CD36: A class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism

Journal of Clinical Investigation

Volumn 108, Issue 6, 2001, Pages 785-791

  Febbraio, M ^a   Hajjar, D P ^a   Silverstein, R L ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; SCAVENGER RECEPTOR;

ANGIOGENESIS; ANTIGEN PRESENTATION; APOPTOSIS; ATHEROGENESIS; ATHEROSCLEROSIS; GENE EXPRESSION REGULATION; INFLAMMATION; LIPID METABOLISM; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; REVIEW;

EID: 0034833822     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI14006     Document Type: Review

References (50)

1. CD36 and atherosclerosis
2. CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes
3. CD36 is a ditopic glycoprotein with the N-terminal domain implicated in intracellular transport
4. Analysis of CD36 binding domains: Ligand specificity controlled by dephosphorylation of an ectodomain
5. A platelet membrane glycoprotein (GP) deficiency in healthy blood donors: Naka- platelets lack detectable GPIV (CD36)
6. Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells
7. A Drosophila gene encoding an epithelial membrane protein with homology to CD36/LIMP 11
8. Lysosomal integral membrane protein 11 binds thrombospondin-1. Structure-function homology with the cell adhesion molecule CD36 defines a conserved recognition motif
9. Identification of a CD36-related thrombospondin 1-binding domain in HIV-1 envelope glycoprotein gp 120: Relationship to HIV-1-specific inhibitory factors in human saliva
10. Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: Implications for human disease
11. Biochemical isolation of a membrane microdomain from resting platelets highly enriched in the plasma membrane glycoprotein CD36
12. High density lipoprotein prevents oxidized low density lipoprotein-induced inhibition of endothelial nitric oxide synthase localization and activation in caveolae
13. Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase
14. CD36 is a receptor for oxidized low density lipoprotein
15. Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
16. Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species
17. Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice
18. Macrophage vitronectin receptor, CD36, and thrombospondin cooperate ill recognition of neutrophils undergoing programmed cell death
19. Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: Implications with respect to macrophage recognition of apoptotic cells
20. Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: Evidence that oxidation specific epitopes mediate macrophage recognition
21. CD36 participates in the phagocytosis of rod outer segments by retinal pigment epithelium
22. Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
23. The other side of scavenger receptors: Pattern recognition for host defense
24. Molecular basis of sequestration in severe and uncomplicated Plasmodium, falciparum malaria: Differential adhesion of infected erythrogles to CD36 md ICAM-1
25. Malaria susceptibility and CD36 mutation
26. Nonopsonic monocyte/macrophage phagocytosis of plasmodium falciparum-parasitized erythrocytes: A role for CD36 in malarial clearance
27. Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells
28. Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36
29. Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin
30. A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism
31. Identification of Cd36(Fat) as an insulin-resistance gene causing detective fatty acid and glucose metabolism in hypertensive rats
32. Absent myocardial iodine-123-BM1PP uptake and placelet/monocyte CD36 deficiency
33. A tumor suppressor-dependent inhibitor of anglo-genesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
34. CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells
35. Histidine rich glycoprotein inhibits the antiangiogenic effect of thrombospondin-1
36. Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1
37. Isolation of a somatic cell mutant resistant to the induction of apoptosis by oxidized low density lipoprotein
38. Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouse's tale
39. Scavenger receptor class B type is a multiligand HDL receptor that influences diverse physiologic systems
40. Identification of scavenger receptor SR-Bl as a high density lipoprotein receptor
41. Regulared expression of CD36 during monocyte-to-macrophage differentiation: Potential role of CD36 in foam cell formation
42. Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma
43. Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma
44. Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR gamma
45. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
46. Interleukin-4-dependent production of PPARgamma ligands in macrophages by 12/15-lipoxygenase
47. Lewis A. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis
48. Regulation of FAT/CD36 gene expression: Further evidence in support of a role of the protein in Fatty acid binding/transport
49. Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice