Mycobacterium smegmatis expressing a chimeric protein MPT64-Proteolipid Protein (PLP) 139-151 reorganizes the PLP-specific T cell repertoire favoring a CD8-mediated response and induces a relapsing experimental autoimmune encephalomyelitis

Journal of Immunology

Volumn 184, Issue 1, 2010, Pages 222-235

  Nicolò, Chiara ^a   Sali, Michela ^a   Di Sante, Gabriele ^a   Geloso, Maria Concetta ^a   Signori, Emanuela ^b,c   Penitente, Romina ^a   Uniyal, Shashi ^e   Rinaldi, Monica ^c   Ingrosso, Loredana ^d   Fazio, Vito Michele ^b   Chan, Bosco M C ^e   Delogu, Giovanni ^a   Ria, Francesco ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^c CNR   (Italy)

^d ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CHIMERIC PROTEIN; EPITOPE; PROTEOLIPID PROTEIN; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; HYBRID PROTEIN; MPB64 PROTEIN, MYCOBACTERIUM; PEPTIDE FRAGMENT; PROTEOLIPID PROTEIN 139 151; PROTEOLIPID PROTEIN 139-151;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL MODEL; ANTIBODY AFFINITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CROSS REACTION; DEMYELINATION; DISEASE COURSE; DISEASE SEVERITY; ELECTROPORATION; EMBRYO; FEMALE; HISTOLOGY; IMMUNIZATION; LYMPH NODE; MOUSE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SPLEEN; T LYMPHOCYTE; ANIMAL; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PATHOLOGY;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; LYMPHOCYTE ACTIVATION; MICE; MYCOBACTERIUM SMEGMATIS; MYELIN PROTEOLIPID PROTEIN; PEPTIDE FRAGMENTS; RECOMBINANT FUSION PROTEINS;

EID: 73949112939     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0804263     Document Type: Article

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