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Volumn 5, Issue 4, 2009, Pages 267-276

The biology of persistent infection: Inflammation and demyelination following murine coronavirus infection of the central nervous system

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 12; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; VIRUS RNA;

EID: 70350764833     PISSN: 15733955     EISSN: None     Source Type: Journal    
DOI: 10.2174/157339509789504005     Document Type: Review
Times cited : (19)

References (167)
  • 3
    • 47549090868 scopus 로고    scopus 로고
    • Temporal trends in the incidence of multiple sclerosis: A systematic review
    • Alonso A, Hernan MA. Temporal trends in the incidence of multiple sclerosis: a systematic review. Neurology 2008; 71: 129-135
    • (2008) Neurology , vol.71 , pp. 129-135
    • Alonso, A.1    Hernan, M.A.2
  • 4
    • 0035096330 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis pathogenesis: Implications for diagnosis and therapy
    • Lassmann H, Bruck W, Lucchinetti C. Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy. Trends Mol Med 2001; 7: 115-121
    • (2001) Trends Mol Med , vol.7 , pp. 115-121
    • Lassmann, H.1    Bruck, W.2    Lucchinetti, C.3
  • 5
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
    • Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 2000; 47: 707-717
    • (2000) Ann Neurol , vol.47 , pp. 707-717
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 6
    • 34548133584 scopus 로고    scopus 로고
    • Multiple sclerosis: A complicated picture of autoimmunity
    • McFarland HF, Martin R. Multiple sclerosis: a complicated picture of autoimmunity. Nat Immunol 2007; 8: 913-919
    • (2007) Nat Immunol , vol.8 , pp. 913-919
    • McFarland, H.F.1    Martin, R.2
  • 8
    • 34247590137 scopus 로고    scopus 로고
    • Environmental risk factors for multiple sclerosis. Part I: The role of infection
    • DOI 10.1002/ana.21117
    • Ascherio A, Munger KL. Environmental risk factors for multiple sclerosis. Part I: the role of infection. Ann Neurol 2007; 61: 288-299 (Pubitemid 46676728)
    • (2007) Annals of Neurology , vol.61 , Issue.4 , pp. 288-299
    • Ascherio, A.1    Munger, K.L.2
  • 9
    • 34447508481 scopus 로고    scopus 로고
    • Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors
    • DOI 10.1002/ana.21141
    • Ascherio A, Munger KL. Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors. Ann Neurol 2007; 61: 504-513 (Pubitemid 47068132)
    • (2007) Annals of Neurology , vol.61 , Issue.6 , pp. 504-513
    • Ascherio, A.1    Munger, K.L.2
  • 11
    • 27144538977 scopus 로고    scopus 로고
    • A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis
    • Lincoln MR, Montpetit A, Cader MZ, et al. A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Nat Genet 2005; 37: 1108-1112
    • (2005) Nat Genet , vol.37 , pp. 1108-1112
    • Lincoln, M.R.1    Montpetit, A.2    Cader, M.Z.3
  • 12
    • 0036237054 scopus 로고    scopus 로고
    • Prospective study on the relationship between infections and multiple sclerosis exacerbations
    • Buljevac D, Flach HZ, Hop WC, et al. Prospective study on the relationship between infections and multiple sclerosis exacerbations. Brain 2002; 125: 952-960
    • (2002) Brain , vol.125 , pp. 952-960
    • Buljevac, D.1    Flach, H.Z.2    Hop, W.C.3
  • 13
    • 0028333890 scopus 로고
    • Influence of infection on exacerbations of multiple sclerosis
    • Panitch HS. Influence of infection on exacerbations of multiple sclerosis. Ann Neurol 1994; 36(Suppl): S25-8.
    • (1994) Ann Neurol , vol.36 , Issue.SUPPL.
    • Panitch, H.S.1
  • 14
    • 33644820800 scopus 로고    scopus 로고
    • Infectious mononucleosis and risk for multiple sclerosis: A meta-analysis
    • Thacker EL, Mirzaei F, Ascherio A. Infectious mononucleosis and risk for multiple sclerosis: a meta-analysis. Ann Neurol 2006; 59: 499-503.
    • (2006) Ann Neurol , vol.59 , pp. 499-503
    • Thacker, E.L.1    Mirzaei, F.2    Ascherio, A.3
  • 15
    • 41849096980 scopus 로고    scopus 로고
    • Varicella-zoster virus in cerebrospinal fluid at relapses of multiple sclerosis
    • Sotelo J, Martinez-Palomo A, Ordonez G, Pineda B. Varicella-zoster virus in cerebrospinal fluid at relapses of multiple sclerosis. Ann Neurol 2008; 63: 303-311
    • (2008) Ann Neurol , vol.63 , pp. 303-311
    • Sotelo, J.1    Martinez-Palomo, A.2    Ordonez, G.3    Pineda, B.4
  • 16
    • 0015232447 scopus 로고
    • Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy
    • Padgett BL, Walker DL, ZuRhein GM, Eckroade RJ, Dessel BH. Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1971; 1: 1257-1260
    • (1971) Lancet , vol.1 , pp. 1257-1260
    • Padgett, B.L.1    Walker, D.L.2    ZuRhein, G.M.3    Eckroade, R.J.4    Dessel, B.H.5
  • 17
    • 0034119798 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy: JC virus induced demyelination in the immune compromised host
    • Hou J, Major EO. Progressive multifocal leukoencephalopathy: JC virus induced demyelination in the immune compromised host. J Neurovirol 2000; 6(Suppl 2): S98-S100. (Pubitemid 30348921)
    • (2000) Journal of NeuroVirology , vol.6 , Issue.SUPPL. 2
    • Hou, J.1    Major, E.O.2
  • 19
    • 0032558184 scopus 로고    scopus 로고
    • Guillain-Barre syndrome
    • Hahn AF. Guillain-Barre syndrome. Lancet 1998; 352: 635-641
    • (1998) Lancet , vol.352 , pp. 635-641
    • Hahn, A.F.1
  • 21
    • 42649138374 scopus 로고    scopus 로고
    • Philadelphia: Lippincott-Raven Publishers
    • McIntosh K. Fields Virology, Coronaviruses. Philadelphia: Lippincott-Raven Publishers 1996; pp. 1095-1104
    • (1996) Fields Virology, Coronaviruses , pp. 1095-1104
    • McIntosh, K.1
  • 22
    • 0001688511 scopus 로고
    • A murine virus (JHM) causing disseminated encephalomyelitis with extensive destruction of myelin
    • Cheever FS, Daniels JB, Pappenheimer AM, Bailey OT. A murine virus (JHM) causing disseminated encephalomyelitis with extensive destruction of myelin. J Exp Med 1949; 90: 181-210.
    • (1949) J Exp Med , vol.90 , pp. 181-210
    • Cheever, F.S.1    Daniels, J.B.2    Pappenheimer, A.M.3    Bailey, O.T.4
  • 24
    • 0026482905 scopus 로고
    • Coronavirus species specificity: Murine coronavirus binds to a mouse-specific epitope on its carcinoembryonic antigen-related receptor glycoprotein
    • Compton SR, Stephensen CB, Snyder SW, Weismiller DG, Holmes KV. Coronavirus species specificity: murine coronavirus binds to a mouse-specific epitope on its carcinoembryonic antigen-related receptor glycoprotein. J Virol 1992; 66: 7420-7428
    • (1992) J Virol , vol.66 , pp. 7420-7428
    • Compton, S.R.1    Stephensen, C.B.2    Snyder, S.W.3    Weismiller, D.G.4    Holmes, K.V.5
  • 25
    • 0025352657 scopus 로고
    • Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a nonfunctional, homologous protein in MHV-resistant SJL/J mice
    • Williams RK, Jiang GS, Snyder SW, Frana MF, Holmes KV. Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a nonfunctional, homologous protein in MHV-resistant SJL/J mice. J Virol 1990; 64: 3817-3823
    • (1990) J Virol , vol.64 , pp. 3817-3823
    • Williams, R.K.1    Jiang, G.S.2    Snyder, S.W.3    Frana, M.F.4    Holmes, K.V.5
  • 26
    • 0141856400 scopus 로고    scopus 로고
    • Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein
    • DOI 10.1128/JVI.77.19.10260-10269.2003
    • Ontiveros E, Kim TS, Gallagher TM, Perlman S. Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein. J Virol 2003; 77: 10260-10269 (Pubitemid 37129669)
    • (2003) Journal of Virology , vol.77 , Issue.19 , pp. 10260-10269
    • Ontiveros, E.1    Kim, T.S.2    Gallagher, T.M.3    Perlman, S.4
  • 27
    • 33745796824 scopus 로고    scopus 로고
    • Both spike and background genes contribute to murine coronavirus neurovirulence
    • DOI 10.1128/JVI.00432-06
    • Iacono KT, Kazi L, Weiss SR. Both spike and background genes contribute to murine coronavirus neurovirulence. J Virol 2006; 80: 6834-6843 (Pubitemid 44025183)
    • (2006) Journal of Virology , vol.80 , Issue.14 , pp. 6834-6843
    • Iacono, K.T.1    Kazi, L.2    Weiss, S.R.3
  • 28
    • 0036396869 scopus 로고    scopus 로고
    • Murine coronavirus spike glycoprotein mediates degree of viral spread, inflammation, and virus-induced immunopathology in the central nervous system
    • Phillips JJ, Chua MM, Rall GF, Weiss SR. Murine coronavirus spike glycoprotein mediates degree of viral spread, inflammation, and virus-induced immunopathology in the central nervous system. Virology 2002; 301: 109-120
    • (2002) Virology , vol.301 , pp. 109-120
    • Phillips, J.J.1    Chua, M.M.2    Rall, G.F.3    Weiss, S.R.4
  • 29
    • 4444321560 scopus 로고    scopus 로고
    • -/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59
    • DOI 10.1128/JVI.78.18.10156-10165.2004
    • Hemmila E, Turbide C, Olson M, Jothy S, Holmes KV, Beauchemin N. Ceacam1a-/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59. J Virol 2004; 78: 10156-10165 (Pubitemid 39187133)
    • (2004) Journal of Virology , vol.78 , Issue.18 , pp. 10156-10165
    • Hemmila, E.1    Turbide, C.2    Olson, M.3    Jothy, S.4    Holmes, K.V.5    Beauchemin, N.6
  • 30
    • 18144377732 scopus 로고    scopus 로고
    • Receptor-independent spread of a highly neurotropic murine coronavirus JHMV strain from initially infected microglial cells in mixed neural cultures
    • DOI 10.1128/JVI.79.10.6102-6110.2005
    • Nakagaki K, Nakagaki K, Taguchi F. Receptor-independent spread of a highly neurotropic murine coronavirus JHMV strain from initially infected microglial cells in mixed neural cultures. J Virol 2005; 79: 6102-6110 (Pubitemid 40617215)
    • (2005) Journal of Virology , vol.79 , Issue.10 , pp. 6102-6110
    • Nakagaki, K.1    Nakagaki, K.2    Taguchi, F.3
  • 31
    • 1542347897 scopus 로고    scopus 로고
    • Requirements for CEACAMs and cholesterol during murine coronavirus cell entry
    • Thorp EB, Gallagher TM. Requirements for CEACAMs and cholesterol during murine coronavirus cell entry. J Virol 2004; 78: 2682-2692
    • (2004) J Virol , vol.78 , pp. 2682-2692
    • Thorp, E.B.1    Gallagher, T.M.2
  • 32
    • 37849044884 scopus 로고    scopus 로고
    • The spike glycoprotein of murine coronavirus MHV-JHM mediates receptor-independent infection and spread in the central nervous systems of Ceacam1a-/-Mice
    • Miura TA, Travanty EA, Oko L, et al. The spike glycoprotein of murine coronavirus MHV-JHM mediates receptor-independent infection and spread in the central nervous systems of Ceacam1a-/-Mice. J Virol 2008; 82: 755-763
    • (2008) J Virol , vol.82 , pp. 755-763
    • Miura, T.A.1    Travanty, E.A.2    Oko, L.3
  • 33
    • 0029608722 scopus 로고
    • A pregnancy-specific glycoprotein is expressed in the brain and serves as a receptor for mouse hepatitis virus
    • Chen DS, Asanaka M, Yokomori K, et al. A pregnancy-specific glycoprotein is expressed in the brain and serves as a receptor for mouse hepatitis virus. Proc Natl Acad Sci USA 1995; 92: 12095-12099
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12095-12099
    • Chen, D.S.1    Asanaka, M.2    Yokomori, K.3
  • 34
    • 0026793068 scopus 로고
    • Cell receptor-independent infection by a neurotropic murine coronavirus
    • Gallagher TM, Buchmeier MJ, Perlman S. Cell receptor-independent infection by a neurotropic murine coronavirus. Virology 1992; 191: 517-522
    • (1992) Virology , vol.191 , pp. 517-522
    • Gallagher, T.M.1    Buchmeier, M.J.2    Perlman, S.3
  • 35
    • 0028788246 scopus 로고
    • Tissue and cellular distribution of an adhesion molecule in the carcinoembryonic antigen family that serves as a receptor for mouse hepatitis virus
    • Godfraind C, Langreth SG, Cardellichio CB, et al. Tissue and cellular distribution of an adhesion molecule in the carcinoembryonic antigen family that serves as a receptor for mouse hepatitis virus. Lab Invest 1995; 73: 615-627
    • (1995) Lab Invest , vol.73 , pp. 615-627
    • Godfraind, C.1    Langreth, S.G.2    Cardellichio, C.B.3
  • 36
    • 0031446816 scopus 로고    scopus 로고
    • Role of virus receptor-bearing endothelial cells of the blood-brain barrier in preventing the spread of mouse hepatitis virus-A59 into the central nervous system
    • Godfraind C, Havaux N, Holmes KV, Coutelier JP. Role of virus receptor-bearing endothelial cells of the blood-brain barrier in preventing the spread of mouse hepatitis virus-A59 into the central nervous system. J Neurovirol 1997; 3: 428-434 (Pubitemid 28041142)
    • (1997) Journal of NeuroVirology , vol.3 , Issue.6 , pp. 428-434
    • Godfraind, C.1    Havaux, N.2    Holmes, K.V.3    Coutelier, J.-P.4
  • 37
    • 3142716057 scopus 로고    scopus 로고
    • Expression of the mouse hepatitis virus receptor by central nervous system microglia
    • DOI 10.1128/JVI.78.14.7828-7832.2004
    • Ramakrishna C, Bergmann CC, Holmes KV, Stohlman SA. Expression of the mouse hepatitis virus receptor by central nervous system microglia. J Virol 2004; 78: 7828-7832 (Pubitemid 38915930)
    • (2004) Journal of Virology , vol.78 , Issue.14 , pp. 7828-7832
    • Ramakrishna, C.1    Bergmann, C.C.2    Holmes, K.V.3    Stohlman, S.A.4
  • 38
    • 0026710667 scopus 로고
    • Sequential infection of glial cells by the murine hepatitis virus JHM strain (MHV-4) leads to a characteristic distribution of demyelination
    • Wang FI, Hinton DR, Gilmore W, Trousdale MD, Fleming JO. Sequential infection of glial cells by the murine hepatitis virus JHM strain (MHV-4) leads to a characteristic distribution of demyelination. Lab Invest 1992; 66: 744-754
    • (1992) Lab Invest , vol.66 , pp. 744-754
    • Wang, F.I.1    Hinton, D.R.2    Gilmore, W.3    Trousdale, M.D.4    Fleming, J.O.5
  • 39
    • 0030461287 scopus 로고    scopus 로고
    • Pathogenesis of mouse hepatitis virus-induced demyelination
    • Houtman JJ, Fleming JO. Pathogenesis of mouse hepatitis virus-induced demyelination. J Neurovirol 1996; 2: 361-376 (Pubitemid 27011089)
    • (1996) Journal of NeuroVirology , vol.2 , Issue.6 , pp. 361-376
    • Houtman, J.J.1    Fleming, J.O.2
  • 40
    • 0031975791 scopus 로고    scopus 로고
    • Dynamic regulation of α- and β-chemokine expression in the central nervous system during mouse hepatitis virus-induced demyelinating disease
    • Lane TE, Asensio VC, Yu N, Paoletti AD, Campbell IL, Buchmeier MJ. Dynamic regulation of alpha- and beta-chemokine expression in the central nervous system during mouse hepatitis virus-induced demyelinating disease. J Immunol 1998; 160: 970-978 (Pubitemid 28049342)
    • (1998) Journal of Immunology , vol.160 , Issue.2 , pp. 970-978
    • Lane, T.E.1    Asensio, V.C.2    Yu, N.3    Paoletti, A.D.4    Campbell, I.L.5    Buchmeier, M.J.6
  • 41
    • 0027941162 scopus 로고
    • Cytokine induction during T-cell-mediated clearance of mouse hepatitis virus from neurons in vivo
    • Pearce BD, Hobbs MV, McGraw TS, Buchmeier MJ. Cytokine induction during T-cell-mediated clearance of mouse hepatitis virus from neurons in vivo. J Virol 1994; 68: 5483-5495 (Pubitemid 24258561)
    • (1994) Journal of Virology , vol.68 , Issue.9 , pp. 5483-5495
    • Pearce, B.D.1    Hobbs, M.V.2    Mcgraw, T.S.3    Buchmeier, M.J.4
  • 42
    • 0030787902 scopus 로고    scopus 로고
    • Kinetics of cytokine mRNA expression in the central nervous system following lethal and nonlethal coronavirus-induced acute encephalomyelitis
    • Parra B, Hinton DR, Lin MT, Cua DJ, Stohlman SA. Kinetics of cytokine mRNA expression in the central nervous system following lethal and nonlethal coronavirus-induced acute encephalomyelitis. Virology 1997; 233: 260-270
    • (1997) Virology , vol.233 , pp. 260-270
    • Parra, B.1    Hinton, D.R.2    Lin, M.T.3    Cua, D.J.4    Stohlman, S.A.5
  • 43
    • 0031060311 scopus 로고    scopus 로고
    • Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis
    • Lin MT, Stohlman SA, Hinton DR. Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis. J Virol 1997; 71: 383-391 (Pubitemid 26412303)
    • (1997) Journal of Virology , vol.71 , Issue.1 , pp. 383-391
    • Lin, M.T.1    Stohlman, S.A.2    Hinton, D.R.3
  • 45
    • 0033900298 scopus 로고    scopus 로고
    • Role of viral persistence in retaining CD8(+) T cells within the central nervous system
    • Marten NW, Stohlman SA, CC Bergmann. Role of viral persistence in retaining CD8(+) T cells within the central nervous system. J Virol 2000; 74: 7903-7910
    • (2000) J Virol , vol.74 , pp. 7903-7910
    • Marten, N.W.1    Stohlman, S.A.2    Bergmann, C.C.3
  • 47
    • 0028297362 scopus 로고
    • Coronavirus-induced demyelination occurs in the presence of virus-specific cytotoxic T cells
    • DOI 10.1006/viro.1994.1237
    • Castro RF, Evans GD, Jaszewski A, Perlman S. Coronavirus-induced demyelination occurs in the presence of virus-specific cytotoxic T cells. Virology 1994; 200: 733-743 (Pubitemid 24146550)
    • (1994) Virology , vol.200 , Issue.2 , pp. 733-743
    • Castro, R.F.1    Evans, G.D.2    Jaszewski, A.3    Perlman, S.4
  • 48
    • 0035478591 scopus 로고    scopus 로고
    • Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple sclerosis
    • Liu MT, Keirstead HS, Lane TE. Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple sclerosis. J Immunol 2001; 167: 4091-4097
    • (2001) J Immunol , vol.167 , pp. 4091-4097
    • Liu, M.T.1    Keirstead, H.S.2    Lane, T.E.3
  • 49
    • 0021344138 scopus 로고
    • Murine hepatitis virus-4 (strain JHM)-induced neurologic disease is modulated in vivo by monoclonal antibody
    • Buchmeier MJ, Lewicki HA, Talbot PJ, Knobler RL. Murine hepatitis virus-4 (strain JHM)-induced neurologic disease is modulated in vivo by monoclonal antibody. Virology 1984; 132: 261-270
    • (1984) Virology , vol.132 , pp. 261-270
    • Buchmeier, M.J.1    Lewicki, H.A.2    Talbot, P.J.3    Knobler, R.L.4
  • 50
    • 0021080239 scopus 로고
    • Antigenic relationships of murine coronaviruses: Analysis using monoclonal antibodies to JHM (MHV-4) virus
    • Fleming JO, Stohlman SA, Harmon RC, Lai MM, Frelinger JA, Weiner LP. Antigenic relationships of murine coronaviruses: analysis using monoclonal antibodies to JHM (MHV-4) virus. Virology 1983; 131: 296-307.
    • (1983) Virology , vol.131 , pp. 296-307
    • Fleming, J.O.1    Stohlman, S.A.2    Harmon, R.C.3    Lai, M.M.4    Frelinger, J.A.5    Weiner, L.P.6
  • 51
    • 37349029705 scopus 로고    scopus 로고
    • Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells
    • DOI 10.1128/JVI.01794-07
    • Ireland DD, Stohlman SA, Hinton DR, Atkinson R, Bergmann CC. Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells. J Virol 2008; 82: 300-310 (Pubitemid 350309146)
    • (2008) Journal of Virology , vol.82 , Issue.1 , pp. 300-310
    • Ireland, D.D.C.1    Stohlman, S.A.2    Hinton, D.R.3    Atkinson, R.4    Bergmann, C.C.5
  • 52
  • 54
    • 1242319450 scopus 로고    scopus 로고
    • Differential regulation of innate and adaptive immune responses in viral encephalitis
    • Rempel JD, Murray SJ, Meisner J, Buchmeier MJ. Differential regulation of innate and adaptive immune responses in viral encephalitis. Virology 2004; 318: 381-392
    • (2004) Virology , vol.318 , pp. 381-392
    • Rempel, J.D.1    Murray, S.J.2    Meisner, J.3    Buchmeier, M.J.4
  • 55
    • 0028826296 scopus 로고
    • Activation of astrocytes in the spinal cord of mice chronically infected with a neurotropic coronavirus
    • Sun N, Grzybicki D, Castro RF, Murphy S, Perlman S. Activation of astrocytes in the spinal cord of mice chronically infected with a neurotropic coronavirus. Virology 1995; 213: 482-493
    • (1995) Virology , vol.213 , pp. 482-493
    • Sun, N.1    Grzybicki, D.2    Castro, R.F.3    Murphy, S.4    Perlman, S.5
  • 56
    • 16244409276 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis
    • DOI 10.1128/JVI.79.8.4764-4773.2005
    • Zhou J, Marten NW, Bergmann CC, Macklin WB, Hinton DR, Stohlman SA. Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis. J Virol 2005; 79: 4764-4773 (Pubitemid 40464227)
    • (2005) Journal of Virology , vol.79 , Issue.8 , pp. 4764-4773
    • Zhou, J.1    Marten, N.W.2    Bergmann, C.C.3    Macklin, W.B.4    Hinton, D.R.5    Stohlman, S.A.6
  • 57
    • 0036314877 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection
    • DOI 10.1128/JVI.76.15.7374-7384.2002
    • Zhou J, Stohlman SA, Atkinson R, Hinton DR, Marten NW. Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection. J Virol 2002; 76: 7374-7384 (Pubitemid 34760960)
    • (2002) Journal of Virology , vol.76 , Issue.15 , pp. 7374-7384
    • Zhou, J.1    Stohlman, S.A.2    Atkinson, R.3    Hinton, D.R.4    Marten, N.W.5
  • 58
    • 0035987451 scopus 로고    scopus 로고
    • Mouse hepatitis virus infection of the central nervous system: Chemokine-mediated regulation of host defense and disease
    • Glass WG, Chen BP, Liu MT, Lane TE. Mouse hepatitis virus infection of the central nervous system: chemokine-mediated regulation of host defense and disease. Viral Immunol 2002; 15: 261-272
    • (2002) Viral Immunol , vol.15 , pp. 261-272
    • Glass, W.G.1    Chen, B.P.2    Liu, M.T.3    Lane, T.E.4
  • 59
    • 38349185339 scopus 로고    scopus 로고
    • Maturation and localization of macrophages and microglia during infection with a neurotropic murine coronavirus
    • Templeton SP, Kim TS, O'Malley K, Perlman S. Maturation and localization of macrophages and microglia during infection with a neurotropic murine coronavirus. Brain Pathol 2008; 18: 40-51.
    • (2008) Brain Pathol , vol.18 , pp. 40-51
    • Templeton, S.P.1    Kim, T.S.2    O'Malley, K.3    Perlman, S.4
  • 60
    • 33744900123 scopus 로고    scopus 로고
    • Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells
    • Zuo J, Stohlman SA, Hoskin JB, Hinton DR, Atkinson R, Bergmann CC. Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells. Virology 2006; 350: 206-215
    • (2006) Virology , vol.350 , pp. 206-215
    • Zuo, J.1    Stohlman, S.A.2    Hoskin, J.B.3    Hinton, D.R.4    Atkinson, R.5    Bergmann, C.C.6
  • 61
    • 0035405886 scopus 로고    scopus 로고
    • Metalloproteinases in biology and pathology of the nervous system
    • Yong VW, Power C, Forsyth P, Edwards DR. Metalloproteinases in biology and pathology of the nervous system. Nat Rev Neurosci 2001; 2: 502-511
    • (2001) Nat Rev Neurosci , vol.2 , pp. 502-511
    • Yong, V.W.1    Power, C.2    Forsyth, P.3    Edwards, D.R.4
  • 62
    • 0346035761 scopus 로고    scopus 로고
    • Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis
    • Zhou J, Stohlman SA, Hinton DR, Marten NW. Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis. J Immunol 2003; 170: 3331-3336 (Pubitemid 36302212)
    • (2003) Journal of Immunology , vol.170 , Issue.6 , pp. 3331-3336
    • Zhou, J.1    Stohlman, S.A.2    Hinton, D.R.3    Marten, N.W.4
  • 63
    • 0032813555 scopus 로고    scopus 로고
    • Depletion of blood-borne macrophages does not reduce demyelination in mice infected with a neurotropic coronavirus
    • Xue S, Sun N, Van Rooijen N, Perlman S. Depletion of blood-borne macrophages does not reduce demyelination in mice infected with a neurotropic coronavirus. J Virol 1999; 73: 6327-6334 (Pubitemid 29327809)
    • (1999) Journal of Virology , vol.73 , Issue.8 , pp. 6327-6334
    • Xue, S.1    Sun, N.2    Van Rooijen, N.3    Perlman, S.4
  • 64
    • 0037320017 scopus 로고    scopus 로고
    • +-T-cell expansion and trafficking following central nervous system infection
    • DOI 10.1128/JVI.77.4.2775-2778.2003
    • Marten NW, Stohlman SA, Zhou J, Bergmann CC. Kinetics of virus-specific CD8+ -T-cell expansion and trafficking following central nervous system infection. J Virol 2003; 77: 2775-2778 (Pubitemid 36222805)
    • (2003) Journal of Virology , vol.77 , Issue.4 , pp. 2775-2778
    • Marten, N.W.1    Stohlman, S.A.2    Zhou, J.3    Bergmann, C.C.4
  • 65
    • 0037443570 scopus 로고    scopus 로고
    • Perforin-mediated effector function within the central nervous system requires IFN-γ-mediated MHC up-regulation
    • Bergmann CC, Parra B, Hinton DR, Chandran R, Morrison M, Stohlman SA. Perforin-mediated effector function within the central nervous system requires IFN-gamma-mediated MHC upregulation. J Immunol 2003; 170: 3204-3213 (Pubitemid 36302198)
    • (2003) Journal of Immunology , vol.170 , Issue.6 , pp. 3204-3213
    • Bergmann, C.C.1    Parra, B.2    Hinton, D.R.3    Chandran, R.4    Morrison, M.5    Stohlman, S.A.6
  • 66
    • 45749109378 scopus 로고    scopus 로고
    • Generation of a Protective T-Cell Response Following Coronavirus Infection of the Central Nervous System Is Not Dependent on IL-12/23 Signaling
    • Held KS, Glass WG, Orlovsky YI, et al. Generation of a Protective T-Cell Response Following Coronavirus Infection of the Central Nervous System Is Not Dependent on IL-12/23 Signaling. Viral Immunol 2008; 21: 173-188
    • (2008) Viral Immunol , vol.21 , pp. 173-188
    • Held, K.S.1    Glass, W.G.2    Orlovsky, Y.I.3
  • 67
    • 18844476793 scopus 로고    scopus 로고
    • A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination
    • Lane TE, Liu MT, Chen BP, et al. A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination. J Virol 2000; 74: 1415-1424
    • (2000) J Virol , vol.74 , pp. 1415-1424
    • Lane, T.E.1    Liu, M.T.2    Chen, B.P.3
  • 68
    • 31544476315 scopus 로고    scopus 로고
    • Coronavirus infection of the central nervous system: Host-virus stand-off
    • Bergmann CC, Lane TE, Stohlman SA. Coronavirus infection of the central nervous system: host-virus stand-off. Nat Rev Microbiol 2006; 4: 121-132
    • (2006) Nat Rev Microbiol , vol.4 , pp. 121-132
    • Bergmann, C.C.1    Lane, T.E.2    Stohlman, S.A.3
  • 69
    • 0033568030 scopus 로고    scopus 로고
    • + T cells during viral persistence in the central nervous system
    • Bergmann CC, Altman JD, Hinton D, Stohlman SA. Inverted immunodominance and impaired cytolytic function of CD8+ T cells during viral persistence in the central nervous system. J Immunol 1999; 163: 3379-3387 (Pubitemid 29431840)
    • (1999) Journal of Immunology , vol.163 , Issue.6 , pp. 3379-3387
    • Bergmann, C.C.1    Altman, J.D.2    Hinton, D.3    Stohlman, S.A.4
  • 70
    • 40149088008 scopus 로고    scopus 로고
    • NKG2D receptor signaling enhances cytolytic activity by virus-specific CD8+ T cells: Evidence for a protective role in virus-induced encephalitis
    • Walsh KB, Lanier LL, Lane TE. NKG2D receptor signaling enhances cytolytic activity by virus-specific CD8+ T cells: evidence for a protective role in virus-induced encephalitis. J Virol 2008; 82: 3031-3044
    • (2008) J Virol , vol.82 , pp. 3031-3044
    • Walsh, K.B.1    Lanier, L.L.2    Lane, T.E.3
  • 72
    • 0034664053 scopus 로고    scopus 로고
    • CD4 and CD8 T cells have redundant but not identical roles in virus- Induced demyelination
    • Wu GF, Dandekar AA, Pewe L, Perlman S. CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination. J Immunol 2000; 165: 2278-2286 (Pubitemid 30643179)
    • (2000) Journal of Immunology , vol.165 , Issue.4 , pp. 2278-2286
    • Wu, G.F.1    Dandekar, A.A.2    Pewe, L.3    Perlman, S.4
  • 73
    • 0842282849 scopus 로고    scopus 로고
    • Perforin and Gamma Interferon-Mediated Control of Coronavirus Central Nervous System Infection by CD8 T Cells in the Absence of CD4 T Cells
    • DOI 10.1128/JVI.78.4.1739-1750.2004
    • Bergmann CC, Parra B, Hinton DR, Ramakrishna C, Dowdell KC, Stohlman SA. Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells. J Virol 2004; 78: 1739-1750 (Pubitemid 38176706)
    • (2004) Journal of Virology , vol.78 , Issue.4 , pp. 1739-1750
    • Bergmann, C.C.1    Parra, B.2    Hinton, D.R.3    Ramakrishna, C.4    Dowdell, K.C.5    Stohlman, S.A.6
  • 74
    • 0032521017 scopus 로고    scopus 로고
    • CTL effector function within the central nervous system requires CD4+ T cells
    • Stohlman SA, Bergmann CC, Lin MT, Cua DJ, Hinton DR. CTL effector function within the central nervous system requires CD4+ T cells. J Immunol 1998; 160: 2896-2904
    • (1998) J Immunol , vol.160 , pp. 2896-2904
    • Stohlman, S.A.1    Bergmann, C.C.2    Lin, M.T.3    Cua, D.J.4    Hinton, D.R.5
  • 75
    • 17844371983 scopus 로고    scopus 로고
    • Maintenance of CD8+ T cells during acute viral infection of the central nervous system requires CD4+ T cells but not interleukin-2
    • Zhou J, Hinton DR, Stohlman SA, Liu CP, Zhong L, Marten NW. Maintenance of CD8+ T cells during acute viral infection of the central nervous system requires CD4+ T cells but not interleukin-2. Viral Immunol 2005; 18: 162-169
    • (2005) Viral Immunol , vol.18 , pp. 162-169
    • Zhou, J.1    Hinton, D.R.2    Stohlman, S.A.3    Liu, C.P.4    Zhong, L.5    Marten, N.W.6
  • 76
    • 0037087259 scopus 로고    scopus 로고
    • Recruitment kinetics and composition of antibody-secreting cells within the central nervous system following viral encephalomyelitis
    • Tschen SI, Bergmann CC, Ramakrishna C, Morales S, Atkinson R, Stohlman SA. Recruitment kinetics and composition of antibody-secreting cells within the central nervous system following viral encephalomyelitis. J Immunol 2002; 168: 2922-2929 (Pubitemid 34211672)
    • (2002) Journal of Immunology , vol.168 , Issue.6 , pp. 2922-2929
    • Tschen, S.-I.1    Bergmann, C.C.2    Ramakrishna, C.3    Morales, S.4    Atkinson, R.5    Stohlman, S.A.6
  • 77
    • 0037385987 scopus 로고    scopus 로고
    • Control of central nervous system viral persistence by neutralizing antibody
    • DOI 10.1128/JVI.77.8.4670-4678.2003
    • Ramakrishna C, Bergmann CC, Atkinson R, Stohlman SA. Control of central nervous system viral persistence by neutralizing antibody. J Virol 2003; 77: 4670-4678 (Pubitemid 36402816)
    • (2003) Journal of Virology , vol.77 , Issue.8 , pp. 4670-4678
    • Ramakrishna, C.1    Bergmann, C.C.2    Atkinson, R.3    Stohlman, S.A.4
  • 78
    • 0036467341 scopus 로고    scopus 로고
    • Mechanisms of central nervous system viral persistence: The critical role of antibody and B cells
    • Ramakrishna C, Stohlman SA, Atkinson RD, Shlomchik MJ, Bergmann CC. Mechanisms of central nervous system viral persistence: the critical role of antibody and B cells. J Immunol 2002; 168: 1204-1211 (Pubitemid 34094486)
    • (2002) Journal of Immunology , vol.168 , Issue.3 , pp. 1204-1211
    • Ramakrishna, C.1    Stohlman, S.A.2    Atkinson, R.D.3    Shlomchik, M.J.4    Bergmann, C.C.5
  • 80
    • 0028997972 scopus 로고
    • Evolution of mouse hepatitis virus (MHV) during chronic infection: Quasispecies nature of the persisting MHV RNA
    • Adami C, Pooley J, Glomb J, et al. Evolution of mouse hepatitis virus (MHV) during chronic infection: quasispecies nature of the persisting MHV RNA. Virology 1995; 209: 337-346
    • (1995) Virology , vol.209 , pp. 337-346
    • Adami, C.1    Pooley, J.2    Glomb, J.3
  • 81
    • 0032503248 scopus 로고    scopus 로고
    • Variability of persisting MHV RNA sequences constituting immune and replication-relevant domains
    • Bergmann C, Dimacali E, Stohl S, et al. Variability of persisting MHV RNA sequences constituting immune and replication-relevant domains. Virology 1998; 244: 563-572
    • (1998) Virology , vol.244 , pp. 563-572
    • Bergmann, C.1    Dimacali, E.2    Stohl, S.3
  • 82
    • 0032845113 scopus 로고    scopus 로고
    • Macrophage infiltration, but not apoptosis, is correlated with immune- Mediated demyelination following murine infection with a neurotropic coronavirus
    • Wu GF, Perlman S. Macrophage infiltration, but not apoptosis, is correlated with immune-mediated demyelination following murine infection with a neurotropic coronavirus. J Virol 1999; 73: 8771-8780 (Pubitemid 29441742)
    • (1999) Journal of Virology , vol.73 , Issue.10 , pp. 8771-8780
    • Wu, G.F.1    Perlman, S.2
  • 83
    • 0036306816 scopus 로고    scopus 로고
    • Neither B cells nor T cells are required for CNS demyelination in mice persistently infected with MHV-A59
    • DOI 10.1080/13550280290049697
    • Matthews AE, Lavi E, Weiss SR, Paterson Y. Neither B cells nor T cells are required for CNS demyelination in mice persistently infected with MHV-A59. J Neurovirol 2002; 8: 257-264 (Pubitemid 34732707)
    • (2002) Journal of NeuroVirology , vol.8 , Issue.3 , pp. 257-264
    • Matthews, A.E.1    Lavi, E.2    Weiss, S.R.3    Paterson, Y.4
  • 85
    • 0036093882 scopus 로고    scopus 로고
    • Murine hepatitis virus - A model for virus-induced CNS demyelination
    • DOI 10.1080/13550280290049534
    • Matthews AE, Weiss SR, Paterson Y. Murine hepatitis virus - a model for virus-induced CNS demyelination. J Neurovirol 2002; 8: 76-85. (Pubitemid 34520889)
    • (2002) Journal of NeuroVirology , vol.8 , Issue.2 , pp. 76-85
    • Matthews, A.E.1    Weiss, S.R.2    Paterson, Y.3
  • 86
    • 0030796646 scopus 로고    scopus 로고
    • Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading
    • Miller SD, Vanderlugt CL, Begolka WS, et al. Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading. Nat Med 1997; 3: 1133-1136
    • (1997) Nat Med , vol.3 , pp. 1133-1136
    • Miller, S.D.1    Vanderlugt, C.L.2    Begolka, W.S.3
  • 88
    • 16244417773 scopus 로고    scopus 로고
    • Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
    • DOI 10.1038/nm1202
    • McMahon EJ, Bailey SL, Castenada CV, Waldner H, Miller SD. Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nat Med 2005; 11: 335-339 (Pubitemid 40460563)
    • (2005) Nature Medicine , vol.11 , Issue.3 , pp. 335-339
    • McMahon, E.J.1    Bailey, S.L.2    Castenada, C.V.3    Waldner, H.4    Miller, S.D.5
  • 89
    • 0030899404 scopus 로고    scopus 로고
    • Diversity and plasticity of self recognition during the development of multiple sclerosis
    • Tuohy VK, Yu M, Weinstock-Guttman B, Kinkel RP. Diversity and plasticity of self recognition during the development of multiple sclerosis. J Clin Invest 1997; 99: 1682-1690 (Pubitemid 27163819)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.7 , pp. 1682-1690
    • Tuohy, V.K.1    Yu, M.2    Weinstock-Guttman, B.3    Kinkel, R.P.4
  • 90
    • 0033976207 scopus 로고    scopus 로고
    • Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: Epitope spreading versus clonal persistence
    • Goebels N, Hofstetter H, Schmidt S, Brunner C, Wekerle H, Hohlfeld R. Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence. Brain 2000; 123 Pt 3: 508-518
    • (2000) Brain , vol.123 , Issue.PART 3 , pp. 508-518
    • Goebels, N.1    Hofstetter, H.2    Schmidt, S.3    Brunner, C.4    Wekerle, H.5    Hohlfeld, R.6
  • 91
    • 0033526109 scopus 로고    scopus 로고
    • Spontaneous regression of primary autoreactivity during chronic progression of experimental autoimmune encephalomyelitis and multiple sclerosis
    • DOI 10.1084/jem.189.7.1033
    • Tuohy VK, Yu M, Yin L, Kawczak JA, Kinkel RP. Spontaneous regression of primary autoreactivity during chronic progression of experimental autoimmune encephalomyelitis and multiple sclerosis. J Exp Med 1999; 189:1033-1042 (Pubitemid 29169820)
    • (1999) Journal of Experimental Medicine , vol.189 , Issue.7 , pp. 1033-1042
    • Tuohy, V.K.1    Yu, M.2    Yin, L.3    Kawczak, J.A.4    Kinkel, R.P.5
  • 92
    • 1642317079 scopus 로고    scopus 로고
    • Antibody targeting of the CC chemokine ligand 5 results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis
    • Glass WG, Hickey MJ, Hardison JL, Liu MT, Manning JE, Lane TE. Antibody targeting of the CC chemokine ligand 5 results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis. J Immunol 2004; 172: 4018-4025
    • (2004) J Immunol , vol.172 , pp. 4018-4025
    • Glass, W.G.1    Hickey, M.J.2    Hardison, J.L.3    Liu, M.T.4    Manning, J.E.5    Lane, T.E.6
  • 93
    • 0035885037 scopus 로고    scopus 로고
    • Reduced macrophage infiltration and demyelination in mice lacking the chemokine receptor CCR5 following infection with a neurotropic coronavirus
    • Glass WG, Liu MT, Kuziel WA, Lane TE. Reduced macrophage infiltration and demyelination in mice lacking the chemokine receptor CCR5 following infection with a neurotropic coronavirus. Virology 2001; 288: 8-17.
    • (2001) Virology , vol.288 , pp. 8-17
    • Glass, W.G.1    Liu, M.T.2    Kuziel, W.A.3    Lane, T.E.4
  • 94
    • 0036633675 scopus 로고    scopus 로고
    • CD4 T-cell-mediated demyelination is increased in the absence of gamma interferon in mice infected with mouse hepatitis virus
    • Pewe L, Haring J, Perlman S. CD4 T-cell-mediated demyelination is increased in the absence of gamma interferon in mice infected with mouse hepatitis virus. J Virol 2002; 76: 7329-7333
    • (2002) J Virol , vol.76 , pp. 7329-7333
    • Pewe, L.1    Haring, J.2    Perlman, S.3
  • 95
    • 0037083308 scopus 로고    scopus 로고
    • Cutting edge: CD8 T cell-mediated demyelination is IFN-γdependent in mice infected with a neurotropic coronavirus
    • Pewe L, Perlman S. Cutting edge: CD8 T cell-mediated demyelination is IFN-gamma dependent in mice infected with a neurotropic coronavirus. J Immunol 2002; 168: 1547-1551 (Pubitemid 34135747)
    • (2002) Journal of Immunology , vol.168 , Issue.4 , pp. 1547-1551
    • Pewe, L.1    Perlman, S.2
  • 96
    • 0021072683 scopus 로고
    • Attachment of myelin to coated pits on macrophages in experimental allergic encephalomyelitis
    • DOI 10.1016/0022-510X(83)90167-3
    • Epstein LG, Prineas JW, Raine CS. Attachment of myelin to coated pits on macrophages in experimental allergic encephalomyelitis. J Neurol Sci 1983; 61: 341-348 (Pubitemid 14234262)
    • (1983) Journal of the Neurological Sciences , vol.61 , Issue.3 , pp. 341-348
    • Epstein, L.G.1    Prineas, J.W.2    Raine, C.S.3
  • 97
    • 0013952775 scopus 로고
    • Experimental allergic encephalomyelitis. An electron microscopic study
    • Field EJ, Raine CS. Experimental allergic encephalomyelitis. An electron microscopic study. Am J Pathol 1966; 49: 537-553
    • (1966) Am J Pathol , vol.49 , pp. 537-553
    • Field, E.J.1    Raine, C.S.2
  • 98
    • 0019190570 scopus 로고
    • Further ultrastructural observations of virus morphogenesis and myelin pathology in JHM virus encephalomyelitis
    • Fleury HJ, Sheppard RD, Bornstein MB, Raine CS. Further ultrastructural observations of virus morphogenesis and myelin pathology in JHM virus encephalomyelitis. Neuropathol Appl Neurobiol 1980; 6: 165-179
    • (1980) Neuropathol Appl Neurobiol , vol.6 , pp. 165-179
    • Fleury, H.J.1    Sheppard, R.D.2    Bornstein, M.B.3    Raine, C.S.4
  • 100
    • 15944376943 scopus 로고    scopus 로고
    • Multiple sclerosis: Novel perspectives on newly forming lesions
    • Matute C, Perez-Cerda F. Multiple sclerosis: novel perspectives on newly forming lesions. Trends Neurosci 2005; 28: 173-175
    • (2005) Trends Neurosci , vol.28 , pp. 173-175
    • Matute, C.1    Perez-Cerda, F.2
  • 101
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol 2004; 55: 458-468
    • (2004) Ann Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 102
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis - The plaque and its pathogenesis
    • Frohman EM, Racke MK, Raine CS. Multiple sclerosis - the plaque and its pathogenesis. N Engl J Med 2006; 354: 942-955
    • (2006) N Engl J Med , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 103
    • 0242331747 scopus 로고    scopus 로고
    • Induction of Caspase-Dependent Apoptosis in Cultured Rat Oligodendrocytes by Murine Coronavirus Is Mediated during Cell Entry and Does Not Require Virus Replication
    • DOI 10.1128/JVI.77.22.11952-11963.2003
    • Liu Y, Cai Y, Zhang X. Induction of caspase-dependent apoptosis in cultured rat oligodendrocytes by murine coronavirus is mediated during cell entry and does not require virus replication. J Virol 2003; 77: 11952-11963 (Pubitemid 37339849)
    • (2003) Journal of Virology , vol.77 , Issue.22 , pp. 11952-11963
    • Liu, Y.1    Cai, Y.2    Zhang, X.3
  • 104
    • 33645979338 scopus 로고    scopus 로고
    • Role of the mitochondrial signaling pathway in murine coronavirus-induced oligodendrocyte apoptosis
    • Liu Y, Pu Y, Zhang X. Role of the mitochondrial signaling pathway in murine coronavirus-induced oligodendrocyte apoptosis. J Virol 2006; 80: 395-403.
    • (2006) J Virol , vol.80 , pp. 395-403
    • Liu, Y.1    Pu, Y.2    Zhang, X.3
  • 105
    • 10644293312 scopus 로고    scopus 로고
    • Expression of cellular oncogene Bcl-xL prevents coronavirus-induced cell death and converts acute infection to persistent infection in progenitor rat oligodendrocytes
    • DOI 10.1128/JVI.79.1.47-56.2005
    • Liu Y, X Zhang. Expression of cellular oncogene Bcl-xL prevents coronavirus-induced cell death and converts acute infection to persistent infection in progenitor rat oligodendrocytes. J Virol 2005; 79: 47-56. (Pubitemid 39648362)
    • (2005) Journal of Virology , vol.79 , Issue.1 , pp. 47-56
    • Liu, Y.1    Zhang, X.2
  • 106
    • 33947600095 scopus 로고    scopus 로고
    • Murine coronavirus-induced oligodendrocyte apoptosis is mediated through the activation of the Fas signaling pathway
    • DOI 10.1016/j.virol.2006.10.044, PII S0042682206008002
    • Liu Y, Zhang X. Murine coronavirus-induced oligodendrocyte apoptosis is mediated through the activation of the Fas signaling pathway. Virology 2007; 360: 364-375 (Pubitemid 46482620)
    • (2007) Virology , vol.360 , Issue.2 , pp. 364-375
    • Liu, Y.1    Zhang, X.2
  • 107
    • 0034055609 scopus 로고    scopus 로고
    • Expression of the interferon-γ-inducible chemokines IP-10 and Mig and their receptor, CXCR3, in multiple sclerosis lesions
    • DOI 10.1046/j.1365-2990.2000.026002133.x
    • Simpson JE, Newcombe J, Cuzner ML, Woodroofe MN. Expression of the interferon-gamma-inducible chemokines IP-10 and Mig and their receptor, CXCR3, in multiple sclerosis lesions. Neuropathol Appl Neurobiol 2000; 26: 133-142 (Pubitemid 30251386)
    • (2000) Neuropathology and Applied Neurobiology , vol.26 , Issue.2 , pp. 133-142
    • Simpson, J.E.1    Newcombe, J.2    Cuzner, M.L.3    Woodroofe, M.N.4
  • 108
    • 33644952574 scopus 로고    scopus 로고
    • Differential roles for CXCR3 in CD4+ and CD8+ T cell trafficking following viral infection of the CNS
    • Stiles LN, Hosking MP, Edwards RA, Strieter RM, Lane TE. Differential roles for CXCR3 in CD4+ and CD8+ T cell trafficking following viral infection of the CNS. Eur J Immunol 2006; 36: 613-622
    • (2006) Eur J Immunol , vol.36 , pp. 613-622
    • Stiles, L.N.1    Hosking, M.P.2    Edwards, R.A.3    Strieter, R.M.4    Lane, T.E.5
  • 109
    • 0036533663 scopus 로고    scopus 로고
    • IFN-γ-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking
    • Dufour JH, Dziejman M, Liu MT, Leung JH, Lane TE, Luster AD. IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J Immunol 2002; 168: 3195-3204 (Pubitemid 34256349)
    • (2002) Journal of Immunology , vol.168 , Issue.7 , pp. 3195-3204
    • Dufour, J.H.1    Dziejman, M.2    Liu, M.T.3    Leung, J.H.4    Lane, T.E.5    Luster, A.D.6
  • 110
    • 0033399079 scopus 로고    scopus 로고
    • Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease
    • Hoffman LM, Fife BT, Begolka WS, Miller SD, Karpus WJ. Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease. J Neurovirol 1999; 5: 635-642 (Pubitemid 30032089)
    • (1999) Journal of NeuroVirology , vol.5 , Issue.6 , pp. 635-642
    • Huffman, L.M.1    Fife, B.T.2    Begolka, W.S.3    Miller, S.D.4    Karpus, W.J.5
  • 111
    • 0033952574 scopus 로고    scopus 로고
    • Alterations in cytokine but not chemokine mRNA expression during three distinct Theiler's virus infections
    • DOI 10.1016/S0165-5728(99)00251-9, PII S0165572899002519
    • Theil DJ, Tsunoda I, Libbey JE, Derfuss TJ, Fujinami RS. Alterations in cytokine but not chemokine mRNA expression during three distinct Theiler's virus infections. J Neuroimmunol 2000; 104: 22-30. (Pubitemid 30100534)
    • (2000) Journal of Neuroimmunology , vol.104 , Issue.1 , pp. 22-30
    • Theil, D.J.1    Tsunoda, I.2    Libbey, J.E.3    Derfuss, T.J.4    Fujinami, R.S.5
  • 112
    • 0347337778 scopus 로고    scopus 로고
    • Distinct roles for IP-10/CXCL10 in three animal models, Theiler's virus infection, EAE, and MHV infection, for multiple sclerosis: Implication of differing roles for IP-10
    • DOI 10.1191/1352458504ms982oa
    • Tsunoda I, Lane TE, Blackett J, Fujinami RS. Distinct roles for IP-10/CXCL10 in three animal models, Theiler's virus infection, EAE, and MHV infection, for multiple sclerosis: implication of differing roles for IP-10. Mult Scler 2004; 10: 26-34. (Pubitemid 38100523)
    • (2004) Multiple Sclerosis , vol.10 , Issue.1 , pp. 26-34
    • Tsunoda, I.1    Lane, T.E.2    Blackett, J.3    Fujinami, R.S.4
  • 113
  • 115
    • 42149190657 scopus 로고    scopus 로고
    • CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis
    • Zhang B, Chan YK, Lu B, Diamond MS, Klein RS. CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis. J Immunol 2008; 180: 2641-2649
    • (2008) J Immunol , vol.180 , pp. 2641-2649
    • Zhang, B.1    Chan, Y.K.2    Lu, B.3    Diamond, M.S.4    Klein, R.S.5
  • 116
    • 40449131101 scopus 로고    scopus 로고
    • CXCL9 and CXCL10 expression are critical for control of genital herpes simplex virus type 2 infection through mobilization of HSV-specific CTL and NK cells to the nervous system
    • Thapa M, Welner RS, Pelayo R, Carr DJ. CXCL9 and CXCL10 expression are critical for control of genital herpes simplex virus type 2 infection through mobilization of HSV-specific CTL and NK cells to the nervous system. J Immunol 2008; 180: 1098-1106
    • (2008) J Immunol , vol.180 , pp. 1098-1106
    • Thapa, M.1    Welner, R.S.2    Pelayo, R.3    Carr, D.J.4
  • 117
    • 33746190781 scopus 로고    scopus 로고
    • Both CXCR3 and CXCL10/IFN-inducible protein 10 are required for resistance to primary infection by dengue virus
    • Hsieh MF, Lai SL, Chen JP, et al. Both CXCR3 and CXCL10/IFN-inducible protein 10 are required for resistance to primary infection by dengue virus. J Immunol 2006; 177: 1855-1863
    • (2006) J Immunol , vol.177 , pp. 1855-1863
    • Hsieh, M.F.1    Lai, S.L.2    Chen, J.P.3
  • 118
    • 0027530096 scopus 로고
    • Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis
    • Ransohoff RM, Hamilton TA, Tani M, et al. Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J 1993; 7: 592-600.
    • (1993) FASEB J , vol.7 , pp. 592-600
    • Ransohoff, R.M.1    Hamilton, T.A.2    Tani, M.3
  • 119
    • 0035874640 scopus 로고    scopus 로고
    • CXCL10 (IFN-gamma-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis
    • Fife BT, Kennedy KJ, Paniagua MC, et al. CXCL10 (IFN-gamma-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol 2001; 166: 7617-7624
    • (2001) J Immunol , vol.166 , pp. 7617-7624
    • Fife, B.T.1    Kennedy, K.J.2    Paniagua, M.C.3
  • 120
    • 0036087256 scopus 로고    scopus 로고
    • Neutralization of IFN-inducible protein 10/CXCL10 exacerbates experimental autoimmune encephalomyelitis
    • Narumi S, Kaburaki T, Yoneyama H, Iwamura H, Kobayashi Y, Matsushima K. Neutralization of IFN-inducible protein 10/CXCL10 exacerbates experimental autoimmune encephalomyelitis. Eur J Immunol 2002; 32: 1784-1791
    • (2002) Eur J Immunol , vol.32 , pp. 1784-1791
    • Narumi, S.1    Kaburaki, T.2    Yoneyama, H.3    Iwamura, H.4    Kobayashi, Y.5    Matsushima, K.6
  • 122
    • 35349024802 scopus 로고    scopus 로고
    • CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system
    • Muller M, Carter SL, Hofer MJ, et al. CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system. J Immunol 2007; 179: 2774-2786
    • (2007) J Immunol , vol.179 , pp. 2774-2786
    • Muller, M.1    Carter, S.L.2    Hofer, M.J.3
  • 124
    • 7644231753 scopus 로고    scopus 로고
    • Transition from acute to persistent Theiler's virus infection requires active viral replication that drives proinflammatory cytokine expression and chronic demyelinating disease
    • DOI 10.1128/JVI.78.22.12480-12488.2004
    • Trottier M, Schlitt BP, Kung AY, Lipton HL. Transition from acute to persistent Theiler's virus infection requires active viral replication that drives proinflammatory cytokine expression and chronic demyelinating disease. J Virol 2004; 78: 12480-12488 (Pubitemid 39458766)
    • (2004) Journal of Virology , vol.78 , Issue.22 , pp. 12480-12488
    • Trottier, M.1    Schlitt, B.P.2    Kung, A.Y.3    Lipton, H.L.4
  • 125
    • 0028902180 scopus 로고
    • The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus-induced demyelinating disease
    • Lipton HL, Twaddle G, Jelachich ML. The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus-induced demyelinating disease. J Virol 1995; 69: 2525-2533
    • (1995) J Virol , vol.69 , pp. 2525-2533
    • Lipton, H.L.1    Twaddle, G.2    Jelachich, M.L.3
  • 126
    • 33845403776 scopus 로고    scopus 로고
    • T cell antiviral effector function is not dependent on CXCL10 following murine coronavirus infection
    • Stiles LN, Hardison JL, Schaumburg CS, Whitman LM, Lane TE. T cell antiviral effector function is not dependent on CXCL10 following murine coronavirus infection. J Immunol 2006; 177: 8372-8380
    • (2006) J Immunol , vol.177 , pp. 8372-8380
    • Stiles, L.N.1    Hardison, J.L.2    Schaumburg, C.S.3    Whitman, L.M.4    Lane, T.E.5
  • 127
    • 0038725881 scopus 로고    scopus 로고
    • Astrocytes produce CNTF during the remyelination phase of viral-induced spinal cord demyelination to stimulate FGF-2 production
    • Albrecht PJ, Murtie JC, Ness JK, et al. Astrocytes produce CNTF during the remyelination phase of viral-induced spinal cord demyelination to stimulate FGF-2 production. Neurobiol Dis 2003; 13: 89-101.
    • (2003) Neurobiol Dis , vol.13 , pp. 89-101
    • Albrecht, P.J.1    Murtie, J.C.2    Ness, J.K.3
  • 128
    • 0034667585 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 (FGF2) and FGF receptor expression in an experimental demyelinating disease with extensive remyelination
    • Messersmith DJ, Murtie JC, Le TQ, Frost EE, Armstrong RC. Fibroblast growth factor 2 (FGF2) and FGF receptor expression in an experimental demyelinating disease with extensive remyelination. J Neurosci Res 2000; 62: 241-256
    • (2000) J Neurosci Res , vol.62 , pp. 241-256
    • Messersmith, D.J.1    Murtie, J.C.2    Le, T.Q.3    Frost, E.E.4    Armstrong, R.C.5
  • 129
    • 51649118004 scopus 로고    scopus 로고
    • An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss
    • Hampton DW, Anderson J, Pryce G, et al. An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss. J Neuroimmunol 2008; 201-202: 200-211
    • (2008) J Neuroimmunol , vol.201-202 , pp. 200-211
    • Hampton, D.W.1    Anderson, J.2    Pryce, G.3
  • 130
    • 0016598060 scopus 로고
    • Progressive demyelination and reparative phenomena in chronic experimental allergic encephalomyelitis
    • Snyder DH, Valsamis MP, Stone SH, Raine CS. Progressive demyelination and reparative phenomena in chronic experimental allergic encephalomyelitis. J Neuropathol Exp Neurol 1975; 34: 209-221
    • (1975) J Neuropathol Exp Neurol , vol.34 , pp. 209-221
    • Snyder, D.H.1    Valsamis, M.P.2    Stone, S.H.3    Raine, C.S.4
  • 131
    • 0021966856 scopus 로고
    • T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination
    • Zamvil S, Nelson P, Trotter J, et al. T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination. Nature 1985; 317: 355-358
    • (1985) Nature , vol.317 , pp. 355-358
    • Zamvil, S.1    Nelson, P.2    Trotter, J.3
  • 132
    • 0034956124 scopus 로고    scopus 로고
    • Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis
    • Murray PD, McGavern DB, Sathornsumetee S, Rodriguez M. Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis. Brain 2001; 124: 1403-1416
    • (2001) Brain , vol.124 , pp. 1403-1416
    • Murray, P.D.1    McGavern, D.B.2    Sathornsumetee, S.3    Rodriguez, M.4
  • 133
    • 0035996192 scopus 로고    scopus 로고
    • New insights into remyelination failure in multiple sclerosis: Implications for glial cell transplantation
    • Chari DM, Blakemore WF. New insights into remyelination failure in multiple sclerosis: implications for glial cell transplantation. Mult Scler 2002; 8: 271-277
    • (2002) Mult Scler , vol.8 , pp. 271-277
    • Chari, D.M.1    Blakemore, W.F.2
  • 134
    • 0031024177 scopus 로고    scopus 로고
    • Transplanting oligodendrocyte progenitors into the adult CNS
    • DOI 10.1017/S0021878296008977
    • Franklin RJ, Blakemore WF. Transplanting oligodendrocyte progenitors into the adult CNS. J Anat 1997; 190 ( Pt 1): 23-33. (Pubitemid 27067599)
    • (1997) Journal of Anatomy , vol.190 , Issue.1 , pp. 23-33
    • Franklin, R.J.M.1    Blakemore, W.F.2
  • 135
    • 0030834978 scopus 로고    scopus 로고
    • Local recruitment of remyelinating cells in the repair of demyelination in the central nervous system
    • DOI 10.1002/(SICI)1097-4547(19971015)50:2<337::AID-JNR21>3.0.CO;2-3
    • Franklin RJ, Gilson JM, Blakemore WF. Local recruitment of remyelinating cells in the repair of demyelination in the central nervous system. J Neurosci Res 1997; 50: 337-344 (Pubitemid 27473648)
    • (1997) Journal of Neuroscience Research , vol.50 , Issue.2 , pp. 337-344
    • Franklin, R.J.M.1    Gilson, J.M.2    Blakemore, W.F.3
  • 136
    • 33644910475 scopus 로고    scopus 로고
    • Differences in the early inflammatory responses to toxin-induced demyelination are associated with the age-related decline in CNS remyelination
    • Zhao C, Li WW, Franklin RJ. Differences in the early inflammatory responses to toxin-induced demyelination are associated with the age-related decline in CNS remyelination. Neurobiol Aging 2006; 27: 1298-1307
    • (2006) Neurobiol Aging , vol.27 , pp. 1298-1307
    • Zhao, C.1    Li, W.W.2    Franklin, R.J.3
  • 137
    • 37849031596 scopus 로고    scopus 로고
    • Endogenous or exogenous oligodendrocytes for remyelination
    • Blakemore WF, Irvine KA. Endogenous or exogenous oligodendrocytes for remyelination. J Neurol Sci 2008; 265: 43-46
    • (2008) J Neurol Sci , vol.265 , pp. 43-46
    • Blakemore, W.F.1    Irvine, K.A.2
  • 138
    • 50249167673 scopus 로고    scopus 로고
    • Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
    • Shen S, Sandoval J, Swiss VA, et al. Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci 2008.
    • (2008) Nat Neurosci
    • Shen, S.1    Sandoval, J.2    Swiss, V.A.3
  • 139
    • 0036549138 scopus 로고    scopus 로고
    • The Age-Related Decrease in CNS Remyelination Efficiency Is Attributable to an Impairment of Both Oligodendrocyte Progenitor Recruitment and Differentiation
    • Sim FJ, Zhao C, Penderis J, Franklin RJ. The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J Neurosci 2002; 22: 2451-2459 (Pubitemid 37465793)
    • (2002) Journal of Neuroscience , vol.22 , Issue.7 , pp. 2451-2459
    • Sim, F.J.1    Zhao, C.2    Penderis, J.3    Franklin, R.J.M.4
  • 140
    • 0036720034 scopus 로고    scopus 로고
    • Why does remyelination fail in multiple sclerosis?
    • Franklin RJ. Why does remyelination fail in multiple sclerosis? Nat Rev Neurosci 2002; 3: 705-714
    • (2002) Nat Rev Neurosci , vol.3 , pp. 705-714
    • Franklin, R.J.1
  • 141
    • 0034705056 scopus 로고    scopus 로고
    • Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation
    • Liu S, Qu Y, Stewart TJ, et al. Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation. Proc Natl Acad Sci USA 2000; 97: 6126-6131
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6126-6131
    • Liu, S.1    Qu, Y.2    Stewart, T.J.3
  • 143
    • 0033618593 scopus 로고    scopus 로고
    • Embryonic stem cell-derived glial precursors: A source of myelinating transplants
    • Brustle O, Jones KN, Learish RD, et al. Embryonic stem cell-derived glial precursors: a source of myelinating transplants. Science 1999; 285: 754-756
    • (1999) Science , vol.285 , pp. 754-756
    • Brustle, O.1    Jones, K.N.2    Learish, R.D.3
  • 144
    • 0346494281 scopus 로고    scopus 로고
    • Intraventricular transplantation of neural precursor cell spheres attenuates acute experimental allergic encephalomyelitis
    • Einstein O, Karussis D, Grigoriadis N, et al. Intraventricular transplantation of neural precursor cell spheres attenuates acute experimental allergic encephalomyelitis. Mol Cell Neurosci 2003; 24: 1074-1082
    • (2003) Mol Cell Neurosci , vol.24 , pp. 1074-1082
    • Einstein, O.1    Karussis, D.2    Grigoriadis, N.3
  • 145
    • 84979726329 scopus 로고    scopus 로고
    • Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis
    • Pluchino S, Quattrini A, Brambilla E, et al. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature 2003; 422: 688-694
    • (2003) Nature , vol.422 , pp. 688-694
    • Pluchino, S.1    Quattrini, A.2    Brambilla, E.3
  • 146
    • 23644458723 scopus 로고    scopus 로고
    • Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice
    • Zhang J, Li Y, Chen J, et al. Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice. Exp Neurol 2005; 195: 16-26.
    • (2005) Exp Neurol , vol.195 , pp. 16-26
    • Zhang, J.1    Li, Y.2    Chen, J.3
  • 147
    • 0034254209 scopus 로고    scopus 로고
    • Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cells
    • Blakemore WF, Gilson JM, Crang AJ. Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cells. J Neurosci Res 2000; 61: 288-294
    • (2000) J Neurosci Res , vol.61 , pp. 288-294
    • Blakemore, W.F.1    Gilson, J.M.2    Crang, A.J.3
  • 148
    • 13544264789 scopus 로고    scopus 로고
    • Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation
    • Nistor GI, Totoiu MO, Haque N, Carpenter MK, Keirstead HS. Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation. Glia 2005; 49: 385-396
    • (2005) Glia , vol.49 , pp. 385-396
    • Nistor, G.I.1    Totoiu, M.O.2    Haque, N.3    Carpenter, M.K.4    Keirstead, H.S.5
  • 149
    • 2342611969 scopus 로고    scopus 로고
    • Remyelination, axonal sparing, and locomotor recovery following transplantation of glial-committed progenitor cells into the MHV model of multiple sclerosis
    • Totoiu MO, Nistor GI, Lane TE, Keirstead HS. Remyelination, axonal sparing, and locomotor recovery following transplantation of glial-committed progenitor cells into the MHV model of multiple sclerosis. Exp Neurol 2004; 187: 254-265
    • (2004) Exp Neurol , vol.187 , pp. 254-265
    • Totoiu, M.O.1    Nistor, G.I.2    Lane, T.E.3    Keirstead, H.S.4
  • 150
    • 30444459333 scopus 로고    scopus 로고
    • Transplantation of glial-committed progenitor cells into a viral model of multiple sclerosis induces remyelination in the absence of an attenuated inflammatory response
    • Hardison JL, Nistor G, Gonzalez R, Keirstead HS, Lane TE. Transplantation of glial-committed progenitor cells into a viral model of multiple sclerosis induces remyelination in the absence of an attenuated inflammatory response. Exp Neurol 2006; 197: 420-429
    • (2006) Exp Neurol , vol.197 , pp. 420-429
    • Hardison, J.L.1    Nistor, G.2    Gonzalez, R.3    Keirstead, H.S.4    Lane, T.E.5
  • 152
    • 33646872221 scopus 로고    scopus 로고
    • Cytokine-mediated modulation of MMPs and TIMPs in multipotential neural precursor cells
    • DOI 10.1016/j.jneuroim.2006.02.002, PII S0165572806000440
    • Ben-Hur T, Ben-Yosef Y, Mizrachi-Kol R, Ben-Menachem O, Miller A. Cytokine-mediated modulation of MMPs and TIMPs in multipotential neural precursor cells. J Neuroimmunol 2006; 175: 12-18 (Pubitemid 43786225)
    • (2006) Journal of Neuroimmunology , vol.175 , Issue.1-2 , pp. 12-18
    • Ben-Hur, T.1    Ben-Yosef, Y.2    Mizrachi-Kol, R.3    Ben-Menachem, O.4    Miller, A.5
  • 153
    • 0037254564 scopus 로고    scopus 로고
    • Transplanted multipotential neural precursor cells migrate into the inflamed white matter in response to experimental autoimmune encephalomyelitis
    • Ben-Hur T, Einstein O, Mizrachi-Kol R, et al. Transplanted multipotential neural precursor cells migrate into the inflamed white matter in response to experimental autoimmune encephalomyelitis. Glia 2003; 41: 73-80.
    • (2003) Glia , vol.41 , pp. 73-80
    • Ben-Hur, T.1    Einstein, O.2    Mizrachi-Kol, R.3
  • 154
    • 0347364630 scopus 로고    scopus 로고
    • Migration and differentiation of neural precursor cells can be directed by microglia
    • Aarum J, Sandberg K, Haeberlein SL, Persson MA. Migration and differentiation of neural precursor cells can be directed by microglia. Proc Natl Acad Sci USA 2003; 100: 15983-15988
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15983-15988
    • Aarum, J.1    Sandberg, K.2    Haeberlein, S.L.3    Persson, M.A.4
  • 155
    • 19944426191 scopus 로고    scopus 로고
    • Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway
    • Imitola J, Raddassi K, Park KI, et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci USA 2004; 101: 18117-18122
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 18117-18122
    • Imitola, J.1    Raddassi, K.2    Park, K.I.3
  • 157
    • 15044357461 scopus 로고    scopus 로고
    • Inflammation stimulates remyelination in areas of chronic demyelination
    • Foote AK, Blakemore WF. Inflammation stimulates remyelination in areas of chronic demyelination. Brain 2005; 128: 528-539
    • (2005) Brain , vol.128 , pp. 528-539
    • Foote, A.K.1    Blakemore, W.F.2
  • 158
    • 33748143936 scopus 로고    scopus 로고
    • Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells
    • Setzu A, Lathia JD, Zhao C, et al. Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells. Glia 2006; 54: 297-303.
    • (2006) Glia , vol.54 , pp. 297-303
    • Setzu, A.1    Lathia, J.D.2    Zhao, C.3
  • 162
    • 52149111208 scopus 로고    scopus 로고
    • Neuroprotective effect of transplanted human embryonic stem cell-derived neural precursors in an animal model of multiple sclerosis
    • Aharonowiz M, Einstein O, Fainstein N, Lassmann H, Reubinoff B, Ben-Hur T. Neuroprotective effect of transplanted human embryonic stem cell-derived neural precursors in an animal model of multiple sclerosis. PLoS ONE 2008; 3: e3145.
    • (2008) PLoS ONE , vol.3
    • Aharonowiz, M.1    Einstein, O.2    Fainstein, N.3    Lassmann, H.4    Reubinoff, B.5    Ben-Hur, T.6
  • 163
    • 34147190318 scopus 로고    scopus 로고
    • Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppression
    • Einstein O, Fainstein N, Vaknin I, et al. Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppression. Ann Neurol 2007; 61: 209-218
    • (2007) Ann Neurol , vol.61 , pp. 209-218
    • Einstein, O.1    Fainstein, N.2    Vaknin, I.3
  • 164
    • 33244487404 scopus 로고    scopus 로고
    • Transplanted neural precursor cells reduce brain inflammation to attenuate chronic experimental autoimmune encephalomyelitis
    • Einstein O, Grigoriadis N, Mizrachi-Kol R, et al. Transplanted neural precursor cells reduce brain inflammation to attenuate chronic experimental autoimmune encephalomyelitis. Exp Neurol 2006; 198: 275-284
    • (2006) Exp Neurol , vol.198 , pp. 275-284
    • Einstein, O.1    Grigoriadis, N.2    Mizrachi-Kol, R.3
  • 165
    • 0029751983 scopus 로고    scopus 로고
    • Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2
    • van Oosten BW, Barkhof F, Truyen L, et al. Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. Neurology 1996; 47: 1531-1534
    • (1996) Neurology , vol.47 , pp. 1531-1534
    • Van Oosten, B.W.1    Barkhof, F.2    Truyen, L.3
  • 166
    • 0023221133 scopus 로고
    • Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune system
    • Panitch HS, Hirsch RL, Schindler J, Johnson KP. Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurology 1987; 37: 1097-1102
    • (1987) Neurology , vol.37 , pp. 1097-1102
    • Panitch, H.S.1    Hirsch, R.L.2    Schindler, J.3    Johnson, K.P.4
  • 167
    • 48849087125 scopus 로고    scopus 로고
    • Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: A phase II, double-blind, placebo-controlled, randomised, dose-ranging study
    • Segal BM, Constantinescu CS, Raychaudhuri A, Kim L, Fidelus-Gort R, Kasper LH. Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study. Lancet Neurol 2008; 7: 796-804.
    • (2008) Lancet Neurol , vol.7 , pp. 796-804
    • Segal, B.M.1    Constantinescu, C.S.2    Raychaudhuri, A.3    Kim, L.4    Fidelus-Gort, R.5    Kasper, L.H.6


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