Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells

Journal of Virology

Volumn 82, Issue 1, 2008, Pages 300-310

  Ireland, Derek D C ^a   Stohlman, Stephen A ^a   Hinton, David R ^b   Atkinson, Roscoe ^b   Bergmann, Cornelia C ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CD8 ANTIGEN; GAMMA INTERFERON; INTERFERON; INTERFERON RECEPTOR; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CD8+ T LYMPHOCYTE; CELL PROTECTION; CELL SPECIFICITY; CELL TYPE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORONAVIRUS; DEMYELINATION; EFFECTOR CELL; GLIA CELL; INTERFERON PRODUCTION; MICROGLIA; MOUSE; NEUROTROPIC VIRUS; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRAIN DIFFERENCE; T LYMPHOCYTE ACTIVATION; VIROGENESIS; VIRUS INFECTION; VIRUS REPLICATION; VIRUS TYPING; WILD TYPE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM DISEASES; CHEMOKINE CCL2; CORONAVIRUS INFECTIONS; HISTOCOMPATIBILITY ANTIGENS CLASS I; INTERFERON TYPE I; INTERFERON TYPE II; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROGLIA; NEURONS; NEUTROPHILS; RECEPTOR, INTERFERON ALPHA-BETA; SURVIVAL ANALYSIS; TUMOR NECROSIS FACTOR-ALPHA;

CORONAVIRUS; MUS; RODENTIA;

EID: 37349029705     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01794-07     Document Type: Article

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