GST function in drug and stress response

Drug Resistance Updates

Volumn 2, Issue 3, 1999, Pages 143-147

  Tew, Kenneth D ^a   Ronai, Ze'ev ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; GLUTATHIONE TRANSFERASE; SULFUR; THIOL GROUP; TUMOR MARKER;

APOPTOSIS; CELL PROLIFERATION; DRUG CONJUGATION; DRUG DETOXIFICATION; DRUG METABOLISM; DRUG RESPONSE; ENZYME ACTIVITY; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHORT SURVEY; STRESS;

EID: 0033150522     PISSN: 13687646     EISSN: None     Source Type: Journal    
DOI: 10.1054/drup.1999.0086     Document Type: Review

References (29)

1. Boyland E., Chasseaud L. F. The role of glutathione and glutathione S-transferases in mercapturic acid biosynthesis. Adv Enzymol Relat Areas Mol Biol. 32:1969;173-219.
2. van Bladeren P. J., van der Gen A., Breimer D. D., Mohn G. R. Stereoselective activation of vicinal dihalogen compounds by glutathione conjugation. Biochem Pharmacol. 28:1979;2521-2524.
3. Litwack G., Ketterer B., Arias I. M. Ligandin: a hepatic protein which binds steroids, bilirubin, carcinogens and a number of exogenous organic anions. Nature. 234:1971;466-467.
4. Tew K. D. Glutathione associated enzymes in anticancer drug resistance. Perspectives in cancer research. Cancer Res. 54:1994;4313-4320.
5. Meyer D. J., Gilmore K. S., Harris J. M., Hartley J. A., Ketterer B. Chlorambucil-monoglutathionyl conjugate is sequestered by human alpha class glutathione S-transferases. Br J Cancer. 66:1992;433-438.
6. Tomarev S. I., Zinovieva R. D. Squid major lens polypeptides are homolgous to glutathione S-transferases subunits. Nature. 336:1988;86-88.
7. Roxas V. P., Smith R. K., Allen E. R., Allen R. D. Overexpression of glutathione S-transferase/ glutathione peroxidase enhances the growth of transgenic tobacco seedlings during stress. Nat Biotechnol. 15:1997;988-991.
8. Lind C., Gerdes R., Schuppe-Koistinen I., Cotgreave I. A. Studies on the mechanism of oxidative modification of human glyceraldehyde-3 phosphate dehydrogenase by glutathione: catalysis by glutaredoxin. Biochem Biophys Res Commun. 247:1998;481-486.
9. Zheng M., Aslund F., Storz G. Activation of the OxyR transcription factor by reversible disulfide bond formation. Science. 279:1998;1718-1721.
10. Paget M. S. B., Kang J. G., Roe J. H., Buttner M. J. SigmaR, an RNA polymerase sigma factor that modulates expression of the thioredoxin system in response to oxidative stress in Streptomyces coelicolor A3(2). EMBO J. 17:1998;5776-5782.
11. Saitoh M., Nishitoh H., Fujii M. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17:1998;2596-2606.
12. Adler V., Yin Z., Fuchs S. Y. Regulation of JNK signaling by GSTp. EMBO J. 18:1999;1321-1334.
13. Lee W-H., Morton R. A., Epstein J. I. Cytidine methylation of regulatory sequences near the π-class glutathione s-transferase gene accompanies human prostatic carcinogenesis. Proc Natl Acad Sci USA. 91:1994;11733-11737.
14. Henderson C. J., Smith A. G., Ure J., Brown K., Bacon E. J., Wolf C. R. Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases. Proc Natl Acad Sci USA. 95:1998;5275-5280.
15. Morgan A. S., Ciaccio P. J., Tew K. D., Kauvar L. M. Isozyme specific GST inhibitors potentiate drug sensitivity in cultured human tumor cell lines. Cancer Chemother Pharmacol. 37:1996;363-370.
16. Kauvar L. M., Morgan A. S., Sanderson P. E., Henner W. D. Glutathione based approaches to improving cancer treatment. Chem-Biol Interact. 111-112:1998;225-238.
17. Peterson J. D., Herzenberg L. A., Vasquez K., Waltenbaugh C. Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns. Proc Natl Acad Sci USA. 95:1998;3071-3076.
18. Herzenberg L. A., DeRosa S. C., Dubs J. G. Glutathione deficiency is associated with impaired survival in HIV disease. Proc Natl Acad Sci USA. 94:1997;1967-1972.
19. Dong C., Yang D. D., Wysk M., Whitmarsh A. J., Davis R. J., Flavell R. A. Defective T cell differentiation in the absence of JNK1. Science. 281:1998;2092-2095.
20. Powis G., Kirkpatrick D. L., Angulo M., Baker A. Thioredoxin redox control of cell growth and death and the effects of inhibitors. Chem Biol Interact. 111-112:1998;23-24.
21. Gotoh Y., Cooper J. A. Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction. J Biol Chem. 273:1998;17477-17482.
22. Makino Y., Yoshikawa N., Okamoto K. Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function. J Biol Chem. 274:1999;3182-3188.
23. Itoh K., Wakabayashi N., Katoh Y. Keap 1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 13:1999;76-86.
24. Alam J., Camhi S., Choi A. M. K. Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcriptional enhancer. J Biol Chem. 270:1995;11977-11984.
25. Ward N. E., Pierce D. S., Chung S. E., Gravitt K. R., O'Brian C. A. Irreversible inactivation of protein kinase C by glutathione. J Biol Chem. 273:1998;12558-12566.
26. Wilhelm D., Bender K., Angel P. The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including jun N-terminal protein kinases and p38 kinase by alkylating agents. Mol Cell Biol. 17:1997;4792-4800.
27. Rainwater R., Parks D., Anderson M. E., Tegtmeyer P., Mann K. Role of cysteine residues in regulation of p53 function. Mol Cell Biol. 15:1995;3892-3903.
28. Liu M., Pelling J. C., Ju J., Chu E., Brash D. E. Antioxidant action via p53-mediated apoptosis. Cancer Res. 58:1998;1723-1729.
29. Shen H., Tsuchida S., Tamai K., Sato K. Identification of cysteine residues involved in disulfide formation in the inactivation of glutathione transferase P-form by hydrogen peroxide. Arch Biochem Biophys. 300:1993;137-141.