P2 receptors in regulation of renal microvascular function

American Journal of Physiology - Renal Physiology

Volumn 280, Issue 6 49-6, 2001, Pages

  Inscho, Edward W ^a,b  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Afferent arteriole; Calcium signaling; Diadenosine polyphosphates; Extracellular nucleotides; Kidney; Mesangial cells; Microcirculation; Purinoceptors

Indexed keywords

PURINE P2 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; RECEPTOR SUBTYPE; VASOCONSTRICTOR AGENT;

ANIMAL CELL; ANIMAL TISSUE; BLOOD VESSEL TONE; CONTROLLED STUDY; GLOMERULUS CAPILLARY; HUMAN; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY VASCULAR RESISTANCE; MESANGIUM CELL; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

EID: 0034992502     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2001.280.6.f927     Document Type: Review

References (176)

1. Purinoceptors: Are there families of P2X and P2Y purinoceptors?
2. 1 receptor antagonist, on renal hemodynamics and urine formation in anesthetized dogs
3. P2 receptors in the kidney
4. Nucleotide receptors in the nervous system - An abundant component using diverse transduction mechanisms
5. 1 receptor-mediated renal vasoconstriction with endogenous nitric oxide and ANG II
6. Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase
7. Maxi-chloride channel in macula densa cells: Possible pathway for ATP release
8. Extracellular nucleotide receptor inhibits AVP-stimulated water permeability in inner medullary collecting duct
9. i in distal tubule cells. I. Evidence for a P2Y2 purinoceptor
10. 3H] α,β-methylene ATP binding sites in blood vessels
11. Molecular cloning and characterization of a novel ATP P2X receptor subtype from embryonic chick skeletal muscle
12. Increased flow-induced ATP release from isolated vascular endothelial cells but not smooth muscle cells
13. Increased release of ATP from endothelial cells during acute inflammation
14. α-adrenoceptor modulation of norepinephrine and ATP release in isolated kidneys of spontaneously hypertensive rats
15. 2-receptor modulation of noradrenergic neurotransmission in rat kidney
16. 2 receptor controlled by alternative splicing
17. 2+ mobilization by a nucleotide receptor in glomerular endothelial cells
18. Purinergic nerves
19. A basis for distinguishing two types of purinergic receptor
20. Purinoceptors: Ontogeny and phylogeny
21. Purinergic signalling: Therapeutic potential
22. Renal arteriolar angiotensin responses during varied adenosine receptor activation
23. Nucleotides mobilize intracellular calcium stores of renal proximal cells in primary culture: Existence of a suramin-sensitive mechanism
24. 2
25. 1 purinoceptors by autoradiography and immunohistochemistry in the rat kidney
26. Potential functional roles of extracellular ATP in kidney and urinary tract
27. Renal effects of selective adenosine receptor agonists in anesthetized rats
28. 2 purinergic receptors
29. 2Y receptors stimulate renin secretion by rat renal cortical slices
30. Receptors responsive to extracellular pyrimidine nucleotides
31. Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase
32. Advances in signalling by extracellular nucleotides: The role and transduction mechanisms of P2Y receptors
33. 2+-mobilizing receptors for ATP and UTP
34. - transport
35. Red blood cell regulation of microvascular tone through adenosine triphosphate
36. Interaction between adenosine and angiotensin II in renal microcirculation
37. Adenosine: An emerging role in the control of renal medullary oxygenation
38. Effects of adenosine on intrarenal oxygenation
39. 2-purinergic receptors for extracellular ATP and other nucleotides
40. Electrochemical and electrophysiological characterization of neurotransmitter release from sympathetic nerves supplying rat mesenteric arteries
41. Diadenosine polyphosphate-stimulated gluconeogenesis in isolated rat proximal tubules
42. Extracellular ATP and cell signalling
43. The erythrocyte as a regulator of vascular tone
44. 2 purinoceptors in the rat isolated perfused kidney
45. Extracellular ATP: A growth factor for vascular smooth muscle cells
46. Tyrphostin inhibition of ATP-stimulated DNA synthesis, cell proliferation and Fos-protein expression in vascular smooth muscle cells
47. Mitogenic effects of ATP on vascular smooth muscle cells vs. other growth factors and sympathetic cotransmitters
48. P2X receptors: Cloned and expressed
49. 2-purinoceptor activation in spontaneously hypertensive rats
50. 2-purinergic receptors in human breast tumor cells: Coupling of intracellular calcium signaling to anion secretion
51. Abundant amounts of diadenosine 5′,5‴-P1,P4-tetraphosphate are present and releasable, but metabolically inactive, in human platelets
52. The effects of diadenosine polyphosphates on the cardiovascular system
53. An estimate of ATP release into the venous effluent from exercising human forearm muscle
54. Identification of ATP in human plasma and the concentration in the venous effluent of forearm muscles before, during and after sustained contractions
55. Nomenclature and classification of purinoceptors
56. Towards a revised nomenclature for P1 and P2 receptors
57. Adenosine (P1) receptor signalling
58. In vivo effects of diadenosine polyphosphates on rat renal microcirculation
59. Influence of cell culture conditions and passage number on the response of membrane voltage to ATP and angiotensin II in rat mesangial cells
60. CFTR-independent ATP release from epithelial cells triggered by mechanical stimuli
61. Calcium response to adenosine and ATP in rabbit afferent arterioles
62. 2+ response of rat mesangial cells to ATP analogues
63. Induction of proliferation and apoptotic cell death via P2Y and P2X receptors, respectively, in rat glomerular mesangial cells
64. 2-purinergic receptors: Subtype-associated signaling responses and structure
65. 4 nucleotide receptors are involved in the regulation of rat aortic smooth muscle cells by UTP and ATP
66. The macula densa: Recent developments
67. 2A adenosine receptor mediated potassium channel activation in rat epididymal smooth muscle
68. - channels
69. Effects of diadenosine polyphosphates on renal function and blood pressure in anesthetized Wistar rats
70. 2 receptor (-/-) mice
71. UTP and ATP induce different membrane voltage responses in rat mesangial cells
72. Feedback regulation of extracellular ATP-stimulated phosphoinositide hydrolysis by protein kinase C-α in bovine glomerular endothelial cells
73. Stimulation by extracellular ATP and UTP of the mitogen-activated protein kinase cascade and proliferation of rat renal mesangial cells
74. Stimulation by extracellular ATP and UTP of the stress-activated protein kinase cascade in rat renal mesangial cells
75. Extracellular nucleotides activate the p38-stress-activated protein kinase cascade in glomerular mesangial cells
76. Purinoceptor-mediated regulation of the renal microvasculature
77. Extracellular ATP increases cytosolic calcium in cultured renal arterial smooth muscle cells
78. 2 purinergic stimulation
79. Effect of calcium channel blockade on UTP-mediated afferent arteriolar vasoconstriction
80. Direct assessment of renal microvascular responses to P2-purinoceptor agonists
81. 2-purinoceptor activation
82. Purinoceptor-mediated calcium signaling in preglomerular smooth muscle cells
83. Extracellular ATP in the regulation of renal microvascular function
84. Calcium activation mechanisms in the renal microvascular response to extracellular ATP
85. Effects of ATP on pre- and postglomerular juxtamedullary microvasculature
86. 2+ signaling in preglomerular smooth muscle cells
87. 2u receptors
88. 3 receptors: Novel ligands and paradoxical effects
89. 3 adenosine receptors: Protective vs. damaging effects identified using novel agonists and antagonists
90. 2+ is not required
91. The selective response to adenosine of renal microvessels from hamster explants
92. 2X purinoceptors be classified pharmacologically?
93. Effects of diadenosine polyphosphates on systemic and regional hemodynamics in anesthetized rats
94. Metabotropic receptors for ATP and UTP: Exploring the correspondence between native and recombinant nucleotide receptors
95. 2 purinoceptor in rat renal inner medulla and lung
96. Effects of diadenosine polyphosphates, ATP and angiotensin II on membrane voltage and membrane conductances of rat mesangial cells
97. 2 receptor subtypes in the cardiovascular system
98. 2 receptor
99. 2 receptor
100. The presence of diadenosine 5′,5‴ P1,P3-triphosphate (Ap3A) in human platelets
101. P2 purinoceptor saturation by adenosine triphosphate impairs renal autoregulation in dogs
102. Suppression of blood flow autoregulation plateau during nitric oxide blockade in canine kidney
103. 2u partially mediates ATP-induced cell progression of aortic smooth muscle cells
104. Adenosine-induced renal vasoconstriction in man
105. Adenosine and angiotensin system interact in the regulation of renal microcirculation in humans
106. Modulation of tubuloglomerular feedback responsiveness by extracellular ATP
107. Renal adenosine As receptors in the rat: Assessment of functional role
108. 1 receptors
109. Effects of adenosine receptor agonists in the isolated, perfused rat kidney
110. Concentration dependency of the renal vascular and renin secretory responses to adenosine receptor agonists
111. Paracrine regulation of the renal microcirculation
112. Cloning and characterization of the murine P2XM receptor gene
113. Stimulation of prostaglandin biosynthesis by adenine nucleotides
114. Relation between renal interstitial ATP concentrations and autoregulation-mediated changes in renal vascular resistance
115. Renal interstitial concentration of adenosine during endotoxin shock
116. Pharmacology of cloned P2X receptors
117. Adenine dinucleotides: A novel class of signalling molecules
118. Adenosine receptors in the cardiovascular system
119. Cardiovascular purinoceptors
120. 2A receptors
121. Adenosine mediates tubuloglomerular feedback response: An element of metabolic control of kidney function
122. Renal action of adenosine: Effect on renin secretion in the rat
123. Extracellular ATP and UTP trigger calcium entry in mouse cortical thick ascending limbs
124. Effect of extracellular ATP on contraction, cytosolic calcium activity, membrane voltage, and ion currents of rat mesangial cells in primary culture
125. Extracellular ATP regulates glomerular endothelial cell function
126. Effect of nucleotides on the cytosolic free calcium activity and inositol phosphates in human glomerular epithelial cells
127. Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides
128. Comparison of extracellular ATP and UTP signalling in rat renal mesangial cells
129. Extracellular ATP stimulates polyphosphoinositide hydrolysis and prostaglandin synthesis in rat renal mesangial cells
130. Proliferative mechanisms in kidney cells
131. Extracellular ATP and UTP activation of phospholipase D is mediated by protein kinase C-ε in rat renal mesangial cells
132. Increased sensitivity of the renal vasculature to adenosine in streptozotocininduced diabetes mellitus rats
133. 2A adenosine receptor-mediated dilation of the pressurized renal arcuate artery
134. P2 receptors in the central and peripheral nervous systems modulating sympathetic vasomotor tone
135. Receptors for purines and pyrimidines
136. - conductance
137. Extracellular ATP in the human kidney: Mode of release and vascular effects
138. Purinoceptors mediate renal vasodilation by nitric oxide dependent and independent mechanisms
139. 2+ activity and contraction of rat mesangial cells
140. + exchange by diadenosine polyphosphates, angiotensin II and vasopressin in rat cortical collecting duct
141. Diadenosine phosphates and the physiological control of blood pressure
142. Vascular actions of diadenosine phosphates
143. Juxtaglomerular cell complex in the regulation of renal salt excretion
144. Natriuretic peptides and diadenosine polyphosphates modulate pH regulation of rat mesangial cells
145. P2U-purinergic receptor activation mediates inhibition of cAMP accumulation in cultured renal mesangial cells
146. 7 receptors
147. Extracellular nucleotides as signalling molecules for renal mesangial cells
148. 2-purinergic receptors
149. Renal periarterial nerve stimulation-induced vasoconstriction at low frequencies is primarily due to release of a purinergic transmitter in the rat
150. Extracellular nucleotide signaling along the renal epithelium
151. 2 receptor
152. Sodium intake markedly alters renal interstitial fluid adenosine
153. Effects of adenosine on renin release from isolated rat glomeruli and kidney slices
154. Nuclear and cytosolic calcium signaling induced by extracellular ATP in rat kidney inner medullary collecting duct cells
155. ATP-induced calcium mobilization in glomerular mesangial cells is mediated by P2u purinoceptor
156. 2 purinoceptors
157. ATP release caused by bradykinin, substance P and histamine from intact and cultured smooth muscles of guinea-pig vas deferens
158. ATP in in vitro perfused hydronephrotic rat kidney
159. Bioluminescence detection of ATP release mechanisms in epithelia
160. Diadenosine polyphosphates induce transplasma membrane calcium influx in cultured glomerular mesangial cells
161. Diadenosine polyphosphates' action on calcium and vessel contraction
162. Adenosine formed by 5′-nucleotidase mediates tubuloglomerular feedback
163. 2x receptor for extracellular ATP
164. 6A in the isolated perfused rat kidney
165. Mediation of the vasoactive properties of diadenosine tetraphosphate via various purinoceptors
166. Differential effects of diadenosine phosphates on purinoceptors in the rat isolated perfused kidney
167. Renal vascular reactivity to ATP in ageing rats
168. Renal vascular reactivity to ATP in hyper- and hypothyroid rats
169. 2x-purinoceptor agonist β,γ-methylene-L-ATP in human cutaneous and renal blood vessels
170. Extracellular ATP and ADP stimulate proliferation of porcine aortic smooth muscle cells
171. Vasomotor effects of purinergic agonists in isolated rabbit afferent arterioles
172. Synergistic effects of angiotensin and adenosine in the renal microvasculature
173. Calcium signaling pathways utilized by P2X receptors in preglomerular MVSMC
174. Selectivity of diadenosine polyphosphates for rat P2X receptor subunits
175. The action of angiotensin II on the intracellular sodium content of suspensions of rat proximal tubules
176. i increase by extracellular ATP in isolated rabbit renal proximal tubules