-
1
-
-
0022540321
-
Cpg-rich islands and the function of dna methylation
-
Bird AP. CpG-rich islands and the function of DNA methylation. Nature 1986; 321: 209-213.
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
3
-
-
0030846212
-
Alterations in dna methylation: A fundamental aspect of neoplasia
-
Baylin SB, Herman JG, Graff JR, Vertino PM, Issa JP. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv. Cancer Res. 1998; 72: 141-196.
-
(1998)
Adv. Cancer Res
, vol.72
, pp. 141-196
-
-
Baylin, S.B.1
Herman, J.G.2
Graff, J.R.3
Vertino, P.M.4
Issa, J.P.5
-
4
-
-
0035228079
-
X-chromosome inactivation: Counting, choice and initiation
-
Avner P, Heard E. X-chromosome inactivation: counting, choice and initiation. Nat. Rev. Genet. 2001; 2 (1): 59-67.
-
(2001)
Nat. Rev. Genet
, vol.2
, Issue.1
, pp. 59-67
-
-
Avner, P.1
Heard, E.2
-
5
-
-
0032694084
-
Dna methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a cpg-rich promoter
-
De Smet C, Lurquin C, Lethe B, Martelange V, Boon T. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. Mol. Cell. Biol. 1999; 19: 7327-7335.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 7327-7335
-
-
De Smet, C.1
Lurquin, C.2
Lethe, B.3
Martelange, V.4
Boon, T.5
-
6
-
-
0034174495
-
Dna methylation and histone acetylation of rat methionine adenosyltransferase 1a and 2a genes is tissue-specific
-
Torre L, Lopez-Rodas G, Latasa MU, Carretero MV, Boukaba A, Rodriguez JL. DNA methylation and histone acetylation of rat methionine adenosyltransferase 1A and 2A genes is tissue-specific. Int. J. Biochem. Cell. Biol. 2000; 32: 397-404.
-
(2000)
Int. J. Biochem. Cell. Biol
, vol.32
, pp. 397-404
-
-
Torre, L.1
Lopez-Rodas, G.2
Latasa, M.U.3
Carretero, M.V.4
Boukaba, A.5
Rodriguez, J.L.6
-
7
-
-
33947315736
-
Cancer epigenomics: Dna methylomes and histone-modification maps
-
Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat. Rev. Genet. 2007; 8(4): 286-298.
-
(2007)
Nat. Rev. Genet
, vol.8
, Issue.4
, pp. 286-298
-
-
Esteller, M.1
-
8
-
-
0018776724
-
Becker ff. 5-methylcytosine content of nuclear dna during chemical hepatocarcinogenesis and in carcinomas which result
-
Lapeyre JN, Becker FF. 5-methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result. Biochem. Biophys. Res. Comm. 1979; 87: 698-705.
-
(1979)
Biochem. Biophys. Res. Comm
, vol.87
, pp. 698-705
-
-
Lapeyre, J.N.1
-
10
-
-
4143140030
-
A mouse skin multistage carcinogenesis model reflects the aberrant dna methylation patterns of human tumors
-
Fraga MF, Herranz M, Espada J, Ballestar E, Paz MF, Ropero S et al. A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors. Cancer Res. 2004; 64: 5527-5534.
-
(2004)
Cancer Res
, vol.64
, pp. 5527-5534
-
-
Fraga, M.F.1
Herranz, M.2
Espada, J.3
Ballestar, E.4
Paz, M.F.5
Ropero, S.6
-
11
-
-
0035065510
-
Retrotransposons as epigenetic mediators of phenotypic variation in mammals
-
Whitelaw E, Martin DI. Retrotransposons as epigenetic mediators of phenotypic variation in mammals. Nat. Genet. 2001; 27: 361-365.
-
(2001)
Nat. Genet
, vol.27
, pp. 361-365
-
-
Whitelaw, E.1
Martin, D.I.2
-
12
-
-
0033547330
-
Chromosome instability and immunodeficiency syndrome caused by mutations in a dna methyltransferase gene
-
Xu GL, Bestor TH, Bourc'his D, Hsieh CL, Tommerup N, Bugge M, Hulten M, Qu X, Russo JJ, Viegas-Péquignot E. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 1999; 402(6758): 187-191.
-
(1999)
Nature
, vol.402
, Issue.6758
, pp. 187-191
-
-
Xu, G.L.1
Bestor, T.H.2
Bourc'his, D.3
Hsieh, C.L.4
Tommerup, N.5
Bugge, M.6
Hulten, M.7
Qu, X.8
Russo, J.J.9
Viegas-Péquignot, E.10
-
13
-
-
0020699979
-
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
-
Feinberg AP, Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1999; 301: 89-92.
-
(1999)
Nature
, vol.301
, pp. 89-92
-
-
Feinberg, A.P.1
Vogelstein, B.2
-
14
-
-
9444266573
-
Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (Ext1) disrupts heparan sulfate synthesis in cancer cells
-
Ropero S, Setien F, Espada J, Fraga MF, Herranz M, Asp J et al. Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells. Hum. Mol. Genet. 2004; 13: 2753-2765.
-
(2004)
Hum. Mol. Genet
, vol.13
, pp. 2753-2765
-
-
Ropero, S.1
Setien, F.2
Espada, J.3
Fraga, M.F.4
Herranz, M.5
Asp, J.6
-
15
-
-
33745056414
-
Epigenetic inac-tivation of the premature aging werner syndrome gene in human cancer
-
Agrelo R, Cheng WH, Setien F, Ropero S, Espada J, Fraga MF et al. Epigenetic inac-tivation of the premature aging Werner syndrome gene in human cancer. Proc. Natl. Acad. Sci. USA 2006; 103: 8822-8827.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8822-8827
-
-
Agrelo, R.1
Cheng, W.H.2
Setien, F.3
Ropero, S.4
Espada, J.5
Fraga, M.F.6
-
16
-
-
0942279488
-
Generating mutations but providing chemosensitivity: The role of o6-methylguanine dna methyltransferase in human cancer
-
Esteller M, Herman JG. Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer. Oncogene 2004; 23: 1-8.
-
(2004)
Oncogene
, vol.23
, pp. 1-8
-
-
Esteller, M.1
Herman, J.G.2
-
18
-
-
0343621494
-
Aberrant cpg-island methylation has non-random and tumour-type-specific patterns
-
Costello JF, Fruhwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X et al. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat. Genet. 2000; 24: 132-138.
-
(2000)
Nat. Genet
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
-
19
-
-
18244388241
-
Dna methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
-
Esteller M, Fraga MF, Guo M, Garcia-Foncillas J, Hedelfank I, Godwin AK et al. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum. Mol. Genet. 2001; 10: 3001-3007.
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 3001-3007
-
-
Esteller, M.1
Fraga, M.F.2
Guo, M.3
Garcia-Foncillas, J.4
Hedelfank, I.5
Godwin, A.K.6
-
20
-
-
18244388241
-
-
Esteller M, Fraga MF, Guo M, Garcia-Foncillas J, Hedelfank I, Godwin AK et al. Hum. Mol. Genet. 2001b; 10: 3001-3007.
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 3001-3007
-
-
Esteller, M.1
Fraga, M.F.2
Guo, M.3
Garcia-Foncillas, J.4
Hedelfank, I.5
Godwin, A.K.6
-
21
-
-
34547792388
-
Epigenetic gene silencing in cancer: The dna hypermethylome
-
Esteller M. Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum. Mol. Genet. 2007; 16 (1): R50-R59.
-
(2007)
Hum. Mol. Genet
, vol.16
, Issue.1
, pp. R50-R59
-
-
Esteller, M.1
-
22
-
-
0038527642
-
Methyltransferase recruitment and dna hypermethylation of target promoters by an oncogenic transcription factor
-
Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M et al. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 2002; 295:1079-1082.
-
(2002)
Science
, vol.295
, pp. 1079-1082
-
-
Di Croce, L.1
Raker, V.A.2
Corsaro, M.3
Fazi, F.4
Fanelli, M.5
-
23
-
-
18544364773
-
Cancer epigenetics and methylation
-
Esteller M, Fraga MF, Paz MF, Campo E, Colomer D, et al. Cancer epigenetics and methylation. Science 2002; 297: 1807-1808.
-
(2002)
Science
, vol.297
, pp. 1807-1808
-
-
Esteller, M.1
Fraga, M.F.2
Paz, M.F.3
Campo, E.4
Colomer, D.5
-
24
-
-
32844459336
-
The polycomb group protein ezh2 directly controls dna methylation
-
Vire E, Brenner C, Deplus R, Blanchon L, Fraga M, Didelot C et al. The Polycomb group protein EZH2 directly controls DNA methylation. Nature 2006; 439: 871-874.
-
(2006)
Nature
, vol.439
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
Blanchon, L.4
Fraga, M.5
Didelot, C.6
-
25
-
-
33846649587
-
Poly-comb-mediated methylation on lys27 of histone h3 pre-marks genes for de novo methylation in cancer
-
Schlesinger Y, Straussman R, Keshet I, Farkash S, Hecht M, Zimmerman J et al. Poly-comb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat. Genet. 2006; 39: 232-236.
-
(2006)
Nat. Genet
, vol.39
, pp. 232-236
-
-
Schlesinger, Y.1
Straussman, R.2
Keshet, I.3
Farkash, S.4
Hecht, M.5
Zimmerman, J.6
-
26
-
-
3042767202
-
Micrornas: Small rnas with a big role in gene regulation
-
He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 2004; 5: 522-531.
-
(2004)
Nat. Rev. Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
27
-
-
24344494340
-
How micrornas control cell division, differentiation and death
-
Miska EA. How microRNAs control cell division, differentiation and death. Curr. Opin. Genet. 2005; 5: 563-568.
-
(2005)
Curr. Opin. Genet
, vol.5
, pp. 563-568
-
-
Miska, E.A.1
-
28
-
-
20444460289
-
Microrna expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D et al. MicroRNA expression profiles classify human cancers. Nature 2005; 435: 834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
-
29
-
-
33750370444
-
Croce cm. Microrna signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat. Rev. Cancer 2006; 6: 857-866.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
-
30
-
-
33744805399
-
Specific activation of microrna-127 with downregulation of the proto-oncogene bcl6 by chromatin-modifying drugs in human cancer cells
-
Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA, Jones PA. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006; 9: 435-443.
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
Friedman, J.M.4
Chuang, J.C.5
Coetzee, G.A.6
Jones, P.A.7
-
31
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microrna in human cancer cells
-
Lujambio A, Ropero S, Ballestar E, Fraga MF, Cerrato C, Setien F et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res. 2007; 67: 1424-1429.
-
(2007)
Cancer Res
, vol.67
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
Fraga, M.F.4
Cerrato, C.5
Setien, F.6
-
32
-
-
0031415710
-
Oncogenic mechanism mediated by dna methylation
-
Laird PW. Oncogenic mechanism mediated by DNA methylation. Mol. Med. Today 1997; 3: 223-229.
-
(1997)
Mol. Med. Today
, vol.3
, pp. 223-229
-
-
Laird, P.W.1
-
33
-
-
0029843950
-
Methylation-specific pcr: A novel pcr assay for methylation status of cpg islands
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. USA 1996; 93: 9821-9826.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
34
-
-
0036753290
-
Dna methylation: A profile of methods and applications
-
Fraga MF, Esteller M. DNA methylation: a profile of methods and applications. Biotechniques 2002; 632: 636-649.
-
(2002)
Biotechniques
, vol.632
, pp. 636-649
-
-
Fraga, M.F.1
Esteller, M.2
-
35
-
-
0035930097
-
Quantitation of gstp1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma
-
Jerónimo C, Usadel H, Henrique R, Oliveira J, Lopes C, Nelson WG, Sidransky D. Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma. J. Nat. Cancer Inst. 2001; 93(22): 1747-1752.
-
(2001)
J. Nat. Cancer Inst
, vol.93
, Issue.22
, pp. 1747-1752
-
-
Jerónimo, C.1
Usadel, H.2
Henrique, R.3
Oliveira, J.4
Lopes, C.5
Nelson, W.G.6
Sidransky, D.7
-
36
-
-
34250802601
-
Gene methylation and early detection of genitourinary cancer
-
Cairns P. Gene methylation and early detection of genitourinary cancer. Nat. Rev. Cancer 2007; 7: 531-543.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 531-543
-
-
Cairns, P.1
-
37
-
-
0033577058
-
Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer
-
Ahrendt SA, Chow JT, Xu L, Yang SC, Eisenberger CF, Esteller M et al. Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer. J. Nat. Cancer Inst. 1999; 91: 332-339.
-
(1999)
J. Nat. Cancer Inst
, vol.91
, pp. 332-339
-
-
Ahrendt, S.A.1
Chow, J.T.2
Xu, L.3
Yang, S.C.4
Eisenberger, C.F.5
Esteller, M.6
-
38
-
-
0032862226
-
Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence
-
Sanchez-Cespedes M, Esteller M, Hibi K, Cope FO, Westra WH, Piantadosi S, et al. Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence. Clin. Cancer Res. 1999; 5: 2450-2454.
-
(1999)
Clin. Cancer Res
, vol.5
, pp. 2450-2454
-
-
Sanchez-Cespedes, M.1
Esteller, M.2
Hibi, K.3
Cope, F.O.4
Westra, W.H.5
Piantadosi, S.6
-
39
-
-
4544250024
-
Gene-promoter hypermethylation as a biomarker in lung cancer
-
Belinsky SA. Gene-promoter hypermethylation as a biomarker in lung cancer. Nat. Rev. Cancer 2004; 4 (9): 707-717.
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.9
, pp. 707-717
-
-
Belinsky, S.A.1
-
40
-
-
0034808413
-
Molecular detection of prostate cancer in urine by gstp1 hypermethylation
-
Cairns P, Esteller M, Herman JG, Schoenberg M, Jeronimo C, Sanchez-Cespedes M et al. Molecular detection of prostate cancer in urine by GSTP1 hypermethylation. Clin. Cancer Res. 2001; 7: 2727-2730.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 2727-2730
-
-
Cairns, P.1
Esteller, M.2
Herman, J.G.3
Schoenberg, M.4
Jeronimo, C.5
Sanchez-Cespedes, M.6
-
41
-
-
0034327356
-
Fluorescent methylation-specific polymerase chain reaction for dna-based detection of prostate cancer in bodily fluids
-
Goessl C, Krause H, Muller M, Heicappell R, Schrader M, Sachsinger J, Miller K. Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids. Cancer Res. 2000; 60: 5941-5945.
-
(2000)
Cancer Res
, vol.60
, pp. 5941-5945
-
-
Goessl, C.1
Krause, H.2
Muller, M.3
Heicappell, R.4
Schrader, M.5
Sachsinger, J.6
Miller, K.7
-
42
-
-
18844470774
-
Detection of breast cancer cells in ductal lavage fluid by methylation-specific pcr
-
Evron E, Dooley WC, Umbricht CB, Rosenthal D, Sacchi N, Gabrielson E et al. Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR. Lancet 2001; 357: 1335-1336.
-
(2001)
Lancet
, vol.357
, pp. 1335-1336
-
-
Evron, E.1
Dooley, W.C.2
Umbricht, C.B.3
Rosenthal, D.4
Sacchi, N.5
Gabrielson, E.6
-
43
-
-
0035116695
-
Promoter hypermethylation patterns of p16, o6-methylguanine-dna-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients
-
Rosas SL, Koch W, da Costa Carvalho MG, Wu L, Califano J, Westra W et al. Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients. Cancer Res. 2001; 61: 939-942.
-
(2001)
Cancer Res
, vol.61
, pp. 939-942
-
-
Rosas, S.L.1
Koch, W.2
Da Costa Carvalho, M.G.3
Wu, L.4
Califano, J.5
Westra, W.6
-
44
-
-
20444374483
-
Circulating tumour-derived dna and rna markers in blood: A tool for early detection, diagnostics, and follow-up
-
Bremnes RM, Sirera R, Camps C. Circulating tumour-derived DNA and RNA markers in blood: A tool for early detection, diagnostics, and follow-up? Lung Cancer 2005; 49 (1): 1-12.
-
(2005)
Lung Cancer
, vol.49
, Issue.1
, pp. 1-12
-
-
Bremnes, R.M.1
Sirera, R.2
Camps, C.3
-
45
-
-
11144356831
-
Methylation changes in faecal dna: A marker for colorectal cancer screening
-
Muller HM, Oberwalder M, Fiegl H, Morandell M, Goebel G, Zitt M. Methylation changes in faecal DNA: A marker for colorectal cancer screening? Lancet 2004; 363(9417): 1283-1285.
-
(2004)
Lancet
, vol.363
, Issue.9417
, pp. 1283-1285
-
-
Muller, H.M.1
Oberwalder, M.2
Fiegl, H.3
Morandell, M.4
Goebel, G.5
Zitt, M.6
-
46
-
-
0037354547
-
Dna methylation, a biomarker for colorectal cancer: Implications for screening and pathological utility
-
Jubb AM, Quirke P, Oates AJ. DNA methylation, a biomarker for colorectal cancer: Implications for screening and pathological utility. Ann. N.Y. Acad. Sci. 2003; 983: 251-267.
-
(2003)
Ann. N.Y. Acad. Sci
, vol.983
, pp. 251-267
-
-
Jubb, A.M.1
Quirke, P.2
Oates, A.J.3
-
47
-
-
0032894125
-
Detection of aberrant promoter methylation of tumor suppressor genes in serum dna from non-small cell lung cancer patients
-
Esteller M, Sanchez-Cespedes M, Rosell R, Sidransky D, Baylin SB, Herman JG. Detection of aberrant promoter methylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res. 1999; 59: 67-70.
-
(1999)
Cancer Res
, vol.59
, pp. 67-70
-
-
Esteller, M.1
Sanchez-Cespedes, M.2
Rosell, R.3
Sidransky, D.4
Baylin, S.B.5
Herman, J.G.6
-
48
-
-
33748516842
-
A real-time pcr test for septin 9 gene methylation identifies early stage colorectal cancer in plasma
-
Lofton-Day C, Model F, Tetzner R, DeVos T, Schuster M, Lesche R, Sledziewski A, Day RW. A real-time PCR test for septin 9 gene methylation identifies early stage colorectal cancer in plasma. Proc. Am. Assoc. Cancer Res. 2006; 47: LB-224.
-
(2006)
Proc. Am. Assoc. Cancer Res
, vol.47
, pp. LB-224
-
-
Lofton-Day, C.1
Model, F.2
Tetzner, R.3
DeVos, T.4
Schuster, M.5
Lesche, R.6
Sledziewski, A.7
Day, R.W.8
-
49
-
-
13844320649
-
Aberrant dna methylation as a cancer-inducing mechanism
-
Esteller M. Aberrant DNA methylation as a cancer-inducing mechanism. Annu. Rev. Pharmacol. Toxicol. 2005; 45: 629-656.
-
(2005)
Annu. Rev. Pharmacol. Toxicol
, vol.45
, pp. 629-656
-
-
Esteller, M.1
-
50
-
-
0034692447
-
Hypermethylation of the death-associated protein (Dap) kinase promoter and aggressiveness in stage i non-small-cell lung cancer
-
Tang X, Khuri FR, Lee JJ, Kemp BL, Liu D, Hong WK, Mao L. Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage I non-small-cell lung cancer. J. Nat. Cancer. Inst. 2000; 92: 1511-1516.
-
(2000)
J. Nat. Cancer. Inst
, vol.92
, pp. 1511-1516
-
-
Tang, X.1
Khuri, F.R.2
Lee, J.J.3
Kemp, B.L.4
Liu, D.5
Hong, W.K.6
Mao, L.7
-
51
-
-
0035863495
-
K-ras and p16 alterations confer poor prognosis in human colorectal cancer
-
Esteller M, Gonzalez S, Risques RA, Marcuello E, Mangues R, Germa JR, Herman JG, Capella G, Peinado MA. K-ras and p16 alterations confer poor prognosis in human colorectal cancer. J. Clin. Oncol. 2001c; 19: 299-304.
-
(2001)
J. Clin. Oncol
, vol.19
, pp. 299-304
-
-
Esteller, M.1
Gonzalez, S.2
Risques, R.A.3
Marcuello, E.4
Mangues, R.5
Germa, J.R.6
Herman, J.G.7
Capella, G.8
Peinado, M.A.9
-
52
-
-
34250784471
-
Dna methylation markers: A versatile diagnostic tool for routine clinical use
-
Lesche R, Eckhardt F. DNA methylation markers: a versatile diagnostic tool for routine clinical use. Curr. Opin. Mol. Ther. 2006; 9: 222-230.
-
(2006)
Curr. Opin. Mol. Ther
, vol.9
, pp. 222-230
-
-
Lesche, R.1
Eckhardt, F.2
-
53
-
-
0033557903
-
Inactivation of the dna repair gene o6-methylguanine-dna methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res. 1999b; 59: 793-797.
-
(1999)
Cancer Res
, vol.59
, pp. 793-797
-
-
Esteller, M.1
Hamilton, S.R.2
Burger, P.C.3
Baylin, S.B.4
Herman, J.G.5
-
54
-
-
0034626988
-
Activity of the dna repair gene mgmt and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, Vanaclocha V et al. Activity of the DNA repair gene MGMT and the clinical response of gliomas to alkylating agents. New Engl. J. Med. 2000a; 343: 1350-1354.
-
(2000)
New Engl. J. Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
Goodman, S.N.4
Hidalgo, O.F.5
Vanaclocha, V.6
-
55
-
-
4143084896
-
Cpg island hypermethylation of the dna repair enzyme methyltransferase predicts response to temozolomide in primarygliomas
-
Paz MF, Yaya-Tur R, Rojas-Marcos I, Reynes G, Pollan M, Aguirre-Cruz L et al. CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primarygliomas. Clin. Cancer Res. 2004; 10(15): 4933-4938.
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.15
, pp. 4933-4938
-
-
Paz, M.F.1
Yaya-Tur, R.2
Rojas-Marcos, I.3
Reynes, G.4
Pollan, M.5
Aguirre-Cruz, L.6
-
56
-
-
33846252663
-
Apop-tosis in malignant glioma cells triggered by the temozolomide-induced dna lesion o6-methylguanine
-
Roos WP, Batista LF, Naumann SC, Wick W, Weller M, Menck CF, Kaina B. Apop-tosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine. Oncogene 2006; 26(2): 186-197.
-
(2006)
Oncogene
, vol.26
, Issue.2
, pp. 186-197
-
-
Roos, W.P.1
Batista, L.F.2
Naumann, S.C.3
Wick, W.4
Weller, M.5
Menck, C.F.6
Kaina, B.7
-
57
-
-
0037869289
-
Role of hmlh1 promoter hypermethylation in drug resistance to 5 fluorouracil in colorectal cancer cell lines
-
Arnold CN, Goel A, Boland CR. Role of hMLH1 promoter hypermethylation in drug resistance to 5 fluorouracil in colorectal cancer cell lines. Int. J. Cancer 2003; 106 (1): 66-73.
-
(2003)
Int. J. Cancer
, vol.106
, Issue.1
, pp. 66-73
-
-
Arnold, C.N.1
Goel, A.2
Boland, C.R.3
-
58
-
-
0033150522
-
Gst function in drug and stress response
-
Tew KD, Ronai Z. GST function in drug and stress response. Drug Resist. Updat. 1999; 2: 143-147.
-
(1999)
Drug Resist. Updat
, vol.2
, pp. 143-147
-
-
Tew, K.D.1
Ronai, Z.2
-
59
-
-
0035807219
-
Inhibition of brca1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the jnk pathway
-
Lafarge S, Sylvain V, Ferrara M, Bignon YJ. Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway. Oncogene 2001; 20: 6597-6606.
-
(2001)
Oncogene
, vol.20
, pp. 6597-6606
-
-
Lafarge, S.1
Sylvain, V.2
Ferrara, M.3
Bignon, Y.J.4
-
60
-
-
0037303184
-
Dna demethylating agents and chromatin-remodelling drugs: Which, how and why
-
Villar-Garea A, Esteller M. DNA demethylating agents and chromatin-remodelling drugs: which, how and why. Curr. Drug. Metabol. 2003; 4: 11-31.
-
(2003)
Curr. Drug. Metabol
, vol.4
, pp. 11-31
-
-
Villar-Garea, A.1
Esteller, M.2
-
61
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004; 429: 457-463.
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
62
-
-
31344475498
-
Inhibitors of dna methylation: Beyond myelodysplastic syndromes
-
Fenaux P. Inhibitors of DNA methylation: beyond myelodysplastic syndromes, Nat. Clin. Pract. Oncol. 2005; 2 (Suppl. 1): S36-S44.
-
(2005)
Nat. Clin. Pract. Oncol
, vol.2
, pp. S36-S44
-
-
Fenaux, P.1
-
63
-
-
21044439177
-
Approval summary: Azacitidine for treatment of myelodysplastic syndrome subtypes
-
Kaminskas E, Farrell A, Abraham S, Baird A, Hsieh LS, Lee SL et al. Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes, Clin. Cancer Res. 2005; 11: 3604-3608.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 3604-3608
-
-
Kaminskas, E.1
Farrell, A.2
Abraham, S.3
Baird, A.4
Hsieh, L.S.5
Lee, S.L.6
-
64
-
-
21244447049
-
Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies
-
Rudek MA, Zhao M, He P, Hartke C, Gilbert J, Gore SD et al. Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies. J. Clin. Oncol. 2005; 23: 3906-3911.
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 3906-3911
-
-
Rudek, M.A.1
Zhao, M.2
He, P.3
Hartke, C.4
Gilbert, J.5
Gore, S.D.6
-
65
-
-
21844444900
-
Changes in promoter methylation and gene expression in patients with mds and mds-aml treated with 5-azacitidine and sodium phenylbutyrate [abstract]
-
Gore SD. Changes in promoter methylation and gene expression in patients with MDS and MDS-AML treated with 5-azacitidine and sodium phenylbutyrate [abstract]. Blood 2004; 104: 469.
-
(2004)
Blood
, vol.104
, pp. 469
-
-
Gore, S.D.1
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