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Volumn 72, Issue 3, 2009, Pages 194-214

Identification and functional validation of therapeutic targets for malignant melanoma

Author keywords

Antisense; Functional interrogation; Melanoma; Model systems; RNAi; Targets; Therapy

Indexed keywords

2 (2 METHYL 2 PYRROLIDINYL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; BEVACIZUMAB; BMS 663513; CARBOPLATIN; CEDIRANIB; CY 503; DACARBAZINE; DASATINIB; DOXORUBICIN; ELESCLOMOL; EVEROLIMUS; IPILIMUMAB; MELPHALAN; MICRORNA; MONOCLONAL ANTIBODY; OBLIMERSEN; OXALIPLATIN; PACLITAXEL; PEGINTERFERON ALPHA2B; PLX 4032; SORAFENIB; SUNITINIB; TEMOZOLOMIDE; TEMSIROLIMUS; TICILIMUMAB; TIPIFARNIB; TLN 232; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 71549144773     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2009.02.004     Document Type: Review
Times cited : (8)

References (192)
  • 1
    • 38349138856 scopus 로고    scopus 로고
    • Recent discoveries in the genetics of melanoma and their therapeutic implications
    • Marquette A., Bagot M., Bensussan A., and Dumaz N. Recent discoveries in the genetics of melanoma and their therapeutic implications. Arch Immunol Ther Exp (Warsz) 55 (2007) 363-372
    • (2007) Arch Immunol Ther Exp (Warsz) , vol.55 , pp. 363-372
    • Marquette, A.1    Bagot, M.2    Bensussan, A.3    Dumaz, N.4
  • 2
    • 44649148918 scopus 로고    scopus 로고
    • Current clinical overview of cutaneous melanoma
    • Lens M. Current clinical overview of cutaneous melanoma. Br J Nurs 17 (2008) 300-305
    • (2008) Br J Nurs , vol.17 , pp. 300-305
    • Lens, M.1
  • 3
    • 0141992252 scopus 로고    scopus 로고
    • The melanoma epidemic: res ipsa loquitur
    • Beddingfield III F.C. The melanoma epidemic: res ipsa loquitur. Oncologist 8 (2003) 459-465
    • (2003) Oncologist , vol.8 , pp. 459-465
    • Beddingfield III, F.C.1
  • 4
    • 4344656396 scopus 로고    scopus 로고
    • Management of cutaneous melanoma
    • Tsao H., Atkins M.B., and Sober A.J. Management of cutaneous melanoma. N Engl J Med 351 (2004) 998-1012
    • (2004) N Engl J Med , vol.351 , pp. 998-1012
    • Tsao, H.1    Atkins, M.B.2    Sober, A.J.3
  • 5
    • 0035339880 scopus 로고    scopus 로고
    • High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801
    • Kirkwood J.M., Ibrahim J.G., Sosman J.A., et al. High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. J Clin Oncol 19 (2001) 2370-2380
    • (2001) J Clin Oncol , vol.19 , pp. 2370-2380
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sosman, J.A.3
  • 6
    • 0030030347 scopus 로고    scopus 로고
    • Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684
    • Kirkwood J.M., Strawderman M.H., Ernstoff M.S., Smith T.J., Borden E.C., and Blum R.H. Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684. J Clin Oncol 14 (1996) 7-17
    • (1996) J Clin Oncol , vol.14 , pp. 7-17
    • Kirkwood, J.M.1    Strawderman, M.H.2    Ernstoff, M.S.3    Smith, T.J.4    Borden, E.C.5    Blum, R.H.6
  • 8
    • 0021737072 scopus 로고
    • Selection of metastatic variants on the basis of clonal morphology in vitro
    • Clark S.R., and Sidebottom E. Selection of metastatic variants on the basis of clonal morphology in vitro. Invasion Metastasis 4, Suppl. 1 (1984) 1-11
    • (1984) Invasion Metastasis , vol.4 SUPPL. 1 , pp. 1-11
    • Clark, S.R.1    Sidebottom, E.2
  • 9
    • 0032533594 scopus 로고    scopus 로고
    • Malignant melanoma: modern black plague and genetic black box
    • Chin L., Merlino G., and DePinho R.A. Malignant melanoma: modern black plague and genetic black box. Genes Dev 12 (1998) 3467-3481
    • (1998) Genes Dev , vol.12 , pp. 3467-3481
    • Chin, L.1    Merlino, G.2    DePinho, R.A.3
  • 11
    • 0037271078 scopus 로고    scopus 로고
    • Tumour banks: well-guarded treasures in the interest of patients
    • Oosterhuis J.W., Coebergh J.W., and van Veen E.B. Tumour banks: well-guarded treasures in the interest of patients. Nat Rev Cancer 3 (2003) 73-77
    • (2003) Nat Rev Cancer , vol.3 , pp. 73-77
    • Oosterhuis, J.W.1    Coebergh, J.W.2    van Veen, E.B.3
  • 12
    • 7644232196 scopus 로고    scopus 로고
    • The social and ethical issues of post-genomic human biobanks
    • Cambon-Thomsen A. The social and ethical issues of post-genomic human biobanks. Nat Rev Genet 5 (2004) 866-873
    • (2004) Nat Rev Genet , vol.5 , pp. 866-873
    • Cambon-Thomsen, A.1
  • 13
    • 28844446161 scopus 로고    scopus 로고
    • Current challenges of human tumour banking
    • Morente M.M., and Alonso S. Current challenges of human tumour banking. Hematol Oncol 23 (2005) 54-56
    • (2005) Hematol Oncol , vol.23 , pp. 54-56
    • Morente, M.M.1    Alonso, S.2
  • 14
    • 36849009670 scopus 로고    scopus 로고
    • Experimental anti-tumor therapy in 3-D: spheroids--old hat or new challenge?
    • Friedrich J., Ebner R., and Kunz-Schughart L.A. Experimental anti-tumor therapy in 3-D: spheroids--old hat or new challenge?. Int J Radiat Biol 83 (2007) 849-871
    • (2007) Int J Radiat Biol , vol.83 , pp. 849-871
    • Friedrich, J.1    Ebner, R.2    Kunz-Schughart, L.A.3
  • 15
    • 34447258682 scopus 로고    scopus 로고
    • Microenvironmental influences in melanoma progression
    • Lee J.T., and Herlyn M. Microenvironmental influences in melanoma progression. J Cell Biochem 101 (2007) 862-872
    • (2007) J Cell Biochem , vol.101 , pp. 862-872
    • Lee, J.T.1    Herlyn, M.2
  • 16
    • 33645295820 scopus 로고    scopus 로고
    • Modelling cancer in human skin tissue
    • Khavari P.A. Modelling cancer in human skin tissue. Nat Rev Cancer 6 (2006) 270-280
    • (2006) Nat Rev Cancer , vol.6 , pp. 270-280
    • Khavari, P.A.1
  • 17
    • 35248850211 scopus 로고    scopus 로고
    • Cutaneous melanoma in genetically modified animals
    • Larue L., and Beermann F. Cutaneous melanoma in genetically modified animals. Pigment Cell Res 20 (2007) 485-497
    • (2007) Pigment Cell Res , vol.20 , pp. 485-497
    • Larue, L.1    Beermann, F.2
  • 18
    • 0029148164 scopus 로고
    • Cytogenetics of 158 patients with regional or disseminated melanoma. Subset analysis of near-diploid and simple karyotypes
    • Thompson F.H., Emerson J., Olson S., et al. Cytogenetics of 158 patients with regional or disseminated melanoma. Subset analysis of near-diploid and simple karyotypes. Cancer Genet Cytogenet 83 (1995) 93-104
    • (1995) Cancer Genet Cytogenet , vol.83 , pp. 93-104
    • Thompson, F.H.1    Emerson, J.2    Olson, S.3
  • 19
    • 0030447607 scopus 로고    scopus 로고
    • Clinical implications of cytogenetic abnormalities in melanoma
    • Nelson M.A., Thompson F.H., Emerson J., et al. Clinical implications of cytogenetic abnormalities in melanoma. Surg Clin North Am 76 (1996) 1257-1271
    • (1996) Surg Clin North Am , vol.76 , pp. 1257-1271
    • Nelson, M.A.1    Thompson, F.H.2    Emerson, J.3
  • 20
    • 40549095349 scopus 로고    scopus 로고
    • Unlocking pathology archives for microRNA-profiling
    • Hoefig K.P., Thorns C., Roehle A., et al. Unlocking pathology archives for microRNA-profiling. Anticancer Res 28 (2008) 119-123
    • (2008) Anticancer Res , vol.28 , pp. 119-123
    • Hoefig, K.P.1    Thorns, C.2    Roehle, A.3
  • 21
    • 34447506198 scopus 로고    scopus 로고
    • Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells
    • Li J., Smyth P., Flavin R., et al. Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells. BMC Biotechnol 7 (2007) 36
    • (2007) BMC Biotechnol , vol.7 , pp. 36
    • Li, J.1    Smyth, P.2    Flavin, R.3
  • 22
    • 37349059288 scopus 로고    scopus 로고
    • In situ detection of precursor and mature microRNAs in paraffin embedded, formalin fixed tissues and cell preparations
    • Nuovo G.J. In situ detection of precursor and mature microRNAs in paraffin embedded, formalin fixed tissues and cell preparations. Methods 44 (2008) 39-46
    • (2008) Methods , vol.44 , pp. 39-46
    • Nuovo, G.J.1
  • 23
    • 43749118324 scopus 로고    scopus 로고
    • Accurate molecular characterization of formalin-fixed, paraffin-embedded tissues by microRNA expression profiling
    • Szafranska A.E., Davison T.S., Shingara J., et al. Accurate molecular characterization of formalin-fixed, paraffin-embedded tissues by microRNA expression profiling. J Mol Diagn 10 (2008) 411-414
    • (2008) J Mol Diagn , vol.10 , pp. 411-414
    • Szafranska, A.E.1    Davison, T.S.2    Shingara, J.3
  • 24
    • 33645739022 scopus 로고    scopus 로고
    • Gene expression profiling of primary cutaneous melanoma and clinical outcome
    • Winnepenninckx V., Lazar V., Michiels S., et al. Gene expression profiling of primary cutaneous melanoma and clinical outcome. J Natl Cancer Inst 98 (2006) 472-482
    • (2006) J Natl Cancer Inst , vol.98 , pp. 472-482
    • Winnepenninckx, V.1    Lazar, V.2    Michiels, S.3
  • 25
    • 38849166096 scopus 로고    scopus 로고
    • Modeling genomic diversity and tumor dependency in malignant melanoma
    • Lin W.M., Baker A.C., Beroukhim R., et al. Modeling genomic diversity and tumor dependency in malignant melanoma. Cancer Res 68 (2008) 664-673
    • (2008) Cancer Res , vol.68 , pp. 664-673
    • Lin, W.M.1    Baker, A.C.2    Beroukhim, R.3
  • 26
    • 35248864084 scopus 로고    scopus 로고
    • Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression
    • Ryu B., Kim D.S., Deluca A.M., and Alani R.M. Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression. PLoS ONE 2 (2007) e594
    • (2007) PLoS ONE , vol.2
    • Ryu, B.1    Kim, D.S.2    Deluca, A.M.3    Alani, R.M.4
  • 27
    • 35248899866 scopus 로고    scopus 로고
    • DNA microarray analyses of melanoma gene expression: a decade in the mines
    • Hoek K.S. DNA microarray analyses of melanoma gene expression: a decade in the mines. Pigment Cell Res 20 (2007) 466-484
    • (2007) Pigment Cell Res , vol.20 , pp. 466-484
    • Hoek, K.S.1
  • 28
    • 0001278782 scopus 로고    scopus 로고
    • The Wistar melanoma (WM) cell lines
    • Springer, Netherlands p. 259-74
    • Hsu M.Y. The Wistar melanoma (WM) cell lines. Human cell culture (2002), Springer, Netherlands p. 259-74
    • (2002) Human cell culture
    • Hsu, M.Y.1
  • 29
    • 0028899991 scopus 로고
    • Characterization of selected strongly and weakly invasive sublines of a primary human melanoma cell line and isolation of subtractive cDNA clones
    • Jacob K., Bosserhoff A.K., Wach F., et al. Characterization of selected strongly and weakly invasive sublines of a primary human melanoma cell line and isolation of subtractive cDNA clones. Int J Cancer 60 (1995) 668-675
    • (1995) Int J Cancer , vol.60 , pp. 668-675
    • Jacob, K.1    Bosserhoff, A.K.2    Wach, F.3
  • 30
    • 0018828414 scopus 로고
    • In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties
    • Poste G., Doll J., Hart I.R., and Fidler I.J. In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties. Cancer Res 40 (1980) 1636-1644
    • (1980) Cancer Res , vol.40 , pp. 1636-1644
    • Poste, G.1    Doll, J.2    Hart, I.R.3    Fidler, I.J.4
  • 31
    • 0000629930 scopus 로고
    • Selection of successive tumour lines for metastasis
    • Fidler I.J. Selection of successive tumour lines for metastasis. Nat New Biol 242 (1973) 148-149
    • (1973) Nat New Biol , vol.242 , pp. 148-149
    • Fidler, I.J.1
  • 32
    • 0018864610 scopus 로고
    • The pathogenesis of cancer metastasis
    • Poste G., and Fidler I.J. The pathogenesis of cancer metastasis. Nature 283 (1980) 139-146
    • (1980) Nature , vol.283 , pp. 139-146
    • Poste, G.1    Fidler, I.J.2
  • 33
    • 39149095648 scopus 로고    scopus 로고
    • Relevance of cell culture models in cutaneous tumour biology: Part I: Tumour cell lines
    • Hatina J., and Ruzicka T. Relevance of cell culture models in cutaneous tumour biology: Part I: Tumour cell lines. Hautarzt 59 (2008) 36-45
    • (2008) Hautarzt , vol.59 , pp. 36-45
    • Hatina, J.1    Ruzicka, T.2
  • 34
    • 0034050902 scopus 로고    scopus 로고
    • Systematic variation in gene expression patterns in human cancer cell lines
    • Ross D.T., Scherf U., Eisen M.B., et al. Systematic variation in gene expression patterns in human cancer cell lines. Nat Genet 24 (2000) 227-235
    • (2000) Nat Genet , vol.24 , pp. 227-235
    • Ross, D.T.1    Scherf, U.2    Eisen, M.B.3
  • 35
    • 0027329046 scopus 로고
    • Undifferentiated keratinocytes control growth, morphology, and antigen expression of normal melanocytes through cell-cell contact
    • Valyi-Nagy I.T., Hirka G., Jensen P.J., Shih I.M., Juhasz I., and Herlyn M. Undifferentiated keratinocytes control growth, morphology, and antigen expression of normal melanocytes through cell-cell contact. Lab Invest 69 (1993) 152-159
    • (1993) Lab Invest , vol.69 , pp. 152-159
    • Valyi-Nagy, I.T.1    Hirka, G.2    Jensen, P.J.3    Shih, I.M.4    Juhasz, I.5    Herlyn, M.6
  • 36
    • 0028081689 scopus 로고
    • Regulation of Mel-CAM/MUC18 expression on melanocytes of different stages of tumor progression by normal keratinocytes
    • Shih I.M., Elder D.E., Hsu M.Y., and Herlyn M. Regulation of Mel-CAM/MUC18 expression on melanocytes of different stages of tumor progression by normal keratinocytes. Am J Pathol 145 (1994) 837-845
    • (1994) Am J Pathol , vol.145 , pp. 837-845
    • Shih, I.M.1    Elder, D.E.2    Hsu, M.Y.3    Herlyn, M.4
  • 37
    • 33751213366 scopus 로고    scopus 로고
    • CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1
    • Fukunaga-Kalabis M., Martinez G., Liu Z.J., et al. CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1. J Cell Biol 175 (2006) 563-569
    • (2006) J Cell Biol , vol.175 , pp. 563-569
    • Fukunaga-Kalabis, M.1    Martinez, G.2    Liu, Z.J.3
  • 38
    • 42249083746 scopus 로고    scopus 로고
    • Downregulation of CCN3 expression as a potential mechanism for melanoma progression
    • Fukunaga-Kalabis M., Martinez G., Telson S.M., et al. Downregulation of CCN3 expression as a potential mechanism for melanoma progression. Oncogene 27 (2008) 2552-2560
    • (2008) Oncogene , vol.27 , pp. 2552-2560
    • Fukunaga-Kalabis, M.1    Martinez, G.2    Telson, S.M.3
  • 39
    • 0031770035 scopus 로고    scopus 로고
    • Adenoviral gene transfer of beta3 integrin subunit induces conversion from radial to vertical growth phase in primary human melanoma
    • Hsu M.Y., Shih D.T., Meier F.E., et al. Adenoviral gene transfer of beta3 integrin subunit induces conversion from radial to vertical growth phase in primary human melanoma. Am J Pathol 153 (1998) 1435-1442
    • (1998) Am J Pathol , vol.153 , pp. 1435-1442
    • Hsu, M.Y.1    Shih, D.T.2    Meier, F.E.3
  • 40
    • 0033883797 scopus 로고    scopus 로고
    • Human melanoma progression in skin reconstructs: biological significance of bFGF
    • Meier F., Nesbit M., Hsu M.Y., et al. Human melanoma progression in skin reconstructs: biological significance of bFGF. Am J Pathol 156 (2000) 193-200
    • (2000) Am J Pathol , vol.156 , pp. 193-200
    • Meier, F.1    Nesbit, M.2    Hsu, M.Y.3
  • 41
    • 49249116849 scopus 로고    scopus 로고
    • Transforming growth factor-beta activation promotes genetic context-dependent invasion of immortalized melanocytes
    • Lo R.S., and Witte O.N. Transforming growth factor-beta activation promotes genetic context-dependent invasion of immortalized melanocytes. Cancer Res 68 (2008) 4248-4257
    • (2008) Cancer Res , vol.68 , pp. 4248-4257
    • Lo, R.S.1    Witte, O.N.2
  • 42
    • 21644487903 scopus 로고    scopus 로고
    • Three-dimensional culture of melanoma cells profoundly affects gene expression profile: a high density oligonucleotide array study
    • Ghosh S., Spagnoli G.C., Martin I., et al. Three-dimensional culture of melanoma cells profoundly affects gene expression profile: a high density oligonucleotide array study. J Cell Physiol 204 (2005) 522-531
    • (2005) J Cell Physiol , vol.204 , pp. 522-531
    • Ghosh, S.1    Spagnoli, G.C.2    Martin, I.3
  • 43
    • 34548410347 scopus 로고    scopus 로고
    • Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: a role for T-cadherin in tumor angiogenesis
    • Ghosh S., Joshi M.B., Ivanov D., et al. Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: a role for T-cadherin in tumor angiogenesis. FEBS Lett 581 (2007) 4523-4528
    • (2007) FEBS Lett , vol.581 , pp. 4523-4528
    • Ghosh, S.1    Joshi, M.B.2    Ivanov, D.3
  • 44
    • 33745075558 scopus 로고    scopus 로고
    • Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases
    • Smalley K.S., Haass N.K., Brafford P.A., Lioni M., Flaherty K.T., and Herlyn M. Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases. Mol Cancer Ther 5 (2006) 1136-1144
    • (2006) Mol Cancer Ther , vol.5 , pp. 1136-1144
    • Smalley, K.S.1    Haass, N.K.2    Brafford, P.A.3    Lioni, M.4    Flaherty, K.T.5    Herlyn, M.6
  • 45
    • 48649085443 scopus 로고    scopus 로고
    • Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression
    • Smalley K.S., Contractor R., Nguyen T.K., et al. Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression. Cancer Res 68 (2008) 5743-5752
    • (2008) Cancer Res , vol.68 , pp. 5743-5752
    • Smalley, K.S.1    Contractor, R.2    Nguyen, T.K.3
  • 46
    • 24944554507 scopus 로고    scopus 로고
    • Selective evolutionary pressure from the tissue microenvironment drives tumor progression
    • Smalley K.S., Brafford P.A., and Herlyn M. Selective evolutionary pressure from the tissue microenvironment drives tumor progression. Semin Cancer Biol 15 (2005) 451-459
    • (2005) Semin Cancer Biol , vol.15 , pp. 451-459
    • Smalley, K.S.1    Brafford, P.A.2    Herlyn, M.3
  • 47
    • 27544498809 scopus 로고    scopus 로고
    • Induction of hepatocyte growth factor/scatter factor by fibroblast clustering directly promotes tumor cell invasiveness
    • Kankuri E., Cholujova D., Comajova M., Vaheri A., and Bizik J. Induction of hepatocyte growth factor/scatter factor by fibroblast clustering directly promotes tumor cell invasiveness. Cancer Res 65 (2005) 9914-9922
    • (2005) Cancer Res , vol.65 , pp. 9914-9922
    • Kankuri, E.1    Cholujova, D.2    Comajova, M.3    Vaheri, A.4    Bizik, J.5
  • 48
    • 35348880889 scopus 로고    scopus 로고
    • SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth
    • Prada F., Benedetti L.G., Bravo A.I., Alvarez M.J., Carbone C., and Podhajcer O.L. SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth. J Invest Dermatol 127 (2007) 2618-2628
    • (2007) J Invest Dermatol , vol.127 , pp. 2618-2628
    • Prada, F.1    Benedetti, L.G.2    Bravo, A.I.3    Alvarez, M.J.4    Carbone, C.5    Podhajcer, O.L.6
  • 49
    • 41549135210 scopus 로고    scopus 로고
    • Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models
    • Kloss D., Kurz R., Jahnke H.G., et al. Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models. Biosens Bioelectron 23 (2008) 1473-1480
    • (2008) Biosens Bioelectron , vol.23 , pp. 1473-1480
    • Kloss, D.1    Kurz, R.2    Jahnke, H.G.3
  • 50
    • 33947265488 scopus 로고    scopus 로고
    • Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis
    • Javelaud D., Mohammad K.S., McKenna C.R., et al. Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis. Cancer Res 67 (2007) 2317-2324
    • (2007) Cancer Res , vol.67 , pp. 2317-2324
    • Javelaud, D.1    Mohammad, K.S.2    McKenna, C.R.3
  • 51
    • 0024262906 scopus 로고
    • A murine model of experimental metastasis to bone and bone marrow
    • Arguello F., Baggs R.B., and Frantz C.N. A murine model of experimental metastasis to bone and bone marrow. Cancer Res 48 (1988) 6876-6881
    • (1988) Cancer Res , vol.48 , pp. 6876-6881
    • Arguello, F.1    Baggs, R.B.2    Frantz, C.N.3
  • 53
    • 34047218964 scopus 로고    scopus 로고
    • Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, small-animal CT, and bioluminescence imaging
    • Deroose C.M., De A., Loening A.M., et al. Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, small-animal CT, and bioluminescence imaging. J Nucl Med 48 (2007) 295-303
    • (2007) J Nucl Med , vol.48 , pp. 295-303
    • Deroose, C.M.1    De, A.2    Loening, A.M.3
  • 54
    • 34248169598 scopus 로고    scopus 로고
    • Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects
    • Ray P., Tsien R., and Gambhir S.S. Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects. Cancer Res 67 (2007) 3085-3093
    • (2007) Cancer Res , vol.67 , pp. 3085-3093
    • Ray, P.1    Tsien, R.2    Gambhir, S.S.3
  • 56
    • 0027739271 scopus 로고
    • Growth and invasion of human melanomas in human skin grafted to immunodeficient mice
    • Juhasz I., Albelda S.M., Elder D.E., et al. Growth and invasion of human melanomas in human skin grafted to immunodeficient mice. Am J Pathol 143 (1993) 528-537
    • (1993) Am J Pathol , vol.143 , pp. 528-537
    • Juhasz, I.1    Albelda, S.M.2    Elder, D.E.3
  • 57
    • 18644382594 scopus 로고    scopus 로고
    • CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis
    • Lazarov M., Kubo Y., Cai T., et al. CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis. Nat Med 8 (2002) 1105-1114
    • (2002) Nat Med , vol.8 , pp. 1105-1114
    • Lazarov, M.1    Kubo, Y.2    Cai, T.3
  • 58
    • 0037421484 scopus 로고    scopus 로고
    • NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
    • Dajee M., Lazarov M., Zhang J.Y., et al. NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature 421 (2003) 639-643
    • (2003) Nature , vol.421 , pp. 639-643
    • Dajee, M.1    Lazarov, M.2    Zhang, J.Y.3
  • 59
    • 22844445932 scopus 로고    scopus 로고
    • Use of human tissue to assess the oncogenic activity of melanoma-associated mutations
    • Chudnovsky Y., Adams A.E., Robbins P.B., Lin Q., and Khavari P.A. Use of human tissue to assess the oncogenic activity of melanoma-associated mutations. Nat Genet 37 (2005) 745-749
    • (2005) Nat Genet , vol.37 , pp. 745-749
    • Chudnovsky, Y.1    Adams, A.E.2    Robbins, P.B.3    Lin, Q.4    Khavari, P.A.5
  • 61
    • 48649110016 scopus 로고    scopus 로고
    • Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis
    • Inoue-Narita T., Hamada K., Sasaki T., et al. Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis. Cancer Res 68 (2008) 5760-5768
    • (2008) Cancer Res , vol.68 , pp. 5760-5768
    • Inoue-Narita, T.1    Hamada, K.2    Sasaki, T.3
  • 62
    • 48649088341 scopus 로고    scopus 로고
    • Catch of the day: zebrafish as a human cancer model
    • Stoletov K., and Klemke R. Catch of the day: zebrafish as a human cancer model. Oncogene 27 (2008) 4509-4520
    • (2008) Oncogene , vol.27 , pp. 4509-4520
    • Stoletov, K.1    Klemke, R.2
  • 63
    • 13444258032 scopus 로고    scopus 로고
    • BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma
    • Patton E.E., Widlund H.R., Kutok J.L., et al. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Curr Biol 15 (2005) 249-254
    • (2005) Curr Biol , vol.15 , pp. 249-254
    • Patton, E.E.1    Widlund, H.R.2    Kutok, J.L.3
  • 64
    • 38649140712 scopus 로고    scopus 로고
    • Transparent adult zebrafish as a tool for in vivo transplantation analysis
    • White R.M., Sessa A., Burke C., et al. Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell 2 (2008) 183-189
    • (2008) Cell Stem Cell , vol.2 , pp. 183-189
    • White, R.M.1    Sessa, A.2    Burke, C.3
  • 66
    • 33645095718 scopus 로고    scopus 로고
    • Distinguishing melanocytic nevi from melanoma by DNA copy number changes: comparative genomic hybridization as a research and diagnostic tool
    • Bauer J., and Bastian B.C. Distinguishing melanocytic nevi from melanoma by DNA copy number changes: comparative genomic hybridization as a research and diagnostic tool. Dermatol Ther 19 (2006) 40-49
    • (2006) Dermatol Ther , vol.19 , pp. 40-49
    • Bauer, J.1    Bastian, B.C.2
  • 67
    • 10744230160 scopus 로고    scopus 로고
    • High-resolution analysis of DNA copy number using oligonucleotide microarrays
    • Bignell G.R., Huang J., Greshock J., et al. High-resolution analysis of DNA copy number using oligonucleotide microarrays. Genome Res 14 (2004) 287-295
    • (2004) Genome Res , vol.14 , pp. 287-295
    • Bignell, G.R.1    Huang, J.2    Greshock, J.3
  • 68
    • 0142219891 scopus 로고    scopus 로고
    • Functional proteomic analysis of melanoma progression
    • Bernard K., Litman E., Fitzpatrick J.L., et al. Functional proteomic analysis of melanoma progression. Cancer Res 63 (2003) 6716-6725
    • (2003) Cancer Res , vol.63 , pp. 6716-6725
    • Bernard, K.1    Litman, E.2    Fitzpatrick, J.L.3
  • 69
    • 33645048160 scopus 로고    scopus 로고
    • Proteomic and SAGE profiling of murine melanoma progression indicates the reduction of proteins responsible for ROS degradation
    • de Souza G.A., Godoy L.M., Teixeira V.R., et al. Proteomic and SAGE profiling of murine melanoma progression indicates the reduction of proteins responsible for ROS degradation. Proteomics 6 (2006) 1460-1470
    • (2006) Proteomics , vol.6 , pp. 1460-1470
    • de Souza, G.A.1    Godoy, L.M.2    Teixeira, V.R.3
  • 70
    • 23744447337 scopus 로고    scopus 로고
    • Analysis of candidate genes through a proteomics-based approach in primary cell lines from malignant melanomas and their metastases
    • Carta F., Demuro P.P., Zanini C., et al. Analysis of candidate genes through a proteomics-based approach in primary cell lines from malignant melanomas and their metastases. Melanoma Res 15 (2005) 235-244
    • (2005) Melanoma Res , vol.15 , pp. 235-244
    • Carta, F.1    Demuro, P.P.2    Zanini, C.3
  • 71
    • 55249105481 scopus 로고    scopus 로고
    • Comparative proteomic analysis of matched primary and metastatic melanoma cell lines
    • Al-Ghoul M., Bruck T.B., Lauer-Fields J.L., et al. Comparative proteomic analysis of matched primary and metastatic melanoma cell lines. J Proteome Res 7 (2008) 4107-4118
    • (2008) J Proteome Res , vol.7 , pp. 4107-4118
    • Al-Ghoul, M.1    Bruck, T.B.2    Lauer-Fields, J.L.3
  • 72
    • 38149096186 scopus 로고    scopus 로고
    • Bim expression is reduced in human cutaneous melanomas
    • Dai D.L., Wang Y., Liu M., Martinka M., and Li G. Bim expression is reduced in human cutaneous melanomas. J Invest Dermatol 128 (2008) 403-407
    • (2008) J Invest Dermatol , vol.128 , pp. 403-407
    • Dai, D.L.1    Wang, Y.2    Liu, M.3    Martinka, M.4    Li, G.5
  • 73
    • 0034812398 scopus 로고    scopus 로고
    • Tissue microarray (TMA) technology: miniaturized pathology archives for high-throughput in situ studies
    • Bubendorf L., Nocito A., Moch H., and Sauter G. Tissue microarray (TMA) technology: miniaturized pathology archives for high-throughput in situ studies. J Pathol 195 (2001) 72-79
    • (2001) J Pathol , vol.195 , pp. 72-79
    • Bubendorf, L.1    Nocito, A.2    Moch, H.3    Sauter, G.4
  • 74
    • 49349105425 scopus 로고    scopus 로고
    • Role of ING4 in human melanoma cell migration, invasion and patient survival
    • Li J., Martinka M., and Li G. Role of ING4 in human melanoma cell migration, invasion and patient survival. Carcinogenesis 29 (2008) 1373-1379
    • (2008) Carcinogenesis , vol.29 , pp. 1373-1379
    • Li, J.1    Martinka, M.2    Li, G.3
  • 75
    • 49249129411 scopus 로고    scopus 로고
    • Novel role for RGS1 in melanoma progression
    • Rangel J., Nosrati M., Leong S.P., et al. Novel role for RGS1 in melanoma progression. Am J Surg Pathol 32 (2008) 1207-1212
    • (2008) Am J Surg Pathol , vol.32 , pp. 1207-1212
    • Rangel, J.1    Nosrati, M.2    Leong, S.P.3
  • 76
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for high-throughput molecular profiling of tumor specimens
    • Kononen J., Bubendorf L., Kallioniemi A., et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 4 (1998) 844-847
    • (1998) Nat Med , vol.4 , pp. 844-847
    • Kononen, J.1    Bubendorf, L.2    Kallioniemi, A.3
  • 77
    • 43049133807 scopus 로고    scopus 로고
    • MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth
    • Schultz J., Lorenz P., Gross G., Ibrahim S., and Kunz M. MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. Cell Res 18 (2008) 549-557
    • (2008) Cell Res , vol.18 , pp. 549-557
    • Schultz, J.1    Lorenz, P.2    Gross, G.3    Ibrahim, S.4    Kunz, M.5
  • 78
    • 56149110341 scopus 로고    scopus 로고
    • Integrin beta(3) expression is regulated by let-7a miRNA in malignant melanoma
    • Muller D.W., and Bosserhoff A.K. Integrin beta(3) expression is regulated by let-7a miRNA in malignant melanoma. Oncogene 27 (2008) 6698-6706
    • (2008) Oncogene , vol.27 , pp. 6698-6706
    • Muller, D.W.1    Bosserhoff, A.K.2
  • 79
    • 42349087828 scopus 로고    scopus 로고
    • The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms
    • Felicetti F., Errico M.C., Bottero L., et al. The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms. Cancer Res 68 (2008) 2745-2754
    • (2008) Cancer Res , vol.68 , pp. 2745-2754
    • Felicetti, F.1    Errico, M.C.2    Bottero, L.3
  • 80
    • 8744239629 scopus 로고    scopus 로고
    • DNA microarrays: from structural genomics to functional genomics. The applications of gene chips in dermatology and dermatopathology
    • [quiz 93-6]
    • Sellheyer K., and Belbin T.J. DNA microarrays: from structural genomics to functional genomics. The applications of gene chips in dermatology and dermatopathology. J Am Acad Dermatol 51 (2004) 681-692 [quiz 93-6]
    • (2004) J Am Acad Dermatol , vol.51 , pp. 681-692
    • Sellheyer, K.1    Belbin, T.J.2
  • 81
    • 29244448340 scopus 로고    scopus 로고
    • Microarray data analysis: from disarray to consolidation and consensus
    • Allison D.B., Cui X., Page G.P., and Sabripour M. Microarray data analysis: from disarray to consolidation and consensus. Nat Rev Genet 7 (2006) 55-65
    • (2006) Nat Rev Genet , vol.7 , pp. 55-65
    • Allison, D.B.1    Cui, X.2    Page, G.P.3    Sabripour, M.4
  • 83
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • Clark E.A., Golub T.R., Lander E.S., and Hynes R.O. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406 (2000) 532-535
    • (2000) Nature , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 84
    • 0029852580 scopus 로고    scopus 로고
    • Use of a cDNA microarray to analyse gene expression patterns in human cancer
    • DeRisi J., Penland L., Brown P.O., et al. Use of a cDNA microarray to analyse gene expression patterns in human cancer. Nat Genet 14 (1996) 457-460
    • (1996) Nat Genet , vol.14 , pp. 457-460
    • DeRisi, J.1    Penland, L.2    Brown, P.O.3
  • 85
    • 27744548525 scopus 로고    scopus 로고
    • Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies
    • Gallagher W.M., Bergin O.E., Rafferty M., et al. Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies. Carcinogenesis 26 (2005) 1856-1867
    • (2005) Carcinogenesis , vol.26 , pp. 1856-1867
    • Gallagher, W.M.1    Bergin, O.E.2    Rafferty, M.3
  • 87
    • 0142084471 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in models of melanoma progression by cDNA array analysis: SPARC, MIF and a novel cathepsin protease characterize aggressive phenotypes
    • Rumpler G., Becker B., Hafner C., et al. Identification of differentially expressed genes in models of melanoma progression by cDNA array analysis: SPARC, MIF and a novel cathepsin protease characterize aggressive phenotypes. Exp Dermatol 12 (2003) 761-771
    • (2003) Exp Dermatol , vol.12 , pp. 761-771
    • Rumpler, G.1    Becker, B.2    Hafner, C.3
  • 88
    • 0033932797 scopus 로고    scopus 로고
    • Identification of tumor-suppressor genes using human melanoma cell lines UACC903, UACC903(+6), and SRS3 by comparison of expression profiles
    • Su Y.A., Bittner M.L., Chen Y., et al. Identification of tumor-suppressor genes using human melanoma cell lines UACC903, UACC903(+6), and SRS3 by comparison of expression profiles. Mol Carcinog 28 (2000) 119-127
    • (2000) Mol Carcinog , vol.28 , pp. 119-127
    • Su, Y.A.1    Bittner, M.L.2    Chen, Y.3
  • 89
    • 0034601455 scopus 로고    scopus 로고
    • Molecular classification of cutaneous malignant melanoma by gene expression profiling
    • Bittner M., Meltzer P., Chen Y., et al. Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature 406 (2000) 536-540
    • (2000) Nature , vol.406 , pp. 536-540
    • Bittner, M.1    Meltzer, P.2    Chen, Y.3
  • 90
    • 20944437231 scopus 로고    scopus 로고
    • The gene expression signatures of melanoma progression
    • Haqq C., Nosrati M., Sudilovsky D., et al. The gene expression signatures of melanoma progression. Proc Natl Acad Sci U S A 102 (2005) 6092-6097
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 6092-6097
    • Haqq, C.1    Nosrati, M.2    Sudilovsky, D.3
  • 91
    • 27744600102 scopus 로고    scopus 로고
    • Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas
    • Smith A.P., Hoek K., and Becker D. Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas. Cancer Biol Ther 4 (2005) 1018-1029
    • (2005) Cancer Biol Ther , vol.4 , pp. 1018-1029
    • Smith, A.P.1    Hoek, K.2    Becker, D.3
  • 92
    • 33847397814 scopus 로고    scopus 로고
    • Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues
    • Jaeger J., Koczan D., Thiesen H.J., et al. Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues. Clin Cancer Res 13 (2007) 806-815
    • (2007) Clin Cancer Res , vol.13 , pp. 806-815
    • Jaeger, J.1    Koczan, D.2    Thiesen, H.J.3
  • 93
    • 49649103221 scopus 로고    scopus 로고
    • The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis
    • Riker A.I., Enkemann S.A., Fodstad O., et al. The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis. BMC Med Genomics 1 (2008) 13
    • (2008) BMC Med Genomics , vol.1 , pp. 13
    • Riker, A.I.1    Enkemann, S.A.2    Fodstad, O.3
  • 94
    • 34248223535 scopus 로고    scopus 로고
    • A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis
    • Alonso S.R., Tracey L., Ortiz P., et al. A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis. Cancer Res 67 (2007) 3450-3460
    • (2007) Cancer Res , vol.67 , pp. 3450-3460
    • Alonso, S.R.1    Tracey, L.2    Ortiz, P.3
  • 95
    • 52649132297 scopus 로고    scopus 로고
    • Predicting clinical outcome through molecular profiling in stage III melanoma
    • John T., Black M.A., Toro T.T., et al. Predicting clinical outcome through molecular profiling in stage III melanoma. Clin Cancer Res 14 (2008) 5173-5180
    • (2008) Clin Cancer Res , vol.14 , pp. 5173-5180
    • John, T.1    Black, M.A.2    Toro, T.T.3
  • 96
    • 37648998629 scopus 로고    scopus 로고
    • Getting to the root of miRNA-mediated gene silencing
    • Eulalio A., Huntzinger E., and Izaurralde E. Getting to the root of miRNA-mediated gene silencing. Cell 132 (2008) 9-14
    • (2008) Cell , vol.132 , pp. 9-14
    • Eulalio, A.1    Huntzinger, E.2    Izaurralde, E.3
  • 98
    • 37549024511 scopus 로고    scopus 로고
    • MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
    • Blenkiron C., Goldstein L.D., Thorne N.P., et al. MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol 8 (2007) R214
    • (2007) Genome Biol , vol.8
    • Blenkiron, C.1    Goldstein, L.D.2    Thorne, N.P.3
  • 99
    • 51049123624 scopus 로고    scopus 로고
    • Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer
    • Ambs S., Prueitt R.L., Yi M., et al. Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer. Cancer Res 68 (2008) 6162-6170
    • (2008) Cancer Res , vol.68 , pp. 6162-6170
    • Ambs, S.1    Prueitt, R.L.2    Yi, M.3
  • 100
    • 0142151099 scopus 로고    scopus 로고
    • Classifying melanocytic tumors based on DNA copy number changes
    • Bastian B.C., Olshen A.B., LeBoit P.E., and Pinkel D. Classifying melanocytic tumors based on DNA copy number changes. Am J Pathol 163 (2003) 1765-1770
    • (2003) Am J Pathol , vol.163 , pp. 1765-1770
    • Bastian, B.C.1    Olshen, A.B.2    LeBoit, P.E.3    Pinkel, D.4
  • 101
    • 33745168962 scopus 로고    scopus 로고
    • microRNAs exhibit high frequency genomic alterations in human cancer
    • Zhang L., Huang J., Yang N., et al. microRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci U S A 103 (2006) 9136-9141
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 9136-9141
    • Zhang, L.1    Huang, J.2    Yang, N.3
  • 102
    • 27844567142 scopus 로고    scopus 로고
    • Distinct sets of genetic alterations in melanoma
    • Curtin J.A., Fridlyand J., Kageshita T., et al. Distinct sets of genetic alterations in melanoma. N Engl J Med 353 (2005) 2135-2147
    • (2005) N Engl J Med , vol.353 , pp. 2135-2147
    • Curtin, J.A.1    Fridlyand, J.2    Kageshita, T.3
  • 103
    • 21844478747 scopus 로고    scopus 로고
    • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
    • Garraway L.A., Widlund H.R., Rubin M.A., et al. Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature 436 (2005) 117-122
    • (2005) Nature , vol.436 , pp. 117-122
    • Garraway, L.A.1    Widlund, H.R.2    Rubin, M.A.3
  • 104
    • 33847293670 scopus 로고    scopus 로고
    • High-throughput oncogene mutation profiling in human cancer
    • Thomas R.K., Baker A.C., Debiasi R.M., et al. High-throughput oncogene mutation profiling in human cancer. Nat Genet 39 (2007) 347-351
    • (2007) Nat Genet , vol.39 , pp. 347-351
    • Thomas, R.K.1    Baker, A.C.2    Debiasi, R.M.3
  • 105
    • 0038456399 scopus 로고    scopus 로고
    • PTEN signaling pathways in melanoma
    • Wu H., Goel V., and Haluska F.G. PTEN signaling pathways in melanoma. Oncogene 22 (2003) 3113-3122
    • (2003) Oncogene , vol.22 , pp. 3113-3122
    • Wu, H.1    Goel, V.2    Haluska, F.G.3
  • 106
    • 55249096894 scopus 로고    scopus 로고
    • Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast
    • de Godoy L.M., Olsen J.V., Cox J., et al. Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast. Nature 455 (2008) 1251-1254
    • (2008) Nature , vol.455 , pp. 1251-1254
    • de Godoy, L.M.1    Olsen, J.V.2    Cox, J.3
  • 107
    • 33744990201 scopus 로고    scopus 로고
    • Proteomic analysis of tumor establishment and growth in the B16-F10 mouse melanoma model
    • Culp W.D., Neal R., Massey R., Egevad L., Pisa P., and Garland D. Proteomic analysis of tumor establishment and growth in the B16-F10 mouse melanoma model. J Proteome Res 5 (2006) 1332-1343
    • (2006) J Proteome Res , vol.5 , pp. 1332-1343
    • Culp, W.D.1    Neal, R.2    Massey, R.3    Egevad, L.4    Pisa, P.5    Garland, D.6
  • 108
    • 33645400195 scopus 로고    scopus 로고
    • Proteomic analysis of uveal melanoma reveals novel potential markers involved in tumor progression
    • Zuidervaart W., Hensbergen P.J., Wong M.C., et al. Proteomic analysis of uveal melanoma reveals novel potential markers involved in tumor progression. Invest Ophthalmol Vis Sci 47 (2006) 786-793
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 786-793
    • Zuidervaart, W.1    Hensbergen, P.J.2    Wong, M.C.3
  • 109
    • 35648989121 scopus 로고    scopus 로고
    • Proteomics-based strategy to delineate the molecular mechanisms of the metastasis suppressor gene BRMS1
    • Rivera J., Megias D., and Bravo J. Proteomics-based strategy to delineate the molecular mechanisms of the metastasis suppressor gene BRMS1. J Proteome Res 6 (2007) 4006-4018
    • (2007) J Proteome Res , vol.6 , pp. 4006-4018
    • Rivera, J.1    Megias, D.2    Bravo, J.3
  • 110
    • 33751011581 scopus 로고    scopus 로고
    • Proteomic analysis of plasma membrane from hypoxia-adapted malignant melanoma
    • Stockwin L.H., Blonder J., Bumke M.A., et al. Proteomic analysis of plasma membrane from hypoxia-adapted malignant melanoma. J Proteome Res 5 (2006) 2996-3007
    • (2006) J Proteome Res , vol.5 , pp. 2996-3007
    • Stockwin, L.H.1    Blonder, J.2    Bumke, M.A.3
  • 111
    • 10644250717 scopus 로고    scopus 로고
    • Identification of proteins regulated by interferon-alpha in resistant and sensitive malignant melanoma cell lines
    • Craven R.A., Stanley A.J., Hanrahan S., et al. Identification of proteins regulated by interferon-alpha in resistant and sensitive malignant melanoma cell lines. Proteomics 4 (2004) 3998-4009
    • (2004) Proteomics , vol.4 , pp. 3998-4009
    • Craven, R.A.1    Stanley, A.J.2    Hanrahan, S.3
  • 112
    • 34547217974 scopus 로고    scopus 로고
    • Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum
    • Pardo M., Garcia A., Antrobus R., Blanco M.J., Dwek R.A., and Zitzmann N. Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum. J Proteome Res 6 (2007) 2802-2811
    • (2007) J Proteome Res , vol.6 , pp. 2802-2811
    • Pardo, M.1    Garcia, A.2    Antrobus, R.3    Blanco, M.J.4    Dwek, R.A.5    Zitzmann, N.6
  • 113
    • 52049093719 scopus 로고    scopus 로고
    • Quantitative analysis of surface plasma membrane proteins of primary and metastatic melanoma cells
    • Qiu H., and Wang Y. Quantitative analysis of surface plasma membrane proteins of primary and metastatic melanoma cells. J Proteome Res 7 (2008) 1904-1915
    • (2008) J Proteome Res , vol.7 , pp. 1904-1915
    • Qiu, H.1    Wang, Y.2
  • 114
    • 55849147637 scopus 로고    scopus 로고
    • Proteomic analysis of membrane rafts of melanoma cells identifies protein patterns characteristic of the tumor progression stage
    • Baruthio F., Quadroni M., Ruegg C., and Mariotti A. Proteomic analysis of membrane rafts of melanoma cells identifies protein patterns characteristic of the tumor progression stage. Proteomics 8 (2008) 4733-4747
    • (2008) Proteomics , vol.8 , pp. 4733-4747
    • Baruthio, F.1    Quadroni, M.2    Ruegg, C.3    Mariotti, A.4
  • 115
    • 53149130583 scopus 로고    scopus 로고
    • Proteomics. Will biomarkers take off at last?
    • Service R.F. Proteomics. Will biomarkers take off at last?. Science 321 (2008) 1760
    • (2008) Science , vol.321 , pp. 1760
    • Service, R.F.1
  • 116
    • 1842559788 scopus 로고    scopus 로고
    • Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments
    • Baggerly K.A., Morris J.S., and Coombes K.R. Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments. Bioinformatics 20 (2004) 777-785
    • (2004) Bioinformatics , vol.20 , pp. 777-785
    • Baggerly, K.A.1    Morris, J.S.2    Coombes, K.R.3
  • 117
    • 24644434436 scopus 로고    scopus 로고
    • Serum proteomic fingerprinting discriminates between clinical stages and predicts disease progression in melanoma patients
    • Mian S., Ugurel S., Parkinson E., et al. Serum proteomic fingerprinting discriminates between clinical stages and predicts disease progression in melanoma patients. J Clin Oncol 23 (2005) 5088-5093
    • (2005) J Clin Oncol , vol.23 , pp. 5088-5093
    • Mian, S.1    Ugurel, S.2    Parkinson, E.3
  • 118
    • 45749091807 scopus 로고    scopus 로고
    • Direct tissue proteomics in human diseases: potential applications to melanoma research
    • Rezaul K., Wilson L.L., and Han D.K. Direct tissue proteomics in human diseases: potential applications to melanoma research. Expert Rev Proteomics 5 (2008) 405-412
    • (2008) Expert Rev Proteomics , vol.5 , pp. 405-412
    • Rezaul, K.1    Wilson, L.L.2    Han, D.K.3
  • 119
    • 41649100689 scopus 로고    scopus 로고
    • Mining the plasma proteome for cancer biomarkers
    • Hanash S.M., Pitteri S.J., and Faca V.M. Mining the plasma proteome for cancer biomarkers. Nature 452 (2008) 571-579
    • (2008) Nature , vol.452 , pp. 571-579
    • Hanash, S.M.1    Pitteri, S.J.2    Faca, V.M.3
  • 120
    • 20444480567 scopus 로고    scopus 로고
    • Technology insight: identification of biomarkers with tissue microarray technology
    • Giltnane J.M., and Rimm D.L. Technology insight: identification of biomarkers with tissue microarray technology. Nat Clin Pract Oncol 1 (2004) 104-111
    • (2004) Nat Clin Pract Oncol , vol.1 , pp. 104-111
    • Giltnane, J.M.1    Rimm, D.L.2
  • 121
    • 0035061867 scopus 로고    scopus 로고
    • Tissue microarray technology for high-throughput molecular profiling of cancer
    • Kallioniemi O.P., Wagner U., Kononen J., and Sauter G. Tissue microarray technology for high-throughput molecular profiling of cancer. Hum Mol Genet 10 (2001) 657-662
    • (2001) Hum Mol Genet , vol.10 , pp. 657-662
    • Kallioniemi, O.P.1    Wagner, U.2    Kononen, J.3    Sauter, G.4
  • 122
    • 1542574206 scopus 로고    scopus 로고
    • Progression in cutaneous malignant melanoma is associated with distinct expression profiles: a tissue microarray-based study
    • Alonso S.R., Ortiz P., Pollan M., et al. Progression in cutaneous malignant melanoma is associated with distinct expression profiles: a tissue microarray-based study. Am J Pathol 164 (2004) 193-203
    • (2004) Am J Pathol , vol.164 , pp. 193-203
    • Alonso, S.R.1    Ortiz, P.2    Pollan, M.3
  • 123
    • 0346365379 scopus 로고    scopus 로고
    • Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival
    • Berger A.J., Kluger H.M., Li N., et al. Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival. Cancer Res 63 (2003) 8103-8107
    • (2003) Cancer Res , vol.63 , pp. 8103-8107
    • Berger, A.J.1    Kluger, H.M.2    Li, N.3
  • 124
    • 1642375902 scopus 로고    scopus 로고
    • Validation of tissue microarray for the immunohistochemical profiling of melanoma
    • Pacifico M.D., Grover R., Richman P., Daley F., and Wilson G.D. Validation of tissue microarray for the immunohistochemical profiling of melanoma. Melanoma Res 14 (2004) 39-42
    • (2004) Melanoma Res , vol.14 , pp. 39-42
    • Pacifico, M.D.1    Grover, R.2    Richman, P.3    Daley, F.4    Wilson, G.D.5
  • 125
    • 9244241036 scopus 로고    scopus 로고
    • Automated quantitative analysis of HDM2 expression in malignant melanoma shows association with early-stage disease and improved outcome
    • Berger A.J., Camp R.L., Divito K.A., Kluger H.M., Halaban R., and Rimm D.L. Automated quantitative analysis of HDM2 expression in malignant melanoma shows association with early-stage disease and improved outcome. Cancer Res 64 (2004) 8767-8772
    • (2004) Cancer Res , vol.64 , pp. 8767-8772
    • Berger, A.J.1    Camp, R.L.2    Divito, K.A.3    Kluger, H.M.4    Halaban, R.5    Rimm, D.L.6
  • 126
    • 9244229046 scopus 로고    scopus 로고
    • Automated quantitative analysis of tissue microarrays reveals an association between high Bcl-2 expression and improved outcome in melanoma
    • Divito K.A., Berger A.J., Camp R.L., Dolled-Filhart M., Rimm D.L., and Kluger H.M. Automated quantitative analysis of tissue microarrays reveals an association between high Bcl-2 expression and improved outcome in melanoma. Cancer Res 64 (2004) 8773-8777
    • (2004) Cancer Res , vol.64 , pp. 8773-8777
    • Divito, K.A.1    Berger, A.J.2    Camp, R.L.3    Dolled-Filhart, M.4    Rimm, D.L.5    Kluger, H.M.6
  • 127
    • 40149102363 scopus 로고    scopus 로고
    • HSP90 as a marker of progression in melanoma
    • McCarthy M.M., Pick E., Kluger Y., et al. HSP90 as a marker of progression in melanoma. Ann Oncol 19 (2008) 590-594
    • (2008) Ann Oncol , vol.19 , pp. 590-594
    • McCarthy, M.M.1    Pick, E.2    Kluger, Y.3
  • 128
    • 45549089565 scopus 로고    scopus 로고
    • The art and design of genetic screens: RNA interference
    • Boutros M., and Ahringer J. The art and design of genetic screens: RNA interference. Nat Rev Genet 9 (2008) 554-566
    • (2008) Nat Rev Genet , vol.9 , pp. 554-566
    • Boutros, M.1    Ahringer, J.2
  • 130
    • 33845780974 scopus 로고    scopus 로고
    • RNA learns from antisense
    • Corey D.R. RNA learns from antisense. Nat Chem Biol 3 (2007) 8-11
    • (2007) Nat Chem Biol , vol.3 , pp. 8-11
    • Corey, D.R.1
  • 131
    • 20344371233 scopus 로고    scopus 로고
    • Antisense therapy for cancer
    • Gleave M.E., and Monia B.P. Antisense therapy for cancer. Nat Rev Cancer 5 (2005) 468-479
    • (2005) Nat Rev Cancer , vol.5 , pp. 468-479
    • Gleave, M.E.1    Monia, B.P.2
  • 132
    • 33750600634 scopus 로고    scopus 로고
    • Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group
    • Bedikian A.Y., Millward M., Pehamberger H., et al. Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group. J Clin Oncol 24 (2006) 4738-4745
    • (2006) J Clin Oncol , vol.24 , pp. 4738-4745
    • Bedikian, A.Y.1    Millward, M.2    Pehamberger, H.3
  • 133
    • 33845755467 scopus 로고    scopus 로고
    • Illuminating the silence: understanding the structure and function of small RNAs
    • Rana T.M. Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol 8 (2007) 23-36
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 23-36
    • Rana, T.M.1
  • 134
    • 42549096043 scopus 로고    scopus 로고
    • Expression strategies for short hairpin RNA interference triggers
    • Rossi J.J. Expression strategies for short hairpin RNA interference triggers. Hum Gene Ther 19 (2008) 313-317
    • (2008) Hum Gene Ther , vol.19 , pp. 313-317
    • Rossi, J.J.1
  • 135
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon G.J., and Rossi J.J. Unlocking the potential of the human genome with RNA interference. Nature 431 (2004) 371-378
    • (2004) Nature , vol.431 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 136
    • 33748209616 scopus 로고    scopus 로고
    • Efficient prediction of siRNAs with siRNArules 1.0: an open-source JAVA approach to siRNA algorithms
    • Holen T. Efficient prediction of siRNAs with siRNArules 1.0: an open-source JAVA approach to siRNA algorithms. RNA 12 (2006) 1620-1625
    • (2006) RNA , vol.12 , pp. 1620-1625
    • Holen, T.1
  • 137
    • 33746772726 scopus 로고    scopus 로고
    • Demonstration of two novel methods for predicting functional siRNA efficiency
    • Jia P., Shi T., Cai Y., and Li Y. Demonstration of two novel methods for predicting functional siRNA efficiency. BMC Bioinform 7 (2006) 271
    • (2006) BMC Bioinform , vol.7 , pp. 271
    • Jia, P.1    Shi, T.2    Cai, Y.3    Li, Y.4
  • 138
    • 33846634136 scopus 로고    scopus 로고
    • Selecting effective siRNAs based on guide RNA structure
    • Koberle C., Kaufmann S.H., and Patzel V. Selecting effective siRNAs based on guide RNA structure. Nat Protoc 1 (2006) 1832-1839
    • (2006) Nat Protoc , vol.1 , pp. 1832-1839
    • Koberle, C.1    Kaufmann, S.H.2    Patzel, V.3
  • 140
    • 47249138782 scopus 로고    scopus 로고
    • Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides
    • Juliano R., Alam M.R., Dixit V., and Kang H. Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides. Nucleic Acids Res 36 (2008) 4158-4171
    • (2008) Nucleic Acids Res , vol.36 , pp. 4158-4171
    • Juliano, R.1    Alam, M.R.2    Dixit, V.3    Kang, H.4
  • 141
    • 42549142820 scopus 로고    scopus 로고
    • Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA
    • Li S.D., Chono S., and Huang L. Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA. Mol Ther 16 (2008) 942-946
    • (2008) Mol Ther , vol.16 , pp. 942-946
    • Li, S.D.1    Chono, S.2    Huang, L.3
  • 142
    • 36849044732 scopus 로고    scopus 로고
    • Nonviral delivery of synthetic siRNAs in vivo
    • Akhtar S., and Benter I.F. Nonviral delivery of synthetic siRNAs in vivo. J Clin Invest 117 (2007) 3623-3632
    • (2007) J Clin Invest , vol.117 , pp. 3623-3632
    • Akhtar, S.1    Benter, I.F.2
  • 143
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • Kim D.H., and Rossi J.J. Strategies for silencing human disease using RNA interference. Nat Rev Genet 8 (2007) 173-184
    • (2007) Nat Rev Genet , vol.8 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 144
    • 34248656980 scopus 로고    scopus 로고
    • Gene manipulation through the use of small interfering RNA (siRNA): from in vitro to in vivo applications
    • Kumar L.D., and Clarke A.R. Gene manipulation through the use of small interfering RNA (siRNA): from in vitro to in vivo applications. Adv Drug Deliv Rev 59 (2007) 87-100
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 87-100
    • Kumar, L.D.1    Clarke, A.R.2
  • 145
    • 1442274582 scopus 로고    scopus 로고
    • High-efficiency stable gene transduction in primary human melanocytes using a lentiviral expression system
    • Dunlap S., Yu X., Cheng L., Civin C.I., and Alani R.M. High-efficiency stable gene transduction in primary human melanocytes using a lentiviral expression system. J Invest Dermatol 122 (2004) 549-551
    • (2004) J Invest Dermatol , vol.122 , pp. 549-551
    • Dunlap, S.1    Yu, X.2    Cheng, L.3    Civin, C.I.4    Alani, R.M.5
  • 146
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs-microRNAs with a role in cancer
    • Esquela-Kerscher A., and Slack F.J. Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 6 (2006) 259-269
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 147
    • 43649087713 scopus 로고    scopus 로고
    • Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling
    • Worley L.A., Long M.D., Onken M.D., and Harbour J.W. Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling. Melanoma Res 18 (2008) 184-190
    • (2008) Melanoma Res , vol.18 , pp. 184-190
    • Worley, L.A.1    Long, M.D.2    Onken, M.D.3    Harbour, J.W.4
  • 148
    • 33645135862 scopus 로고    scopus 로고
    • Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?
    • Weiler J., Hunziker J., and Hall J. Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?. Gene Ther 13 (2006) 496-502
    • (2006) Gene Ther , vol.13 , pp. 496-502
    • Weiler, J.1    Hunziker, J.2    Hall, J.3
  • 149
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • Krutzfeldt J., Rajewsky N., Braich R., et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 438 (2005) 685-689
    • (2005) Nature , vol.438 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 150
    • 33747855481 scopus 로고    scopus 로고
    • Comparing antibody and small-molecule therapies for cancer
    • Imai K., and Takaoka A. Comparing antibody and small-molecule therapies for cancer. Nat Rev Cancer 6 (2006) 714-727
    • (2006) Nat Rev Cancer , vol.6 , pp. 714-727
    • Imai, K.1    Takaoka, A.2
  • 151
    • 34548066554 scopus 로고    scopus 로고
    • CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling
    • Evelyn C.R., Wade S.M., Wang Q., et al. CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling. Mol Cancer Ther 6 (2007) 2249-2260
    • (2007) Mol Cancer Ther , vol.6 , pp. 2249-2260
    • Evelyn, C.R.1    Wade, S.M.2    Wang, Q.3
  • 152
    • 51049094438 scopus 로고    scopus 로고
    • A small-molecule E2F inhibitor blocks growth in a melanoma culture model
    • Ma Y., Kurtyka C.A., Boyapalle S., et al. A small-molecule E2F inhibitor blocks growth in a melanoma culture model. Cancer Res 68 (2008) 6292-6299
    • (2008) Cancer Res , vol.68 , pp. 6292-6299
    • Ma, Y.1    Kurtyka, C.A.2    Boyapalle, S.3
  • 153
    • 1642503079 scopus 로고    scopus 로고
    • High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity
    • Rowlands M.G., Newbatt Y.M., Prodromou C., Pearl L.H., Workman P., and Aherne W. High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity. Anal Biochem 327 (2004) 176-183
    • (2004) Anal Biochem , vol.327 , pp. 176-183
    • Rowlands, M.G.1    Newbatt, Y.M.2    Prodromou, C.3    Pearl, L.H.4    Workman, P.5    Aherne, W.6
  • 154
    • 33749546461 scopus 로고    scopus 로고
    • Identification of novel small-molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding
    • Jones D.T., and Harris A.L. Identification of novel small-molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding. Mol Cancer Ther 5 (2006) 2193-2202
    • (2006) Mol Cancer Ther , vol.5 , pp. 2193-2202
    • Jones, D.T.1    Harris, A.L.2
  • 155
    • 4344623889 scopus 로고    scopus 로고
    • Imatinib as a paradigm of targeted therapies
    • Druker B.J. Imatinib as a paradigm of targeted therapies. Adv Cancer Res 91 (2004) 1-30
    • (2004) Adv Cancer Res , vol.91 , pp. 1-30
    • Druker, B.J.1
  • 156
    • 50249141632 scopus 로고    scopus 로고
    • Phase II trial of imatinib mesylate in patients with metastatic melanoma
    • Kim K.B., Eton O., Davis D.W., et al. Phase II trial of imatinib mesylate in patients with metastatic melanoma. Br J Cancer 99 (2008) 734-740
    • (2008) Br J Cancer , vol.99 , pp. 734-740
    • Kim, K.B.1    Eton, O.2    Davis, D.W.3
  • 157
    • 40749124035 scopus 로고    scopus 로고
    • The Mitogen-activated protein/extracellular signal-regulated kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel
    • Haass N.K., Sproesser K., Nguyen T.K., et al. The Mitogen-activated protein/extracellular signal-regulated kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel. Clin Cancer Res 14 (2008) 230-239
    • (2008) Clin Cancer Res , vol.14 , pp. 230-239
    • Haass, N.K.1    Sproesser, K.2    Nguyen, T.K.3
  • 158
    • 33947210121 scopus 로고    scopus 로고
    • In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors
    • Sharp S.Y., Boxall K., Rowlands M., et al. In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors. Cancer Res 67 (2007) 2206-2216
    • (2007) Cancer Res , vol.67 , pp. 2206-2216
    • Sharp, S.Y.1    Boxall, K.2    Rowlands, M.3
  • 159
    • 34247465448 scopus 로고    scopus 로고
    • c-Met is a potentially new therapeutic target for treatment of human melanoma
    • Puri N., Ahmed S., Janamanchi V., et al. c-Met is a potentially new therapeutic target for treatment of human melanoma. Clin Cancer Res 13 (2007) 2246-2253
    • (2007) Clin Cancer Res , vol.13 , pp. 2246-2253
    • Puri, N.1    Ahmed, S.2    Janamanchi, V.3
  • 160
    • 47249145702 scopus 로고    scopus 로고
    • JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis
    • Alexaki V.I., Javelaud D., and Mauviel A. JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis. Pigment Cell Melanoma Res 21 (2008) 429-438
    • (2008) Pigment Cell Melanoma Res , vol.21 , pp. 429-438
    • Alexaki, V.I.1    Javelaud, D.2    Mauviel, A.3
  • 161
  • 163
    • 49649118218 scopus 로고    scopus 로고
    • Drosophila melanogaster and the development of biology in the 20th century
    • Arias A.M. Drosophila melanogaster and the development of biology in the 20th century. Methods Mol Biol 420 (2008) 1-25
    • (2008) Methods Mol Biol , vol.420 , pp. 1-25
    • Arias, A.M.1
  • 164
    • 1642488119 scopus 로고    scopus 로고
    • Functional genomic approaches using the nematode Caenorhabditis elegans as a model system
    • Lee J., Nam S., Hwang S.B., et al. Functional genomic approaches using the nematode Caenorhabditis elegans as a model system. J Biochem Mol Biol 37 (2004) 107-113
    • (2004) J Biochem Mol Biol , vol.37 , pp. 107-113
    • Lee, J.1    Nam, S.2    Hwang, S.B.3
  • 165
    • 31744445957 scopus 로고    scopus 로고
    • Microarrays of lentiviruses for gene function screens in immortalized and primary cells
    • Bailey S.N., Ali S.M., Carpenter A.E., Higgins C.O., and Sabatini D.M. Microarrays of lentiviruses for gene function screens in immortalized and primary cells. Nat Methods 3 (2006) 117-122
    • (2006) Nat Methods , vol.3 , pp. 117-122
    • Bailey, S.N.1    Ali, S.M.2    Carpenter, A.E.3    Higgins, C.O.4    Sabatini, D.M.5
  • 167
    • 41649115887 scopus 로고    scopus 로고
    • Discovery of novel targets with high throughput RNA interference screening
    • Kassner P.D. Discovery of novel targets with high throughput RNA interference screening. Comb Chem High Throughput Screen 11 (2008) 175-184
    • (2008) Comb Chem High Throughput Screen , vol.11 , pp. 175-184
    • Kassner, P.D.1
  • 168
    • 34249847158 scopus 로고    scopus 로고
    • In vivo selection for metastasis promoting genes in the mouse
    • Gumireddy K., Sun F., Klein-Szanto A.J., et al. In vivo selection for metastasis promoting genes in the mouse. Proc Natl Acad Sci U S A 104 (2007) 6696-6701
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 6696-6701
    • Gumireddy, K.1    Sun, F.2    Klein-Szanto, A.J.3
  • 169
    • 34147198467 scopus 로고    scopus 로고
    • Synthetic lethal screen identification of chemosensitizer loci in cancer cells
    • Whitehurst A.W., Bodemann B.O., Cardenas J., et al. Synthetic lethal screen identification of chemosensitizer loci in cancer cells. Nature 446 (2007) 815-819
    • (2007) Nature , vol.446 , pp. 815-819
    • Whitehurst, A.W.1    Bodemann, B.O.2    Cardenas, J.3
  • 171
    • 35348858911 scopus 로고    scopus 로고
    • Cell-based high-content screening of small-molecule libraries
    • Korn K., and Krausz E. Cell-based high-content screening of small-molecule libraries. Curr Opin Chem Biol 11 (2007) 503-510
    • (2007) Curr Opin Chem Biol , vol.11 , pp. 503-510
    • Korn, K.1    Krausz, E.2
  • 172
    • 33646033137 scopus 로고    scopus 로고
    • A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
    • Moffat J., Grueneberg D.A., Yang X., et al. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 124 (2006) 1283-1298
    • (2006) Cell , vol.124 , pp. 1283-1298
    • Moffat, J.1    Grueneberg, D.A.2    Yang, X.3
  • 173
    • 0034007555 scopus 로고    scopus 로고
    • Duration of survival for disseminated malignant melanoma: results of a meta-analysis
    • Lee M.L., Tomsu K., and Von Eschen K.B. Duration of survival for disseminated malignant melanoma: results of a meta-analysis. Melanoma Res 10 (2000) 81-92
    • (2000) Melanoma Res , vol.10 , pp. 81-92
    • Lee, M.L.1    Tomsu, K.2    Von Eschen, K.B.3
  • 174
    • 22744447065 scopus 로고    scopus 로고
    • Novel agents in development for the treatment of melanoma
    • Tarhini A.A., and Agarwala S.S. Novel agents in development for the treatment of melanoma. Expert Opin Invest Drugs 14 (2005) 885-892
    • (2005) Expert Opin Invest Drugs , vol.14 , pp. 885-892
    • Tarhini, A.A.1    Agarwala, S.S.2
  • 175
    • 0028894034 scopus 로고
    • bcl-2 protein expression in cutaneous malignant melanoma and benign melanocytic nevi
    • Cerroni L., Soyer H.P., and Kerl H. bcl-2 protein expression in cutaneous malignant melanoma and benign melanocytic nevi. Am J Dermatopathol 17 (1995) 7-11
    • (1995) Am J Dermatopathol , vol.17 , pp. 7-11
    • Cerroni, L.1    Soyer, H.P.2    Kerl, H.3
  • 177
    • 0031907428 scopus 로고    scopus 로고
    • bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
    • Jansen B., Schlagbauer-Wadl H., Brown B.D., et al. bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat Med 4 (1998) 232-234
    • (1998) Nat Med , vol.4 , pp. 232-234
    • Jansen, B.1    Schlagbauer-Wadl, H.2    Brown, B.D.3
  • 178
    • 0034684471 scopus 로고    scopus 로고
    • Chemosensitisation of malignant melanoma by BCL2 antisense therapy
    • Jansen B., Wacheck V., Heere-Ress E., et al. Chemosensitisation of malignant melanoma by BCL2 antisense therapy. Lancet 356 (2000) 1728-1733
    • (2000) Lancet , vol.356 , pp. 1728-1733
    • Jansen, B.1    Wacheck, V.2    Heere-Ress, E.3
  • 179
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    • Wilhelm S.M., Carter C., Tang L., et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 64 (2004) 7099-7109
    • (2004) Cancer Res , vol.64 , pp. 7099-7109
    • Wilhelm, S.M.1    Carter, C.2    Tang, L.3
  • 180
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies H., Bignell G.R., Cox C., et al. Mutations of the BRAF gene in human cancer. Nature 417 (2002) 949-954
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1    Bignell, G.R.2    Cox, C.3
  • 181
    • 4344584872 scopus 로고    scopus 로고
    • B-RAF is a therapeutic target in melanoma
    • Karasarides M., Chiloeches A., Hayward R., et al. B-RAF is a therapeutic target in melanoma. Oncogene 23 (2004) 6292-6298
    • (2004) Oncogene , vol.23 , pp. 6292-6298
    • Karasarides, M.1    Chiloeches, A.2    Hayward, R.3
  • 182
  • 183
    • 51049098909 scopus 로고    scopus 로고
    • Selected combination therapy with sorafenib: a review of clinical data and perspectives in advanced solid tumors
    • Dal Lago L., D'Hondt V., and Awada A. Selected combination therapy with sorafenib: a review of clinical data and perspectives in advanced solid tumors. Oncologist 13 (2008) 845-858
    • (2008) Oncologist , vol.13 , pp. 845-858
    • Dal Lago, L.1    D'Hondt, V.2    Awada, A.3
  • 184
    • 36849035139 scopus 로고    scopus 로고
    • Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies
    • O'Day S.J., Hamid O., and Urba W.J. Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies. Cancer 110 (2007) 2614-2627
    • (2007) Cancer , vol.110 , pp. 2614-2627
    • O'Day, S.J.1    Hamid, O.2    Urba, W.J.3
  • 185
    • 0028791059 scopus 로고
    • Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
    • Waterhouse P., Penninger J.M., Timms E., et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 270 (1995) 985-988
    • (1995) Science , vol.270 , pp. 985-988
    • Waterhouse, P.1    Penninger, J.M.2    Timms, E.3
  • 186
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol E.A., Borriello F., Schweitzer A.N., Lynch W.P., Bluestone J.A., and Sharpe A.H. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3 (1995) 541-547
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 187
    • 33644659256 scopus 로고    scopus 로고
    • Principles and use of anti-CTLA4 antibody in human cancer immunotherapy
    • Peggs K.S., Quezada S.A., Korman A.J., and Allison J.P. Principles and use of anti-CTLA4 antibody in human cancer immunotherapy. Curr Opin Immunol 18 (2006) 206-213
    • (2006) Curr Opin Immunol , vol.18 , pp. 206-213
    • Peggs, K.S.1    Quezada, S.A.2    Korman, A.J.3    Allison, J.P.4
  • 188
  • 189
    • 55949137090 scopus 로고    scopus 로고
    • Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or decarbazine [DTIC]) in patients with advanced melanoma
    • Abstract LBA9011
    • Ribas A., Hauschild A., Kefford R., et al. Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or decarbazine [DTIC]) in patients with advanced melanoma. J Clin Oncol 26 (2008) Abstract LBA9011
    • (2008) J Clin Oncol , vol.26
    • Ribas, A.1    Hauschild, A.2    Kefford, R.3
  • 190
    • 53349153454 scopus 로고    scopus 로고
    • Elesclomol induces cancer cell apoptosis through oxidative stress
    • Kirshner J.R., He S., Balasubramanyam V., et al. Elesclomol induces cancer cell apoptosis through oxidative stress. Mol Cancer Ther 7 (2008) 2319-2327
    • (2008) Mol Cancer Ther , vol.7 , pp. 2319-2327
    • Kirshner, J.R.1    He, S.2    Balasubramanyam, V.3
  • 191
    • 33846856501 scopus 로고    scopus 로고
    • Phase I clinical trial of STA-4783 in combination with paclitaxel in patients with refractory solid tumors
    • Berkenblit A., Eder Jr. J.P., Ryan D.P., et al. Phase I clinical trial of STA-4783 in combination with paclitaxel in patients with refractory solid tumors. Clin Cancer Res 13 (2007) 584-590
    • (2007) Clin Cancer Res , vol.13 , pp. 584-590
    • Berkenblit, A.1    Eder Jr., J.P.2    Ryan, D.P.3
  • 192
    • 69249142259 scopus 로고    scopus 로고
    • Phase II trial of elesclomol (formerly STA-4783) and paclitaxel in stage IV metastatic melanoma (MM): subgroup analysis by prior chemotherapy
    • Abstract 9036
    • Gonzalez R., Lawson D.H., Weber R.W., et al. Phase II trial of elesclomol (formerly STA-4783) and paclitaxel in stage IV metastatic melanoma (MM): subgroup analysis by prior chemotherapy. J Clin Oncol 26 (2008) Abstract 9036
    • (2008) J Clin Oncol , vol.26
    • Gonzalez, R.1    Lawson, D.H.2    Weber, R.W.3


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