Pyrrolidine dithiocarbamate inhibits translocation of nuclear factor kappa-B in neurons and protects against brain ischaemia with a wide therapeutic time window

Journal of Neurochemistry

Volumn 91, Issue 3, 2004, Pages 755-765

  Nurmi, Antti ^a   Vartiainen, Nina ^a   Pihlaja, Rea ^a   Goldsteins, Gundars ^a   Yrjänheikki, Juha ^b   Koistinaho, Jari ^a,c  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b Cerebricon Limited   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Cytokines; Inflammation; Neuroimmunology; Rodent

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; EXCITOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN INHIBITOR; PYRROLIDINE DITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN NERVE CELL; BRAIN PROTECTION; CELL CULTURE; CONTROLLED STUDY; DNA BINDING; GERBIL; HYPERTENSION; IMMUNOREACTIVITY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN LOCALIZATION; RAT; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; CELLS, CULTURED; CYCLOOXYGENASE 2; CYTOKINES; DISEASE MODELS, ANIMAL; GERBILLINAE; ISCHEMIC ATTACK, TRANSIENT; MALE; MICROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; NF-KAPPA B; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN TRANSPORT; PYRROLIDINES; RATS; RATS, INBRED SHR; RATS, WISTAR; THIOCARBAMATES; TIME FACTORS; TREATMENT OUTCOME;

ANIMALIA; GERBILLINAE; MERIONES UNGUICULATUS; RATTUS NORVEGICUS; RODENTIA;

EID: 7244259205     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02756.x     Document Type: Article

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