메뉴 건너뛰기




Volumn 5, Issue 5, 1999, Pages 554-559

NF-κB is activated and promotes cell death in focal, cerebral ischemia

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR RELA;

EID: 0032587072     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/8432     Document Type: Article
Times cited : (611)

References (46)
  • 1
    • 0030911057 scopus 로고    scopus 로고
    • The international stroke trial (IST): A randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischemic stroke
    • International stroke trial collaborative group. The international stroke trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischemic stroke. Lancet 349, 1569-1581 (1997).
    • (1997) Lancet , vol.349 , pp. 1569-1581
  • 2
    • 0029038416 scopus 로고
    • Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat
    • Li, Y. et al. Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat. Am. J. Pathol. 146, 1045-1051 (1995).
    • (1995) Am. J. Pathol. , vol.146 , pp. 1045-1051
    • Li, Y.1
  • 3
    • 0032525260 scopus 로고    scopus 로고
    • Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia
    • Namura, S. et al. Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J. Neurosci. 18, 3659-3668 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 3659-3668
    • Namura, S.1
  • 4
    • 0031892704 scopus 로고    scopus 로고
    • Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family
    • Endres, M. et al. Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family. J. Cereb. Blood Flow Metab. 18, 238-247 (1998).
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 238-247
    • Endres, M.1
  • 5
    • 0030898311 scopus 로고    scopus 로고
    • Apoptosis: Activate NF-κB or die ?
    • Baichwal, V.R. & Baeuerle, P.A. Apoptosis: Activate NF-κB or die ? Curr. Biol. 7, R94-96 (1997).
    • (1997) Curr. Biol. , vol.7
    • Baichwal, V.R.1    Baeuerle, P.A.2
  • 6
    • 0031172065 scopus 로고    scopus 로고
    • NF-κB: A crucial transcription factor for glial and neuronal cell function
    • O'Neill, L.A. & Kaltschmidt, C. NF-κB: a crucial transcription factor for glial and neuronal cell function. Trends Neurosci. 20, 252-258 (1997).
    • (1997) Trends Neurosci. , vol.20 , pp. 252-258
    • O'Neill, L.A.1    Kaltschmidt, C.2
  • 8
    • 0029666306 scopus 로고    scopus 로고
    • NF-κB activity in transgenic mice: Developmental regulation and tissue specificity
    • Schmidt-Ullrich, R. et al. NF-κB activity in transgenic mice: developmental regulation and tissue specificity. Development 122, 2117-2128 (1996).
    • (1996) Development , vol.122 , pp. 2117-2128
    • Schmidt-Ullrich, R.1
  • 9
    • 0028981287 scopus 로고
    • Synaptic activation of NF-κB by glutamate in cerebellar granule neurons in vitro
    • Guerrini, L., Blasi, F. & Denis-Donini, S. Synaptic activation of NF-κB by glutamate in cerebellar granule neurons in vitro. Proc. Natl. Acad. Sci. USA 92, 9077-9081 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9077-9081
    • Guerrini, L.1    Blasi, F.2    Denis-Donini, S.3
  • 10
    • 0030017136 scopus 로고    scopus 로고
    • Seizure activity results in a rapid induction of NF-κB in adult but not juvenile rat limbic structures
    • Rong, Y. & Baudry, M. Seizure activity results in a rapid induction of NF-κB in adult but not juvenile rat limbic structures. J. Neurochem. 67, 662-668 (1996).
    • (1996) J. Neurochem. , vol.67 , pp. 662-668
    • Rong, Y.1    Baudry, M.2
  • 11
    • 0028889739 scopus 로고
    • Stimulation of ionotropic glutamate receptors activates transcription factor NF-κB in primary neurons
    • Kaltschmidt, C., Kaltschmidt, B. & Baeuerle, P.A. Stimulation of ionotropic glutamate receptors activates transcription factor NF-κB in primary neurons. Proc. Natl. Acad. Sci. USA 92, 9618-9622 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9618-9622
    • Kaltschmidt, C.1    Kaltschmidt, B.2    Baeuerle, P.A.3
  • 12
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle, P. & Henkel, T. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12, 141-179 (1994).
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141-179
    • Baeuerle, P.1    Henkel, T.2
  • 13
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • Baldwin, A.S.J. The NF-κB and IκB proteins: New discoveries and insights. Annu. Rev. Immunol 14, 649-681 (1996).
    • (1996) Annu. Rev. Immunol , vol.14 , pp. 649-681
    • Baldwin, A.S.J.1
  • 14
    • 0027521432 scopus 로고
    • Distinct NF-κB/Rel transcription factors are responsible for tissue-specific and inducible gene activation
    • Lernbecher, T., Müller, U. & Wirth, T. Distinct NF-κB/Rel transcription factors are responsible for tissue-specific and inducible gene activation. Nature 365, 767-770 (1993).
    • (1993) Nature , vol.365 , pp. 767-770
    • Lernbecher, T.1    Müller, U.2    Wirth, T.3
  • 15
    • 0029079396 scopus 로고
    • Dominant-negative action of the jimpy mutation in mice complemented with an autosomal transgene for myelin proteolipid protein
    • Schneider, A., Griffiths, I.R., Readhead, C. & Nave, K.-A. Dominant-negative action of the jimpy mutation in mice complemented with an autosomal transgene for myelin proteolipid protein. Proc. Natl. Acad. Sci. USA 92, 4447-4451 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4447-4451
    • Schneider, A.1    Griffiths, I.R.2    Readhead, C.3    Nave, K.-A.4
  • 17
    • 0031439697 scopus 로고    scopus 로고
    • Monofilament intraluminal middle cerebral artery occlusion in the mouse
    • Clark, W.M., Lessov, N.S., Dixon, M.P. & Eckenstein, F. Monofilament intraluminal middle cerebral artery occlusion in the mouse. Neurol. Res. 19, 641-648 (1997).
    • (1997) Neurol. Res. , vol.19 , pp. 641-648
    • Clark, W.M.1    Lessov, N.S.2    Dixon, M.P.3    Eckenstein, F.4
  • 18
    • 0029839695 scopus 로고    scopus 로고
    • Middle cerebral artery occlusion in the rat by intraluminal suture
    • Belayev, L., Alonso, O.F., Busto, R., Zhao, W. & Ginsberg, M.D. Middle cerebral artery occlusion in the rat by intraluminal suture. Stroke 27, 1616-1623 (1996).
    • (1996) Stroke , vol.27 , pp. 1616-1623
    • Belayev, L.1    Alonso, O.F.2    Busto, R.3    Zhao, W.4    Ginsberg, M.D.5
  • 19
    • 0028804551 scopus 로고
    • Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses
    • Sha, W.C., Liou, H.-C., Tuomanen, E.I. & Baltimore, D. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell 80, 321-330 (1995).
    • (1995) Cell , vol.80 , pp. 321-330
    • Sha, W.C.1    Liou, H.-C.2    Tuomanen, E.I.3    Baltimore, D.4
  • 20
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • Lipton, S.A. & Rosenberg, P.A. Excitatory amino acids as a final common pathway for neurologic disorders. N. Engl. J. Med. 330, 613-22 (1994).
    • (1994) N. Engl. J. Med. , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 21
    • 0030581738 scopus 로고    scopus 로고
    • Flupirtine increases the levels of glutathione and Bcl-2 in hNT (human Ntera/D1) neurons: Mode of action of the drug-mediated anti-apoptotic effect
    • Perovic, S., Pialoglou, P., Schröder, H.C., Pergande, G. & Müller, W.E.G. Flupirtine increases the levels of glutathione and Bcl-2 in hNT (human Ntera/D1) neurons: mode of action of the drug-mediated anti-apoptotic effect. Eur. J. Pharmacol. 317, 157-164 (1996).
    • (1996) Eur. J. Pharmacol. , vol.317 , pp. 157-164
    • Perovic, S.1    Pialoglou, P.2    Schröder, H.C.3    Pergande, G.4    Müller, W.E.G.5
  • 23
    • 0032014073 scopus 로고    scopus 로고
    • DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1
    • Kasibathla, S. et al. DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1. Mol. Cell 1, 543-551 (1998).
    • (1998) Mol. Cell , vol.1 , pp. 543-551
    • Kasibathla, S.1
  • 24
    • 0345157654 scopus 로고    scopus 로고
    • CD-95-Ligand (Fas-Ligand/ APO-1 L) and TRAIL mediate ischemia-induced apoptosis in neurons
    • in the press
    • Martin-Villalba, A. et al. CD-95-Ligand (Fas-Ligand/ APO-1 L) and TRAIL mediate ischemia-induced apoptosis in neurons. J. Neurosci. (in the press).
    • J. Neurosci.
    • Martin-Villalba, A.1
  • 25
    • 0030983079 scopus 로고    scopus 로고
    • Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease
    • Kaltschmidt, B., Uherek, M., Volk, B., Baeuerle, P.A. & Kaltschmidt, C. Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA 94, 2642-2647 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2642-2647
    • Kaltschmidt, B.1    Uherek, M.2    Volk, B.3    Baeuerle, P.A.4    Kaltschmidt, C.5
  • 26
    • 0032510692 scopus 로고    scopus 로고
    • Amyloid β-peptide stimulates nitric oxide production in astrocytes through an NF-κB-dependent mechanism
    • Akama, K.T., Albanese, C., Pestell, R.G. & VanEldik, L.J. Amyloid β-peptide stimulates nitric oxide production in astrocytes through an NF-κB-dependent mechanism. Proc. Natl. Acad. Sci. USA 95, 5795-5800 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5795-5800
    • Akama, K.T.1    Albanese, C.2    Pestell, R.G.3    VanEldik, L.J.4
  • 27
    • 0030842085 scopus 로고    scopus 로고
    • Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with parkinson disease
    • Hunot, S. et al. Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with parkinson disease. Proc. Natl. Acad. Sci. USA 94, 7531-7536 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7531-7536
    • Hunot, S.1
  • 28
    • 0029869593 scopus 로고    scopus 로고
    • Selective activation of NF-κB by nerve growth factor through the neurotrophin receptor p75
    • Carter, B.D. et al. Selective activation of NF-κB by nerve growth factor through the neurotrophin receptor p75. Science 272, 542-545 (1996).
    • (1996) Science , vol.272 , pp. 542-545
    • Carter, B.D.1
  • 29
    • 0031943498 scopus 로고    scopus 로고
    • Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of NF-κB in rats
    • Clemens, J.A. et al. Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of NF-κB in rats. Stroke 29, 677-682 (1998).
    • (1998) Stroke , vol.29 , pp. 677-682
    • Clemens, J.A.1
  • 30
    • 0029799831 scopus 로고    scopus 로고
    • Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation
    • Grilli, M., Pizzi, M., Memo, M. & Spano, P. Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation. Science 274, 1383-1385 (1996).
    • (1996) Science , vol.274 , pp. 1383-1385
    • Grilli, M.1    Pizzi, M.2    Memo, M.3    Spano, P.4
  • 31
    • 0031938280 scopus 로고    scopus 로고
    • Nuclear factor-κB contributes to excitotoxin-induced apoptosis in rat striatum
    • Qin, Z.H., Wang, Y., Nakai, M. & Chase, T.N. Nuclear factor-κB contributes to excitotoxin-induced apoptosis in rat striatum. Mol. Pharmacol. 53, 33-42 (1998).
    • (1998) Mol. Pharmacol. , vol.53 , pp. 33-42
    • Qin, Z.H.1    Wang, Y.2    Nakai, M.3    Chase, T.N.4
  • 32
    • 0030611750 scopus 로고    scopus 로고
    • Activation of NF-kB protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration
    • Mattson, M.P., Goodman, Y., Luo, H., Fu, W. & Furukawa, K. Activation of NF-kB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration. J. Neurosci. Res. 49, 681-697 (1997).
    • (1997) J. Neurosci. Res. , vol.49 , pp. 681-697
    • Mattson, M.P.1    Goodman, Y.2    Luo, H.3    Fu, W.4    Furukawa, K.5
  • 33
    • 0032080328 scopus 로고    scopus 로고
    • High constitutive NF-κB activity mediates resistance to oxidative stress in neuronal cells
    • Lezoualc'h, F., Sagara, Y., Holsboer, F. & Behl, C. High constitutive NF-κB activity mediates resistance to oxidative stress in neuronal cells. J. Neurosci. 18, 3224-3232 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 3224-3232
    • Lezoualc'h, F.1    Sagara, Y.2    Holsboer, F.3    Behl, C.4
  • 34
    • 0031022142 scopus 로고    scopus 로고
    • Janus faces of NF-κB: Neurodestruction versus neuroprotection
    • Lipton, S.A. Janus faces of NF-κB: Neurodestruction versus neuroprotection. Nature Med. 3, 20-22 (1997).
    • (1997) Nature Med. , vol.3 , pp. 20-22
    • Lipton, S.A.1
  • 35
    • 0028167846 scopus 로고
    • Inhibition of NF-κB by sodium salicylate and aspirin
    • Kopp, E. & Ghosh, S. Inhibition of NF-κB by sodium salicylate and aspirin. Science 265, 956-959 (1994).
    • (1994) Science , vol.265 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 36
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of NF-κB activation in intact cells
    • Schreck, R., Meier, B., Männel, D., Dröge, W. & Baeuerle, P.A. Dithiocarbamates as potent inhibitors of NF-κB activation in intact cells. J. Exp. Med. 175, 1181-1194 (1992).
    • (1992) J. Exp. Med. , vol.175 , pp. 1181-1194
    • Schreck, R.1    Meier, B.2    Männel, D.3    Dröge, W.4    Baeuerle, P.A.5
  • 37
    • 0029983730 scopus 로고    scopus 로고
    • The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
    • Beyaert, R. et al. The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. EMBO J. 15, 1914-1923 (1996).
    • (1996) EMBO J. , vol.15 , pp. 1914-1923
    • Beyaert, R.1
  • 38
    • 0031749682 scopus 로고    scopus 로고
    • Redox gene therapy for ischemia / reperfusion injury of the liver reduces AP1 and NF-κB activation
    • Zwacka, R.M. et al. Redox gene therapy for ischemia / reperfusion injury of the liver reduces AP1 and NF-κB activation. Nature Med. 4, 698-704 (1998).
    • (1998) Nature Med. , vol.4 , pp. 698-704
    • Zwacka, R.M.1
  • 39
    • 0030855813 scopus 로고    scopus 로고
    • In vivo transfection of cis element 'decoy' against nuclear NF-κB binding site prevents myocardial infarction
    • Morishita, R. et al. In vivo transfection of cis element 'decoy' against nuclear NF-κB binding site prevents myocardial infarction. Nature Med. 3, 894-899 (1997).
    • (1997) Nature Med. , vol.3 , pp. 894-899
    • Morishita, R.1
  • 40
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
    • Neurath, M.F., Pettersson, S., Meyer zum Buschenfelde, K.H. & Strober, W. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice. Nature Med. 2, 998-1004 (1996).
    • (1996) Nature Med. , vol.2 , pp. 998-1004
    • Neurath, M.F.1    Pettersson, S.2    Meyer Zum Buschenfelde, K.H.3    Strober, W.4
  • 41
    • 0030060152 scopus 로고    scopus 로고
    • Procedural and strain-related variables significantly affect outcome in a murine model of focal cerebral ischemia
    • Connolly, E.S., Winfree, C.J., Stern, D.M., Solomon, R.A. & Pinsky, D.J. Procedural and strain-related variables significantly affect outcome in a murine model of focal cerebral ischemia. Neurosurgery 38, 523-531 (1996).
    • (1996) Neurosurgery , vol.38 , pp. 523-531
    • Connolly, E.S.1    Winfree, C.J.2    Stern, D.M.3    Solomon, R.A.4    Pinsky, D.J.5
  • 42
    • 0027263342 scopus 로고
    • Mouse strain differences in susceptibility to cerebral ischemia are related to cerebral vascular anatomy
    • Barone, F.C., Knudsen, D.J., Nelson, A.H., Feuerstein, G.Z. & Willette, R.N. Mouse strain differences in susceptibility to cerebral ischemia are related to cerebral vascular anatomy. J. Cereb. Blood Flow Metab. 13, 683-692 (1993).
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 683-692
    • Barone, F.C.1    Knudsen, D.J.2    Nelson, A.H.3    Feuerstein, G.Z.4    Willette, R.N.5
  • 43
    • 0344295249 scopus 로고    scopus 로고
    • Early delineation of ischemic tissue in rat brain cryosections by high contrast staining
    • in the press
    • Vogel, J., Mobius, C. & Kuschinsky, W. Early delineation of ischemic tissue in rat brain cryosections by high contrast staining. Stroke (in the press).
    • Stroke
    • Vogel, J.1    Mobius, C.2    Kuschinsky, W.3
  • 44
    • 0025228733 scopus 로고
    • A semiautomated method for measuring brain infarct volume
    • Swanson, R.A. et al. A semiautomated method for measuring brain infarct volume. J. Cereb. Blood Flow Metab. 10, 290-293 (1990).
    • (1990) J. Cereb. Blood Flow Metab. , vol.10 , pp. 290-293
    • Swanson, R.A.1
  • 45
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J., Lebovitz, R. & Roeder, R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11, 1475-1489 (1983).
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.1    Lebovitz, R.2    Roeder, R.G.3
  • 46
    • 0028152894 scopus 로고
    • Constitutive and inducible Rel/NF-κB activities in mouse thymus and spleen
    • Weih, F., Carrasco, D. & Bravo, R. Constitutive and inducible Rel/NF-κB activities in mouse thymus and spleen. Oncogene 9, 3289-3297 (1994).
    • (1994) Oncogene , vol.9 , pp. 3289-3297
    • Weih, F.1    Carrasco, D.2    Bravo, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.