Extracellular Nucleotides and Renal Function

Seldin and Giebisch's The Kidney

Volumn , Issue , 2008, Pages 425-442

  Bailey, Matthew A ^a   Shirley, David G ^a   King, Brian F ^a   Burnstock, Geoffrey ^a   Unwin, Robert J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 73849096230     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012088488-9.50020-6     Document Type: Chapter

References (167)

1. Abbracchio M.P., Burnstock G. Purinergic signalling: pathophysiological roles. Jpn J Pharmacol 1998, 78:113-145.
2. Abbracchio M.P., Boeynaems J.M., Barnard E.A., et al. Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family. Trends Pharmacol Sci 1903, 24:52-55.
3. Agboh K.C., Webb T.E., Evans R.J., et al. Functional characterization of a P2X receptor from Schistosoma mansoni. J Biol Chem 2004, 279:41650-41657.
4. Anderson R.J., Breckon R., Dixon B.S. ATP receptor regulation of adenylate cyclase and protein kinase C activity in cultured renal LLC-PK1 cells. J Clin Invest 1991, 87:1732-1738.
5. + exchanger NHE3 activity in A6-NHE3 transfectants by a cAMP/PKA-dependent mechanism. J Membr Biol 2002, 188:249-259.
6. Bailey M.A., Hillman K.A., Unwin R.J. P2 receptors in the kidney. J Auton Nerv Syst 2000, 81:264-270.
7. Bailey M.A., Imbert-Teboul M., Turner C., et al. Axial distribution and characterization of basolateral P2Y receptors along the rat renal tubule. Kidney Int 1900, 58:1893-1901.
8. Bailey M.A., Imbert-Teboul M., Turner C., et al. Evidence for basolateral P2Y6 receptors along the rat proximal tubule: functional and molecular characterization. J Am Soc Nephrol 2001, 12:1640-1647.
9. Bailey M.A., Turner C.M., Hus-Citharel A., et al. P2Y receptors present in the native and isolated rat glomerulus. Nephron Physiol 2004, 96:p79-p90.
10. Bailey M.A. Inhibition of bicarbonate reabsorption in the rat proximal tubule by activation of luminal P2Y1 receptors. Am J Physiol Renal Physiol 2004, 287:F789-F796.
11. Barrera N.P., Ormond S.J., Henderson R.M., et al. Atomic force microscopy imaging demonstrates that P2X2 receptors are trimers but that P2X6 receptor subunits do not oligomerize. J Biol Chem 2005, 280:10759-10765.
12. Beliveau R., Brunette M.G., Strevey J. Characterization of phosphate binding by alkaline phosphatase in rat kidney brush border membrane. Pflügers Arch 1983, 398:227-232.
13. Bell P.D., Lapointe J.Y., Sabirov R., et al. Macula densa cell signaling involves ATP release through a maxi anion channel. Proc Natl Acad Sci U S A 2003, 100:4322-4327.
14. Bender E., Buist A., Jurzak M., et al. Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc Natl Acad Sci U S A 2002, 99:8573-8578.
15. Bogdanov Y., Rubino A., Burnstock G. Characterisation of subtypes of the P2X and P2Y families of ATP receptors in the foetal human heart. Life Sci 1998, 62:697-703.
16. Bouyer P., Paulais M., Cougnon M., et al. Extracellular ATP raises cytosolic calcium and activates basolateral chloride conductance in Necturus proximal tubule. J Physiol 1998, 510:535-548.
17. 2+ mobilization by a nucleotide receptor in glomerular endothelial cells. Am J Physiol 1994, 266:F210-F217.
18. Brown S.G., Kim Y.C., Kim S.A., et al. Actions of a series of PPADS analogs at P2X1 and P2X3 receptors. Drug Devel Res 2001, 53:281-291.
19. Buell G., Collo G., Rassendren F. P2X receptors: an emerging channel family. Eur J Neurosci 1996, 8:2221-2228.
20. Burnstock G. Purinergic nerves. Pharmacol Rev 1972, 24:509-581.
21. Burnstock G., King B.F. Numbering of cloned P2 receptors. Drug Devel Res 1996, 38:67-71.
22. Castrop H., Huang Y., Hashimoto S., et al. Impairment of tubuloglomerular feedback regulation of GFR in ecto-5'-nucleotidase/CD73-deficient mice. J Clin Invest 2004, 114:634-642.
23. Cejka J.C., Le Maout S., Bidet M., et al. Activation of calcium influx by ATP and store depletion in primary cultures of renal proximal cells. Pflügers Arch 1994, 427:33-41.
24. Cha S.H., Jung K.Y., Endou H. Effect of P2Y-purinoceptor stimulation on renal gluconeogenesis in rats. Biochem Biophys Res Commun 1995, 211:454-461.
25. 2 receptors by conformational constraints of an ADP analog. Am J Physiol 1998, 274:F1006-F1014.
26. Chambers J.K., Macdonald L.E., Sarau H.M., et al. A G protein-coupled receptor for UDP-glucose. J Biol Chem 2000, 275:10767-10771.
27. Chan C.M., Unwin R.J., Burnstock G. Potential functional roles of extracellular ATP in kidney and urinary tract. Exp Nephrol 1998, 6:200-207.
28. 1 purinoceptors by autoradiography and immunohistochemistry in rat kidneys. Am J Physiol 1998, 274:F799-F804.
29. 13 receptors by conformational con ADP analog. J Pharmacol Exp Ther 2004, 311:1038-1043.
30. Churchill P.C., Ellis V.R. Pharmacological characterization of the renovascular P2 purinergic receptors. J Pharmacol Exp Ther 1993, 265:334-338.
31. Churchill P.C., Ellis V.R. Purinergic P2y receptors stimulate renin secretion by rat renal cortical slices. J Pharmacol Exp Ther 1993, 266:160-163.
32. 11 receptor. Br J Pharmacol 1999, 128:1199-1206.
33. Costanzi S., Mamedova L., Gao Z.G., et al. Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling. J Med Chem 2004, 47:5393-5404.
34. + absorption in M-1 mouse cortical collecting duct cells. J Physiol 2000, 524:77-90. Pt 1.
35. 2+ uptake in MDCT cells via P2X purinoceptors. Am J Physiol Renal Physiol 2001, 281:F833-F840.
36. Deetjen P., Thomas J., Lehrmann H., et al. The luminal P2Y receptor in the isolated perfused mouse cortical collecting duct. J Am Soc Nephrol 2000, 11:1798-1806.
37. Defer N., Best-Belpomme M., Hanoune J. Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase. Am J Physiol Renal Physiol 2000, 279:F400-F416.
38. + flux in proximal tubules through NO release. Am J Physiol Renal Physiol 2001, 280:F239-F243.
39. Dockrell M.E., Noor M.I, James A.F., et al. Heterogeneous calcium responses to extracellular ATP in cultured rat renal tubule cells. Clin Chim Acta 2001, 303:133-138.
40. Drury A.N., Szent-Gyorgyi A. The physiological activity of adenine compounds with special reference to their action upon the mammalian heart. J Physiol 1929, 68:213-237.
41. Edgecombe M., Craddock H.S., Smith D.C., et al. Diadenosine polyphosphate-stimulated gluconeogenesis in isolated rat proximal tubules. Biochem J 1997, 323:451-456.
42. Edwards R.M. Basolateral, but not apical, ATP inhibits vasopressin action in rat inner medullary collecting duct. Eur J Pharmacol 2002, 438:179-181.
43. Ekberg K., Landau B.R., Wajngot A., et al. Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fasting. Diabetes 1999, 48:292-298.
44. Filipovic D.M., Adebanjo O.A., Zaidi M., et al. Functional and molecular evidence for P2X receptors in LLC-PK1 cells. Am J Physiol 1998, 274:F1070-F1077.
45. Fischer K.G., Saueressig U., Jacobshagen C., et al. Extracellular nucleotides regulate cellular functions of podocytes in culture. Am J Physiol Renal Physiol 2001, 281:F1075-F1081.
46. Fredriksson R., Lagerstrom M.C., Lundin L.G., et al. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol 1903, 63:1256-1272.
47. Freeman K., Tsui P., Moore D., et al. Cloning, pharmacology, and tissue distribution of G-proteincoupled receptor GPR105 (KIAA0001) rodent orthologs. Genomics 2001, 78:124-128.
48. Friedrich F., Weiss H., Paulmichl M., et al. Further analysis of ATP-mediated activation of K channels in renal epithelioid Madin Darby canine kidney (MDCK) cells. Pflugers Arch 1991, 418:551-555.
49. Gandhi R., Le Hir M., Kaissling B. Immunolocalization of ecto-5'-nucleotidase in the kidney by a monoclonal antibody. Histochemistry 1990, 95:165-174.
50. Gorelik J., Zhang Y., Sanchez D., et al. Aldosterone acts via an ATP autocrine/paracrine system: the Edelman ATP hypothesis revisited. Proc Natl Acad Sci U S A 2005, 102:15000-15005.
51. Guder W.G., Ross B.D. Enzyme distribution along the nephron. Kidney Int 1984, 26:101-111.
52. Guerra L., Favia M., Fanelli T., et al. Stimulation of Xenopus P2Y1 receptor activates CFTR in A6 cells. Pflugers Arch 1904, 449:66-75.
53. Hafting T., Sand O. Purinergic activation of BK channels in clonal kidney cells (Vero cells). Acta Physiol Scand 2000, 170:99-109.
54. + exchanger regulatory factor family of PDZ proteins. Proc Natl Acad Sci U S A 1998, 95:8496-8501.
55. Harada H., Chan C.M., Loesch A., et al. Induction of proliferation and apoptotic cell death via P2Y and P2X receptors, respectively, in rat glomerular mesangial cells. Kidney Int 1900, 57:949-958.
56. Harahap A.R., Goding J.W. Distribution of the murine plasma cell antigen PC-1 in nonlymphoid tissues. J Immunol 1988, 141:2317-2320.
57. Hasegawa G., Nakano K., Sawada M., et al. Possible role of tumor necrosis factor and interleukin-1 in the development of diabetic nephropathy. Kidney Int 1991, 40:1007-1012.
58. Hillman K.A., Johnson T.M., Winyard P.J., et al. P2X7 receptors are expressed during mouse nephrogenesis and in collecting duct cysts of the cpk/cpk mouse. Exp Nephrol 2002, 10:34-42.
59. Hillman K.A., Woolf A.S., Johnson T.M., et al. The P2X7 ATP receptor modulates renal cyst development in vitro. Biochem Biophys Res Commun 2004, 322:434.439.
60. 7 receptor in the kidney: a matter of life of death?. Nephron Exp Nephrol 2005, 101:e24-e30.
61. Hooper K.M., Unwin R.J., Sutters M. The isolated C-terminus of polycystin-1 promotes increased ATP-stimulated chloride secretion in a collecting duct cell line. Clin Sci 2003, 104:217-221.
62. Hoyle C.H.V., Hilderman R., Pintor J., et al. Diadenosine polyphosphates as extracellular signaling molecules. Drug Devel Res 2001, 52:260-273.
63. 1 receptors. Eur J Pharmacol 2003, 470:1-7.
64. Humes H.D., Cieslinski D.A. Adenosine triphosphate stimulates thymidine incorporation but does not promote cell growth in primary cultures of renal proximal tubule cells. Ren Physiol Biochem 1991, 14:253-258.
65. Huwiler A., Wartmann M., van den Bosch H., et al. Extracellular nucleotides activate the p38-stress-activated protein kinase cascade in glomerular mesangial cells. Br J Pharmacol 2000, 129:612-618.
66. Inscho E.W., Ohishi K., Navar L.G. Effects of ATP on pre- and postglomerular juxtamedullary microvasculature. Am J Physiol Renal Physiol 1992, 263:F886-F893.
67. Inscho E.W., Cook A.K., Mui V., et al. Direct assesment of renal microvascular responses to P2-purinoceptor agonists. Am J Physiol Renal Physiol 1998, 274:F718-F727.
68. Inscho E.W. P2 receptors in regulation of renal microvascular function. Am J Physiol Renal Physiol 2001, 280:F927-F944.
69. Inscho E.W. Renal microvascular effects of P2 receptor stimulation. Clin Exp Pharmacol Physiol 1901, 28:332-339.
70. 1 receptors in renal microvascular autoregulatory behavior. J Clin Invest 2003, 112:1895-1905.
71. Inscho E.W., Cook A.K., Imig J.D., et al. Renal autoregulation in P2X1 knockout mice. Acta Physiol Scand 2004, 181:445-453.
72. Ishikawa S., Higashiyama M., Kusaka I., et al. Extracellular ATP promotes cellular growth of renal inner medullary collecting duct cells mediated via P2u receptors. Nephron 1997, 76:208-214.
73. Jacobson K.A., Costanzi S., Ohno M., et al. Molecular recognition at purine and pyrimidine nucleotide (P2) receptors. Curr Top Med Chem 2004, 4:805-819.
74. Jankowski M., Szczepanska-Konkel M., Kalinowski L., et al. Bidirectional action of extracellular ATP on intracapillary volume of isolated rat renal glomeruli. J Physiol Pharmacol 2000, 51:491-496.
75. Jankowski M., Szczepanska-Konkel M., Kalinowski L., et al. Cyclic GMP-dependent relaxation of isolated rat renal glomeruli induced by extracellular ATP. J Physiol 2001, 530:123-130.
76. Jankowski M., Szczepanska-Konkel K., Kalinowski L., et al. Involvement of Rho-kinase in P2Y-receptor-mediated contraction of renal glomeruli. Biochem Biophys Res Commun 2003, 302:855-859.
77. Jankowski V., Tolle M., Vanholder R., et al. Uridine adenosine tetraphosphate: a novel endothelium-derived vasoconstrictive factor. Nat Med 2005, 11:223-227.
78. Janssens R., Paindavoine P., Parmentier M., et al. Human P2Y2 receptor polymorphism: identification and pharmacological characterization of two allelic variants. Br J Pharmacol 1999, 127:709-716.
79. 2+ is not required. Am J Physiol 1997, 272:C1169-C1177.
80. Kalinowski L., Dobrucki L.W., Szczepanska-Konkel M., et al. Third-generation beta-blockers stimulate nitric oxide release from endothelial cells through ATP efflux: a novel mechanism for antihypertensive action. Circulation 2003, 107:2747-2752.
81. Kenakin T. Efficacy at G-protein-coupled receptors. Nat Rev Drug Discov 2002, 1:103-110.
82. 1 receptors. Br J Pharmacol 1999, 128:981-988.
83. Kishore B.K., Chou C.L., Knepper M.A. Extracellular nucleotide receptor inhibits AVPstimulated water permeability in inner medullary collecting duct. Am J Physiol 1995, 269:F863-F869.
84. Kishore B.K., Ginns S.M., Krane C.M., et al. Cellular localization of P2Y2 purinoceptor in rat renal inner medulla and lung. Am J Physiol Renal Physiol 2000, 278:F43-F51.
85. Kishore B.K., Krane C.M., Miller R.L., et al. P2Y2 receptor mRNA and protein expression is altered in inner medullas of hydrated and dehydrated rats: relevance to AVP-independent regulation of IMCD functi. Am J Physiol Renal Physiol 2005, 288:F1164-F1172.
86. Kishore B.K., Isaac J., Fausther M., et al. Expression of NTPDase1 and NTPDase2 in murine kidney: relevance to regulation of P2 receptor signaling. Am J Physiol Renal Physiol 2005, 288:F1032-F1043.
87. Kluth D.C., Rees A.J. New approaches to modify glomerular inflammation. J Nephrol 1999, 12:66-75.
88. Komlosi P., Peti-Peterdi J., Fuson A.L., et al. Macula densa basolateral ATP release is regulated by luminal [NaCl] and dietary salt intake. Am J Physiol Renal Physiol 2004, 286:F1054-F1058.
89. 7 receptor alters leukocyte function and attenuates an inflammatory response. J Immunol 2002, 168:6436-6445.
90. Lazarowski E.R., Boucher R.C. UTP as an extracellular signaling molecule. News Physiol Sci 2001, 16:1-5.
91. Lazarowski E.R., Boucher R.C., Harden T.K. Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules. Mol Pharmacol 2003, 64:785-795.
92. Lazarowski E.R., Shea D.A., Boucher R.C., et al. Release of cellular UDP-glucose as a potential extracellular signaling molecule. Mol Pharmacol 2003, 63:1190-1197.
93. + absorption in isolated perfused mouse CCD. J Am Soc Nephrol 2002, 13:10-18.
94. Leipziger J. Control of epithelial transport via luminal P2 receptors. Am J Physiol Renal Physiol 2003, 284:F419-F432.
95. 2 receptor in isolated perfused mouse medullary thick ascending limb. J Am Soc Nephrol 2004, 15:A42. (Abstract).
96. Leipziger J., Bailey M.A., Unwin R.J. Purinergic receptors in the kidney. Extracellular Nucleotides and Nucleosides. Release, Receptors, and Physiological and Pathophysiological Effects 2003, 369-394. New York Academic Press. E.M. Schwiebert (Ed.).
97. Liu R., Bell P.D., Peti-Peterdi J., et al. Purinergic receptor signaling at the basolateral membrane of macula densa cells. J Am Soc Nephrol 2002, 13:1145-1151.
98. Lu M., MacGregor G.G., Wang W., et al. Extracellular ATP inhibits the small-conductance K channel on the apical membrane of the cortical collecting duct from mouse kidney. J Gen Physiol 2000, 116:299-310.
99. Ma H.P., Li L., Zhou Z.H., et al. ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells. Am J Physiol Renal Physiol 2002, 282:F501-F505.
100. Majid D.S., Navar L.G. Suppression of blood flow autoregulation plateau during nitric oxide blockade in canine kidney. Am J Physiol 1992, 262:F40-F46.
101. 6 nucleotide receptors. Biochem Pharmacol 2004, 67:1763-1770.
102. McCoy D.E., Taylor A.L., Kudlow B.A., et al. Nucleotides regulate NaCl transport in mIMCD-K2 cells via P2X and P2Y purinergic receptors. Am J Physiol 1999, 277:F552-F559.
103. Mitchell K.D., Navar L.G. Modulation of tubuloglomerular feedback responsiveness by extracellular ATP. Am J Physiol Renal Physiol 1993, 264:F458-F466.
104. Mo J., Fisher M.J. Uridine nucleotide-induced stimulation of gluconeogenesis in isolated rat proximal tubules. Naunyn Schmiedebergs Arch Pharmacol 2002, 366:151-157.
105. Modlinger P.S., Welch W.J. Adenosine A1 receptor antagonists and the kidney. Curr Opin Nephrol Hypertens 2003, 12:497-502.
106. Needleman P., Minkes M.S., Douglas J.R. Stimulation of prostaglandin biosynthesis by adenine nucleotides. Profile of prostaglandin release by perfused organs. Circ Res 1974, 34:455-460.
107. Niemir Z.I., Stein H., Dworacki G., et al. Podocytes are the major source of IL-1 alpha and IL-1 beta in human glomerulonephritides. Kidney Int 1997, 52:393-403.
108. Nishiyama A., Majid D.S., Walker M., et al. Renal interstitial ATP responses to changes in arterial pressure during alterations in tubuloglomerular feedback activity. Hypertension 2001, 37:753-759.
109. Nishiyama A., Navar L.G. ATP mediates tubuloglomerular feedback. Am J Physiol Regul Integr Comp Physiol 2002, 283:R273-R275. discussion R278-R279.
110. North R.A. Molecular physiology of P2X receptors. Physiol Rev 2002, 82:1013-1067.
111. Novak I. ATP as a signaling molecule: the exocrine focus. News Physiol Sci 2003, 18:12-17.
112. Oberhauser V., Vonend O., Rump L.C. Neuropeptide Y and ATP interact to control renovascular resistance in the rat. J Am Soc Nephrol 1999, 10:1179-1185.
113. Paulais M., Bandouin-Legros M., Teulon J. Extracellular ATP and UTP trigger calcium entry in mouse cortical thick ascending limb. Am J Physiol 1995, 268:F496-F502.
114. Pavenstadt H., Gloy J., Leipziger J., et al. Effect of extracellular ATP on contraction, cytosolic calcium activity, membrane voltage and ion currents of rat mesangial cells in primary culture. Br J Pharmacol 1993, 109:953-959.
115. Praetorius H.A., Frøkiaer J., Leipziger J. Transepithelial pressure pulses induce nucleotide release in polarized MDCK cells. Am J Physiol Renal Physiol 2005, 288:F133-F141.
116. Ralevic V., Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev 1998, 50:413-492.
117. Ren Y., Carretero O.A., Garvin J.L. Role of mesangial cells and gap junctions in tubuloglomerular feedback. Kidney Int 2002, 62:525-531.
118. Ren Y., Garvin J.L., Liu R., et al. Role of macula densa adenosine triphosphate (ATP) in tubuloglomerular feedback. Kidney Int 1904, 66:1479-1485.
119. Roberts J.A., Evans R.J. ATP binding at human P2X1 receptors. Contribution of aromatic and basic amino acids revealed using mutagenesis and partial agonists. J Biol Chem 2004, 279:9043-9055.
120. Rost S., Daniel C., Schulze-Lohoff E., et al. P2 receptor antagonist PPADS inhibits mesangial cell proliferation in experimental mesangial proliferative glomerulonephritis. Kidney Int 2002, 62:1659-1671.
121. Rouse D., Leite M., Suki W.N. ATP inhibits the hydrosmotic effect of AVP in rabbit CCT: evidence for a nucleotide P2u receptor. Am J Physiol 1994, 267:F289-F295.
122. 1 receptor to phospholipase C. Br J Pharmacol 1997, 122:1021-1024.
123. Schnermann J., Castrop H., Hansen P. Adenosine as a paracrine regulator of nephron function. J Physiol 2004, 560P:SA16. (Abstract).
124. Schnermann J.B., Traynor T., Yang T., et al. Absence of tubuloglomerular feedback responses in AT1A receptor-deficient mice. Am J Physiol 1997, 273:F315-F320.
125. Schulte E.A., Hohendahl A., Stegemann H., et al. Natriuretic peptides and diadenosine polyphosphates modulate pH regulation of rat mesangial cells. Cell Physiol Biochem 1999, 9:310-322.
126. Schulze-Lohoff E., Bitzer M., Schagerl S., et al. Regulation of mesangial cell proliferation by purinergic ligands. Exp Nephrol 1994, 2:136.
127. 7 receptors. Am J Physiol 1998, 275:F962-F971.
128. Schwartz D.D., Malik K.U. Renal periarterial nerve stimulation-induced vasoconstriction at low frequencies is primarily due to release of a purinergic transmitter in the rat. J Pharmacol Exp Ther 1989, 250:764-771.
129. Schweda F., Wagner C., Kramer B.K., et al. Preserved macula densa-dependent renin secretion in A1 adenosine receptor knockout mice. Am J Physiol Renal Physiol 2003, 284:F770-F777.
130. Schwiebert E.M., Kishore B.K. Extracellular nucleotide signaling along the renal epithelium. Am J Physiol Renal Physiol 2001, 280:F945-F963.
131. Schwiebert E.M., Wallace D.P., Braunstein G.M., et al. Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys. Am J Physiol Renal Physiol 2002, 282:F763-F775.
132. Shaver S.R., Rideout J.L., Pendergast W., et al. Structure-activity relationships of dinucleotides: potent and selective agonists of P2Y receptors. Purinergic Signalling 2005, 1:183-191.
133. Shirley D.G., Bailey M.A., Unwin R.J. In vivo stimulation of apical P2 receptors in collecting ducts: evidence for inhibition of sodium reabsorption. Am J Physiol Renal Physiol 2005, 288:F1243-F1248.
134. 4 receptor channels. J Gen Physiol 2005, 125:347-359.
135. Silva G., Beierwaltes W.H., Garvin J.L. Extracellular ATP stimulates NO production in rat thick ascending limb. Hypertension 2006, 47:563-567.
136. Simmons N.L. Identification of a purine (P2) receptor linked to ion transport in a cultured renal (MDCK) epithelium. Br J Pharmacol 1981, 73:379-384.
137. Solini A., Iacobini C., Ricci C., et al. Purinergic modulation of mesangial extracellular matrix production: role in diabetic and other glomerular diseases. Kidney Int 2005, 67:875-885.
138. Sun D., Samuelson L.C., Yang T., et al. Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci U S A 2001, 98:9983-9988.
139. 2 release by IMCD. Am J Physiol Renal Physiol 2005, 289:F768-F776.
140. Takeda M., Kobayashi M., Endou H. Establishment of a mouse clonal early proximal tubule cell line and outer medullary collecting duct cells expressing P2 purinoceptors. Biochem Mol Biol Int 1998, 44:657-664.
141. 2 receptor-mediated inhibition of amiloridesensitive short circuit current in M-1 mouse cortical collecting duct cells. J Membr Biol 2001, 183:115-124.
142. Turner C.M., Vonend O., Chan C., et al. The pattern of distribution of selected ATP-sensitive P2 receptor subtypes in normal rat kidney:an immunohistological study. Cells Tissues Organs 2003, 175:105-117.
143. Turner C.M., Ramesh B., Srai S.K., et al. Altered ATP-sensitive P2 receptor subtype expression in the Han:SPRD cy/+ rat, a model of autosomal dominant polycystic kidney disease. Cells Tissues Organs 2004, 178:168-179.
144. 7 receptor in experimental and human glomerulonephritis. Nephrol Dial Transplant 2007, 22:386-395.
145. Unwin R.J., Bailey M.A., Burnstock G. Purinergic signaling along the renal tubule: the current state of play. News Physiol Sci 2003, 18:237-241.
146. van der Giet M., Westhoff T., Cinkilic O., et al. The critical role of adenosine and guanosine in the affinity of dinucleoside polyphosphates to P2X-receptors in the isolated perfused rat kidney. Br J Pharmacol 2001, 132:467-474.
147. Vekaria R.M. Vesicular storage and release of ATP in a rat proximal tubule cell line. J Physiol 1904, 560P:C17. (Abstract).
148. Vekaria R.M., Shirley D.G., Sévigny J., et al. Immunolocalization of ectonucleotidases along the rat nephron. Am J Physiol Renal Physiol 2006, 290:F550-F560.
149. Vekaria R.M., Unwin R.J., Shirley D.G. Intraluminal ATP concentrations in rat renal tubules. J Am Soc Nephrol 2006, 17:1841-1847.
150. 7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1 beta release. J Immunol 2003, 170:5728-5738.
151. 2/3 receptors. Mol Pharmacol 1998, 53:969-973.
152. Vonend O., Turner C.M., Chan C.M., et al. Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models. Kidney Int 2004, 66:157-166.
153. 4 receptor. J Neurochem 1998, 71:1348-1357.
154. 2 receptor by neurotransmitters and related substances. Br J Pharmacol 1997, 120:221-224.
155. 2+ entry. Am J Physiol Renal Physiol 2003, 285:F1168-F1178.
156. + channels and P2X receptors. J Am Soc Nephrol 2005, 16:2586-2597.
157. Wildman S.S., Peppiatt C.M., Boone M., et al. Possible role of apical P2 receptors in modulating aquaporin-2-mediated water reabsorption in the collecting duct. Proc Physiol Soc 2006, 2:PC4. (Abstract).
158. 7 receptor C terminus. J Biol Chem 2002, 277:34017-34023.
159. Wilson P.D., Hovater J.S., Casey C.C., et al. ATP release mechanisms in primary cultures of epithelia derived from the cysts of polycystic kidneys. J Am Soc Nephrol 1999, 10:218-229.
160. Wilson P.D. Polycystic kidney disease. N Engl J Med 2004, 350:151-164.
161. i in rabbit cortical collecting duct. Am J Physiol Renal Physiol 2002, 283:F437-F446.
162. 2+ signaling and renin secretion in rat juxtaglomerular cells. Circ Res 2003, 93:338-345.
163. Yoshioka K., Saitoh O., Nakata H. Heteromeric association creates a P2Y-like adenosine receptor. Proc Natl Acad Sci U S A 2001, 98:7617-7622.
164. 1 receptors in living cells. FEBS Lett 2002, 523:147-151.
165. 1 receptors in rat brains. FEBS Lett 2002, 531:299-303.
166. Zhao H., Wiederkehr M.R., Fan L., et al. Acute inhibition of Na/H exchanger NHE-3 by cAMP. Role of protein kinase A and NHE-3 phosphoserines 552 and 605. J Biol Chem 1999, 274:3978-3987.
167. Zimmermann H. Extracellular metabolism of ATP and other nucleotides. Naunyn Schmiedebergs Arch Pharmacol 2000, 362:299-309.