Alteration at a single amino acid residue in the T cell receptor α chain complementarity determining region 2 changes the differentiation of naive CD4 T cells in response to antigen from T helper cell type 1 (Th1) to Th2

Journal of Experimental Medicine

Volumn 191, Issue 12, 2000, Pages 2065-2073

  Blander, J Magarian ^a   Sant'Angelo, Derek B ^b   Bottomly, Kim ^a   Janeway Jr , Charles A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

Author keywords

Interferon type II; Interleukin 4; Mice; Peptides; Transgenic

Indexed keywords

INTERLEUKIN 4; LEUCINE; SERINE; T LYMPHOCYTE RECEPTOR ALPHA CHAIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; GENES, T-CELL RECEPTOR ALPHA; IMMUNITY, CELLULAR; INTERFERON TYPE II; INTERLEUKIN-4; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MUTATION; PEPTIDES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; TH1 CELLS; TH2 CELLS;

EID: 0034686578     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.12.2065     Document Type: Article

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