Genetic basis of inherited macular dystrophies and implications for stem cell therapy

Stem Cells

Volumn 27, Issue 11, 2009, Pages 2833-2845

  Mellough, Carla B ^a   Steel, David H W ^b   Lako, Majlinda ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b SUNDERLAND EYE INFIRMARY   (United Kingdom)

Author keywords

Cell therapy; Embryonic stem cells; Gene therapy; Hereditary disease; Induced pluripotency; Macular degeneration; Retinal photoreceptors; Stem cells

Indexed keywords

AMYLOID BETA PROTEIN; ANTIOXIDANT; FIBULIN; GENE THERAPY AGENT; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; NEUROPROTECTIVE AGENT; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR SOX2;

ALZHEIMER DISEASE; AUTOSOMAL DOMINANT DISORDER; AUTOSOMAL DOMINANT INHERITANCE; AUTOSOMAL RECESSIVE INHERITANCE; CHINESE; COLOR BLINDNESS; DIABETIC RETINOPATHY; DRUG MEGADOSE; EPIDEMIOLOGICAL DATA; EXPERIMENTAL MODEL; EXPERIMENTAL MOUSE; GENE LOCUS; GENE MUTATION; GENE THERAPY; GENETIC SCREENING; HUMAN; LATE ONSET RETINAL DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PHOTORECEPTOR; PLURIPOTENT STEM CELL; RETINA DEGENERATION; RETINA DISEASE; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA DEGENERATION; REVIEW; SIGNAL TRANSDUCTION; STARGARDT DISEASE; STEM CELL TRANSPLANTATION; SUBRETINAL NEOVASCULARIZATION; TECHNOLOGY; VISION; VISUAL ACUITY;

ANIMALS; GENE THERAPY; HUMANS; MACULAR DEGENERATION; MODELS, BIOLOGICAL; STEM CELL TRANSPLANTATION; TISSUE THERAPY;

EID: 72849127793     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.159     Document Type: Review

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