Human photoreceptor transplantation in retinitis pigmentosa: A safety study

Archives of Ophthalmology

Volumn 115, Issue 9, 1997, Pages 1168-1172

  Kaplan, Henry J ^a   Tezel, Tongalp H ^a   Berger, Adam S ^a   Wolf, Mitchel L ^a   Del Priore, Lucian V ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CASE REPORT; CELL TRANSPLANTATION; ELECTRORETINOGRAPHY; FEMALE; FLUORESCENCE ANGIOGRAPHY; HUMAN; MALE; NERVE CELL NETWORK; OPHTHALMOSCOPY; PHOTORECEPTOR CELL; PRIORITY JOURNAL; RETINA CONE; RETINA MACULA LUTEA; RETINITIS PIGMENTOSA; SAFETY; SCANNING LASER OPHTHALMOSCOPY; SURGICAL TECHNIQUE; VISUAL ACUITY;

EID: 0030924162     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.1997.01100160338012     Document Type: Article

References (24)

1. Berson EL. Retinitis pigmentosa: unfolding its mystery. Proc Natl Acad Sci U S A. 1996;93:4526-4528.
2. Kajiwara K, Berson EL, Dryja TP. Digenic retinitis pigmentosa due to mutations at the unlinked peripherin/RDS and ROM1 loci. Science. 1994;264:1604-1608.
3. Dryja TP, McGee TL, Reichel E, et al. A point mutation of the rhodopsin gene in one form of retinitis pigmentosa. Nature. 1990;343:364-366.
4. Farrar GJ, Kenna P, Jordan SA, et al. A three-base-pair deletion in the peripherinRDS gene in one form of retinitis pigmentosa. Nature. 1991;354:478-480.
5. Kajiwara K, Hahn LB, Mukai S, Travis GH, Berson EL, Dryja TP. Mutations in the human retinal degeneration slow gene in autosomal dominant retinitis pigmentosa. Nature. 1991;354:480-483.
6. McLaughlin ME, Sandberg MA, Berson EL, Dryja TP. Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa. Nat Genet. 1993;4:130-134.
7. Dryja TP, Finn JT, Peng YW, McGee TL, Berson EL, Yau KW. Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa. Proc Natl Acad Sci U S A. 1995;92:10177-10181.
8. Huang SH, Pittler SJ, Huang X, Oliveira L, Berson EL, Dryja TP. Autosomal recessive retinitis pigmentosa caused by mutations in the alpha subunit of rod cGMP phosphodiesterase. Nat Genet. 1995;11:468-471.
9. Bascom RA, Liu L, Heckenlively JR, Stone EM, Mclnnes RR. Mutation analysis of the ROM1 gene in retinitis pigmentosa. Hum Mol Genet. 1995;4:1895-1902.
10. Weil D, Blanchard S, Kaplan J, et al. Defective myosin VIIA gene responsible for Usher syndrome type 1B. Nature. 1995;374:60-61.
11. Bennett J, Tanabe T, Sun D, et al. Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy. Nat Med. 1996;2:649-654.
12. Silverman MS, Hughes SE, Valentino TL, Liu Y. Photoreceptor transplantation: anatomic, electrophysiologic, and behavioral evidence for the functional reconstruction of retinas lacking photoreceptors. Exp Neurol. 1992;115:87-94.
13. Silverman MS, Hughes SE. Transplantation of photoreceptors to light-damaged retina. Invest Ophthalmol Vis Sci. 1989;30:1684-1690.
14. Haugland RP, Larison KD. Ruorescent dyes for assessing vital cell functions. In: Handbook of Fluorescent Probes and Research Chemicals. 5th ed. Eugene, Ore: Molecular Probes; 1994:172-180.
15. Poole CA, Brookes NH, Clover GM. Keratocyte networks visualized in the living cornea using vital dyes. J Cell Sci. 1993;106:685-692.
16. Means TL, Geroski DH, Hadley A, Lynn MJ, Edethauser HF. Viability of human comeal endothelium following optisol-GS storage. Arch Ophthalmol. 1995;113:806-809.
17. Stone JL, Barlow WE, Humayun MS, de Juan E Jr, Milam AH. Morphometric analysis of macular photoreceptors and ganglion cells in retinas with retinitis pigmentosa. Arch Ophthalmol. 1992;110:1634-1639.
18. Humayun MS, de Juan E Jr, Dagnelie G, Greenberg RJ, Propst RH, Phillips DH. Visual perception elicited by electrical stimulation of retina in blind humans. Arch Ophthalmol. 1996;114:40-46.
19. Gouras P, Du J, Gelanze M, et al. Survival and synapse formation of transplanted rat rods. J Neurol Transplant Plast. 1991;2:91-100.
20. Del Cerro M, Ison JR, Bowen GP, Lazar E, del Cerro C. Intraretinal grafting restores visual function in light-blinded rats. Neuroreport. 1991;2:529-532.
21. Adolph AR, Zucker CL, Ehinger B, Bergström A. Function and structure in retinal transplants. J Neurol Transplant Plast. 1994;5:147-161.
22. Silverman MS, Lett J, Valentine TL, Landgraf M, Wang X. Rescue of host cones by transplanted donor photoreceptors in the rd mouse. Invest Ophthalmol Vis Sci. 1993;34:1096. Abstract.
23. Silbert JE, Gao E-K, Yu X-H, Kaplan HJ. Adult murine retinal pigment epithelium Is immunogenic. Invest Ophthalmol Vis Sci. 1994;35:1525. Abstract.
24. Jiang LQ, Jorquera M, Streilein JW. Immunologic consequences of intraocular implantation of retinal pigment epithelial allografts. Exp Eye Res. 1994;58:719-728.