Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors

Biochemical Pharmacology

Volumn 67, Issue 9, 2004, Pages 1763-1770

  Mamedova, Liaman K ^a   Joshi, Bhalchandra V ^a   Gao, Zhan Guo ^a   Von Kügelgen, Ivar ^b   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

2 chloro N6 methyl (N) methanocarba 2 deoxyadenosine 3 ,5 bisphosphate; 4,4 diisothiocyanatostilbene 2, 2 disulfonic acid disodium salt; Chinese hamster ovary; CHO; DIDS; MRS2279; PIA

Indexed keywords

1,4 DIPHENYLTHIOUREIDOBUTANE; ADENOSINE TRIPHOSPHATE; BIBENZYL; BITOSCANATE; MRS 2567; MRS 2575; MRS 2578; NUCLEOTIDE; PHOSPHOLIPASE C; RECEPTOR PROTEIN; RECEPTOR SUBTYPE; THIOCYANATE; THIOCYANIC ACID DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

APOPTOSIS; ARTICLE; CELL PROTECTION; DRUG INHIBITION; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BLOCKING;

ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; HUMANS; INOSITOL PHOSPHATES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PURINERGIC P2; THIOCYANATES; TUMOR CELLS, CULTURED;

EID: 1842634568     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.01.011     Document Type: Article

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