A quantification of pathway components supports a novel model of hedgehog signal transduction

Journal of Biological Chemistry

Volumn 284, Issue 42, 2009, Pages 28874-28884

  Farzan, Shohreh F ^a   Stegman, Melanie A ^a,c   Ogden, Stacey K ^a,b   Ascano Jr , Manuel ^a,e   Black, Kendall E ^a   Tacchelly, Ofelia ^a   Robbins, David J ^a,d  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^c Learning Technology Program   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL INFORMATION; CELLULAR CONTEXTS; CURRENT MODELS; DROSOPHILA CELLS; G PROTEIN; IN-VIVO; METAZOAN DEVELOPMENT; MOLAR EXCESS; MOLAR RATIO; ORDERS OF MAGNITUDE; PATHWAY COMPONENTS; PURIFIED PROTEIN; QUANTITATIVE ANALYSIS; QUANTITATIVE RESULT; SECRETED PROTEIN; SIGNALING COMPONENTS; STEADY-STATE CONCENTRATIONS; TRANS-MEMBRANE PROTEINS;

BIOINFORMATICS; SIGNAL TRANSDUCTION; SIGNALING; TRANSCRIPTION FACTORS;

CELL MEMBRANES;

COSTAL 2 PROTEIN; FUSED PROTEIN; REGULATOR PROTEIN; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; SUPPRESSOR OF FUSED PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DROSOPHILA; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; STEADY STATE; STOICHIOMETRY;

ANIMALS; CYTOSOL; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; INSECTS; KINESIN; MODELS, BIOLOGICAL; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

CUBITUS INTERRUPTUS; ERINACEIDAE; METAZOA;

EID: 70350418764     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.041608     Document Type: Article

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