Carcinogenesis in human skin grafted to SCID mice

Cancer Research

Volumn 56, Issue 4, 1996, Pages 757-764

  Soballe, Peter W ^a   Montane, Kathleen T ^b   Satyamoorthy, Kapaettu ^a   Nesbit, Mark ^a   Herlyn, Meenhard ^a  

^a WISTAR INSTITUTE   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN;

ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA DAMAGE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; SKIN GRAFT; TUMOR PROMOTION; ULTRAVIOLET RADIATION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANTIGENS, NEOPLASM; CARCINOGENS; CELL DIFFERENTIATION; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; KERATINS; KI-67 ANTIGEN; MICE; MICE, SCID; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PAPILLOMA; SKIN NEOPLASMS; SKIN TRANSPLANTATION; TETRADECANOYLPHORBOL ACETATE; TRANSPLANTATION, HETEROLOGOUS; ULTRAVIOLET RAYS;

EID: 0030020155     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Yuspa, S H. The pathogenesis of squamous cell cancer lessons learned from studies of skin carcinogenesis. Cancer Res., 54. 1178-1189, 1994.
2. Reifenrath, W. G., Chellquist, E. M., Shipwash, E A., Jederberg, W. W., and Krueger, G. G. Percutaneous penetration in the hairless dog, weanling pig, and grafted athymic nude mouse: evaluation of models for predicting skin penetration in man. Br. J. Dermatol., 111: 123-135, 1984
3. Das, M., Asokan, P., Don, P. S. C. Krueger, G. G., Bickers, D. R., and Mukhtar, H Carcinogen metabolism in human skin grafted onto athymic nude mice: a model system for the study of human skin carcinogenesis Biochem. Biophys. Res Commun., 138: 33-39, 1986.
4. Bohr, V. A., Smith, C. A , Okumoto, D S., and Hanawalt, P. C DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell, 40: 359-369, 1985
5. Husain, Z., Pathak, M. A., Flotte, T., and Wick, M M. Role of ultraviolet radiation in the induction of melanocytic tumors in hairless mice following 7,12-dimethylbenz(a)anthracene application and ultraviolet irradiation. Cancer Res., 51: 4964-4970, 1991.
6. Setlow, R. B. The wavelengths in sunlight effective in producing skin cancer: a theoretical analysis. Proc. Natl. Acad. Sci. USA, 71: 3363-3366, 1974.
7. de Gruijl, F. R., Sterenborg, H. J. C. M., Forbes, P. D., Davies, R. E., Cole, C., Kelfkens, G., van Weelden, H , Slaper, H., and van der Leun, J. C. Wavelength dependence of skin cancer induction by ultraviolet irradiation of albino hairless mice. Cancer Res., 53: 53-60, 1993.
8. Hennings, H., Shores, R. A., Wenk, M. L., Spangler, E. F , Tarone, R , and Yuspa, S. H. Malignant conversion of mouse skin rumors is increased by tumor initiators and unaffected by tumor promoters. Nature (Lond.), 304: 67-69, 1983.
9. Yan, H. C , Juhasz, I., Pilewski, J., Murphy, G. F., Herlyn, M., and Albelda, S M. Human/severe combined immunodeficient mouse chimeras: an experimental in vivo model system to study the regulation of human endothelial cell-leukocyte adhesion molecules J. Clin Invest., 91: 986-996, 1993.
10. Juhasz, I., Albelda, S. M., Elder, D. E., Murphy, G. F., Adachi, K., Herlyn, D., Valyi-Nagy, I. T., and Herlyn, M. Growth and invasion of human melanomas in human skin grafted to immunodeficient mice. Am J Pathol , 143: 528-537, 1993
11. Bosma, M. J , and Carol, A. M. The SCID mouse mutant: definition, characterization, and potential uses. Ann. Rev. Immunol., 9: 323-350, 1991.
12. Cattoretti, G., Becker, M. H. G., Key, G., Duchrow, M., Schluter, C., Galle, J., and Gerdes, J. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol., 168: 357-363, 1992
13. Rodeck, U., Herlyn, M., Herlyn, D. Molthoff, C., Atkinson, B., Varello, M., Steplewski, Z., and Koprowski, H. Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects. Cancer Res., 47: 3692-3696, 1987.
14. Cunha, G R., and Vanderslice, K. D. Identification in histological sections of species origin of cells from mouse, rat and human Stain Technol., 59 7-12, 1984.
15. Batzer, M A , and Deininger, P. L. A human-specific subfamily of Alu sequences. Genomics, 9: 481-487, 1991.
16. Morison, W L , Jerdan, M S , Hoover, T. L., and Farmer, E. R. UV radiation-induced tumors in haired mice: identification as squamous cell carcinomas. J. Natl. Cancer Inst., 77: 1155-1162, 1986
17. Urano, K , Katakai, Y., Tokuda, Y., Ueyama, Y , Nomura, T., and Yamamoto, S. Failure of genotoxic carcinogens to produce tumors in human skin xenografts transplanted to SCID mice. Carcinogenesis (Lond), 16 2223-2226, 1995.
18. Hill, L. L , Perussia, B., McCue, P. A., and Korngold, R. Effect of human natural killer cells on the metastatic growth of human melanoma xenografts in mice with severe combined immunodeficiency Cancer Res., 54: 763-770, 1994.
19. O'Connell, J. F , Klein-Szanto, A J. P., DiGiovanni, D. M., Fries, J. W , and Slaga, T. J Enhanced malignant progression of mouse skin tumors by the free-radical generator benzoyl peroxide. Cancer Res , 46: 2863-2865, 1986.
20. Hennings, H., Shores, R., Wenk, M. L , Spangler, E. F , Tarone, R , and Yuspa, S. H. Enhanced malignant conversion of benign mouse skin tumors by cisplatin J. Natl. Cancer Inst., 82: 836-840, 1990
21. Yuspa, S. H. Cutaneous chemical Carcinogenesis. J. Am. Acad. Dermatol., 15: 1031-1043, 1986.
22. Yohn, J., Lehman, T. A., Kurian, P , Ribovich, M., and Milo, G. E. Benzo[a]pyrene diol epoxide I modification of DNA in human skin xenografts J Invest. Dermatol , 91: 363-368, 1988.
23. MacLeod, M C , Powell, K. L., and Tran, N. Binding of the transcription factor, SpI, to non-target sites in DNA modified by benzo[a]pyrene diol epoxide. Carcinogenesis (Lond.), 16: 975-983, 1995.
24. Findlay, G M. Ultraviolet light and skin cancer. Lancet, 2: 1070-1073, 1928
25. IACR monographs on the evaluation of carcinogenic risks to humans. Solar and Ultraviolet Radiation, Vol. 55, pp. 1-316. Lyon, France WHO, 1992.
26. Glass, A G., and Hoover, R N The emerging epidemic of melanoma and squamous cell skin cancer. J. Am. Med. Assoc., 262: 2097-2100, 1989.
27. Kerr, J B., and McElroy, C. T. Evidence for large upward trends of ultraviolet-B radiation linked to ozone depletion. Science (Washington DC), 262: 1032-1034, 1993
28. Oxholm, A., Oxholm, P., Staberg, B., and Bemdzten, K. Immunohistological detection of interleukin-1 like molecules and tumor necrosis factor in human epidermis before and after UVB irradiation in vivo. Br. J. Dermatol., 118: 369-376, 1988.
29. Black, A. K., Greaves, M. W., Hensby, C. N., and Plummer, N. A. Increased prostaglandins E2 and F2a in human skin at 6 and 24 h after ultraviolet B irradiation (290-320 nm). Br. J Clin. Pharmacol., 5: 431-436, 1978.
30. de Vos, S., Brach, M., Budnik, A., Grewe, M., Herrmann, F., and Krutmann, J. Post-transcriptional regulation of interleukin-6 gene expression in human keratinocytes by ultraviolet B radiation. J. Invest. Dermatol., 103. 92-96, 1994.
31. Imokawa, G., Yada, Y , and Miyagishi, M. Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes. J. Biol. Chem., 267. 24675-24680, 1992
32. Kramer, M., Sachsenmaier, C., Herrlich, P., and Rahmsdorf, H. J. UV irradiation-induced interleukin-1 and basic fibroblast growth factor synthesis and release mediate part of the UV response. J Biol. Chem., 268: 6734-6741, 1992
33. Rosen, C. F., Gajic, D., and Drucker, D. J. Ultraviolet radiation induction of ornithine decarboxylase in rat keratinocytes Cancer Res , 50. 2631-2635, 1990.
34. Warmuth, I., Harth, Y., Matsui, M. S., Wang, N., and DeLeo, V. A. Ultraviolet radiation induces phosphorylation of the epidermal growth factor receptor. Cancer Res., 54: 374-376, 1994.
35. Roddey, P. K., Garmyn, M., Park, H. Y., Bhawan, J., and Gilchrest, B. A. Ultraviolet irradiation induces c-fos but not c-Ha-ras proto-oncogene expression in human epidermis J. Invest. Dermatol., 102: 296-299, 1994.
36. Ronai, Z. A., Okin, E., and Weinstein, I B Ultraviolet light induces the expression of oncogenes in rat fibroblast and human keratinocyte cells. Oncogene, 2: 201-204, 1988.
37. Kripke, M. L., Cox, P. A., Alas, L. G., and Yarosh, D B. Pyrimidine dimers in DNA initiate systemic immunosuppression in UV-irradiated mice. Proc. Natl. Acad. Sci. USA, 89: 7516-7520, 1992.
38. Gilchrest, B. A., Zhai, S., Eller, M S., Yarosh, D. B., and Yaar, M. Treatment of human melanocytes and S91 melanoma cells with the DNA repair enzyme T4 endonuclease V enhances melanogenesis after ultraviolet irradiation. J. Invest. Dermatol., 101: 666-672, 1993.
39. Pearse, A. D., Gaskell, S. A., and Marks, R Epidermal changes in human skin following irradiation with either UVB or UVA. J. Invest. Dermatol., 88: 83-87, 1987
40. Matsui, M. S., and DeLeo, V. A. Longwave ultraviolet radiation and promotion of skin cancer Cancer Cells, 3: 8-12, 1991.
41. Krueger, G. G , and Shelby, J. Biology of human skin transplanted to the nude mouse. I. Response to agents which modify epidermal proliferation. J. Invest. Dermatol., 76: 506-510, 1981.
42. Graem, N. Epidermal changes following application of 7,12-dimethylbenz(a)anthracene and 12-O-tetradecanoylphorbol-13-acetate to human skin transplanted to nude mice studied with histological species markers Cancer Res., 46. 278-284, 1986.
43. Yuspa, S. H., Viguera, C., and Nims, R. Maintenance of human skin on nude mice for studies of chemical carcinogenesis. Cancer Lett., 6: 301-310, 1979.
44. Danska, J. S., Pflumio, F., Williams, C. J , Huner, O , Dick, J. E., and Guidos, C. J Rescue of T cell-specific V(D)J recombination in SCID mice by DNA-damaging agents. Science (Washington DC), 266: 450-454, 1994.
45. Mombaerts, P., Iacomini, J , Johnson, R. S , Herrup, K., Tonegawa, S., and Papaioannou, V E. RAG-1 deficient mice have no mature B and T lymphocytes Cell, 63: 869-877, 1992.
46. Scott, R J., Hall, P. A., Haldane, J. S., Van Noorden, S., Price, Y., Lane, D. P., and Wright, N. A. A comparison of immunohistochemical markers of cell proliferation with experimentally determined growth fraction. J. Pathol , 165: 173-178, 1991.
47. McCormick, D , Chong, H , Hobbs, C , Datta, C , and Hall, P. A. Detection of the Ki-67 antigen in fixed and wax-embedded sections with the monoclonal antibody MIB1. Histopathology, 22: 355-360, 1993
48. Galvin, S , Loomis, C L , Manabe, M., Dhouailly, D., and Sun, T-T. The major pathways of keratinocyte differentiation as defined by keratin expression: an overview. Adv. Dermatol., 4: 277-300, 1989.