum of patients with acute cerebral ischemia, kinetics of secretion and relation to the extent of brain damage and outcome of disease. J. Neurol. Sci. 1994, 122, 135-139.
    • (1994) J. Neurol. Sci , vol.1 , Issue.22 , pp. 135-139
    • Fassbender, K.1    Rossol, S.2    Kammer, T.3    Daffertshofer, M.4    Wirth, S.5    Dollman, M.6    Hennerici, M.7
  • 54
  • 55
    • 0033795665 scopus 로고    scopus 로고
    • Proinflammatory cytokines and early neurological worsening in ischemic stroke
    • Vila, N.; Castillo, J.; Davalos, A.; Chamorro, A. Proinflammatory cytokines and early neurological worsening in ischemic stroke. Stroke 2000, 31, 2325-2329.
    • (2000) Stroke , vol.31 , pp. 2325-2329
    • Vila, N.1    Castillo, J.2    Davalos, A.3    Chamorro, A.4
  • 57
    • 34547598359 scopus 로고    scopus 로고
    • Administration of hematopoietic cytokines increases the expression of anti-inflammatory cytokine (IL-10) mRNA in the subacute phase after stroke
    • Morita, Y.; Takizawa, S.; Kamiguchi, H.; Uesugi, T.; Kawada, H.; Takagi, S. Administration of hematopoietic cytokines increases the expression of anti-inflammatory cytokine (IL-10) mRNA in the subacute phase after stroke. Neurosci. Res. 2007, 58, 356-360.
    • (2007) Neurosci. Res , vol.58 , pp. 356-360
    • Morita, Y.1    Takizawa, S.2    Kamiguchi, H.3    Uesugi, T.4    Kawada, H.5    Takagi, S.6
  • 58
    • 55049111080 scopus 로고    scopus 로고
    • Pro-inflammatory and anti-inflammatory cytokines in acute ischemic stroke and their relation to early neurological deficit and stroke out come
    • Kes, V.B.; Simundic, A.M.; Nikolac, N.; Topic, E.; Demarin, V. Pro-inflammatory and anti-inflammatory cytokines in acute ischemic stroke and their relation to early neurological deficit and stroke out come. Clin. Biochem. 2008, 41, 1330-1334.
    • (2008) Clin. Biochem , vol.41 , pp. 1330-1334
    • Kes, V.B.1    Simundic, A.M.2    Nikolac, N.3    Topic, E.4    Demarin, V.5
  • 59
    • 33750071449 scopus 로고    scopus 로고
    • Immunoinflammatory activation during the acute phase of lacunar and non-lacunar ischemic stroke, association with time of onset and diabetic state
    • Licata, G.; Tuttolomondo, A.; Corrao, S.; Di Raimondo, D.; Fernandez, P.; Caruso, C.; Avellone, G.; Pinto, A. Immunoinflammatory activation during the acute phase of lacunar and non-lacunar ischemic stroke, association with time of onset and diabetic state Int. J. Immunopathol. Pharmacol. 2006, 19(3), 639-46.
    • (2006) Int. J. Immunopathol. Pharmacol , vol.19 , Issue.3 , pp. 639-646
    • Licata, G.1    Tuttolomondo, A.2    Corrao, S.3    Di Raimondo, D.4    Fernandez, P.5    Caruso, C.6    Avellone, G.7    Pinto, A.8
  • 60
    • 66149173528 scopus 로고    scopus 로고
    • Immuno-inflammatory activation in acute cardio-embolic strokes in comparison with other subtypes of ischaemic stroke
    • Licata, G.; Tuttolomondo, A.; Raimondo, D.D.; Corrao, S.; Sciacca, R.D.; Pinto, A. Immuno-inflammatory activation in acute cardio-embolic strokes in comparison with other subtypes of ischaemic stroke. Thromb. Haemost. 2009, 101(5), 929-37.
    • (2009) Thromb. Haemost , vol.101 , Issue.5 , pp. 929-937
    • Licata, G.1    Tuttolomondo, A.2    Raimondo, D.D.3    Corrao, S.4    Sciacca, R.D.5    Pinto, A.6
  • 61
    • 0027514354 scopus 로고    scopus 로고
    • Adams, H.P.; Bendixen, B.H.; Kappelle, J.; Biller, J.; Love, B.; Gordon, M.D.; Marsh, E.E. and the TOAST Investigators. Classification of subtype of acute ischemic stroke. Stroke 1993, e24, 358.
    • Adams, H.P.; Bendixen, B.H.; Kappelle, J.; Biller, J.; Love, B.; Gordon, M.D.; Marsh, E.E. and the TOAST Investigators. Classification of subtype of acute ischemic stroke. Stroke 1993, e24, 358.
  • 63
    • 0030698685 scopus 로고    scopus 로고
    • Antileukocyte adhesion therapy, preclinical trials and combination therapy
    • Clark, W.M.; Zivin, J.A. Antileukocyte adhesion therapy, preclinical trials and combination therapy. Neurology 1997, 49(suppl 4), S32-S38.
    • (1997) Neurology , vol.49 , Issue.SUPPL. 4
    • Clark, W.M.1    Zivin, J.A.2
  • 65
  • 66
    • 0037335934 scopus 로고    scopus 로고
    • Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke
    • Vila, N.; Castillo, J.; Dávalos, A.; Esteve, A.; Planas, A.M.; Chamorro, A. Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke. Stroke 2003, 34(3), 671-5.
    • (2003) Stroke , vol.34 , Issue.3 , pp. 671-675
    • Vila, N.1    Castillo, J.2    Dávalos, A.3    Esteve, A.4    Planas, A.M.5    Chamorro, A.6
  • 67
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello, C.A. Biologic basis for interleukin-1 in disease. Blood 1996, 87(6), 2095-147.
    • (1996) Blood , vol.87 , Issue.6 , pp. 2095-2147
    • Dinarello, C.A.1
  • 68
    • 0031831906 scopus 로고    scopus 로고
    • Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist
    • Dinarello, C.A. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int. Rev. Immunol. 1998, 16(5-6), 457-99.
    • (1998) Int. Rev. Immunol , vol.16 , Issue.5-6 , pp. 457-499
    • Dinarello, C.A.1
  • 71
    • 0029042924 scopus 로고
    • Cerebral hypoxiaischemia stimulates cytokine gene expression in perinatal rats
    • Szaflarski, J.; Burtrum, D.; Silverstein, F.S. Cerebral hypoxiaischemia stimulates cytokine gene expression in perinatal rats. Stroke. 1995, 26(6), 1093-100.
    • (1995) Stroke , vol.26 , Issue.6 , pp. 1093-1100
    • Szaflarski, J.1    Burtrum, D.2    Silverstein, F.S.3
  • 72
    • 0034534995 scopus 로고    scopus 로고
    • Interleukin 1 in the brain, biology, pathology and therapeutic target
    • Rothwell, N.J.; Luheshi, G.N. Interleukin 1 in the brain, biology, pathology and therapeutic target. Trends Neurosci. 2000, 23(12), 618-25
    • (2000) Trends Neurosci , vol.23 , Issue.12 , pp. 618-625
    • Rothwell, N.J.1    Luheshi, G.N.2
  • 73
    • 0030789773 scopus 로고    scopus 로고
    • Cortical protection by localized striatal injection of IL-1ra following cerebral ischemia in the rat
    • Stroemer, R.P.; Rothwell, N.J. Cortical protection by localized striatal injection of IL-1ra following cerebral ischemia in the rat. J. Cereb. Blood Flow Metab. 1997, 17(6), 597-604.
    • (1997) J. Cereb. Blood Flow Metab , vol.17 , Issue.6 , pp. 597-604
    • Stroemer, R.P.1    Rothwell, N.J.2
  • 74
    • 0029035825 scopus 로고
    • Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain
    • Betz, A.L.; Yang, G.Y.; Davidson, B.L. Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J. Cereb. Blood Flow Metab. 1995, 15(4), 547-551.
    • (1995) J. Cereb. Blood Flow Metab , vol.15 , Issue.4 , pp. 547-551
    • Betz, A.L.1    Yang, G.Y.2    Davidson, B.L.3
  • 75
    • 0029865092 scopus 로고    scopus 로고
    • Peripheral administration of Interleukin-1 Receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat
    • Relton, J.K.; Martin, D.; Thompson, R.C.; Russell, D.A. Peripheral administration of Interleukin-1 Receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat. Exp. Neurol. 1996, 138(2), 206-213.
    • (1996) Exp. Neurol , vol.138 , Issue.2 , pp. 206-213
    • Relton, J.K.1    Martin, D.2    Thompson, R.C.3    Russell, D.A.4
  • 76
    • 0028630590 scopus 로고
    • The interleukin-1 receptor antagonist (rhIL-1ra) protects against cerebral infarction in a rat model of hypoxia-ischemia
    • Martin, D.; Chinookoswong, N.; Miller, G. The interleukin-1 receptor antagonist (rhIL-1ra) protects against cerebral infarction in a rat model of hypoxia-ischemia. Exp. Neurol. 1994, 130(2), 362-7.
    • (1994) Exp. Neurol , vol.130 , Issue.2 , pp. 362-367
    • Martin, D.1    Chinookoswong, N.2    Miller, G.3
  • 77
    • 0029744418 scopus 로고    scopus 로고
    • Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat
    • Loddick, S.A.; Rothwell, N.J. Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat. J. Cereb. Blood Flow Metab. 1996, 16(5), 932-934.
    • (1996) J. Cereb. Blood Flow Metab , vol.16 , Issue.5 , pp. 932-934
    • Loddick, S.A.1    Rothwell, N.J.2
  • 78
    • 0344301879 scopus 로고    scopus 로고
    • Exacerbation of ischemic brain damage by localized striatal injection of interleukin-1beta in the rat
    • Stroemer, R.P.; Rothwell, N.J. Exacerbation of ischemic brain damage by localized striatal injection of interleukin-1beta in the rat. J. Cereb. Blood Flow Metab. 1998, 18(8), 833-839.
    • (1998) J. Cereb. Blood Flow Metab , vol.18 , Issue.8 , pp. 833-839
    • Stroemer, R.P.1    Rothwell, N.J.2
  • 79
    • 0142153881 scopus 로고    scopus 로고
    • Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat
    • Mulcahy, N.J.; Ross, J.; Rothwell, N.J.; Loddick, S.A. Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat. Br. J. Pharmacol. 2003, 140(3), 471-476.
    • (2003) Br. J. Pharmacol , vol.140 , Issue.3 , pp. 471-476
    • Mulcahy, N.J.1    Ross, J.2    Rothwell, N.J.3    Loddick, S.A.4
  • 81
    • 0028239555 scopus 로고
    • Recombinant human interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome, results from a randomised, double blind, placebo controlled trial
    • Fisher, C.J.; Dhainaut, J.A.; Opal, S.M.; Pribble, J.P.; Balk, R.A.; Slotman, G.J.; Iberti, T.J.; Rackow, E.C.; Greenman, R.L. Recombinant human interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome, results from a randomised, double blind, placebo controlled trial. JAMA 1994, 271, 1836-1843.
    • (1994) JAMA , vol.271 , pp. 1836-1843
    • Fisher, C.J.1    Dhainaut, J.A.2    Opal, S.M.3    Pribble, J.P.4    Balk, R.A.5    Slotman, G.J.6    Iberti, T.J.7    Rackow, E.C.8    Greenman, R.L.9
  • 82
    • 0036845130 scopus 로고    scopus 로고
    • Long term safety and maintenance of clinical improvement following treatment with Anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis
    • Nuki, G.; Bresnihan, B.; Bear, M.B.; McCabe, D. Long term safety and maintenance of clinical improvement following treatment with Anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis. Arthritis Rheum. 2002, 46, 2838-2846.
    • (2002) Arthritis Rheum , vol.46 , pp. 2838-2846
    • Nuki, G.1    Bresnihan, B.2    Bear, M.B.3    McCabe, D.4
  • 83
    • 39849105534 scopus 로고    scopus 로고
    • Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage
    • Gueorguieva, I.; Clark, S.R.; McMahon, C.J.; Scarth, S.; Rothwell, N.J.; Tyrrell, P.J.; Hopkins, S.J.; Rowland, M. Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage. Br. J. Clin. Pharmacol. 2008, 65(3), 317-325.
    • (2008) Br. J. Clin. Pharmacol , vol.65 , Issue.3 , pp. 317-325
    • Gueorguieva, I.1    Clark, S.R.2    McMahon, C.J.3    Scarth, S.4    Rothwell, N.J.5    Tyrrell, P.J.6    Hopkins, S.J.7    Rowland, M.8
  • 85
    • 0034045956 scopus 로고    scopus 로고
    • Anti-inflammatory cytokines and cytokine antagonists
    • Standiford, T.J. Anti-inflammatory cytokines and cytokine antagonists. Curr. Pharm. Des. 2000, 6(6), 633-649.
    • (2000) Curr. Pharm. Des , vol.6 , Issue.6 , pp. 633-649
    • Standiford, T.J.1
  • 86
    • 0031051349 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor and amelioration of brain infarction in mice
    • Nawashiro, H.; Martin, D.; Hallenbeck, J.M. Inhibition of tumor necrosis factor and amelioration of brain infarction in mice. J. Cereb. Blood Flow Metab. 1997, 17(2), 229-32.
    • (1997) J. Cereb. Blood Flow Metab , vol.17 , Issue.2 , pp. 229-232
    • Nawashiro, H.1    Martin, D.2    Hallenbeck, J.M.3
  • 87
    • 0032410581 scopus 로고    scopus 로고
    • Cytokines in brain ischemia-the role of TNF alpha
    • Feuerstein, G.; Wang, X.; Barone, F.C. Cytokines in brain ischemia-the role of TNF alpha. Cell Mol. Neurobiol. 1998, 18(6), 695-701.
    • (1998) Cell Mol. Neurobiol , vol.18 , Issue.6 , pp. 695-701
    • Feuerstein, G.1    Wang, X.2    Barone, F.C.3
  • 88
    • 0032557738 scopus 로고    scopus 로고
    • Inhibition of TNFalpha attenuates infarct volume and ICAM-1 expression in ischemic mouse brain
    • Yang, G.Y.; Gong, C.; Qin, Z.; Ye, W.; Mao, Y.; Bertz, A.L. Inhibition of TNFalpha attenuates infarct volume and ICAM-1 expression in ischemic mouse brain. Neuroreport. 1998, 9(9), 2131-2134.
    • (1998) Neuroreport , vol.9 , Issue.9 , pp. 2131-2134
    • Yang, G.Y.1    Gong, C.2    Qin, Z.3    Ye, W.4    Mao, Y.5    Bertz, A.L.6
  • 96
    • 0034741796 scopus 로고    scopus 로고
    • Neuronal localization of the TNFalpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques
    • Skovronsky, D.M.; Fath, S.; Lee, V.M.; Milla, M.E. Neuronal localization of the TNFalpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques. J. Neurobiol. 2001, 49(1), 40-6.
    • (2001) J. Neurobiol , vol.49 , Issue.1 , pp. 40-46
    • Skovronsky, D.M.1    Fath, S.2    Lee, V.M.3    Milla, M.E.4
  • 97
    • 0034961544 scopus 로고    scopus 로고
    • Astrocyte and endothelial cell expression of ADAM 17 (TACE) in adult human CNS
    • Goddard, D.R.; Bunning, R.A.; Woodroofe, M.N. Astrocyte and endothelial cell expression of ADAM 17 (TACE) in adult human CNS. Glia 2001, 34(4), 267-271.
    • (2001) Glia , vol.34 , Issue.4 , pp. 267-271
    • Goddard, D.R.1    Bunning, R.A.2    Woodroofe, M.N.3
  • 99
    • 0842327251 scopus 로고    scopus 로고
    • Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia
    • Lee, S.R.; Tsuji, K.; Lee, S.R.; Lo, E.H. Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia. J. Neurosci. 2004, 24(3), 671-678.
    • (2004) J. Neurosci , vol.24 , Issue.3 , pp. 671-678
    • Lee, S.R.1    Tsuji, K.2    Lee, S.R.3    Lo, E.H.4
  • 100
    • 0035370582 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitor KB-R7785, attenuates brain damage resulting from permanent focal cerebral ischemia in mice
    • Jiang, X.; Namura, S.; Nagata, I. Matrix metalloproteinase inhibitor KB-R7785, attenuates brain damage resulting from permanent focal cerebral ischemia in mice. Neurosci. Lett. 2001, 305(1), 41-44.
    • (2001) Neurosci. Lett , vol.305 , Issue.1 , pp. 41-44
    • Jiang, X.1    Namura, S.2    Nagata, I.3
  • 101
    • 0033638508 scopus 로고    scopus 로고
    • Role for matrix metalloproteinase 9 after focal cerebral ischemia, effects of gene knockout and enzyme inhibition with BB-94
    • Asahi, M.; Asahi, K.; Jung, J.C.; del Zoppo, G.J.; Fini, M.E.; Lo, E.H. Role for matrix metalloproteinase 9 after focal cerebral ischemia, effects of gene knockout and enzyme inhibition with BB-94. J. Cereb. Blood Flow Metab. 2000, 20(12), 1681-1689.
    • (2000) J. Cereb. Blood Flow Metab , vol.20 , Issue.12 , pp. 1681-1689
    • Asahi, M.1    Asahi, K.2    Jung, J.C.3    del Zoppo, G.J.4    Fini, M.E.5    Lo, E.H.6
  • 102
    • 0033562658 scopus 로고    scopus 로고
    • CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons
    • Martin, A.; Herr, I.; Jeremias, I.; Hahne, M.; Brandt, R.; Vogel, J.; Schenkel, J.; Herdegen, T.; Debatin, K.M. CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons. J. Neurosci. 1999, 19(10), 3809-3817.
    • (1999) J. Neurosci , vol.19 , Issue.10 , pp. 3809-3817
    • Martin, A.1    Herr, I.2    Jeremias, I.3    Hahne, M.4    Brandt, R.5    Vogel, J.6    Schenkel, J.7    Herdegen, T.8    Debatin, K.M.9
  • 103
    • 0031963924 scopus 로고    scopus 로고
    • Circulating antibody against tumor necrosis factor-alpha protects rat brain from reperfusion injury
    • Lavine, S.D.; Hofman, F.M.; Zlokovic, B.V. Circulating antibody against tumor necrosis factor-alpha protects rat brain from reperfusion injury. J. Cereb. Blood Flow Metab. 1998, 18(1), 52-58.
    • (1998) J. Cereb. Blood Flow Metab , vol.18 , Issue.1 , pp. 52-58
    • Lavine, S.D.1    Hofman, F.M.2    Zlokovic, B.V.3
  • 104
    • 0033562658 scopus 로고    scopus 로고
    • CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons
    • Martin-Villalba, A.; Herr, I.; Jeremias, I.; Hahne, M.; Brandt, R.; Vogel, J.; Schenkel, J.; Herdegen, T.; Debatin, K.M. CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons. J. Neurosci. 1999, 19 (10), 3809-3817.
    • (1999) J. Neurosci , vol.19 , Issue.10 , pp. 3809-3817
    • Martin-Villalba, A.1    Herr, I.2    Jeremias, I.3    Hahne, M.4    Brandt, R.5    Vogel, J.6    Schenkel, J.7    Herdegen, T.8    Debatin, K.M.9
  • 105
    • 0027420579 scopus 로고
    • Tumor necrosis factor, an updated review of its biology
    • Tracey, K.J.; Cerami, A. Tumor necrosis factor, an updated review of its biology. Crit. Care Med. 1993, 21(10 Suppl), S415-422.
    • (1993) Crit. Care Med , vol.21 , Issue.10 SUPPL.
    • Tracey, K.J.1    Cerami, A.2
  • 106
    • 0027315234 scopus 로고
    • The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-alpha production by human mononuclear cells
    • Semmler, J.; Wachtel, H.; Endres, S. The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-alpha production by human mononuclear cells. Int. J. Immunopharmacol. 1993, 15(3), 409-413.
    • (1993) Int. J. Immunopharmacol , vol.15 , Issue.3 , pp. 409-413
    • Semmler, J.1    Wachtel, H.2    Endres, S.3
  • 109
    • 0026806822 scopus 로고
    • Poly(A) removal is the kinase-regulated step in tumor necrosis factor mRNA decay
    • Lieberman, A.P.; Pitha, P.M.; Shin, M.L. Poly(A) removal is the kinase-regulated step in tumor necrosis factor mRNA decay. J. Biol. Chem. 1992, 267(4), 2123-2126.
    • (1992) J. Biol. Chem , vol.267 , Issue.4 , pp. 2123-2126
    • Lieberman, A.P.1    Pitha, P.M.2    Shin, M.L.3
  • 110
    • 0029744885 scopus 로고    scopus 로고
    • Sounding the alarm, protein kinase cascades activated by stress and inflammation
    • Kyriakis, J.M.; Avruch, J. Sounding the alarm, protein kinase cascades activated by stress and inflammation. J. Biol. Chem. 1996, 271(40), 24313-6.
    • (1996) J. Biol. Chem , vol.271 , Issue.40 , pp. 24313-24316
    • Kyriakis, J.M.1    Avruch, J.2
  • 111
    • 0030808984 scopus 로고    scopus 로고
    • Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase
    • Kummer, J.L.; Rao, P.K.; Heidenreich, K.A. Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase. J. Biol. Chem. 1997, 272(33), 20490-4.
    • (1997) J. Biol. Chem , vol.272 , Issue.33 , pp. 20490-20494
    • Kummer, J.L.1    Rao, P.K.2    Heidenreich, K.A.3
  • 112
    • 0033810404 scopus 로고    scopus 로고
    • Therapeutic potential of antiinflammatory drugs in focal stroke
    • Barone, F.C.; Parsons, A.A. Therapeutic potential of antiinflammatory drugs in focal stroke. Expert Opin. Investig. Drugs 2000, 9(10), 2281-306
    • (2000) Expert Opin. Investig. Drugs , vol.9 , Issue.10 , pp. 2281-2306
    • Barone, F.C.1    Parsons, A.A.2
  • 114
    • 0032508615 scopus 로고    scopus 로고
    • Stress-activated protein kinase/Jun N-terminal kinase is required for interleukin (IL)-1-induced IL-6 and IL-8 gene expression in the human epidermal carcinoma cell line KB
    • Krause, A.J.; Holtmann, H.; Eickemeier, S.; Winzen, R.; Szamel, M.; Resch, K.; Saklatvala Kracht, M.J. Stress-activated protein kinase/Jun N-terminal kinase is required for interleukin (IL)-1-induced IL-6 and IL-8 gene expression in the human epidermal carcinoma cell line KB. Biol. Chem. 1998, 273(37), 23681-23689.
    • (1998) Biol. Chem , vol.273 , Issue.37 , pp. 23681-23689
    • Krause, A.J.1    Holtmann, H.2    Eickemeier, S.3    Winzen, R.4    Szamel, M.5    Resch, K.6    Saklatvala Kracht, M.J.7
  • 115
    • 0029983730 scopus 로고    scopus 로고
    • The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
    • Beyaert, R.; Cuenda, A.; Vanden Berghe, W.; Plaisance, S.; Lee, J.C.; Haegeman, G.; Cohen, P.; Fiers, W. The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. EMBO J. 1996, 15(8), 1914-1923.
    • (1996) EMBO J , vol.15 , Issue.8 , pp. 1914-1923
    • Beyaert, R.1    Cuenda, A.2    Vanden Berghe, W.3    Plaisance, S.4    Lee, J.C.5    Haegeman, G.6    Cohen, P.7    Fiers, W.8
  • 117
    • 0001381982 scopus 로고    scopus 로고
    • Selective inhibition of p38 mitogen activated kinase reduces brain injury and neurological deficits in rat focal stroke models
    • Barone, F.C.; Feuerstein, G.Z.; White, R.F. Selective inhibition of p38 mitogen activated kinase reduces brain injury and neurological deficits in rat focal stroke models. J. Cereb. Blood Flow Metab. 1999, 19 (Suppl 1), 5613.
    • (1999) J. Cereb. Blood Flow Metab , vol.19 , Issue.SUPPL. 1 , pp. 5613
    • Barone, F.C.1    Feuerstein, G.Z.2    White, R.F.3
  • 118
    • 0033168727 scopus 로고    scopus 로고
    • Innate and adaptive immune responses can be beneficial for CNS repair
    • Schwartz, M.; Moalem, G.; Leibowitz-Amit, R.; Cohen, I.R. Innate and adaptive immune responses can be beneficial for CNS repair. Trends Neurosci. 1999, 22(7), 295-299.
    • (1999) Trends Neurosci , vol.22 , Issue.7 , pp. 295-299
    • Schwartz, M.1    Moalem, G.2    Leibowitz-Amit, R.3    Cohen, I.R.4
  • 119
    • 0027935309 scopus 로고
    • Leukocyte-endothelial adhesion molecules
    • Carlos, T.M.; Harlan, J.M. Leukocyte-endothelial adhesion molecules. Blood 1994, 84, 2068-2101.
    • (1994) Blood , vol.84 , pp. 2068-2101
    • Carlos, T.M.1    Harlan, J.M.2
  • 120
    • 0028147428 scopus 로고
    • P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion
    • Okada, Y.; Copeland, B.R.; Mori, E.; Tung, M.M.; Thomas, W.S.; del Zoppo, G.J. P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion. Stroke 1994, 25, 202-211. 29.
    • (1994) Stroke , vol.25 , Issue.202-211 , pp. 29
    • Okada, Y.1    Copeland, B.R.2    Mori, E.3    Tung, M.M.4    Thomas, W.S.5    del Zoppo, G.J.6
  • 121
    • 0028854369 scopus 로고
    • Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex
    • Jander, S.; Kraemer, M.; Schroeter, M.; Witte, O.W.; Stoll, G. Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex. J. Cereb. Blood Flow Metab. 1995, 15, 42-51.
    • (1995) J. Cereb. Blood Flow Metab , vol.15 , pp. 42-51
    • Jander, S.1    Kraemer, M.2    Schroeter, M.3    Witte, O.W.4    Stoll, G.5
  • 123
    • 0029824242 scopus 로고    scopus 로고
    • E-selectin appears in nonischemic tissue during experimental focal cerebral ischemia
    • Haring, H.P.; Berg, E.L.; Tsurushita, N.; Tagaya, M.; del Zoppo, G.J. E-selectin appears in nonischemic tissue during experimental focal cerebral ischemia. Stroke 1996, 27, 1386-1391.
    • (1996) Stroke , vol.27 , pp. 1386-1391
    • Haring, H.P.1    Berg, E.L.2    Tsurushita, N.3    Tagaya, M.4    del Zoppo, G.J.5
  • 125
    • 0030876911 scopus 로고    scopus 로고
    • Expressions of P-selectin- and HSP72-like immunoreactivities in rat brain after transient middle cerebral artery occlusion
    • Suzuki, H.; Abe, K.; Tojo, S.; Morooka, S.; Kimura, K.; Mizugaki, M.; Itoyama, Y. Expressions of P-selectin- and HSP72-like immunoreactivities in rat brain after transient middle cerebral artery occlusion. Brain Res. 1997, 759, 321-329.
    • (1997) Brain Res , vol.759 , pp. 321-329
    • Suzuki, H.1    Abe, K.2    Tojo, S.3    Morooka, S.4    Kimura, K.5    Mizugaki, M.6    Itoyama, Y.7
  • 126
    • 0032473602 scopus 로고    scopus 로고
    • The expression of Pand E-selectins in three models of middle cerebral artery occlusion
    • Zhang, R.; Chopp, M.; Zhang, Z.; Jiang, N.; Powers, C. The expression of Pand E-selectins in three models of middle cerebral artery occlusion. Brain Res. 1998, 785, 207-214.
    • (1998) Brain Res , vol.785 , pp. 207-214
    • Zhang, R.1    Chopp, M.2    Zhang, Z.3    Jiang, N.4    Powers, C.5
  • 127
    • 0028244894 scopus 로고
    • Increased expression of ICAM-1 during reoxygenation in brain endothelial cells
    • Hess, D.C.; Zhao, W.; Carroll, J.; McEachin, M.; Buchanan, K. Increased expression of ICAM-1 during reoxygenation in brain endothelial cells. Stroke 1994, 25, 1463-1467.
    • (1994) Stroke , vol.25 , pp. 1463-1467
    • Hess, D.C.1    Zhao, W.2    Carroll, J.3    McEachin, M.4    Buchanan, K.5
  • 128
    • 0031298625 scopus 로고    scopus 로고
    • Increase in surface expression of ICAM-1, VCAM-1 and E-selectin in human cerebromicrovascular endothelial cells subjected to ischemia-like insults
    • Stanimirovic, D.B.; Wong, J.; Shapiro, A.; Durkin, J.P. Increase in surface expression of ICAM-1, VCAM-1 and E-selectin in human cerebromicrovascular endothelial cells subjected to ischemia-like insults. Acta Neurochir. Suppl. (Wien). 1997, 70, 12-16.
    • (1997) Acta Neurochir. Suppl. (Wien) , vol.70 , pp. 12-16
    • Stanimirovic, D.B.1    Wong, J.2    Shapiro, A.3    Durkin, J.P.4
  • 129
    • 0032486242 scopus 로고    scopus 로고
    • NF-kappa B is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells
    • Howard, E.F.; Chen, Q.; Cheng, C.; Carroll, J.E.; Hess, D. NF-kappa B is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells. Neurosci. Lett. 1998, 248, 199-203.
    • (1998) Neurosci. Lett , vol.248 , pp. 199-203
    • Howard, E.F.1    Chen, Q.2    Cheng, C.3    Carroll, J.E.4    Hess, D.5
  • 130
    • 0025301596 scopus 로고
    • Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system
    • Sobel, R.A.; Mitchell, M.E.; Fondren, G. Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system. Am. J. Pathol. 1990, 136, 1309-1316.
    • (1990) Am. J. Pathol , vol.136 , pp. 1309-1316
    • Sobel, R.A.1    Mitchell, M.E.2    Fondren, G.3
  • 131
    • 0027936452 scopus 로고
    • Role of angiogenesis in patients with cerebral ischemic stroke
    • Krupinski, J.; Kaluza, J.; Kumar, P.; Kumar, S.; Wang, J.M. Role of angiogenesis in patients with cerebral ischemic stroke. Stroke 1994, 25, 1794-179.
    • (1994) Stroke , vol.25 , pp. 1794-2179
    • Krupinski, J.1    Kaluza, J.2    Kumar, P.3    Kumar, S.4    Wang, J.M.5
  • 132
    • 0029808409 scopus 로고    scopus 로고
    • Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke
    • Lindsberg, P.J.; Carpen, O.; Paetau, A.; Karjalainen-Lindsberg, M.L.; Kaste, M. Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke. Circulation 1996, 94, 939-945.
    • (1996) Circulation , vol.94 , pp. 939-945
    • Lindsberg, P.J.1    Carpen, O.2    Paetau, A.3    Karjalainen-Lindsberg, M.L.4    Kaste, M.5
  • 133
    • 0027196122 scopus 로고
    • Circulating intercellular adhesion molecule-l levels and neutrophil adhesion in stroke
    • Clark, W.M.; Coull, B.M.; Briley, D.P.; Mainolfi, E. and Rotblein, R. Circulating intercellular adhesion molecule-l levels and neutrophil adhesion in stroke. J. Neuroimmunol. 1993, 44, 125-133
    • (1993) J. Neuroimmunol , vol.44 , pp. 125-133
    • Clark, W.M.1    Coull, B.M.2    Briley, D.P.3    Mainolfi, E.4    Rotblein, R.5
  • 135
    • 0028812403 scopus 로고
    • Adhesive glycoprotein CD 1 la and CD 18 are upregulated in leukocytes from patients with cerebral ischemia
    • Kim, J.S.; Chopp, M.; Chen, H.; Levine, S.R.; Carey, J.L. and Welch, K.M.A. Adhesive glycoprotein CD 1 la and CD 18 are upregulated in leukocytes from patients with cerebral ischemia. J. Neurol. Sci. 1995, 128, 45-50.
    • (1995) J. Neurol. Sci , vol.128 , pp. 45-50
    • Kim, J.S.1    Chopp, M.2    Chen, H.3    Levine, S.R.4    Carey, J.L.5    Welch, K.M.A.6
  • 136
    • 0031685143 scopus 로고    scopus 로고
    • The role of inflammation after acute stroke, utility of pursuing anti-adhesion molecule therapy
    • DeGraba, T.J. The role of inflammation after acute stroke, utility of pursuing anti-adhesion molecule therapy. Neurology 1998, 51(suppl 3), S62-S68.
    • (1998) Neurology , vol.51 , Issue.SUPPL. 3
    • DeGraba, T.J.1
  • 137
    • 0031848946 scopus 로고    scopus 로고
    • Safety, pharmacokinetics and biological activity of enlimomab (anti-ICAM-1 antibody), an open-label, dose escalation study in patients hospitalized for acute stroke
    • Schneider, D.; Berrouschot, J.; Brandt, T.; Hacke, W.; Ferbert, A.; Norris, S.H.; Polmar, S.H.; Schafer, E. Safety, pharmacokinetics and biological activity of enlimomab (anti-ICAM-1 antibody), an open-label, dose escalation study in patients hospitalized for acute stroke. Eur. Neurol. 1998, 40, 78-83.
    • (1998) Eur. Neurol , vol.40 , pp. 78-83
    • Schneider, D.1    Berrouschot, J.2    Brandt, T.3    Hacke, W.4    Ferbert, A.5    Norris, S.H.6    Polmar, S.H.7    Schafer, E.8
  • 138
    • 0033557749 scopus 로고    scopus 로고
    • Anti-ICAM-1 monoclonal antibody R6.5 (enlimomab) promotes activation of neutrophils in whole blood
    • Vuorte, J.; Lindsberg, P.J.; Kaste, M.; Meri, S.; Jansson, S.E.; Rothlein, R.; Repo, H. Anti-ICAM-1 monoclonal antibody R6.5 (enlimomab) promotes activation of neutrophils in whole blood. J. Immunol. 1999, 162, 2353-2357.
    • (1999) J. Immunol , vol.162 , pp. 2353-2357
    • Vuorte, J.1    Lindsberg, P.J.2    Kaste, M.3    Meri, S.4    Jansson, S.E.5    Rothlein, R.6    Repo, H.7
  • 139
    • 0035164475 scopus 로고    scopus 로고
    • Examination of several potential mechanisms for the negative outcome in a clinical stroke trial of enlimomab, a murine anti-human intercellular adhesion molecule-1 antibody, a bedsideto- bench study
    • Furuya, K.; Takeda, H.; Azhar, S.; McCarron, R.M.; Chen, Y.; Ruetzler, C.A.; Wolcott, K.M.; DeGraba, T.J.; Rothlein, R.; Hugli, T.E.; del Zoppo, G.J.; Hallenbeck, J.M. Examination of several potential mechanisms for the negative outcome in a clinical stroke trial of enlimomab, a murine anti-human intercellular adhesion molecule-1 antibody, a bedsideto- bench study. Stroke 2001, 32, 2665-2674.
    • (2001) Stroke , vol.32 , pp. 2665-2674
    • Furuya, K.1    Takeda, H.2    Azhar, S.3    McCarron, R.M.4    Chen, Y.5    Ruetzler, C.A.6    Wolcott, K.M.7    DeGraba, T.J.8    Rothlein, R.9    Hugli, T.E.10    del Zoppo, G.J.11    Hallenbeck, J.M.12
  • 141
    • 0031959973 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression increases after cerebral focal ischemia in rats, inhibition of matrix metalloproteinase-9 reduces infarct size
    • Romanic, A.M.; White, R.F.; Arleth, A.J.; Ohlstein, E.H.; Barone, F.C. Matrix metalloproteinase expression increases after cerebral focal ischemia in rats, inhibition of matrix metalloproteinase-9 reduces infarct size. Stroke 1998, 29(5), 1020-1030.
    • (1998) Stroke , vol.29 , Issue.5 , pp. 1020-1030
    • Romanic, A.M.1    White, R.F.2    Arleth, A.J.3    Ohlstein, E.H.4    Barone, F.C.5
  • 142
    • 0034893137 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression after human cardioembolic stroke, temporal profile and relation to neurological impairment
    • Montaner, J.; Alvarez-Sabín, J.; Molina, C.; Anglés, A.; Abilleira, S.; Arenillas, J.; González, M.A.; Monasterio, J. Matrix metalloproteinase expression after human cardioembolic stroke, temporal profile and relation to neurological impairment. Stroke 2001, 32(8), 1759-1766.
    • (2001) Stroke , vol.32 , Issue.8 , pp. 1759-1766
    • Montaner, J.1    Alvarez-Sabín, J.2    Molina, C.3    Anglés, A.4    Abilleira, S.5    Arenillas, J.6    González, M.A.7    Monasterio, J.8
  • 143
    • 0035207961 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression is related to hemorrhagic transformation after cardioembolic stroke
    • Montaner, J.; Alvarez-Sabín, J.; Molina, C.A.; Anglés, A.; Abilleira, S.; Arenillas, J.; Monasterio, J. Matrix metalloproteinase expression is related to hemorrhagic transformation after cardioembolic stroke. Stroke 2001, 32(12), 2762-2767.
    • (2001) Stroke , vol.32 , Issue.12 , pp. 2762-2767
    • Montaner, J.1    Alvarez-Sabín, J.2    Molina, C.A.3    Anglés, A.4    Abilleira, S.5    Arenillas, J.6    Monasterio, J.7
  • 144
    • 0041829250 scopus 로고    scopus 로고
    • Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients, influence of different therapies
    • Horstmann, S.; Kalb, P.; Koziol, J.; Gardner, H.; Wagner, S. Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients,
    • (2003) Stroke , vol.34 , Issue.9 , pp. 2165-2170
    • Horstmann, S.1    Kalb, P.2    Koziol, J.3    Gardner, H.4    Wagner, S.5
  • 145
    • 49349108336 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinase-9 attenuated neural progenitor cell migration after photothrombotic ischemia
    • Kang, S.S.; Kook, J.H.; Hwang, S.; Park, S.H.; Nam, S.C.; Kim, J.K. Inhibition of matrix metalloproteinase-9 attenuated neural progenitor cell migration after photothrombotic ischemia. Brain Res. 2008, 1228, 20-26.
    • (2008) Brain Res , vol.1228 , pp. 20-26
    • Kang, S.S.1    Kook, J.H.2    Hwang, S.3    Park, S.H.4    Nam, S.C.5    Kim, J.K.6
  • 146
    • 34547815675 scopus 로고    scopus 로고
    • A non-steroidal anti-inflammatory agent provides significant protection during focal ischemic stroke with decreased expression of matrix metalloproteinases
    • Wang, Y.; Deng, X.L.; Xiao, X.H.; Yuan, B.X. A non-steroidal anti-inflammatory agent provides significant protection during focal ischemic stroke with decreased expression of matrix metalloproteinases. Curr. Neurovasc. Res. 2007, 4(3), 176-183.
    • (2007) Curr. Neurovasc. Res , vol.4 , Issue.3 , pp. 176-183
    • Wang, Y.1    Deng, X.L.2    Xiao, X.H.3    Yuan, B.X.4
  • 147
    • 34247545017 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke
    • Caso, J.R.; Pradillo, J.M.; Hurtado, O.; Lorenzo, P.; Moro, M.A.; Lizasoain, I. Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation 2007, 115(12), 1599-1608.
    • (2007) Circulation , vol.115 , Issue.12 , pp. 1599-1608
    • Caso, J.R.1    Pradillo, J.M.2    Hurtado, O.3    Lorenzo, P.4    Moro, M.A.5    Lizasoain, I.6
  • 148
    • 41149112041 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke
    • Caso, J.R.; Pradillo, J.M.; Hurtado, O.; Leza, J.C.; Moro, M.A.; Lizasoain, I. Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke. Stroke 2008, 39(4), 1314-1322.
    • (2008) Stroke , vol.39 , Issue.4 , pp. 1314-1322
    • Caso, J.R.1    Pradillo, J.M.2    Hurtado, O.3    Leza, J.C.4    Moro, M.A.5    Lizasoain, I.6
  • 153
    • 0031718663 scopus 로고    scopus 로고
    • Inflammation and glial responses in ischemic brain lesions
    • Stoll, G.; Jander, S.; Schroeter, M. Inflammation and glial responses in ischemic brain lesions. Prog. Neurobiol. 1998, 56, 149-171.
    • (1998) Prog. Neurobiol , vol.56 , pp. 149-171
    • Stoll, G.1    Jander, S.2    Schroeter, M.3
  • 154
    • 0026667919 scopus 로고
    • Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke
    • Kochanek, P.M.; Hallenbeck, J.M. Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke 1992, 23, 1367-1379.
    • (1992) Stroke , vol.23 , pp. 1367-1379
    • Kochanek, P.M.1    Hallenbeck, J.M.2
  • 155
    • 0029780302 scopus 로고    scopus 로고
    • Dynamics of polymorphonuclear leukocyte accumulation in acute cerebral infarction and their correlation with brain tissue damage
    • Akopov, S.E.; Simonian, N.A.; Grigorian, G.S. Dynamics of polymorphonuclear leukocyte accumulation in acute cerebral infarction and their correlation with brain tissue damage. Stroke 1996, 27, 1739-1743.
    • (1996) Stroke , vol.27 , pp. 1739-1743
    • Akopov, S.E.1    Simonian, N.A.2    Grigorian, G.S.3
  • 156
    • 3142592393 scopus 로고    scopus 로고
    • Saleh, A.; Schroeter, M.; Jonkmanns, C.; Hartung, H.P.; Modder, U.; Jander, S. In vivo MRI of brain inflammation in human ischaemic stroke. Brain 2004, 127, 1670-1677. 6.
    • Saleh, A.; Schroeter, M.; Jonkmanns, C.; Hartung, H.P.; Modder, U.; Jander, S. In vivo MRI of brain inflammation in human ischaemic stroke. Brain 2004, 127, 1670-1677. 6.
  • 157
    • 0034764183 scopus 로고    scopus 로고
    • Dynamic patterns of USPIO enhancement can be observed in macrophages after ischemic brain damage
    • Rausch, M.; Sauter, A.; Frohlich, J.; Neubacher, U.; Radu, E.W.; Rudin, M. Dynamic patterns of USPIO enhancement can be observed in macrophages after ischemic brain damage. Magn. Reson. Med. 2001, 46, 1018-102.
    • (2001) Magn. Reson. Med , vol.46 , pp. 1018-1102
    • Rausch, M.1    Sauter, A.2    Frohlich, J.3    Neubacher, U.4    Radu, E.W.5    Rudin, M.6
  • 158
    • 74249106599 scopus 로고    scopus 로고
    • Yilmaz, A.; Fuchs, T.; Dietel, B.; Altendorf, R.; Cicha, I.; Stumpf, C.; Schellinger, P.; Blümcke, I.; Schwab, S.; Daniel, W.G.; Garlichs, C.D.; Kollmar, R. Transient decrease in circulating dendritic cell precursors after acute stroke - potential recruitment into the brain. Clin. Sci. (Lond). 2009, [Epub ahead of print].
    • Yilmaz, A.; Fuchs, T.; Dietel, B.; Altendorf, R.; Cicha, I.; Stumpf, C.; Schellinger, P.; Blümcke, I.; Schwab, S.; Daniel, W.G.; Garlichs, C.D.; Kollmar, R. Transient decrease in circulating dendritic cell precursors after acute stroke - potential recruitment into the brain. Clin. Sci. (Lond). 2009, [Epub ahead of print].
  • 159
    • 0242658540 scopus 로고    scopus 로고
    • In vivo monitoring of macrophage infiltration in experimental ischemic brain lesions by magnetic resonance imaging
    • Kleinschnitz, C.; Bendszus, M.; Frank, M.; Solymosi, L.; Toyka, K.V.; Stoll, G. In vivo monitoring of macrophage infiltration in experimental ischemic brain lesions by magnetic resonance imaging. J. Cereb. Blood Flow Metab. 2003, 23(11), 1356-1361.
    • (2003) J. Cereb. Blood Flow Metab , vol.23 , Issue.11 , pp. 1356-1361
    • Kleinschnitz, C.1    Bendszus, M.2    Frank, M.3    Solymosi, L.4    Toyka, K.V.5    Stoll, G.6
  • 160
    • 46149109247 scopus 로고    scopus 로고
    • Imaging of the inflammatory response in reperfusion injury after transient cerebral ischemia in rats, correlation of superparamagnetic iron oxide-enhanced magnetic resonance imaging with histopathology
    • Kim, J.; Kim, D.I.; Lee, S.K.; Kim, D.J.; Lee, J.E.; Ahn, S.K. Imaging of the inflammatory response in reperfusion injury after transient cerebral ischemia in rats, correlation of superparamagnetic iron oxide-enhanced magnetic resonance imaging with histopathology. Acta Radiol. 2008, 49(5), 580-588.
    • (2008) Acta Radiol , vol.49 , Issue.5 , pp. 580-588
    • Kim, J.1    Kim, D.I.2    Lee, S.K.3    Kim, D.J.4    Lee, J.E.5    Ahn, S.K.6
  • 162
    • 3843134242 scopus 로고    scopus 로고
    • Platelet-leukocyte-endothelial cell interactions after middle cerebral artery occlusion and reperfusion
    • Ishikawa, M.; Cooper, D.; Arumugam, T.V.; Zhang, J.H.; Nanda, A.; Granger, D.N. Platelet-leukocyte-endothelial cell interactions after middle cerebral artery occlusion and reperfusion. J. Cereb. Blood Flow Metab. 2004, 24(8), 907-915.
    • (2004) J. Cereb. Blood Flow Metab , vol.24 , Issue.8 , pp. 907-915
    • Ishikawa, M.1    Cooper, D.2    Arumugam, T.V.3    Zhang, J.H.4    Nanda, A.5    Granger, D.N.6
  • 164
    • 1642281919 scopus 로고    scopus 로고
    • Beneficial effects of CD39/ecto-nucleoside triphosphate diphosphohydrolase-1 in murine intestinal ischemia-reperfusion injury
    • Guckelberger, O.; Sun, X.F.; Sévigny, J.; Imai, M.; Kaczmarek, E.; Enjyoji, K.; Kruskal, J.B.; Robson, S.C. Beneficial effects of CD39/ecto-nucleoside triphosphate diphosphohydrolase-1 in murine intestinal ischemia-reperfusion injury. Thromb. Haemost. 2004, 91(3), 576-586.
    • (2004) Thromb. Haemost , vol.91 , Issue.3 , pp. 576-586
    • Guckelberger, O.1    Sun, X.F.2    Sévigny, J.3    Imai, M.4    Kaczmarek, E.5    Enjyoji, K.6    Kruskal, J.B.7    Robson, S.C.8


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