Global forebrain ischemia results in differential cellular expression of interleukin-1β (IL-1β) and its receptor at mRNA and protein level

Journal of Cerebral Blood Flow and Metabolism

Volumn 17, Issue 10, 1997, Pages 1107-1120

  Sairanen, Tiina R ^a   Lindsberg, Perttu J ^a   Brenner, Michael ^b   Sirén, Anna Leena ^a   Vidman, Tiina R ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Global ischemia; Immunohistochemistry; In situ hybridization; Interleukin 1 receptor (Type I); Interleukin 1 ; Rats

Indexed keywords

INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; MESSENGER RNA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CAUDATE NUCLEUS; CONTROLLED STUDY; FOREBRAIN; GENE EXPRESSION; HIPPOCAMPUS; HISTOPATHOLOGY; HYPOTENSION; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PUTAMEN; RAT; RNA ANALYSIS; TISSUE DISTRIBUTION;

EID: 0030729296     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199710000-00013     Document Type: Article

References (37)

1. Ban E, Milon G, Prudhomme N, Fillion G, Haour F (1991) Receptors for interleukin-1 (α and β) in mouse brain: Mapping and neuronal localization in hippocampus. Neuroscience 43:21-30
2. Bandtlow C, Meyer M, Lindholm D, Spranger M, Heumann R, Thoenen H (1990) Regional and cellular codistribution of interleukin 1β and nerve growth factor mRNA in the adult rat brain: Possible relationship to the regulation of nerve growth factor synthesis. J Cell Biol 111:1701-1711
3. Benveniste E (1992) Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action. Am J Physiol 32:C1-16
4. Betz AL, Yang G-Y, Davidson B (1995) Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J Cereb Blood Flow Metab 15:547-551
5. Breder CD, Dinarello CA, Saper CB (1988) Interleukin-1 Immunoreactive Innervation of the Human Hypothalamus. Science 240:321-323
6. Cunningham E, Jr., Wada E, Carter D, Tracey D, Battey J, De Souza E (1992) In situ histochemical localization of type 1 interleukin-1 receptor messenger RNA in the central nervous system, pituitary, and adrenal gland of the mouse. J Neurosci 12:1101-1114
7. Dinarello CA (1991) Interleukin-1 and interleukin-1 antagonism. Blood 77:1627-1652
8. Farrar W, Kilian P, Ruff M, Hill J, Pert C (1987) Visualization and characterization of interleukin 1 receptors in brain. J Immunol 139:459-463
9. Garcia JH, Liu KF, Relton JK (1995) Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion. Am J Pathol 147:1477-1486
10. Gerfen C (1989) Quantification of in situ hybridization histochemistry for analysis of brain function. In: Methods in Neurosciences, vol 1: Gene Probes (Conn PM, ed), San Diego, Academic Press, pp 79-97
11. Hallenbeck JM (1994) Blood-damaged tissue interaction in experimental brain ischemia. Acta Neurochir Suppl 60:233-237
12. Hallenbeck JM, Dutka AJ (1990) Background Review and Current Concepts of Reperfusion Injury. Arch Neurol 47:1245-1254
13. Haour F, Ban E, Milon G, Baran D, Fillion G (1990) Brain interleukin 1 receptors: characterization and modulation after lipopolysaccharide injection. Prog Neuro Endocrin Immunol 3:196-204
14. Hopkins S, Rothwell N (1995) Cytokines and the nervous system I: expression and recognition. Trends Neurosci 18:83-88
15. Katsuura G, Gottschall P, Arimura A (1988) Identification of a high-affinity receptor for interleukin-1 beta in rat brain. Biochem Biophys Res Commun 156:61-67
16. Kirino T (1982) Delayed neuronal death in the gerbil hippocampus following transient ischemia. Brain Res 239:57-69
17. Lechan RM, Toni R, Clark BD, Cannon JG, Shaw AR, Dinarello CA, Reichlin S (1990) Immunoreactive interleukin-1β localization in the rat forebrain Brain Res 514:135-140
18. Licinio J, Wong M, Gold P (1991) Localization of interleukin-1 receptor antagonist mRNA in rat brain. Endocrinology 129:562-564
19. Lindsberg PJ, Frerichs KU, Burris JA, Hallenbeck JM, Feuerstein G (1991) Cortical microcirculation in a new model of focal laser-induced secondary brain damage. J Cereb Blood Flow Metab 11: 88-98
20. Liu T, McDonnell PC, Young PR, White RF, Sirén AL, Hallenbeck JM, Barone FC, Feuerstein GZ (1993) Interleukin-1β mRNA expression in ischemic rat cortex. Stroke 24:1746-1751
21. Liu T, Clark RK, McDonnell PC, Young PR, White RF, Barone FC, Feuerstein GZ (1994) Tumor necrosis factor-α expression in ischemic neurons. Stroke 25:1481-1488
22. Matsuyama T, Mischishita H, Nakamura H, Tsuchiyama, Shimizu S, Watanabe K, Sugita M (1993) Induction of copper-zinc dismutase in gerbil hippocampus after ischemia. J Cereb Blood Flow Metab 13:135-144
23. Minami M, Kuraishi Y, Yabuuchi K, Yamazaki A, Satoh M (1992) Induction of interleukin-1 β mRNA in rat brain after transient forebrain ischemia. J Neurochem 58:390-392
24. Relton JK, Rothwell NJ (1992) Interleukin-1 receptor antagonist inhibits ischaemic and exitotoxic neuronal damage in the rat. Brain Res 29:243-246
25. Rothwell NJ (1991) Functions and mechanisms of interleukin 1 in the brain. Trends Pharmacol Sci 12:430-436
26. Schindler R, Gelfand JA, Dinarello CA (1990a) Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself. Blood 76:1632-1638
27. Satoi K, Suyama K, Nishida K, Sei Y, Basile AS (1996) Early increase in TNF-α, IL-6, and IL-1β levels following transient cerebral ischemia in gerbil brain. Neurosci Lett 206:149-152
28. Schindler R, Clark BD, Dinarello CA (1990b) Dissociation between interleukin-1β mRNA and protein synthesis in human peripheral blood mononuclear cells. J Biol Chem 265:10232-10237
29. Siesjö BK, Katsura K-I, Zhao Q, Folbergrova J, Pahlmark K, Siesjö P, Smith M-L (1995) Mechanisms of secondary brain damage in global and focal ischemia: A speculative synthesis. J Neurotrauma 12:943-956
30. Smith ML, Bendek G, Dahlgren N, Rosen I, Wieloch T, Siesjö BK (1984) Models for studying long-term recovery following forebrain ischemia in the rat. 2. A-vessel occlusion model. Acta Neurol Scand 69:385-401
31. Szaflarski J, Burtrum D, Silverstein F (1995) Cerebral hypoxiaischemia stimulates cytokine gene expression in perinatal rats. Stroke 26:1093-1100
32. Takao T, Tracey D, Mitchell M, De Souza E: Interleukin-1 receptors in mouse brain (1990) Characterization and neuronal localization. Endocrinology 127:3070-3078
33. Wang X, Yue TL, Barone F, White R, Gagnon R, Feuerstein G (1994) Concomitant cortical expression of TNF-α and IL-1β mRNA:s follows early response gene expression in transient focal ischemia. Mol Chem Neuropathol 23:103-114
34. Wiessner C, Gehrmann J, Lindholm D, Topper R, Kreutzberg G, Hossmann K (1993) Expression of transforming growth factor 1 and interleukin-1β mRNA in rat brain following transient forebrain ischemia. Acta Neuropathol 86:439-446
35. Yabuuchi K, Minami M, Katsumata S, Yamazaki A, Satoh M (1994) An in situ hybridization study on interleukin-1β mRNA induced by transient forebrain ischemia in the rat brain. Mol Brain Res 26: 135-142
36. Yamasaki Y, Suzuki T, Yamaya H, Matsuura N, Onodera H, Kogure K (1992) Possible involvement of interleukin-1 in ischemic brain edema formation. Neurosci Lett 142:45-47
37. Yamasaki Y, Matsuura N, Shozuhara H, Onodera H, Itoyama Y, Kogure K (1995) Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke 26:676-681