Evaluation of CA1 damage using single-voxel 1H-MRS and un-biased stereology: Can non-invasive measures of N-acetyl-asparate following global ischemia be used as a reliable measure of neuronal damage?

Brain Research

Volumn 892, Issue 1, 2001, Pages 166-175

  Sager, Thomas N ^a,d   Topp, Simon ^b   Torup, Lars ^c   Hanson, Lars G ^b   Egestad, Börje ^a   Moller, Arne ^a  

^a NEUROSEARCH A S   (Denmark)

^b HVIDOVRE HOSPITAL   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d H LUNDBECK A S   (Denmark)

Author keywords

Global ischemia; Hippocampus; N acetyl aspartate; Neurodegeneration; Proton magnetic resonance spectroscopy

Indexed keywords

N ACETYLASPARTIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; ARTERY OCCLUSION; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CAROTID ARTERY; CELL DENSITY; CONTROLLED STUDY; CORRELATION FUNCTION; DIAGNOSTIC ACCURACY; EVALUATION; GERBIL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; HISTOLOGY; MALE; NERVE CELL; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANIMALS; ASPARTIC ACID; BIOLOGICAL MARKERS; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GERBILLINAE; HIPPOCAMPUS; HYDROGEN; ISCHEMIC ATTACK, TRANSIENT; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NEURONS; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

EID: 0035895819     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)03274-1     Document Type: Article

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