Elevated C-reactive protein and long-term mortality after ischaemic stroke relationship with markers of endothelial cell and platelet activation

Stroke

Volumn 40, Issue 3, 2009, Pages 977-979

  Shantikumar, Saran ^a   Grant, Peter J ^a   Catto, Andrew J ^a   Bamford, John M ^b   Carter, Angela M ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS GENERAL INFIRMARY   (United Kingdom)

Author keywords

C reactive protein; Cerebral infarction; Endothelial cell dysfunction; Mortality; Platelet activation

Indexed keywords

ALBUMIN; BETA THROMBOGLOBULIN; C REACTIVE PROTEIN; COMPLEMENT COMPONENT C3; CREATININE; VON WILLEBRAND FACTOR; BIOLOGICAL MARKER;

ADULT; AGE; AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; CHRONIC INFLAMMATION; CONTROLLED STUDY; DEMOGRAPHY; ENDOTHELIAL DYSFUNCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HEART ATRIUM FIBRILLATION; HUMAN; HUMAN TISSUE; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; RISK FACTOR; STATISTICAL ANALYSIS; STROKE; SURVIVOR; THROMBOCYTE ACTIVATION; BRAIN ISCHEMIA; COHORT ANALYSIS; ENDOTHELIUM CELL; LETTER; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PREDICTION AND FORECASTING; REGRESSION ANALYSIS; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BRAIN ISCHEMIA; C-REACTIVE PROTEIN; COHORT STUDIES; COMPLEMENT C3; ENDOTHELIAL CELLS; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; PLATELET ACTIVATION; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; RISK FACTORS; STROKE; TREATMENT OUTCOME;

EID: 62449089772     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.108.525105     Document Type: Article

References (8)

1. Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation. 2003;107:363-369.
2. Muir KW, Weir CJ, Alwan W, Squire IB, Lees KR. C-reactive protein and outcome after ischemic stroke. Stroke. 1999;30:981-985.
3. Di Napoli M, Papa F, Bocola V. C-reactive protein in ischemic stroke: an independent prognostic factor. Stroke. 2001;32:917-924.
4. Elkind MS, Tai W, Coates K, Paik MC, Sacco RL. High-sensitivity C-reactive protein, lipoprotein-associated phospholipase A2, and outcome after ischemic stroke. Arch Intern Med. 2006;166:2073-2080.
5. Carter AM. Inflammation, thrombosis and acute coronary syndromes. Diab Vasc Dis Res. 2005;2:113-121.
6. Carter AM, Catto AJ, Mansfield MW, Bamford JM, Grant PJ. Predictive variables for mortality after acute ischemic stroke. Stroke. 2007;38: 1873-1880.
7. Bisoendial RJ, Kastelein JJ, Levels JH, Zwaginga JJ, van den Bogaard B, Reitsma PH, Meijers JC, Hartman D, Levi M, Stroes ES. Activation of inflammation and coagulation after infusion of C-reactive protein in humans. Circ Res. 2005;96:714-716.
8. Bova IY, Bornstein NM, Korczyn AD. Acute infection as a risk factor for ischemic stroke. Stroke. 1996;27:2204-2206.