메뉴 건너뛰기




Volumn 7, Issue 8, 2008, Pages 2319-2327

Elesclomol induces cancer cell apoptosis through oxidative stress

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; ELESCLOMOL; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 53349153454     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-08-0298     Document Type: Article
Times cited : (234)

References (39)
  • 2
    • 33846856501 scopus 로고    scopus 로고
    • Phase I clinical trial of STA-4783 in combination with paclitaxel in patients with refractory solid tumors
    • Berkenblit A, Eder JP, Jr., Ryan DP, et al. Phase I clinical trial of STA-4783 in combination with paclitaxel in patients with refractory solid tumors. Clin Cancer Res 2007;13:584-90.
    • (2007) Clin Cancer Res , vol.13 , pp. 584-590
    • Berkenblit, A.1    Eder Jr., J.P.2    Ryan, D.P.3
  • 3
    • 39149104690 scopus 로고    scopus 로고
    • Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials
    • Korn EL, Liu PY, Lee SJ, et al. Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials. J Clin Oncol 2008;26:527-34.
    • (2008) J Clin Oncol , vol.26 , pp. 527-534
    • Korn, E.L.1    Liu, P.Y.2    Lee, S.J.3
  • 5
    • 34648813720 scopus 로고    scopus 로고
    • ROS as signaling molecules: Mechanisms that generate specificity in ROS homeostasis
    • D'Autreaux B, Toledano MB. ROS as signaling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol 2007;8:813-24.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 813-824
    • D'Autreaux, B.1    Toledano, M.B.2
  • 6
    • 0026021362 scopus 로고
    • Production of large amounts of hydrogen peroxide by human tumor cells
    • Szatrowski TP, Nathan CF. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 1991;51:794-8.
    • (1991) Cancer Res , vol.51 , pp. 794-798
    • Szatrowski, T.P.1    Nathan, C.F.2
  • 8
    • 0033517275 scopus 로고    scopus 로고
    • Cell transformation by the superoxide-generating oxidase Mox1
    • Suh YA, Arnold RS, Lassegue B, et al. Cell transformation by the superoxide-generating oxidase Mox1. Nature 1999;401:79-82.
    • (1999) Nature , vol.401 , pp. 79-82
    • Suh, Y.A.1    Arnold, R.S.2    Lassegue, B.3
  • 9
    • 0034699513 scopus 로고    scopus 로고
    • Superoxide dismutase as a target for the selective killing of cancer cells
    • Huang P, Feng L, OldhamEA, Keating MJ, Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature 2000;407:390-5.
    • (2000) Nature , vol.407 , pp. 390-395
    • Huang, P.1    Feng, L.2    Oldham, E.A.3    Keating, M.J.4    Plunkett, W.5
  • 10
    • 0141509869 scopus 로고    scopus 로고
    • Inhibition of mitochondrial respiration: A novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism
    • Pelicano H, Feng L, Zhou Y, et al. Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism. J Biol Chem 2003;278:37 832-9.
    • (2003) J Biol Chem , vol.278 , Issue.37 , pp. 832-839
    • Pelicano, H.1    Feng, L.2    Zhou, Y.3
  • 11
    • 33748146888 scopus 로고    scopus 로고
    • Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate
    • TrachoothamD, Zhou Y, Zhang H, et al. Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate. Cancer Cell 2006;10:241-52.
    • (2006) Cancer Cell , vol.10 , pp. 241-252
    • Trachootham, D.1    Zhou, Y.2    Zhang, H.3
  • 12
    • 0037033050 scopus 로고    scopus 로고
    • CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation
    • Hase H, Kanno Y, Kojima H, Morimoto C, Okumura K, Kobata T. CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation. J Biol Chem 2002;277:46950-8.
    • (2002) J Biol Chem , vol.277 , pp. 46950-46958
    • Hase, H.1    Kanno, Y.2    Kojima, H.3    Morimoto, C.4    Okumura, K.5    Kobata, T.6
  • 13
    • 0027135501 scopus 로고
    • The function of heat-shock proteins in stress tolerance: Degradation and reactivation of damaged proteins
    • Parsell DA, Lindquist S. The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins. Annu Rev Genet 1993;27:437-96.
    • (1993) Annu Rev Genet , vol.27 , pp. 437-496
    • Parsell, D.A.1    Lindquist, S.2
  • 14
    • 33749641286 scopus 로고    scopus 로고
    • Metallothionein redox cycle and function
    • Kang YJ. Metallothionein redox cycle and function. Exp Biol Med (Maywood) 2006;231:1459-67.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 1459-1467
    • Kang, Y.J.1
  • 15
    • 29244453628 scopus 로고    scopus 로고
    • Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines
    • Lecane PS, Karaman MW, Sirisawad M, et al. Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines. Cancer Res 2005;65:11676-88.
    • (2005) Cancer Res , vol.65 , pp. 11676-11688
    • Lecane, P.S.1    Karaman, M.W.2    Sirisawad, M.3
  • 16
    • 0032612322 scopus 로고    scopus 로고
    • Stress-induced activation of the heat-shock response: Cell and molecular biology of heat-shock factors
    • Cotto JJ, Morimoto RI. Stress-induced activation of the heat-shock response: cell and molecular biology of heat-shock factors. Biochem Soc Symp 1999;64:105-18.
    • (1999) Biochem Soc Symp , vol.64 , pp. 105-118
    • Cotto, J.J.1    Morimoto, R.I.2
  • 18
    • 33847050801 scopus 로고    scopus 로고
    • Cell survival responses to environmental stresses via the Keap1-2-ARE pathway
    • Kensler TW, Wakabayashi N, Biswal S. Cell survival responses to environmental stresses via the Keap1-2-ARE pathway. Annu Rev Pharmacol Toxicol 2007;47:89-116.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 89-116
    • Kensler, T.W.1    Wakabayashi, N.2    Biswal, S.3
  • 19
    • 0141819958 scopus 로고    scopus 로고
    • The stress response: Implications for the clinical development of hsp90 inhibitors
    • Whitesell L, Bagatell R, Falsey R. The stress response: implications for the clinical development of hsp90 inhibitors. Curr Cancer Drug Targets 2003;3:349-58.
    • (2003) Curr Cancer Drug Targets , vol.3 , pp. 349-358
    • Whitesell, L.1    Bagatell, R.2    Falsey, R.3
  • 20
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. Mitochondria and apoptosis. Science 1998;28:1309-12.
    • (1998) Science , vol.28 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 21
    • 21244437180 scopus 로고    scopus 로고
    • Molecular mechanisms of survival and apoptosis in RAW 264.7 macrophages under oxidative stress
    • Zhang Y, Fong CC, Wong MS, et al. Molecular mechanisms of survival and apoptosis in RAW 264.7 macrophages under oxidative stress. Apoptosis 2005;10:545-56.
    • (2005) Apoptosis , vol.10 , pp. 545-556
    • Zhang, Y.1    Fong, C.C.2    Wong, M.S.3
  • 22
    • 27944442839 scopus 로고    scopus 로고
    • Disulfide relays and phosphorylative cascades: Partners in redox-mediated signaling pathways
    • Filomeni G, Rotilio G, Ciriolo MR. Disulfide relays and phosphorylative cascades: partners in redox-mediated signaling pathways. Cell Death Differ 2005;12:1555-63.
    • (2005) Cell Death Differ , vol.12 , pp. 1555-1563
    • Filomeni, G.1    Rotilio, G.2    Ciriolo, M.R.3
  • 23
    • 24744453917 scopus 로고    scopus 로고
    • Arsenic trioxide induces Hsp70 expression via reactive oxygen species and JNK pathway in MDA231 cells
    • KimYH, Park EJ, Han ST, Park JW, Kwon TK. Arsenic trioxide induces Hsp70 expression via reactive oxygen species and JNK pathway in MDA231 cells. Life Sci 2005;77:2783-93.
    • (2005) Life Sci , vol.77 , pp. 2783-2793
    • Kim, Y.H.1    Park, E.J.2    Han, S.T.3    Park, J.W.4    Kwon, T.K.5
  • 24
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000;408:239-47.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 25
    • 0035200658 scopus 로고    scopus 로고
    • Cellular thiols and reactive oxygen species in drug-induced apoptosis
    • Davis W, Jr., Ronai Z, Tew KD. Cellular thiols and reactive oxygen species in drug-induced apoptosis. J Pharmacol Exp Ther 2001;296:1-6.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 1-6
    • Davis Jr., W.1    Ronai, Z.2    Tew, K.D.3
  • 26
    • 4544229590 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination
    • Li D, Ueta E, Kimura T, Yamamoto T, Osaki T. Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination. Cancer Sci 2004;95:644-50.
    • (2004) Cancer Sci , vol.95 , pp. 644-650
    • Li, D.1    Ueta, E.2    Kimura, T.3    Yamamoto, T.4    Osaki, T.5
  • 27
    • 0033229866 scopus 로고    scopus 로고
    • p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
    • Li PF, Dietz R, von Harsdorf R. p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. EMBO J 1999;18:6027-36.
    • (1999) EMBO J , vol.18 , pp. 6027-6036
    • Li, P.F.1    Dietz, R.2    von Harsdorf, R.3
  • 28
    • 36849034493 scopus 로고    scopus 로고
    • Experimental therapeutics: Targeting the redox Achilles heel of cancer
    • Cabello CM, Bair Iii WB, Wondrak GT. Experimental therapeutics: targeting the redox Achilles heel of cancer. Curr Opin Investig Drugs 2007;8:1022-37.
    • (2007) Curr Opin Investig Drugs , vol.8 , pp. 1022-1037
    • Cabello, C.M.1    Bair Iii, W.B.2    Wondrak, G.T.3
  • 29
    • 33748788835 scopus 로고    scopus 로고
    • Molecular mechanism of "mitocan"-induced apoptosis in cancer cells epitomizes the multiple roles of reactive oxygen species and Bcl-2 family proteins
    • Neuzil J, Wang XF, Dong LF, Low P, Ralph SJ. Molecular mechanism of "mitocan"-induced apoptosis in cancer cells epitomizes the multiple roles of reactive oxygen species and Bcl-2 family proteins. FEBS Lett 2006;580:5125-9.
    • (2006) FEBS Lett , vol.580 , pp. 5125-5129
    • Neuzil, J.1    Wang, X.F.2    Dong, L.F.3    Low, P.4    Ralph, S.J.5
  • 31
    • 24944486664 scopus 로고    scopus 로고
    • Resistance to paclitaxel is proportional to cellular total antioxidant capacity
    • Ramanathan B, Jan KY, Chen CH, Hour TC, Yu HJ, Pu YS. Resistance to paclitaxel is proportional to cellular total antioxidant capacity. Cancer Res 2005;65:8455-60.
    • (2005) Cancer Res , vol.65 , pp. 8455-8460
    • Ramanathan, B.1    Jan, K.Y.2    Chen, C.H.3    Hour, T.C.4    Yu, H.J.5    Pu, Y.S.6
  • 32
    • 33646517942 scopus 로고    scopus 로고
    • Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo
    • Alexandre J, Batteux F, Nicco C, et al. Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo. Int J Cancer 2006;119:41-8.
    • (2006) Int J Cancer , vol.119 , pp. 41-48
    • Alexandre, J.1    Batteux, F.2    Nicco, C.3
  • 34
    • 36048989628 scopus 로고    scopus 로고
    • Reactive oxygen species in melanoma and its therapeutic implications
    • Wittgen HG, van Kempen LC. Reactive oxygen species in melanoma and its therapeutic implications. Melanoma Res 2007;17:400-9.
    • (2007) Melanoma Res , vol.17 , pp. 400-409
    • Wittgen, H.G.1    van Kempen, L.C.2
  • 37
    • 1442360000 scopus 로고    scopus 로고
    • Intrinsic oxidative stress in cancer cells: A biochemical basis for therapeutic selectivity
    • Hileman EO, Liu J, Albitar M, Keating MJ, Huang P. Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity. Cancer Chemother Pharmacol 2004;53:209-19.
    • (2004) Cancer Chemother Pharmacol , vol.53 , pp. 209-219
    • Hileman, E.O.1    Liu, J.2    Albitar, M.3    Keating, M.J.4    Huang, P.5
  • 38
    • 34548386642 scopus 로고    scopus 로고
    • Advanced but not localized prostate cancer is associated with increased oxidative stress
    • Yossepowitch O, Pinchuk I, Gur U, Neumann A, Lichtenberg D, Baniel J. Advanced but not localized prostate cancer is associated with increased oxidative stress. J Urol 2007;178:1238-44.
    • (2007) J Urol , vol.178 , pp. 1238-1244
    • Yossepowitch, O.1    Pinchuk, I.2    Gur, U.3    Neumann, A.4    Lichtenberg, D.5    Baniel, J.6
  • 39
    • 40949159866 scopus 로고    scopus 로고
    • Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype
    • Kumar B, Koul S, Khandrika L, Meacham RB, Koul HK. Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype. Cancer Res 2008;68:1777-85.
    • (2008) Cancer Res , vol.68 , pp. 1777-1785
    • Kumar, B.1    Koul, S.2    Khandrika, L.3    Meacham, R.B.4    Koul, H.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.