Extracellular nucleotides regulate cellular functions of podocytes in culture

American Journal of Physiology - Renal Physiology

Volumn 281, Issue 6 50-6, 2001, Pages

  Fischer, Karl Georg ^a   Saueressig, Ulrich ^a   Jacobshagen, Claudius ^a   Wichelmann, Arndt ^a   Pavenstädt, Hermann ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Adenosine 5 triphosphate; Intracellular calcium concentration; Ion currents; Nucleotides; P2X7 receptor; Purinoceptor

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; ADENOSINE 5' O (3 THIOTRIPHOSPHATE); ADENOSINE TRIPHOSPHATE; NUCLEOTIDE; PURINE P2Y RECEPTOR; PURINE RECEPTOR; PURINERGIC RECEPTOR AFFECTING AGENT; PURINERGIC RECEPTOR BLOCKING AGENT; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SURAMIN; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; DEPOLARIZATION; ELECTROPHYSIOLOGY; GLOMERULUS; KIDNEY FUNCTION; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PATCH CLAMP; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0035665646     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2001.281.6.f1075     Document Type: Article

References (30)

1. 2+ mobilization by a nucleotide receptor in glomerular endothelial cells
2. Potential functional roles of extracellular ATP in kidney and urinary tract
3. Cloning, functional expression and tissue distribution of the human P2Y6 receptor
4. Ultrastructural organization of contractile and cytoskeletal proteins in glomerular podocytes of chicken, rat, and man
5. Hydrogen peroxide activates ion currents in rat mesangial cells
6. Simultaneous recording of the cell membrane potential and properties of the cell attached membrane of HT29 colon carcinoma and CF-PAC cells
7. NAD(P)H oxidase activity in cultured human podocytes: Effects of adenosine triphosphate
8. 2+ indicators with greatly improved fluorescence properties
9. Induction of proliferation and apoptotic cell death via P2Y and P2X receptors, respectively, in rat glomerular mesangial cells
10. Identification of P2X7 (P2Z) receptor in N18TG-2 cells and NG108-15 cells
11. Dysfunction of cell biological mechanisms of visceral epithelial cells (podocytes) in glomerular diseases
12. Adenosine and ATP: Progress in their receptors' structures and functions
13. A role for podocytes to counteract capillary wall distension
14. Synaptopodin: An actin-associated protein in telencephalic dendrites and renal podocytes
15. Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines
16. Nuclear localization of the protein encoded by the Wilm's tumor gene WT1 in embryonic and adult tissues
17. Cell cycle regulation and differentiation in the human podocyte lineage
18. Roles of the podocyte in glomerular function
19. Effect of extracellular ATP on contraction, cytosolic calcium activity, membrane voltage and ion currents of rat mesangial cells in primary culture
20. Agonist-induced activation of a non-selective ion current in glomerular endothelial cells
21. Effect of nucleotides on the cytosolic calcium activity and inositol phosphate formation in human glomerular epithelial cells
22. Extracellular ATP stimulates polyphosphoinositide hydrolysis and prostaglandin synthesis in rat renal mesangial cells. Involvement of a pertussis toxin-sensitive guanine nucleotide binding protein and feedback inhibition by protein kinase C
23. Modulation of anti-Thy1 nephritis in the rat by adenine nucleotides. Evidence for an anti-inflammatory role for nucleotidases
24. Receptors for purines and pyrimidines
25. Polycations induce calcium signaling in glomerular podocytes
26. Extracellular ATP causes apoptosis and necrosis of cultured mesangial cells via P2z/P2x7 receptors
27. Extracellular ATP stimulates proliferation of cultured mesangial cells via P2 purinergic receptors
28. Congenital nephrotic syndrome in mice lacking CD2-associated protein
29. Unraveling the mechanisms of glomerular ultrafiltration: Nephrin, a key component of the slit diaphragm
30. Molecular biology of P2Y purinoceptors: Expression in rat heart