Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR

Lancet

Volumn 357, Issue 9265, 2001, Pages 1335-1336

  Evron, Ella ^a   Dooley, William C ^a   Umbricht, Christopher B ^a   Rosenthal, Dorothy ^a   Sacchi, Nicoletta ^a   Gabrielson, Edward ^a   Soito, Angela B ^c   Hung, David T ^c   Ljung, Britt Marie ^b   Davidson, Nancy E ^a   Sukumar, Saraswati ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ProDuct Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D2; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR BETA2; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; BODY FLUID; BREAST CARCINOMA; BREAST DUCT; CANCER DIAGNOSIS; CLINICAL ARTICLE; CONTROLLED STUDY; EARLY DIAGNOSIS; ENDOSCOPY; FEMALE; GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; LAVAGE; MAMMOGRAPHY; METHYLATION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SAMPLE;

EID: 18844470774     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(00)04501-3     Document Type: Article

References (5)

1. Elmore J.G., Barton M.B., Moceri V.M., Polk S., Arena P.J., Fletcher S.W. Ten-year risk of false positive screening mammograms and clinical breast examinations. N Engl J Med. 338:1998;1089-1096.
2. Evron E., Umbricht C.B., Korz D., et al. Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation. Cancer Res. 61:2001;2782-2787.
3. Sirchia S.M., Ferguson A.T., Sironi E., et al. Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells. Oncogene. 19:2000;1556-1563.
4. Herman J.G., Graff J.R., Myohanen S., Nelkin B.D., Baylin S.B. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA. 93:1996;9821-9826.
5. Dooley W.C. Endoscopic visualization of breast tumors. JAMA. 284:2000;1518.