메뉴 건너뛰기




Volumn 159, Issue 8, 1997, Pages 3976-3983

In Vivo Inhibition of Nuclear Factor-κB Activation Prevents Inducible Nitric Oxide Synthase Expression and Systemic Hypotension in a Rat Model of Septic Shock

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; THIOCARBAMIC ACID DERIVATIVE;

EID: 0031572429     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (232)

References (43)
  • 2
    • 0028270719 scopus 로고
    • Regulation of biosynthesis of nitric oxide
    • Nathan, C., and Q. W. Xie. 1994. Regulation of biosynthesis of nitric oxide. J. Biol. Chem. 269:13725.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13725
    • Nathan, C.1    Xie, Q.W.2
  • 3
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada, S., R. M. J. Palmer, and E. A. Higgs. 1991. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43:109.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 4
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan, C. 1992. Nitric oxide as a secretory product of mammalian cells. FASEB J. 6:3051.
    • (1992) FASEB J. , vol.6 , pp. 3051
    • Nathan, C.1
  • 8
    • 0027431656 scopus 로고
    • Lipopolysaccharide treatment in vivo induces widespread tissue expression of inducible nitric oxide synthase mRNA
    • Liu, S. F., I. M. Adcock, R. W. Old, P. J. Barnes, and T. W. Evans. 1993. Lipopolysaccharide treatment in vivo induces widespread tissue expression of inducible nitric oxide synthase mRNA. Biochem. Biophys. Res. Commun. 196: 1208.
    • (1993) Biochem. Biophys. Res. Commun. , vol.196 , pp. 1208
    • Liu, S.F.1    Adcock, I.M.2    Old, R.W.3    Barnes, P.J.4    Evans, T.W.5
  • 10
    • 0026346162 scopus 로고
    • Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock
    • Petros, A., D. Bennett, and P. Vallance. 1991. Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock. Lancet 338:1557.
    • (1991) Lancet , vol.338 , pp. 1557
    • Petros, A.1    Bennett, D.2    Vallance, P.3
  • 11
    • 0028924241 scopus 로고
    • In vivo treatment with endotoxin induces nitric oxide synthase in rat main pulmonary artery
    • Griffiths, M. J., S. F. Liu, N. P. Curzen, M. Messent, and T. W. Evans. 1995. In vivo treatment with endotoxin induces nitric oxide synthase in rat main pulmonary artery. Am. J. Physiol. 268:L509.
    • (1995) Am. J. Physiol. , vol.268
    • Griffiths, M.J.1    Liu, S.F.2    Curzen, N.P.3    Messent, M.4    Evans, T.W.5
  • 13
    • 0027920980 scopus 로고
    • Pathogenetic mechanisms of septic shock
    • Parrillo, J. E. 1993. Pathogenetic mechanisms of septic shock. N. Engl. J. Med. 328:1471.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1471
    • Parrillo, J.E.1
  • 15
    • 0028174061 scopus 로고
    • Function and activation of NF-κ B in the immune system
    • Baeuerle, P. A., and T. Henkel. 1994. Function and activation of NF-κ B in the immune system. Annu. Rev. Immunol. 12:141.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141
    • Baeuerle, P.A.1    Henkel, T.2
  • 17
    • 0028850008 scopus 로고
    • The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase: Activation by nuclear factor-κ B
    • Spink, J., S. Cohen, and T. J. Evans. 1995. The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase: activation by nuclear factor-κ B. J. Biol. Chem. 270:29541.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29541
    • Spink, J.1    Cohen, S.2    Evans, T.J.3
  • 18
    • 0027939931 scopus 로고
    • Role of transcription factor NF-κ B/Rel in induction of nitric oxide synthase
    • Xie, Q., Y. Kashiwabara, and C. Nathan. 1994. Role of transcription factor NF-κ B/Rel in induction of nitric oxide synthase. J. Biol. Chem. 269:4705.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4705
    • Xie, Q.1    Kashiwabara, Y.2    Nathan, C.3
  • 19
    • 0029666268 scopus 로고    scopus 로고
    • Suppression of interleukin-1β-induced nitric-oxide synthase promoter/enhancer activity by transforming growth factor-1β in vascular smooth muscle cells: Evidence for mechanisms other than NF-κB
    • Perrella, M. A., C. Patterson, L. Tan, S. F. Yet, C. M. Hsieh, M. Yoshizumi, and M. E. Lee. 1996. Suppression of interleukin-1β-induced nitric-oxide synthase promoter/enhancer activity by transforming growth factor-1β in vascular smooth muscle cells: evidence for mechanisms other than NF-κB. J. Biol. Chem. 271: 13776.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13776
    • Perrella, M.A.1    Patterson, C.2    Tan, L.3    Yet, S.F.4    Hsieh, C.M.5    Yoshizumi, M.6    Lee, M.E.7
  • 21
    • 0030586689 scopus 로고    scopus 로고
    • In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation
    • Blackwell, T. S., T. R. Blackwell, E. P. Holden, B. W. Christman, and J. W. Christman. 1996. In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation. J. Immunol. 157:1630.
    • (1996) J. Immunol. , vol.157 , pp. 1630
    • Blackwell, T.S.1    Blackwell, T.R.2    Holden, E.P.3    Christman, B.W.4    Christman, J.W.5
  • 22
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells
    • Schreck, R., B. Meier, D. N. Mannel, W. Droge, and P. A. Baeuerle. 1992. Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J. Exp. Med. 175:1181.
    • (1992) J. Exp. Med. , vol.175 , pp. 1181
    • Schreck, R.1    Meier, B.2    Mannel, D.N.3    Droge, W.4    Baeuerle, P.A.5
  • 23
    • 0028906502 scopus 로고
    • Pyrrolidine dithiocarbamate inhibits intercellular adhesion molecule-1 biosynthesis induced by cytokines in human fibroblasts
    • Kawai, M., R. Nishikomori, E. Y. Jung, G. Tai, C. Yamanaka, M. Mayumi, and T. Heike. 1995. Pyrrolidine dithiocarbamate inhibits intercellular adhesion molecule-1 biosynthesis induced by cytokines in human fibroblasts. J. Immunol. 154: 2333.
    • (1995) J. Immunol. , vol.154 , pp. 2333
    • Kawai, M.1    Nishikomori, R.2    Jung, E.Y.3    Tai, G.4    Yamanaka, C.5    Mayumi, M.6    Heike, T.7
  • 25
    • 0029929872 scopus 로고    scopus 로고
    • Antioxidants inhibit interleukin-1-induced cyclooxygenase and nitric-oxide synthase expression in rat mesangial cells: Evidence for post-transcriptional regulation
    • Tetsuka, T., L. D. Baier, and A. R. Morrison. 1996. Antioxidants inhibit interleukin-1-induced cyclooxygenase and nitric-oxide synthase expression in rat mesangial cells: evidence for post-transcriptional regulation. J. Biol. Chem. 271: 11689.
    • (1996) J. Biol. Chem. , vol.271 , pp. 11689
    • Tetsuka, T.1    Baier, L.D.2    Morrison, A.R.3
  • 26
    • 0027365599 scopus 로고
    • Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
    • Marui, N., M. K. Offermann, R. Swerlick, C. Kunsch, C. A. Rosen, M. Ahmad, R. W. Alexander, and R. M. Medford. 1993. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J. Clin. Invest. 92:1866.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1866
    • Marui, N.1    Offermann, M.K.2    Swerlick, R.3    Kunsch, C.4    Rosen, C.A.5    Ahmad, M.6    Alexander, R.W.7    Medford, R.M.8
  • 27
    • 0029959753 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate inhibits the production of interleukin-6, interleukin-8, and granulocyte-macrophage colony-stimulating factor by human endothelial cells in response to inflammatory mediators: Modulation of NF-κB and AP-1 transcription factors activity
    • Munoz, C., D. Pascual-Salcedo, M. C Castellanos, A. Alfranca, J. Aragones, A. Vara, M. J. Redondo, and M. O. de Landazuri. 1996. Pyrrolidine dithiocarbamate inhibits the production of interleukin-6, interleukin-8, and granulocyte-macrophage colony-stimulating factor by human endothelial cells in response to inflammatory mediators: modulation of NF-κB and AP-1 transcription factors activity. Blood 88:3482.
    • (1996) Blood , vol.88 , pp. 3482
    • Munoz, C.1    Pascual-Salcedo, D.2    Castellanos, M.C.3    Alfranca, A.4    Aragones, J.5    Vara, A.6    Redondo, M.J.7    De Landazuri, M.O.8
  • 29
    • 0029737558 scopus 로고    scopus 로고
    • A diet containing glycine improves survival in endotoxin shock in the rat
    • Ikejima, K., Y. Iimuro, D. T. Forman, and R. G. Thurman. 1996. A diet containing glycine improves survival in endotoxin shock in the rat. Am. J. Physiol. 271:G97.
    • (1996) Am. J. Physiol. , vol.271
    • Ikejima, K.1    Iimuro, Y.2    Forman, D.T.3    Thurman, R.G.4
  • 33
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
    • (1987) Anal. Biochem. , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 34
    • 0022423216 scopus 로고
    • Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family
    • Fort, P., L. Marty, M. Piechaczyk, S. El Sabrouty, C. Dani, P. Jeanteur, and J. M. Blanchard. 1985. Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res. 13:1431.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 1431
    • Fort, P.1    Marty, L.2    Piechaczyk, M.3    El Sabrouty, S.4    Dani, C.5    Jeanteur, P.6    Blanchard, J.M.7
  • 35
    • 0030935693 scopus 로고    scopus 로고
    • Time course and cellular localization of lipopolysaccharide-induced inducible nitric oxide synthase messenger RNA expression in the rat in vivo
    • Liu, S. F., P. J. Barnes, and T. W. Evans. 1997. Time course and cellular localization of lipopolysaccharide-induced inducible nitric oxide synthase messenger RNA expression in the rat in vivo. Crit. Care Med. 25:512.
    • (1997) Crit. Care Med. , vol.25 , pp. 512
    • Liu, S.F.1    Barnes, P.J.2    Evans, T.W.3
  • 36
    • 0029786764 scopus 로고    scopus 로고
    • Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells
    • Khan, B. V., D. G. Harrison, M. T. Olbrych, R. W. Alexander, and R. M. Medford. 1996. Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells. Proc. Natl. Acad. Sci. USA 93:114.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 114
    • Khan, B.V.1    Harrison, D.G.2    Olbrych, M.T.3    Alexander, R.W.4    Medford, R.M.5
  • 37
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation: Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina, R., P. Libby, H. B. Peng, V. J. Thannickal, T. B. Rajavashisth, M. A. Gimbrone, Jr., W. S. Shin, and J. K. Liao. 1995. Nitric oxide decreases cytokine-induced endothelial activation: nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J. Clin. Invest. 96:60.
    • (1995) J. Clin. Invest. , vol.96 , pp. 60
    • De Caterina, R.1    Libby, P.2    Peng, H.B.3    Thannickal, V.J.4    Rajavashisth, T.B.5    Gimbrone Jr., M.A.6    Shin, W.S.7    Liao, J.K.8
  • 38
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes, P., M. Suzuki, and D. N. Granger. 1991. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. USA 88:4651.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4651
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 39
    • 0028828569 scopus 로고
    • Aminoguanidine-provoked leukocyte adherence to rat mesenteric venues: Role of constitutive nitric oxide synthase inhibition
    • Lopez-Belmonte, J., and B. J. Whittle. 1995. Aminoguanidine-provoked leukocyte adherence to rat mesenteric venues: role of constitutive nitric oxide synthase inhibition. Br. J. Pharmacol. 116:2710.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 2710
    • Lopez-Belmonte, J.1    Whittle, B.J.2
  • 40
    • 0028145432 scopus 로고
    • The protective role of endogenously synthesized nitric oxide in staphylococcal enterotoxin B-induced shock in mice
    • Florquin, S., Z. Amraoui, C. Dubois, J. Decuyper, and M. Goldman. 1994. The protective role of endogenously synthesized nitric oxide in staphylococcal enterotoxin B-induced shock in mice. J. Exp. Med. 180:1153.
    • (1994) J. Exp. Med. , vol.180 , pp. 1153
    • Florquin, S.1    Amraoui, Z.2    Dubois, C.3    Decuyper, J.4    Goldman, M.5
  • 41
    • 0025258432 scopus 로고
    • Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat
    • Hutcheson, I. R., B. J. Whittle, and N. K. Boughton-Smith. 1990. Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat. Br. J. Pharmacol. 101:815.
    • (1990) Br. J. Pharmacol. , vol.101 , pp. 815
    • Hutcheson, I.R.1    Whittle, B.J.2    Boughton-Smith, N.K.3
  • 43
    • 0028059215 scopus 로고
    • Comparison of cytokine induction by lipopolysaccharide of Bacteroides fragilis with Salmonella typhimurium in mice
    • Jotwani, R., Y. Tanaka, K. Watanabe, K. Tanaka-Bandoh, N. Kato, and K. Ueno. 1994. Comparison of cytokine induction by lipopolysaccharide of Bacteroides fragilis with Salmonella typhimurium in mice. Microbiol. Immunol. 38:763.
    • (1994) Microbiol. Immunol. , vol.38 , pp. 763
    • Jotwani, R.1    Tanaka, Y.2    Watanabe, K.3    Tanaka-Bandoh, K.4    Kato, N.5    Ueno, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.