Infectious causes of multiple sclerosis

Lancet Neurology

Volumn 4, Issue 3, 2005, Pages 195-202

  Gilden, Donald H ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; OLIGOCLONAL BAND; VIRUS ANTIGEN;

BRAIN; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CHLAMYDOPHILA PNEUMONIAE; CLINICAL FEATURE; CORONAVIRUS; DEMYELINATING DISEASE; DEMYELINATION; EPSTEIN BARR VIRUS; GENE AMPLIFICATION; GENE MUTATION; HERPES VIRUS; HUMAN; HUMAN HERPESVIRUS 6; INFECTION; INFLAMMATION; JC VIRUS; MEASLES VIRUS; MOLECULAR DYNAMICS; MONOZYGOTIC TWINS; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; RETROVIRUS; REVIEW; VIRUS; WHITE MATTER;

EID: 13944253325     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(05)70023-5     Document Type: Review

References (78)

1. Lumsden CE. The immunogenesis of the multiple sclerosis plaque. Brain Res. 28:1971;365-390
2. Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: pathology of the newly formed lesion. Ann Neurol. 55:2004;458-468
3. Lassmann H, Raine CS, Antel J, Prineas JW. Immunopathology of multiple sclerosis: report on an international meeting held at the Institute of Neurology of the University of Vienna. J Neuroimmunol. 86:1998;213-217
4. Bouteille M, Fontaine C, Vedrenne C, Delarue J. Sur un cas d'encéphalite subaiguë à inclusions: étude anatomo-clinique et ultrastructurale. Rev Neurol (Paris). 113:1965;454-458
5. Connolly JH, Allen IV, Hurwitz LJ, Miller JD. Measles-virus antibody and antigen in subacute sclerosing panencephalitis. Lancet. 1:1967;542-544
6. Payne FE, Baublis JV, Itabashi HH. Isolation of measles virus from cell cultures of brain from a patient with subacute sclerosing panencephalitis. N Engl J Med. 281:1969;585-616
7. Padgett BL, Walker DL, ZuRhein GM, et al. Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet. 1:1971;1257-1260
8. Buchmeier MJ, Lane TE. Viral-induced neurodegenerative disease. Curr Opin Microbiol. 2:1999;398-402
9. Gilden DH, Devlin ME, Burgoon MP, Owens GP. The search for virus in multiple sclerosis brain. Mult Scler. 2:1996;179-183
10. Vandvik B, Norrby E, Nordal HJ, Derge M. Oligoclonal measles virus-specific IgG antibodies isolated from cerebrospinal fluids, brain extracts, and sera from patients with subacute sclerosing panencephalitis and multiple sclerosis. Scand J Immunol. 5:1976;979-992
11. Porter KG, Sinnamon DG, Gillies RR. Cryptococcus neoformans-specific oligoclonal immunoglobulins in cerebrospinal fluid in cryptococcal meningitis. Lancet. 1:1977;1262
12. Kurtzke JF, Delasnerie-Laupretre N, Wallin MT. Multiple sclerosis in North African migrants to France. Acta Neurol Scand. 98:1998;302-309
13. Hammond SR, English DR, McLeod JG. The age-range of risk of developing multiple sclerosis: evidence from a migrant population in Australia. Brain. 123:2000;968-974
14. Kurtzke JF, Hyllested K. Mutliple sclerosis in the Faroe Islands: I - clinical and epidemiological features. Ann Neurol. 5:1979;6-21
15. Marrie RA. Environmental risk factors in multiple sclerosis aetiology. Lancet Neurol. 3:2004;709-718
16. Nathanson N, Miller A. Epidemiology of multiple sclerosis: critique of the evidence for a viral etiology. Am J Epidemiol. 107:1978;451-461
17. Mackay RP. The familial occurrence of multiple sclerosis and its implications. Ann Intern Med. 33:1950;298-320
18. Spielman RS, Nathanson N. The genetics of susceptibility to multiple sclerosis. Epidemiol Rev. 4:1982;45-65
19. Willer CJ, Dyment DA, Risch NJ, et al. Twin concordance and sibling recurrence rates in multiple sclerosis. Proc Natl Acad Sci USA. 100:2003;12877-12882
20. Sotgiu S, Rosati G, Saana A, et al. Multiple sclerosis complexity in selected populations: the challenge of Sardinia, insular Italy. Eur J Neurol. 9:2002;1-13
21. Dyment DA, Ebers GC, Sadovnick AD. Genetics of multiple sclerosis. Lancet Neurol. 3:2004;104-110
22. Lipton HL, Dal Canto MC. Theiler's virus-induced demyelination: prevention by immunosuppression. Science. 192:1976;62-64
23. Schlitt BP, Felrice M, Jelachich ML, Lipton HL. Apoptotic cells, including macrophages, are prominent in Theiler's virus-induced inflammatory, demyelinating lesions. J Virol. 77:2003;4383-4388
24. Warren KG, Devlin M, Gilden DH, et al. Isolation of herpes simplex virus from human trigeminal ganglia, including ganglia from one patient with multiple sclerosis. Lancet. 2:1977;637-639
25. Warren KG, Brown SM, Wroblewska Z, et al. Isolation of latent herpes simplex virus from the superior cervical and vagus ganglions of humans. N Engl J Med. 298:1978;1068-1069
26. Gilden DH, Wroblewska Z, Chesler M, et al. Experimental panencephalitis induced in suckling mice by parainfluenza type I (6/94) virus II: virologic studies. J Neuropathol Exp Neurol. 35:1976;59-270
27. Wroblewska Z, Gilden DH, Wellish M, et al. Virus-specific intracytoplasmic inclusions in mouse brain produced by a newly isolated strain of Theiler virus: I - virologic and morphologic studies. Lab Invest. 37:1977;595-602
28. ter Meulen V, Koprowski H, Iwasaki Y, et al. Fusion of cultured multiple-sclerosis brain cells with indicator cells: presence of nucleocapsids and virions and isolation of parainfluenza-type virus. Lancet. 2:1972;1-5
29. Rorke LB, Iwasaki Y, Koprowski H, et al. Acute demyelinating disease in a chimpanzee three years after inoculation of brain cells from a patient with MS. Ann Neurol. 5:1979;89-94
30. Wroblewska Z, Gilden DH, Devlin M, et al. Cytomegalovirus isolation from a chimpanzee with acute demyelinating disease after inoculation of MS brain cells. Infect Immun. 25:1979;1008-1015
31. Gilden DH. A search for virus in multiple sclerosis. Hybrid Hybridomics. 21:2002;93-97
32. Weiss RA, Boettiger D, Love DN. Phenotypic mixing between vesicular stomatitis virus and avian RNA tumor viruses. Cold Spring Harbor Symp. 39:1975;913-918
33. Sriram S, Stratton CW, Yao S, et al. Chlamydia pneumoniae infection of the central nervous system in multiple sclerosis. Ann Neurol. 46:1999;6-14
34. Krametter D, Niederwieser G, Berghold A, et al. Chlamydia pneumoniae in multiple sclerosis: humoral immune responses in serum and cerebrospinal fluid and correlation with disease activity marker. Mult Scler. 7:2001;13-18
35. Tsai JC, Gilden DH. Chlamydia pneumoniae and multiple sclerosis: no significant association. Trends Microbiol. 9:2001;152-154
36. Liedtke W, Malessa R, Faustmann PM, Eis-Hubinger AM. Human herpesvirus 6 polymerase chain reaction findings in human immunodeficiency virus associated neurological disease and multiple sclerosis. J Neurovirol. 1:1995;253-258
37. Goldberg SH, Albright AV, Lisak RP, Gonzalez-Scarano F. Polymerase chain reaction analysis of human herpesvirus-6 sequences in the sera and cerebrospinal fluid of patients with multiple sclerosis. J Neurovirol. 5:1999;134-139
38. Berti R, Brennan MB, Soldan SS, et al. Increased detection of serum HHV-6 DNA sequences during multiple sclerosis (MS) exacerbations and correlation with parameters of MS disease progression. J Neurovirol. 8:2002;250-256
39. Gutierrez J, Vergara MJ, Guerrero M, et al. Multiple sclerosis and human herpesvirus 6. Infection. 30:2002;145-149
40. Soldan SS, Berti R, Salem N, et al. Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA. Nat Med. 3:1997;1394-1397
41. Friedman JE, Lyons MJ, Ablashi DV, et al. The association of the human herpesvirus-6 and MS. Mult Scler. 5:1999;355-362
42. Alvarez-Lafuente R, Martin-Estefania C, de Las Heras V, et al. Active human herpesvirus 6 infection in patients with multiple sclerosis. Arch Neurol. 59:2002;929-933
43. Challoner PB, Smith KT, Parker JD, et al. Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc Natl Acad Sci USA. 92:1995;7740-7744
44. Cuomo L, Trivedi P, Cardillo MR, et al. Human herpesvirus 6 infection in neoplastic and normal brain tissue. J Med Virol. 63:2001;45-51
45. Mirandola P, Stefan A, Brambilla E, et al. Absence of human herpes virus 6 and 7 from spinal fluid and serum of multiple sclerosis patients. Neurology. 53:1999;1367-1368
46. Rodriguez Carnero S, Martinez-Vazquez C, Potel Alvarellos C, et al. Lack of human herpesvirus type 6 DNA in CSF by nested PCR among patients with multiple sclerosis. Rev Clin Esp. 202:2002;588-591
47. Nielsen L, Larsen AM, Munk M, Vestergaard BF. Human herpesvirus-6 immunoglobulin G antibodies in patients with multiple sclerosis. Acta Neurol Scan Suppl. 169:1997;76-78
48. Blumberg BM, Mock DJ, Powers JM, et al. The HHV6 paradox: ubiquitous commensal or insidious pathogen? A two-step in situ PCR approach. J Clin Virol. 16:2000;159-178
49. Cermelli C, Bert R, Soldan SS, et al. High frequency of human herpesvirus 6 DNA in multiple sclerosis plaques isolated by aster microdissection. J Infect Dis. 187:2003;1377-1387
50. Wandinger K, Jabs W, Siekhaus A, et al. Association between clinical disease activity and Epstein-Barr virus reactivation in MS. Neurology. 55:2000;178-184
51. Ascherio A, Munch M. Epstein-Barr virus and multiple sclerosis. Epidemiology. 11:2000;220-304
52. Bray PF, Luka J, Bray PF, et al. Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein. Neurology. 42:1992;1798-1804
53. Ascherio A, Gorham KL, Lennette ET, et al. Epstein-Barr virus antibodies and risk of multiple sclerosis: a prospective study. JAMA. 286:2002;3083-3088
54. Lewin LI, Munger KL, Rubertone MV, et al. Multiple sclerosis and Epstein-Barr virus. JAMA. 289:2003;1533-1536
55. Haahr S, Plesner AM, Vestergaard BF, Hollsberg P. A role of late Epstein-Barr virus infection in multiple sclerosis. Acta Neurol Scand. 109:2004;270-275
56. Majid A, Galetta SL, Sweeney CJ, et al. Epstein-Barr virus myeloradiculitis and encephalomyeloradiculitis. Brain. 125:2002;1-7
57. Hilton DA, Love S, Fletcher A, Pringle JH. Absence of Epstein-Barr virus in multiple sclerosis as assessed by in situ hybridisation. J Neurol Neurosurg Psychiatry. 57:1994;975-976
58. Hawkes CH. Is multiple sclerosis a sexually transmitted infection? J Neurol Neurosurg Psychiatry. 73:2002;439-443
59. Jocher R, Rethwilm A, Kappos L, ter Meulen V. Search for retroviral sequences in peripheral blood mononuclear cells and brain tissue of multiple sclerosis patients. J Neurol. 237:1990;352-355
60. Ehrlich GD, Glaser JB, Bryz-Gornia V, et al. Multiple sclerosis, retroviruses, and PCR. Neurology. 41:1991;335-343
61. Perron H, Geny C, Genoulaz O, et al. Antibody to reverse transcriptase of human retroviruses in multiple sclerosis. Acta Neurol Scand. 84:1991;507-513
62. Rozenberg F, Lefebvre S, Lubetzki C, et al. Analysis of retroviral sequences in the spinal form of multiple sclerosis. Ann Neurol. 29:1991;333-336
63. Hackett J Jr, Swanson P, Leahy D, et al. Search for retrovirus in patients with multiple sclerosis. Ann Neurol. 40:1996;805-809
64. Rasmussen HB, Geny C, Deforges L, et al. Expression of endogenous retroviruses in blood mononuclear cells and brain tissue from multiple sclerosis patients. Acta Neurol Scand Suppl. 169:1997;38-44
65. Perron H, Garson JA, Bedin F, et al. Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. Proc Natl Acad Sci USA. 94:1997;7583-7588
66. Murray RS, Brown B, Brain D, Cabirac GF. Detection of coronavirus RNA and antigen in multiple sclerosis brain. Ann Neurol. 31:1992;525-533
67. Stewart JN, Mounir S, Talbot PJ. Human coronavirus gene expression in the brains of multiple sclerosis patients. Virology. 191:1992;502-505
68. Dessau RB, Lisby G, Frederiksen JL. Coronaviruses in brain tissue from patients with multiple sclerosis. Acta Neuropathol (Berl). 101:2001;601-604
69. Boerman RH, Bax JJ, Beekhuis-Brussee JA, et al. JC virus and multiple sclerosis: a refutation? Acta Neurol Scand. 87:1993;353-355
70. Stoner GL, Agostini HT, Ryschkewitsch CF, et al. Characterization of JC virus DNA amplified from urine of chronic progressive multiple sclerosis patients. Mult Scler. 1:1996;193-199
71. Agostini HT, Ryschkewitsch CF, Baumhefner RW, et al. Influence of JC virus coding region genotype on risk of multiple sclerosis and progressive multifocal leukoencephalopathy. J Neurovirol. 6:2000;S101-108
72. Ferrante P, Omodeo-Zorini E, Caldarelli-Stefano R, et al. Detection of JC virus DNA in cerebrospinal fluid from multiple sclerosis patients. Mult Scler. 4:1998;49-54
73. Choo Q-L, Kuo G, Weiner A, et al. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science. 244:1989;359-362
74. H4 germline segments in an acute multiple sclerosis brain. Ann Neurol. 43:1998;236-243
75. Owens GP, Ritchie A, Burgoon MP, et al. Single-cell repertoire analysis demonstrates that clonal expansion is a prominent feature of the B cell response in multiple sclerosis cerebrospinal fluid. J Immunol. 171:2003;2725-2733
76. Smith-Jensen T, Burgoon MP, Anthony J, et al. Comparison of IgG heavy chain sequences in MS and SSPE brains reveals an antigen-driven response. Neurology. 54:2000;1227-1232
77. Haubold K, Owens GP, Kaur P, et al. B-lymphocyte and plasma cell clonal expansion in monosymptomatic optic neuritis cerebrospinal fluid. Ann Neurol. 56:2004;97-107
78. + cell antibody repertoires in the cerebrospinal fluid of patients with multiple sclerosis. J Immunol. 173:2004;649-656